The Microscopy Core
provides access to advanced light and electron microscopes as well as the expertise of dedicated imaging scientists. We provide custom image analysis, comprehensive sample preparation for electron microscopy, as well as clearing and expansion for light microscopy.
Please also take advantage of our imaging-related learning resources.
The Microscopy Core owns a basic transmission electron microscope (TEM) and scanning electron microscope (SEM) that are suitable for a large majority of biological EM imaging applications. For more specialized techniques, we have partnered with the Engineering School’s Michigan Center for Materials Characterization (MC2) to use their instruments. Core staff will still perform sample prep and in most cases can also train users on MC2 microscopes.
The Microscopy Core houses a wide range of light microscopes and imaging systems in the following three locations: BSRB A830, MSII 5631, and NCRC B20 57S. These instruments support a variety of imaging modalities, as described on the Light Microscopy page. Please contact us during the planning stage of your project to help you select the most appropriate methodology for your research needs.
“The BRCF Microscopy Core is critical to my lab’s ability to adopt new techniques and innovate. As a junior investigator working in neuroscience and immunology, I am constantly seeking better ways to study brain structure and neuroimmune activation. The resources of the Microscopy Core make it possible to experiment with different techniques without having to commit my lab to the costs of a single instrument and single technique. Collaborating with the core staff is a great way to push forward into new areas and take advantage of their evolving expertise regarding cutting-edge imaging techniques and technologies.”
“Gaining biological insight from access to the advanced super-resolution and 3D imaging microscopes in the BRCF Microscopy Core has been critical to the success of our recent grant applications and submissions of manuscripts. The staff have also been incredibly helpful for training and data analysis.”
The BRCF is Growing
The BRCF and the Department of Pathology have come together to transition the Proteomics Resource Facility (PRF), led by Dr. Alexey Nesvizhskii, into the BRCF where it will continue to offer resources and services through the BRCF. The Proteomics Resource …Services Instrumentation Breaking News
CRISPR/Cas9 Training Class Offered by TAMC, January 16 – 27, 2023
The University of Michigan Transgenic Animal Model Core will offer the CRISPR/Cas9 and Mouse ES Cell Training Class from January 16 through January 27. In this two-week long hands-on session, trainees will design, build, and validate CRISPR/Cas9 reagents in mouse …Event Breaking News
Save the date! More details and registration will be provided soon. The Proteomics & Peptide Synthesis Core is excited to announce the next proteomics seminar, which will discuss new applications in proteomics for clinical research. The BRCF Proteomics & Peptide …Event