The Advanced Genomics Core

mission is to facilitate research in cutting-edge fields of genetics and genomics by implementing complex technologies. Chief among these is “next-generation” sequencing (NGS), which has revolutionized research in virtually all biological fields in the past decade. By housing NGS and companion genomic technologies in a single facility, we provide centralized expertise in advanced methods that enables all researchers to effectively exploit them for making scientific discoveries.

Getting Started


AGC News and Event Information

Request Services

The Advanced Genomics Core uses MiCores for requesting services, project communication, and invoicing/billing.


Advanced Genomics Core pricing and tool for estimating the cost of projects.

Input Requirements

General information for recommended minimum input, volume, and buffer requirements for standard AGC assays.

Preparing Samples

Information regarding aliquoting and labeling samples for submission to the AGC.

Drop-Off Instructions

Information regarding sample drop-off procedures.

AGC Data

Detailed information for retrieving your data.

Research Support

Information and materials for writing grant proposals, planning experiments, and publishing AGC generated data.

Core Policies

Information regarding sample processing and data retention policies.

Core Testimonials

“The BRCF has been an incredible partner in our sequencing efforts from large-scale bulk sequencing to boutique full-length splice isoform studies of single-cell data sets. And all this in times of a pandemic and for studies of our patients with COVID associated AKI.”

Dr. Matthias Kretzler

“The AGC has been an excellent provider for our team’s sequencing needs including support for library preparations and sequencing. Because of these core services, we have been able to focus our effort on validation approaches and understanding the biological significance of sequencing-based discoveries.” 

Dr. Chad Brenner

“BRCF’s Advanced Genomics Core made a huge impact on our research when we were at Michigan. This is something that we miss greatly as we moved to the University of Texas Houston last summer. The BRCF Core is a tremendous asset of the Michigan research community, and you do amazing work!”

Dr. Noriaki Ono

Our Locations:

North Campus Research Complex Building 14 (NCRC), Rm 122
Medical Science Research Building II (MSRB), Rm C562

How to Get Samples to the Core

Virtual Office Hours


  • The BRCF is Growing

    The BRCF and the Department of Pathology have come together to transition the Proteomics Resource Facility (PRF), led by Dr. Alexey Nesvizhskii, into the BRCF where it will continue to offer resources and services through the BRCF. The Proteomics Resource …

  • CRISPR/Cas9 Training Class Offered by TAMC, January 16 – 27, 2023

    The University of Michigan Transgenic Animal Model Core will offer the CRISPR/Cas9 and Mouse ES Cell Training Class from January 16 through January 27. In this two-week long hands-on session, trainees will design, build, and validate CRISPR/Cas9 reagents in mouse …



  • Proteomics Seminar

    Save the date! More details and registration will be provided soon. The Proteomics & Peptide Synthesis Core is excited to announce the next proteomics seminar, which will discuss new applications in proteomics for clinical research. The BRCF Proteomics & Peptide …

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