The Advanced Genomics Core (AGC) is pleased to announce the addition of a second Illumina MiSeq to their available instrumentation. The Illumina MiSeq, a small-scale next-generation DNA sequencer, boasts read lengths up to 600 bp and yields up to 25 million reads. The highly-flexible MiSeq platform, is optimal for a variety of applications, including high-coverage, targeted sequencing to cost-efficient pilot/QC sequencing for large-scale next-generation sequencing projects.

To address longer read demands, the Advanced Genomics Core NGS services will also be expanding to include an Oxford Nanopore Technologies (ONT) GridION system. ONT technology allows for a multitude of analysis currently not available on campus at a production level scale, including direct RNA/DNA sequencing, long read sequencing, modified base sequencing.

“The GridION will fill a unique space in advanced genomics research at U-M and provide a complementary technology to our short read, low error Illumina sequencers,” explained Olivia Koues, Ph.D., Managing Director of the Advanced Genomics Core.  “We’re pleased to continue to evolve to best meet the needs of our researchers.”

More details will be announced in the fall.