Epigenomics Core Rates 

For external pricing, please contact Claudia Lalancette, Managing Director, Epigenomics Core.

Sample Quality Control & Preparations

Service RequestedUnitInternal Rate (U-M)
Sample Quality Control only (Qubit and TapeStation)per sample$22
Sample Quality Control and Bisulfite Treatmentper sample$27
PCR Reaction (for locus-specific assays; includes TapeStation QC)per sample$25
DNA Extraction & Quality Controlper assay$33
Cryopulverization of flash frozen tissuesper sample$40
nuclei preparation from flash frozen tissues (includes cryopulverization material and labor) (materials + labor) - NEWper sample$62
nuclei preparation from fresh or cryopreserved cells (materials + labor) - NEWper sample$37

Library Preparation

Service RequestedUnitInternal Rate (U-M)
WGBS (includes sample QC and library QC/quant)per assay$227
mERRBS (includes sample QC and library QC/quant)per assay$233
ChIP-seq library (includes sample QC and library QC/quant)per assay$162
ATAC-Seq library prep (includes library QC/quant; nuclei prep depends on material)per assay$202
Amplicon Bisulfite-Seq library preparation (library QC/quant)per assay$83
5hMeDIP-Seq (includes sample QC and library QC/quant)per sample$235
Sample Preparation Labor Rateper hour$100
Pyrosequencingfull plate$363
OxBS-Seq Preparationper samplecontact core

Sequencing Costs (with Advanced Genomics Core)

NovaSeq 6000UnitInternal Rate (U-M)
Illumina NovaSeq 6000 (SP) 100 Cycle Sequencingper flow cell$3,972
Illumina NovaSeq 6000 (SP) 300 Cycle Sequencingper flow cell$4,973
Illumina NovaSeq 6000 (SP) 500 Cycle Sequencingper flow cell$6,309
Illumina NovaSeq 6000 (S1) 100 Cycle Sequencingper flow cell$6,292
Illumina NovaSeq 6000 (S1) 200 Cycle Sequencingper flow cell$7,405
Illumina NovaSeq 6000 (S1) 300 Cycle Sequencingper flow cell$7,850
Illumina NovaSeq 6000 (S2) 100 Cycle Sequencingper flow cell$10,471
Illumina NovaSeq 6000 (S2) 200 Cycle Sequencingper flow cell$12,418
Illumina NovaSeq 6000 (S2) 300 Cycle Sequencingper flow cell$13,086
Illumina NovaSeq 6000 (S4) 200 Cycle Sequencingper flow cell$18,476
Illumina NovaSeq 6000 (S4) 300 Cycle Sequencingper flow cell$20,408

Illumina Infinium MethylationEPIC array (with Advanced Genomics Core)

NOTE: One array requires 16 samples. Cost is greater if fewer than 16 hybridizations are requested. For pricing, please contact Claudia Lalancette, Managing Director, Epigenomics Core.