Advanced Genomics

Advanced Genomics and Next Generation Sequencing

  • All non-Sanger and non-Fragment Analysis service requests now use MiCores.

  • Coming Fall 2019! The Advanced Genomics Core services will be expanding to include an Oxford Nanopore Technologies (ONT) GridION system. Stay tuned…

Welcome to the Advanced Genomics Core

Olivia Koues, Ph.D.
Managing Director

The University of Michigan Advanced Genomics Core (formerly the DNA Sequencing Core), part of the Biomedical Research Core Facilities within the Office of Research, provides high-quality, low-cost advanced genomic analysis for research clients on a recharge basis. The Core occupies approximately 10,000 square feet of laboratory space in the North Campus Research Complex, with 30 highly trained individuals on staff to help you. We operate a wide variety of instruments that perform Sanger sequencing, genotyping, gene expression analysis, nucleic acid quantification, next-generation sequencing and single cell analysis.

The Advanced Genomics Core is growing and changing to adapt to the latest technologies and trends on a daily basis. We are a full-service Core, and work closely with our investigators to meet their needs and make their research as successful as possible.

Contact us with any questions!

Photos from Our Lab

Advanced Genomics by the Numbers

Grants Serviced FY18

Principal Investigators Served FY18

Joined BRCF


  • AGC and 10x Genomics Office Hours

    Bring your experimental design or analysis questions for our experts! Meet your Advanced Genomics Core team and learn more about the new and exciting technologies we are bringing to U-M.  Office hours will be held in the Taubman Library. Representatives …

  • 10x Genomics Visium Spatial Gene Expression Seminar

    Sponsored by the Advanced Genomics Core and featuring Keith Cockrum, Technical Sales Specialist, 10x Genomics The ability to discern spatial gene expression differences in complex biological systems is critical to our understanding of developmental biology and the progression of disease. However, …



  • AGC Increases Instrumentation Offerings with New Illumina MiSeq & ONT GridION System

    The Advanced Genomics Core (AGC) is pleased to announce the addition of a second Illumina MiSeq to their available instrumentation. The Illumina MiSeq, a small-scale next-generation DNA sequencer, boasts read lengths up to 600 bp and yields up to 25 …

  • CRISPR/Cas9 Training Class Offered by TAMC, Nov. 4 – Nov. 15

    The University of Michigan Transgenic Animal Model Core will offer the CRISPR/Cas9 and Mouse ES Cell Training Class from November 4 through November 15. In this two-week long hands-on session trainees will design, build, and validate CRISPR/Cas9 reagents in mouse ES cells. Trainees will …