Publications

Publications

AuthorsYearPublication
Schon SB, Yang K, Schindler R, Jiang L, Neff LM, Seeley RJ, Marsh EE.2022Obesity-related alterations in protein expression in human follicular fluid from women undergoing in vitro fertilization. F S Sci. 2022. PMID: 36096447
Geng X, Wang C, Gao X, Chowdhury P, Weiss J, Villegas JA, Saed B, Perera T, Hu Y, Reneau J, Sverdlov M, Wolfe A, Brown N, Harms P, Bailey NG, Inamdar K, Hristov AC, Tejasvi T, Montes J, Barrionuevo C, Taxa L, Casavilca S, de Pádua Covas Lage JLA, Culler HF, Pereira J, Runge JS, Qin T, Tsoi LC, Hong HS, Zhang L, Lyssiotis CA, Ohe R, Toubai T, Zevallos-Morales A, Murga-Zamalloa C, Wilcox RA2022GATA-3 is a proto-oncogene in T-cell lymphoproliferative neoplasms. Blood Cancer J. 2022. PMID: 36329027
Bhattacharya A, Wei J, Song W, Gao B, Tian C, Wu SA, Wang J, Chen L, Fang D, Qi L.2022Sel1L-HRD1 ER-associated degradation suppresses hepatocyte hyperproliferation and liver cancer. iScience 2022:25(10). PMID: 36238898
Kathania M, Kumar R, Lenou ET, Basrur V, Theiss AL, Chernoff J, Venuprasad K.2022Pak2-mediated phosphorylation promotes ROR_t ubiquitination and inhibits colonic inflammation. Cell Rep. 2022 40(11):111345. doi: 10.1016/j.celrep.2022.111345. PMID: 36103814
Wright SE, Rodriguez CM, Monroe J, Xing J, Krans A, Flores BN, Barsur V, Ivanova MI, Koutmou KS, Barmada SJ, Todd PI.2022CGG repeats trigger translational frameshifts that generate aggregation-prone chimeric proteins. Nucleic Acids Res. 2022, 50(15):8674-8689. PMID: 35904811
Yang J, Chang Y, Tien JC, Wang Z, Zhou Y, Zhang P, Huang W, Vo J, Apel IJ, Wang C, Zeng VZ, Cheng Y, Li S, Wang GX, Chinnaiyan AM, Ding K.2022Discovery of a Highly Potent and Selective Dual PROTAC Degrader of CDK12 and CDK13. J Med Chem. 2022 Aug 25;65(16):11066-11083. doi: 10.1021/acs.jmedchem.2c00384. Epub 2022 Aug 8. PMID: 35938508
Abbineni PS, Tang VT, da Veiga Leprevost F, Basrur V, Xiang J, Nesvizhskii AI, Ginsburg D.2022Identification of secreted proteins by comparison of protein abundance in conditioned media and cell lysates. Anal. Biochem. 2022. PMID: 35973625
Hotta T, McAlear TS, Yue Y, Higaki T, Haynes SE, Nesvizhskii AI, Sept D, Verhey KJ, Bechstedt S, Ohi R.2022EML2-S constitutes a new class of proteins that recognizes and regulates the dynamics of tyrosinated microtubules. Curr Biol. 2022 Aug 6:S0960-9822(22)01128-9. PMID: 35963242
Herber I, Zedan D, McClintock S, Varani J, Aslam MN.2022Liver proteomic profile in mice on a high-far diet: Modulation with anti-tumor intervention. FASEB J. 2022. PMID: 35556832
Cerqueira FM, Photenhauer AL, Doden HL, Brown AN, Abdel-Hamid AM, Morais S, Bayer EA, Wawrzak Z, Cann I, Ridlon JM, Hopikins J, Koropatkin NM.2022Sas20 is a highly flexible starch-binding protein in the Ruminococcus bromii cell-surface amylosome. J. Biol. Chem. 2022. PMID: 35378131
Ostrowski MP, La Rosa SL, Kunath BJ, Pereira G, Hagen LH, Varghese NJ, Qiu L, Yao T, Flint G, Li J, McDonald SP, Buttner D, Pudlo NA, Schnizlein MK, Young VB, Brumer H, Schmidt TM, Terrapon N, Lombard V, Henrissat B, Hamaker B, Eloe-Fadrosh EA, Tripathi A, Pope PB, Martens EC.2022Mechanistic insights into consumption of the food additive zanthan gum by the human gut microbiota. Nat. Microbiol. 2022. PMID: 35365790
Varani J, McClintock SD, Aslam MN.2022Cell-matrix interactions contribute to barrier function in human colon organoids. Front. Med. (Lausanne), 2022. PMID: 35360746
Mohan HM, Trzeciakiewicz H, Pithadia A, Crowley EV, Pacitto R, Safren N, Trotter B, Zhang C, Zhou X, Zhang Y, Basrur V. Paulson HL, Sharkey LM.2022RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control. Cell Mol. Life Sci. 2022, 79(3):176. PMID: 35247097
Boyer S, Lee HJ, Steele N, Zhang L, Sajjakulnukit P, Andren A, Ward MH, Singh R, Basrur V, Zhang Y, Nesvizhskii AI, Pasca di Magliano M, Halbrook CJ, Lyssiotis CA.2022Multiomic characterization of pancreatic cancer-associated macrophage polarization reveals deregulated metabolic programs driven by the GM-CSF-PI3K pathway. Elife. 2022 Feb 14;11:e73796. doi: 10.7554/eLife.73796.PMID: 35156921
Zhang Y, Glineburg MR, Basrur V, Conlon K, Wright SE, Krans A, Hall DA, Todd PK.2022Mechanistic convergence across initiation sites for RAN translation in fragile X associated tremor ataxia syndrome. Hum. Mol. Genet. 2022, PMID: 35137065
Chandan NR, Abraham S, SenGupta S, Parent CA, Smrcka AV.2022A network of G-alpha-i signaling partners is revealed by proximity labeling proteomics analysis and includes PDZ-RhoGEF. Sci. Signal. 2022. PMID: 35041463
Xiao L, Parolia A, Qiao Y, Bawa P, Eyunni S, Mannan R, Carson SE, Chang Y, Wang X, Zhang Y, Vo JN, Kregel S, Simko SA, Delekta AD, Jaber M, Zheng H, Apel IJ, McMurry L, Su F, Wang R, Zelenka-Wang S, Sasmal S, Kare L, Mukherjee S, Abbineni C, Aithal K, Bhakta MS, Ghurye J, Cao X, Navone NM, Nesvizhskii AI, Mehra R, Vaishampayan U, Blanchette M, Wang Y, Samjdar S, Ramachandra M, Chinnaiyan M.2021Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer. Nature 2021. PMID: 34937944
Weber SR, Zhao Y, Ma J, Gates C, da Veiga Leprevost F, Basrur V, Nesvizhskii AI, Gardner TW, Sundrstrom JM.2021A validated analysis pipeline for mass spectrometry-based vitreous proteomics: New insights into proliferative diabetic retinopathy. Clin. Proteomics 2021, 18(1):28. PMID: 34861815
Solon AL, Tan Z, Schutt KL, Jepsen L, Haynes SE, Nesvizhskii AI, Sept D, Stumpff J, Ohi R, Cianfrocco MS.2021Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding. Sci. Adv. 2021. PMID: 34797717
Panwalkar P......Venneti S.2021Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas. Sci. Transl. Med. 2021, 13(614):eabc0497. PMID: 34613815
Malik I, Tseng YJ, Wright SE, Zheng K, Ramaiyer P, Green KM, Todd PK.2021SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity. EMBO Mol. Med., 2021, 13(11):e14163. PMID: 34542927
Sheedlo MJ, Durie CL, Chung JM, Chang L, Roberts J, Swanson M, Lacy DB, Ohi MD.2021Cryo-EM reveals new species-specific proteins and symmetry elements in the legionells pneumophila Dot/Icm T4SS. Elife 2021. PMID: 34519271
Kearns S, Mason FM, Rathmell WK, Park IY, Walker C, Verhey KJ, Cianfrocco MA.2021Molecular determinants for alpha-tubulin methylation by SETD2. J. Biol. Chem. 2021, 297(1)100898. PMID: 34157286
Alford AI, Stephan C, Kozloff KM, Hankenson KD.2021Compound deletion of thrombosponding-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts. Bone, 2021. PMID: 34425286
Venkatesan A, Geng J, Kandarpa M, Wijeyesakere SJ, Bhide A, Talpaz M, Pogozheva ID, Raghavan M.2021Mechanism of mutant calreticulin-mediated activation of the thrombopoietin receptors in cancers. J. Cell Biol. 2021, 220(7)e20209179. PMID: 33909030
Singhal R, Mitta SR, Das NK, Kerk SA, Sajjakulnukit P, Solanki S, Andren A, Kumar R, Olive KP, Banerjee R, Lyssiotis CA, Shah YM.2021HIF-2a activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron. J. Clin. Invest. 2021, 15:131(12)e143691. PMID: 33914705
Zhou H, Bai L, Xu R, McEachern D, Chinnaswamy K, Li R, Wen B, Wang M, Yang CY, Meagher JL, Sun D, Stuckey JA, Wang S.2021SD-91 as a potent and selective STAT3 degrader capable of achieving complete and long-lasting tumor regression. ACS Med. Chem Lett. 2021, 12(6):996-1004. PMID: 34141084
Weber SR, Zhao Y, Gates C, Ma J, da Veiga Leprevost F, Basrur V, Nesvizhskii AI, Garder TW, Sundstrom JM.2021Proteomic analyses of vitreous in proliferative diabetic retinopathy: Prior studies and future outlook. J. Clin. Med. 2021, 01(11):2309. PMID: 34070658
Grunkemeyer TJ, Ghosh S, Patel AM, Sajja K, Windak J, Basrur V, Kim Y, Nesvizhskii AI, Kennedy RT, Marsh ENG.2021The antiviral enzyme viperin inhibits cholesterol biosynthesis. J. Biol. Chem. 2021. 297(1):100824. PMID: 34029588
Zhou H, Lu J, Chinnaswamy K, Stuckey JA, Liu L, McEachern D, Yand CY, Bernard D, Shen H, Rui L, Sun Y, Wang S.2021Selective Inhibition of cullin 3 neddylation through covalent targeting of DCN1 protects mice from acetaminophen-induced liver toxicity. Nat. Commun. 2021, 12(1):2621. PMID: 33976147
Wang S, Lin CW, Carleton AE, Cortex CL, Johnson C, Taniguchi LE, Sekulovski N, Townsend RF, Basrur V, Nesvizhskii AI, Zou P, Fu J, Gumucio DL, Duncan MC, Taniguchi K.2021Spatially resolved cell polarity proteomics of a human epiblast model. Sci. Adv. 2021, 7(17):eabd8407. PMID: 33893097
Felker D, Zhang H, Bo Z, Lau M, Morishima Y, Scnell S, Osawa Y.2021Mapping protein-protein interactions in homodimeric CYP102A1 by crosslinking and mass spectrometry. Biophys. Chem. 2021. PMID: 33894563
Aslam MN, McClintock SD, Jawad-Makki MAH, Knuver K, Ahmad HM, Basrur V, Bergin IL, Zick SM, Sen A, Turgeon DK, Varani J.2021A Multi-mineral intervention to modulate colonic mucosal protein profile: Results from a 90-day trial in human subjects. Nutrients, 2021, 13(3):939. PMID: 33799486
Hanafi M, Chen X, Neamati N.2021Discovery of a Napabucasin PROTAC as an effective degrader of the E3 ligase ZFP91. J. Med. Chem. 2021, 64(3):1626-1648. PMID: 33506674
Hotta T, Haynes SE, Blasius TL, Gebbie M, Eberhardt EL, Sept D, Cianfrocco M, Verhey KJ, Nesvizhskii AI, Ohi R.2021Parthenolide Destabilizes Microtubules by Covalently Modifying Tubulin. Curr Biol. 2021, 31(4):900-907. PMID: 33482110
Korwar AM, Hossain A, Lee TJ, Shay AE, Basrur V, Conlon K, Smith PB, Carlson BA, Salis HM, Patterson AD, Prabhu KS.2021Selenium-dependent metabolic reprogramming during inflammation and resolution. J. Biol. Chem. 2021. PMID: 33581115
Kim S, Khoriaty R, Li L, McClune M, Kalfa TA, Wu J, Fujiwara H, Sun Y, Oravecz-Wilson K, King RA, Ginsburg D, Reddy P.2021ER-to-golgi transport and Sec23-dependent COPII vesicles regulate T cell allimmunity. J. Clin. Invest. 2021, 131(2)e136474. PMID: 33463537
Xu J, Zhao X, Mao F, Basrur V, Ueberheide B, Chait BT, Allis CD, Taverna SD, Gao S, Wang W, Liu Y.2021A polycomb repressive complex is required for RNAi-mediated heterchromatin formation and dynamic distribution of nuclear bodies. Nucleic Acids Res. 2021. PMID:33412588
Tong X, Zhang D, Shabandri O, Oh J, Jin E, Stamper K, Yang M, Zhao Z, Yin L.2020DDB1 E3 ligase controls dietary fructose-induced ChREBPalpha stabilization and liver steatosis via CRY1. Metabolism 2020. 107:154222. PMID: 32246987
Shergalis A, Xue D, Gharbia FZ, Drinks H, Shrestha B, Tanweer A, Cromer K, Ljungman M, Neamati N.2020Characterization of aminobenzylphenols as protein disulfide isomerase inhibitors in glioblastoma cell lines. J. Med. Chem. 2020, 63(18):10263-10286. PMID: 32830969
Sheedlow MJ, Chung JM, Sawhney N, Duries CL, Cover TL, Ohi MD, Lacy DB.2020Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex. Elife. 2020. 9:e59495. PMID: 32876048
Xu Y, Bankhead A 3rd, Tian X, Tang J, Ljungman M, Neamati N.2020Deletion of Glutathione S-Transferase Omega 1 Activates Type I Interferon Genes and Downregulates Tissue Factor. Cancer Res. 2020, 80(17):3692-3705. PMID: 32571799
Schneider DJ, Smith KA, Latuszek CE, Wilke CA, Lyons DM, Penke LR, Speth JM, Marthi M, Swanson JA, Moore BB, Lauring AS, Peters-Golden M.2020Alveolar macrophage-derived extracellular vesicles inhibit endosomal fusion of influenza virus. EMBO J. 2020, 39(16):e105057. PMID: 32643835
Aslam MN, McClintock SD, Addili D, Pandya S, Rehman H, Nadeem DM, Jawad-Makki MAH, Rizvi AH, Brenner MM, Dame MK, Turgeon DK, Varani J.2020Ulcertative colitis-derived colonoid culture: A multi-mineral-approach to improve barrier protein expression. Front Cell Dev. Biol. 2020, 8:577221. PMID: 33330453
Duan Y, Zhang L, Angosto-Bazarra D, Pelegrin P, Nunez G, He Y.2020RACK1 mediates NLRP3 inflammasome activation by promoting NLRP3 active conformation and inflammasome assembly. Cell Rep. 2020, 33(7):108405. PMID: 33207200
Chung C, Sweha SR, Pratt D, Tamrazi B, Panwalkar P, Banda A, Bayliss J, Hawes D, Yang F, Lee HJ, Shan M, Cieslik M, Qin T, Wener CK, Wahl DR, Lyssiotis CA, Bian Z, Shotwell JB, Yadav VN, Koschmann C, Chinnaiyan AM, Bluml S, Judkins AR, Venneti S.2020Integrated metabolic and epigenomic reprograming by H3K27M mutations in diffuse intrinsic Pontine gliomas. Cancer Cell, 2020, 38(3)334-349. PMID: 32795401
Mohan HM, Yang B, Dean NA, Raghavan M.2020Calreticulin enhances the secretory trafficking of a misfolded alpha-1-antitrypsin. J. Biol. Chem. 2020, 295(49):16754-16772. PMID: 32978262
Durie CL, Sheedlo MJ, Chung JM, Burne BG, Su M, Knight T, Swanson M, Lacy DB, Ohi MD.2020Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex. Elife. 2020. PMID: 32876045
Mehta RK, Pal S, Kondapi K, Sitto M, Dewar C, Devasia T, Schipper MJ, Thomas DG, Basrur V, Pai MP, Morishima Y, Osawa Y, Pratt WB, Lawrence TS, Nyati MK.2020Low-dose Hsp90 inhibitor selectively radiosensitizes HNSCC and pancreatic xenografts. Clin. Cancer Res. 2020. PMID: 32718999
Ray P, Raghunathan K, Ahsan A, Allam US, Shukla S, Basrur V, Veatch S, Lawrence TS, Nyati MK, Ray D.2020Ubiquitin ligase SMURF2 enhances epidermal growth factor receptor stability and tyrosine-kinase inhibitor resistance. J. Biol. Chem. 2020, 295(36):12661-12673. PMID: 32669362
Park SS, Ponce-Balbuena D, Kuick R, Guerrero-Serna G, Yoon J, Mellacheruvu D, Conlon KP, Basrur V, Nesvizhskii AI, Jalife J, Rual JF.2020Kir2.1 interactome mapping uncovers PKP4 as a modulator of the Kir2.1-regulated inward rectifier potassium currents. Mol. Cell Proteomics. 2020 PMID: 32541000
Mukherjee S, Kumar R, Tsakem Lenou E, Basrur V, Kontoyiannis DL, Ioakeimidis F, Mosialos G, Theiss AL, Flavell RA, Venuprasad K.2020Deubiquitination of NLRP6 inflammasome by Cyld critically regulates intestinal inflammation. Nat. Immunol. 2020, 21(6):626-635. PMID: 32424362
Khatri Y, Hohlman RM, Mendoza J, Li S, Lowell AN, Asahara H, Sherman DH.2020Multicomponent microscale biosynthesis of unnatural cyanobacterial indole alkaloids. ACS Synth. Biol. 2020 PMID: 32302487
Nyati S, Gregg BS, Xu J, Young G, Kimmel L, Nyati MK, Ray D, Speers C, Rehemtulla A.2020TGFBR2 mediated phosphorylation of BUB1 at Ser-318 is required for transforming growth factor-b signaling. Neoplasia 2020, 22(4):163-178. PMID: 32143140
Saffie R, Zhou N, Rolland D, Onder O, Basrur V, Campbell S, Wellen KE, Elenitoba-Johnson KSJ, Capell BC, Busino L.2020FBXW7 triggers degradation of KMT2D to favor growth of diffuse large B-cell lymphoma cells. Cancer Res. 2020, 21(6):626-635 PMID:32350066
Kang J, Kim SY, Vallejo D, Hageman TS, White DR, Benet A, Coghlan J, Sen KI, Ford M, Saveliev S, Tolbert TJ, Weis DD, Schwendeman SP, Routolo BT, Schwendeman A.2020Multifaceted assessment of rituximab biosimilarity: The impact of glycan microheterogeneity on Fc function. Eur. J. Pharm. Biopharm. 2020, 146:114-124. PMID: 31841688
Djomehri SI, Gonzalez ME, da Veiga Leprevost F, Tekula SR, Chang HY, White MJ, Cimino-Mathews A, Burman B, Basrur V, Argani P, Nesvizhskii AI, Kleer CG.2020Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors. Nat. Commun. 2020, 11(1):1723 PMID: 32265444
Cheng X, Mell B, Alimadadi A, Galla S, McCarthy CG, Chakraborty S, Basrur V, Joe B.2020Genetic predisposition for increased red blood cell distribution width is an early risk factor for cardiovascular and renal comorbidities. Dis. Model Mech. 2020 PMID: 32238420
Kregel S, Wang C, Han X, Xiao L, Fernandez-Salas E, Bawa P, McCollum BL, Wilder-Romans K, Apel IJ, Cao X, Speers C, Wang S, Chinnaiyan AM.2020Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment. Neoplasia 2020, 22(2)111-119. PMID: 31931431
Kowalsky AH, Namkoong S, Mettetal E, Park H-W, Kazyken D, Fingar DC, Lee JH.2020The GATOR2-mTORC2 axis mediates sestrin2-induced AKT ser/thr kinase activation. J. Biol. Chem. 2020 PMID: 31915252
Mitchell DC, Menon A, Garner AL.2019Cyclin-dependent kinase 4 inhibits the translational repressor 4E-BP1 to promote cap-dependent translation during mitosis-G1 transition. FEBS Lett. 2019 PMID:31853978
Rowlands RA, Cato MC, Waldschmidt HV, Boulley RA, Chen Q, Avramova L, Larsen SD, Tesmer JJG, White AD.2019Structure-Based Design of Selective, Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors. ACS Med. Chem Lett. 2019, 10(12):1628-1634. PMID: 31857838
Sherman EJ, Mitchell DC, Garner AL.2019The RNA-binding protein SART3 promotes miR-34a biogenesis and G1 cell cycle arrest in lung cancer cells. J. Biol. Chem. 2019, 294(46):17188-17196. PMID: 31619517
Rajan SS, Amin AD, Li L, Rolland DC, Li H, Kwon D, Kweh MF, Arumov A, Roberts ER, Yan A, Basrur V, Elenitoba-Johnson KSJ, Chen XS, Puvvada SD, Lussier YA, Bilbao D, Lim MS, Schatz JH.2019The mechanism of cancer drug addiction in ALK-positive T-cell Lymphoma. Oncogene, 2019.
Kruger AN, Brogley MS, Huizinga JL, Kidd JM, de Rooij DG, Hu YC, Mueller JL.2019A neofunctionalized X-linked ampliconic gene family is essential for male fertility and equal sex ratio in mice. Curr. Biol. 2019, 29(21):3699-3706.
Bail L, Zhou H, Xu R, Zhao Y, Chinnaswamy K, McEachem D, Chen J, Yang CY, Liu Z, Wang M, Liu L, Jiang H, Wen B, Kumar P, Meagher JL, Sun D, Stuckey JA, Wang S.2019A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo. Cancer Cell 2019, 36(5):498-511. PMID:31715132
Alcedo KP, Guerrero A, Basrur V, Fu D, Richardson ML, McLane JS, Tsou CC, Nesvizhskii AI, Welling TH, Lebrilla CB, Otey CA, Kim HJ, Omary MB, Snider NT.2019Tumor-selective altered glycosylation and functional attenuation of CD73 in human hepatocellular carcinoma. Hepatol. Commun. 2019, 3(10):1400-1414. PMID: 31592495
Lu T, Bankhead A III, Ljungman M, Neamati N.2019Multi-omics profiling reveals key signaling pathways in ovarian cancer controlled by STAT3. Theranostics 2019, 9(19):5478-5496. PMID:31534498
Attili D, McClintock SD, Rizvi AH, Pandya S, Rehman H, Nadeem DM, Richter A, Thomas D, Dame MK, Turgeon DK, Varani J, Aslam MN.2019Calcium-induced differentiation in normal human colonoid cultures: cell-cell/cell-matrix adhesion, barrier formation and tissue integrity. PLoS One 2019, 14(4)e0215122 PMID: 30995271
Kregel S, Malik R, Asangani IA, Wilder-Romans K, Rajendiran T, Xiao L, Vo JN, Soni T, Cieslik M, Fernandez-Salas E, Zhou B, Cao X, Speers C, Wang S, Chinnaiyan AM.2019Functional and Mechanistic interrogation of BET bromodomain degraders for the treatment of metastatic castration-resistant prostate cancer. Clin. Cancer Res. 2019, 25(13):4038-4048. PMID:30918020
Mitchell DC, Menon A, Garner AL.2019Chemoproteomic profiling uncovers CDK4-mediated phosphorylation of the translational suppressor 4E-BP1. Cell Chem. Biol. 2019, 26(7):980-990. PMID: 31056462
Maitra D, Carter EL, Richardson R, Rittie L, Basrur V, Zhang H, Nesvizhskii AI, Osawa Y, Worlf MW, Ragsdale SW, Lehnert N, Hermann H, Omary MB.2019Oxygen and conformation dependent protein oxidation and aggregation by porphyrins in hepatocytes and light-exposed cells. Cell Mol. Gastroenterol. Hepatol. 2019. PMID:31173894
Park MJ, D'Alecy LG, Anderson MA, Basrur V, Feng Y, Brady GF, Kim DI, Wu J, Nesvizhskii AI, Lahann J, Lukacs NW, Fontana RJ, Omary MB.2019Constitutive release of CPS1 in bile and its role as a protective cytokine during acute liver injury. Proc. Natl. Acad. Sci. USA, 2019, 116(18):9125-9134. PMID: 30979808
Sinicropi-Yao SL, Amann JM, Lopez DLY, Cerciello F, Coombes KR, Carbone DP.2019Co-expression analysis reveals mechanisms underlying the varied roles of NOTCH1 in NSCLC. J. Thorac. Oncol. 2019, 12(2):223-236. PMID: 30408569
Korwar AM, Shay AE, Basrur V, Conlon K, Prabhu KS.2019Seleniproteome identification in inflamed murine primary bone marrow-derived macrophages by nano-LC Orbitrap Fusion Tribrid mass spectrometry. J. Am. Soc. Mass Spectrom. 2019, 30(7):1276-1283.
Matthew AV, Li L, Byun J, Guo Y, Michailidis G, Jaiswal M, Chen YE, Pop-Busui R, Pennathur S.2018Therapeutic lifestyle changes improve HDL function by inhibiting myeloperoxidase-mediated oxidation in patients with metabolic syndrome. Diabetes Care, 2018, 41(11):2431-2437
Yang S, Shergalis A, Lu D, Kyani A, Lu Z, Ljungman M, Neamati N.2018Design, Synthesis, and Biological Evaluation of Novel Allosteric Protein Disulfide Isomerase Inhibitors. J. Med. Chem. 2019, 62(7):3447-3474.
Zhang H, Yokom AL, Cheng S, Su M, Hollenberg PF, Southworth DR, Osawa Y.2018The full-length cytochrome P450 enzyme CYP102A1 dimerizes at its reductase domains and has flexible heme domains for efficient catalysis. J. Biol. Chem. 2018, 293(20):7727-7736.
Won SJ, Martin BR.2018Temporal profiling establishes a dynamic S-palmitoylation cycle. ACS Chem. Biol. 2018, 13(6):1560-1568
Yu L, Jearawiriyapaisarn N, Lee MP, Hosoya T, Wu Q, Myers G, Lim KC, Kurita R, Nakamura Y, Vojtek AB, Rual JF, Engel JD.2018BAP1 regulation of the key adaptor protein NCoR1 is critical for g-globin gene repression. Genes Dev. 2018, 32(23-24):1537-1549
Singh AK, Khare P, Obaid A, Conlon KP, Basrur V, DePinho RA, Venuprasad K.2018SUMOylation of ROR-gt inhibits IL-17 expression and inflammation via HDAC2. Nat. Commun. 2018, 9(1):4515
Tank EM, Figueroa-Romero C, Hinder LM, Bedi K, Archbold HC, Li X, Weskamp K, Safren N, Paez-Colasante X, Pacut C, Thumma S, Paulsen MT, Guo K, Hur J, Ljungman M, Feldman EL, Barmada SJ.2018Abnormal RNA stability in amyotrophic lateral sclerosis. Nat. Commun. 2018, 9(1):2845
Anwar T, Arellano-Garcia C, Ropa J, Chen YC, Kim HS, Yoon E, Grigsby S, Basrur V, Nesvizhskii AI, Muntean A, Gonzalez ME, Kidwell KM, Nikolovska-Coleska Z, Kleer CG.2018p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasis. Nat. Commun. 2018, 9(1):2801
Glazier AA, Hafeez N, Mellacheruvu D, Basrur V, Nesvizhskii AI, Lee LM, Shao H, Tang V, Yob JM, Gestwicki JE, Helms AS, Day SM.2018HSC70 is a chaperone for wild-type and mutant cardiac myosin binding protein C. JCI Insight 2018, 3(11).
Ropa J, Saha N, Chen Z, Serio J, Chen W, Mellacheruvu D, Zhao L, Basrur V, Nesvizhskii AI, Muntean AG.2018PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia. Oncotarget 2018, 9(31):22123-22136
Cho CS, Park HW, Ho A, Semple IA, Kim B, Jang I, Park H, Reilly S, Saltiel AR, Lee JH.2018Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1-mediated p62/sequestosome 1 phosphorylation. Hepatology 2018, 68(4):1331-1346. PMID: 29251796
McClintock SD, Colacino JA, Attili D, Dame MK, Richter A, Reddy A, Basrur V, Rizvi AH, Turgeon DK, Varani J, Aslam MN.2018Calcium-induced differentiation of human colon adenomas in colonoid culture: Calcium alone versus calcium with additional trace elements. Cancer Prev. Res (Phila) 2018, 11(7):413-428.
Frattini V, Pagnotta SM, Tala, Fan JJ, Russo MV, Lee SB, Garofano L, Zhang J, Shi P, Lewis G, Sanson H, Frederck V, Castano AM, Cerulo L, Rolland DCM, Mall R, Mokhtari K, Elenitoba-Johnson KSJ, Sanson M, Huang X, Ceccarelli M, Lasorella A, Iavarone A.2018A metabolic function of FGFR3-TACC3 gene fusions in cancer. Nature 2018, 553(7687):222-227.
Wang G, Mathew AV, Yu H, Li L, He L, Gao W, Liu X, Gua Y, Byun J, Zhang J, Chen YE, Pennathur S.2018Myeloperoxidase mediated HDL oxidation and HDL proteome changes do not contribute to dysfunctional HDL in Chinese subjects with coronary artery disease. PLos One 2018, 13(3):e0193782.
Nyati S, Chaudhry N, Chatur A, Gregg BS, Kimmel L, Khare D, Basrur V, Ray D, Rehemtulla A.2018A novel reporter for real-time, quantitative imaging of AKT-directed K63-poly-ubiquitination in living cells. Oncotarget 2018, 9(13):11083-11099.
Hawkins AG, Basrur V, da Veiga Leprevost F, Pedersen E, Sperring C, Nesvizhskii AI, Lawlor ER.2018The Ewing sarcoma secretome and its response to activation of Wnt/beta-catenin signaling. Mol. Cell Proteomics 2018, 17(5):901-912.
Paul J, Singh AK, Kathania M, Elviche TL, Zeng M, Basrur V, Theiss AL, Venuprasak K.2018IL-17-driven intestinal fibrosis is inhibited by Itch-mediated ubiquitination of HIC-5. Mucosal. Immunol. 2018, 11(2):427-436
Awasthi A, Rolland DCM, Ayello J, van de Ven C, Basrur V, Conlon K, Fermin D, Barth MJ, Klein C, Elenitoba-Johnson KSJ, Lim MS, Cairo MS.2017A comparative global phosphoproteomic analysis of obinutuzumab (GA101) versus rituximab (RTX) against RTX sensitive and resistant Burkitt lymphoma (BL) demonstrates differential phosphorylation of signaling pathway proteins after treatment. Oncotarget 2017, 8(69):113895-113909.
Xue x, Bredell BX, Anderson ER, Martin A, Mays C, Nagao-Kitamoto H, Huang S, Gyorffy B, Greenson JK, Hardiman K, Spence JR, Kamada N, Shah YM.2017Qunatitative proteomics identifies STEAP4 as a critical regulator or mitochondrial dysfunction linking inflammation and colon cancer. Proc. Natl. Acad. Sci. USA, 2017, 114(45)E9608-E9617.
Xu T, Park SS, Giaimo BD, Hall D, Ferrante F, Ho DM, Hori K, Anhezini L, Ertl I, Bartkuhn M, Zhang H, Milon E, Ha K, Conlon KP, Kuick R, Govindarajoo B, Zhang Y, Sun Y, Dou Y, Basrur V, Elenitoba-Johnson KS, Nesvizhskii AI, Ceron J, Lee CY, Borggrefe T, Kovall RA, Rual JF.2017RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demthylase KDM1A/LSD1. EMBO J. 2017, 36(21):3232-3249.
Brady GF, Kwan R, Ulintz PJ, Nguyen P, Bassirian S, Basrur V, Nesvizhskii AI, Loomba R, Omary MB.2017Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease. Hepatology 2017, 67(5):3232-3249.
Krishnamurthy PM, Shukla S, Ray P, Mehra R, Nyati MK, Lawrence TS, Ray D.2017Involvement of p38-bTrCP-Tristetraprolin-TNFa axis in radiation pneumonitis. Oncotarget, 2017, 8(29):47767-79.
Rolland DCM, Basrur V, Jeon YK, McNeil-Schwalm C, Fermin D, Conlon KP, Zhou Y, Nq SY, Tsou CC, Brown NA, Thomas DG, Bailey NG, Omenn GS, Nesvizhskii AI, Root DE, Weinstock DM, Faryabi RB, Lim MS, Elenitoba-johnson KSJ.2017Functional proteogenomics reveals biomarkers and therapeutic targets in lymphomas. Proc. Natl. Acad. Sci. USA 2017, 114(25):6581-6586.
Ho KK, Lee JW, Durand G, Majumder S, Liu AP.2017Protein aggregation with poly(vinyl) alcohol surfactant reduces double emulsion-encapsulated mammalian cell-free expression. PLoS One 2017, 12(3):e0174689.
Hwang SR, Murga-Zamalloa C, Brown N, Basappa J, McDonnell SR, Mendoza-Reinoso V, Basrur V, Wilcox R, Elenitoba-Johnson K, Lim MS.2017Pyrimidine tract-binding protein 1 mediates pyruvate kinase M2-dependent phosphorylation of signal transducer and activator of transcription 3 and oncognesis in anaplastic large cell lymphoma. Lab. Invest. 2017, 97(8):962-970.
Sakamoto K, Kim YF, Hara H, Kamada N, Caballero-Flores G, Tolosano E, Soares MP, Puente JL, Inohara N, Nunez G.2017IL-22 controls iron-dependent nutritional immunity against sytemic bacterial infections. Sci. Immunol. 2017
Bai L, Zhou B, Yang CY, Ji J, McEachern D, Przybranowski S, Jiang H, Hu J, Xu F, Zhao Y, Liu L, Fernandez-Salas E, Zu J, Doy Y, Wen B, Sun D, Meagher JL, Stuckey J, Hayes DF, Li S, Ellis MJ, Wang S.2017Targeted Degradation of BET proteins in triple-negative breast cancer. Cancer Res. 2017, 77(9):2476-2487.
Murga-Zamalloa CA, Mendoza-Reinoso v, Sahasrabuddhe AA, Rolland D, Hwang SR, McDonnell SR, Sciallis AP, Wilcox RA, Basrur V, Elenitoba-Johnson K, Lim MS.2017NPM-ALK phosphorylates WASP Y102 and contributes to oncogenesis of anaplastic large cell lymphoma. Oncogene, 2017, 36(15):2085-2094.
Bagchi P, Inoue T, Tsai B.2016EMC1-dependent stabilization drives membrane penetration of a partially destabilized non-enveloped virus. Elife 2016.
Xue X, Ramakrishnan SK, Weisz K, Triner D, Xie L, Attili D, Pant A, Gyorffy B, Zhan M, Carter-Su C, Hardiman KM, Wang TD, Dame MK, Varani J, Brenner D, Fearon ER, Shah YM.2016Iron uptake via DMT1 integrates cell cycle with JAK-STAT3 signaling to promote colorectal tumorigenesis. Cell Metab. 2016, 24(3):447-61.
He Y, Zeng MY, Yang D, Motro B, Nunez G.2016NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux. Nature, 2016, 530(7590):354-7.
Wang B, Merillat SA, Vincent M, Huber AK, Basrur V, Mangelberger D, Zeng L, Elenitoba-Johnson K, Miller RA, Irani DN, Dlugosz AA, Schnell S, Scaglione KM, Paulson HL.2016Loss of the ubiquitin-conjugating enzyme Ube2W results in susceptibility to early postnatal lethality and defects in skin, immune and male reproductive systems. J. Biol. Chem. 2016, 291(6):3030-42.
Nam SJ, Kim S, Kim JE, Lim MS, Elenitoba-Johnson KS, Kim CW, Jeon YK.2016Aberrant expression of napsin A in a subset of malignant lymphomas. Histol. Histopathol. 2016, 31(2):213-21.
Kathania M, Zeng M, Yadav VN, Moghaddam SJ, Yang B, Venuprasad K.2015Ndfip1 regulates itch ligase activity and airway inflammation via UbcH7. J. Immunol. 2015, 194(5):2160-7.
Goldstein RL, Yang SN, Taldone T, Chang B, Gerecitano J, Elenitoba-Johnson K, Shaknovich R, Tam W, Leonard JP, Chiosis G, Cerchietti L, Melnick A.2015Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma. J. Clin. Invest. 2015, 125(12):4559-71.
Pinnel N, Yan R, Cho HJ, Keeley T, Murai MJ, Liu Y, Alarcon AS, Qin J, Wang Q, Kuick R, Elenitoba-Johnson KS, Maillard I, Samuelson LC, Cierpicki T, Chiang MY.2015The PIAS-like coactivator Zmiz1 is a direct and selective cofactor of Notch1 in T cell development and leukemia. Immunity 2015, 43(5):870-83.
Zhang H, Ramakrishnan SK, Triner D, Centofanti B, Maitra D, Gyorffy B, Sebolt-Leopold JS, Dame MK, Varani J, Brenner DE, Fearon ER, Omary MB, Shah YM.2015Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1. Sci. Signal. 2015, 8(397):ra98
Maitra D, Elenbaas JS, Whitesall SE, Basrur V, D'Alecy LG, Omary MB.2015Ambient light promotes selective subcellular proteotoxicity after endogenous and exogenous porphyrinogenic stress. J. Biol. Chem. 2015, 290(39):23711-24
Theivanthiran B, Kathania M, Zeng M, Anguiano E, Basrur V, Vanderfriff T, Pascual V, Wei WZ, Massoumi R, Venuprasad K.2015The E3 ubiquitin ligase Itch inhibits p38alpha signaling and skin inflammation through the ubiquitylation of Tab1. Sci. Signal. 2015, 8(365):ra22
Nie Z, Du MQ, McAllister-Lucas LM, Lucas PC, Bailey NG, Hogaboam CM, Lim MS, Elenitoba-Johnson KS.2015Conversion of the LIMA1 tumour suppressor into an oncogenic LMO-like protein by API2-MALT1 in MALT lymphoma. Nat. Commun. 2015, 6:5908
El-Mallawany NK, Day N, Ayello J, Van de Ven C, Conlon K, Fermin D, Basrur V, Elenitoba-Johnson K, Lim M, Cairo MS.2015Differential proteomic analysis of endemic and sporadic Epstein-Barr virus-positive and negative Burkitt lymphoma. Eur. J. Cancer 2015, 51(1):92-100
Vittal V, Shi L, Wenzel DM, Scaglione KM, Duncan ED, Basrur V, Elenitoba-Johnson KS, Baker D, Paulson HL, Brzovic PS, Klevit RE.2015Intrinsic disorder drives N-terminal ubiquitination by Ube2W. Nat. Chem. Biol. 2015, 11(1):83-89
Chung FZ, Sahasrabuddhe AA, Ma K, Chen X, Basrur V, Lim MS, Elenitoba-Johnson KS.2014Fbxo45 inhibits calcium-sensitive proteolysis of N-cadherin and promotes neuronal differentiation. J. Biol. Chem. 2014, 289(41):28448-59
Banerjee R, Russo N, Liu M, Basrur V, Bellile E, Palanisamy N, Scanlon CS, van Tubergen E, Inglehart RC, Metwally T, Mani RS, Yocum A, Nyati MK, Castilho RM, Varambally S, Chinnaiyan AM, D'Silva NJ.2014TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer. Nat. Commun. 2014, 5:4527.
Chen X, Sahasrabuddhe AA, Szankasi P, Chung F, Basrur V, Rangnekar VM, Pagano M, Lim MS, Elenitoba-Johnson KS.2014Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survival. Cell Death Differ. 2014, 21(10):1535-45.
He Y, Varadarajan S, Munoz-Planillo R, Burberry A, Nakamura Y, Nunez G.20143,4-methylenedioxy-_-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome. J. Biol. Chem. 2014, 289(2):1142-50.
Rolland D, Basrur V, Conlon K, Wolfe T, Fermin D, Nesvizhskii AI, Lim MS, Elenitoba-Johnson KS.2014Global phosphoproteomic profiling reveals distinct signatures in B-cell non-hodgkin lymphomas. Am. J. Pathol. 2014, 184(5):1331-42.
Shukla S, Allam US, Ahsan A, Chen G, Krishnamurthy PM, Marsh K, Rumschlag M, Shankar S, Whitehead C, Schipper M, Basrur V, Sourthworth DR, Chinnaiyan AM, Rehemtulla A, Beer DG, Lawrence TS, Nyati MK, Ray D2014KRAS protein stability is regulated through SMURF2:UBCH5 complex-mediated b-TrCP1 degradation. Neoplasia 2014, 16(2):115.
Sueyoshi R, Woods Ignatoski KM, Okawada M, Teitelbaum DH.2014Distraction-induced intestinal growth: The role of mechanotransduction mechanisms in a mouse model of short bowel syndrome. Tissue Eng. Part A. 2014, 20(3-4):830-41
Yan Y, Shapiro AP, Haller S, Katragadda V, Liu L, Tian J, Basrur V, Malhotra D, Xie ZJ, Abraham NG, Shapiro JI, Liu J.2013Involvement of ractive oxygen species in a feed-forward mechanisms of Na/K-ATPase-mediated signaling transduction. J. Biol. Chem. 2013, 288(47):34249-58.
Nakamura Y, Oscherwitz J, Cease KB, Chan SM, Munoz-Planillo R, Hasegawa M, Villaruz AE, Cheung GY, McGavin MJ, Travers JB, Otto M, Inohara N, Nunez G.2013Staphylococcus d-toxin induces allergic skin disease by activating mast cells. Nature 2013, 503(7476):397-401.
Paul B, Das D, Ellington B, Marsh EN.2013Probing the mechanism of cyanobacterial aldehyde decarbonylase using a cyclopropyl aldehyde. J. Am. Chem. Soc. 2013, 135(14):5234-7
Mower J, Uhm M, Reilly SM, Simon J, Leto D, Chiang SH, Chang L, Saltiel AR.2013Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKe and TBK1. eLife 2013, 2:e01119.
Conlon KP, Basrur V, Rolland D, Wolfe T, Nesvizhskii AI, Maccoss MJ, Lim MS, Elenitoba-Johnson KS.2013Fusion peptides from oncogenic chimeric proteins as specific biomarkers of cancer. Mol. Cell Proteomics 2013, 12(10):2714-23.
McDonnell RPS, Hwang SR, Rolland D, Murga-Zamalloa C, Basrur v, Conlon KP, Fermin D, Wolfe T, Rasking A, Ruan C, Jiang J-K, Thomas CJ, Hogaboam CM, Burant CF, Elenitoba-Johnson KSJ, Lim MS.2013Integrated phosphoproteomic and metabolomics profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma. Blood 2013, 122(6): 959-68.
Chiruvella KK, Liang Z, Birkeland SR, Basrur V, Wilson TE.2013Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic activity. PLOS Genetics. 2013,9(6):e1003599.
Scaglione KM, Basrur V, Ashraf NS, Konen JR, Elenitoba-Johnson KS, Todi SV, Paulson HL.2013The ubiquitin conjugating enzyme (E2) Ube2w ubiquitinates the N-terminus of substrates. J Biol Chem. 2013, 288(26):18784-8
Todd PK, Oh SY, Krans A, He F, Sellier C, Frazer M, Renoux AJ, Chen KC, Scaglione KM, Basrur V, Elenitoba-Johnson K, Vonsattel JP, Louis ED, Sutton MA, Taylor JP, Mills RE, Charlet-Berguerand N, Paulson HL.2013CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome. Neuron. 2013, 78(3):440-55.
Ma T, Chen Y, Zhang F, Yang CY, Wang S, Yu X.2013RNF111-dependent neddylation activates DNA damage-induced ubiquitination. Mol Cell. 2013, 49(5):897-907.
Ling S, Cline EN, Hauq TS, Fox DA, Holoshitz J.2013Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling. Arthritis Reheum. 2013, 65(3):618-25.
Min DJ, Ezponda T, Kim MK, Will CM, Martinez-Garcia E, Popovic R, Basrur V, Elenitoba-Johnson KS, Licht JD.2013MMSET stimulates myeloma cell growth through microRNA-mediated modulation of c-MYC. Leukemia. 2013, 27(3):686-94. doi: 10.1038/leu.2012.269.
Miyata Y, Rauch JN, Jinwal UK, Thompson AD, Srinivasan S, Dickey CA, Gestwicki JE.2012Cysteine reactivity distinguishes redox sensing by the heat-inducible and constitutive forms of heat shock protein 70. Chem Biol. 2012, 19(11):1391-9.
Thompson AD, Scaglione KM, Prensner J, Gillies AT, Chinnaiyan A, Paulson HL, Jinwal UK, Dickey CA, Gestwicki JE.2012Analysis of the tau-associated proteome reveals that exchange of Hsp70 for Hsp90 is involved in tau degradation. ACS Chem Biol. 2012, 7(10):1677-86.
Busino L, Millman SE, Scotto L, Kyratsous CA, Basrur V, O'Connor O, Hoffmann A, Elenitoba-Johnson KS, Pagano M.2012Fbxw7_- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma. Nat Cell Biol. 2012,14(4):375-85.
Wang J, Muntean AG, Hess JL.2012ECSASB2 mediates MLL degration during hematopoietic differentiation. Blood. 2012,119(5):1151-61.
Popovych N, Brender JR, Soong R, Vivekanandan S, Hartman K, Basrur V, Macdonald PM, Ramamoorthy A.2012Site specific interaction of the polyphenol EGCG with the SEVI amyloid precursor peptide PAP(248-286). J Phys Chem B. 2012, 116(11):3650-8.
Lin Z, Lo A, Simeone DM, Ruffin MT, Lubman DM.2012An N-glycosylation analysis of human alpha-2-macroglobulin using an integrated approach. J Proteomics Bioinform. 2012, 5:127-34.
McDonnell SR, Hwang SR, Basrur V, Conlon KP, Fermin D, Wey E, Murga-Zamalloa C, Zeng Z, Zu Y, Elenitoba-Johnson KS, Lim MS.2012NPM-ALK signals through glycogen synthase kinase 3_ to promote oncogenesis. Oncogene. 2012, 31(32):3733-40.
Huang Y, Sitwala K, Bronstein J, Sanders D, Dandekar M, Collins C, Robertson G, MacDonald J, Cezard T, Bilenky M, Thissen N, Zhao Y, Zeng T, Hirst M, Hero A, Jones S, Hess JL.2012Identification and characterization of Hoxa9 binding sites in hematopoietic cells. Blood, 2012, 119(2):388
Vivekanandan-Giri A, Slocum JL, Buller CL, Basrur V, Ju W, Pop-Busui R, Lubman DM, Kretzler M, Pennathur S.2011Urine glycoprotein profile reveals novel markers for chronic kidney disease. Int J Proteomics. 2011, 2011:214715.
Walter GM, Smith MC, WisŽn S, Basrur V, Elenitoba-Johnson KS, Duennwald ML, Kumar A, Gestwicki JE.2011Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probes. J Biol Chem. 2011, 286(47):40486-93.
Biswas D, Milne TA, Basrur V, Kim J, Elenitoba-Johnson KS, Allis CD, Roeder RG.2011Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes. Proc Natl Acad Sci U S A. 2011,108(38):15751-6.
Brenner JC, Ateeq B, Li Y, Yocum AK, Cao Q, Asangani IA, Patel S, Wang X, Liang H, Yu J, Palanisamy N, Siddiqui J, Yan W, Cao X, Mehra R, Sabolch A, Basrur V, Lonigro RJ, Yang J, Tomlins SA, Maher CA, Elenitoba-Johnson KS, Hussain M, Navone NM, Pienta KJ, Varambally S, Feng FY, Chinnaiyan AM.2011Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer. Cancer Cell. 2011,19(5):664-78.
Fermin D, Basrur V, Yocum AK, Nesvizhskii AI.2011Abacus: a computational tool for extracting and pre-processing spectral count data for label-free quantitative proteomic analysis. Proteomics. 2011, 11(7):1340-5.
Monroe SC, Jo SY, Sanders DS, Basrur V, Elenitoba-Johnson KS, Slany RK, Hess JL.2011MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia. Exp Hematol. 2011, 39(1):77-86.
Cao F, Chen Y, Cierpicki T, Liu Y, Basrur V, Lei M, Dou Y.2010An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain. PLoS One. 2010, 5(11):e14102
Todi SV, Scaglione KM, Blount JR, Basrur V, Conlon KP, Pastore A, Elenitoba-Johnson K, Paulson HL.2010Activity and cellular functions of the deubiquitinating enzyme and polyglutamine disease protein ataxin-3 are regulated by ubiquitination at lysine 117. J Biol Chem. 2010, 285(50):39303-13.
Maine GN, Li H, Zaidi IW, Basrur V, Elenitoba-Johnson KS, Burstein E.2010A bimolecular affinity purification method under denaturing conditions for rapid isolation of a ubiquitinated protein for mass spectrometry analysis. Nat Protoc. 2010, 5(8):1447-59.
Muntean AG, Tan J, Sitwala K, Huang Y, Bronstein J, Connelly JA, Basrur V, Elenitoba-Johnson KS, Hess JL.2010The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis. Cancer Cell. 2010, 17(6):609-21.
Milne TA, Kim J, Wang GG, Stadler SC, Basrur V, Whitcomb SJ, Wang Z, Ruthenburg AJ, Elenitoba-Johnson KS, Roeder RG, Allis CD.2010Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis. Mol Cell. 2010, 38(6):853-63.
Brady GF, Galb‡n S, Liu X, Basrur V, Gitlin JD, Elenitoba-Johnson KS, Wilson TE, Duckett CS.2010Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination. Mol Cell Biol. 2010, 30(8):1923-36.
Frescas D, Guardavaccaro D, Kuchay SM, Kato H, Poleshko A, Basrur V, Elenitoba-Johnson KS, Katz RA, Pagano M.2008KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state. Cell Cycle. 2008, 7(22):3539-47.

Acknowledgment of Contributions

Publications containing data generated by the Proteomics Resource Facility (PRF) should include an acknowledgement of the PRF or include members as coauthors. The PRF needs these acknowledgements and authorship to help demonstrate our contributions to the research community. This in turn helps secure future funding to maintain a robust Core facility and provide professional development of its staff. The Association of Biomolecular Resource Facilities (ABRF) has published a guideline to use when considering whether or not to include core laboratory members on publications.

 

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