Publications Supported by the Transgenic Core

AuthorsYearPublication
Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FSJ, Camper SA.
J Clin Invest.
2020Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. 2020 May 26:136745. doi: 10.1172/JCI136745. Online ahead of print.
PMID: 32453714
Su RC, Warner EA, Breidenbach JD, Lad A, Blomquist TM, Kleinhenz AL, Modyanov N, Malhotra D, Kennedy DJ, Haller ST.2020CD40 Receptor Knockout Protects against Microcystin-LR (MC-LR) Prolongation and Exacerbation of Dextran Sulfate Sodium (DSS)-Induced Colitis.
Biomedicines. 2020 Jun 2;8(6):E149. doi: 10.3390/biomedicines8060149.
PMID: 32498446
Flak JN, Goforth PB, Dell'Orco J, Sabatini PV, Li C, Bozadjieva N, Sorensen M, Valenta A, Rupp A, Affinati AH, Cras-Méneur C, Ansari A, Sacksner J, Kodur N, Sandoval DA, Kennedy RT, Olson DP, Myers MG Jr.2020Ventromedial hypothalamic nucleus neuronal subset regulates blood glucose independently of insulin.
J Clin Invest. 2020 Jun 1;130(6):2943-2952. doi: 10.1172/JCI134135.
PMID: 32134398
Zhu L, Tang Y, Li XY, Keller ET, Yang J, Cho JS, Feinberg TY, Weiss SJ.2020Osteoclast-mediated bone resorption is controlled by a compensatory network of secreted and membrane-tethered metalloproteinases.
Sci Transl Med. 2020 Feb 5;12(529):eaaw6143. doi: 10.1126/scitranslmed.aaw6143.
PMID: 32024800
Lovat F, Nigita G, Distefano R, Nakamura T, Gasparini P, Tomasello L, Fadda P, Ibrahimova N, Catricalà S, Palamarchuk A, Caligiuri MA, Gallì A, Malcovati L, Minden MD, Croce CM.2020Combined loss of function of two different loci of miR-15/16 drives the pathogenesis of acute myeloid leukemia.
Proc Natl Acad Sci U S A. 2020 May 18:202003597. doi: 10.1073/pnas.2003597117.
PMID: 32424097
Song JY, Pineault KM, Dones JM, Raines RT, Wellik DM.2020Hox genes maintain critical roles in the adult skeleton. Proc Natl Acad Sci U S A. 2020 Mar 13. pii: 201920860. doi: 10.1073/pnas.1920860117. [Epub ahead of print]
PMID: 32170021
El-Zaatari M , Bishu S, Zhang M, Grasberger H, Hou G, Haley H, Humphries B, Syu LJ, Dlugosz AA, Luker K, Luker GD, Eaton K, Kamada N, Cascalho M, Kao JY.2020Aim2-mediated/IFN-β-independent regulation of gastric metaplastic lesions via CD8+ T cells. JCI Insight. 2020 Mar 12;5(5). pii: 94035. doi: 10.1172/jci.insight.94035. PMID: 32053518
Matsushita Y, Nagata M, Kozloff KM, Welch JD, Mizuhashi K, Tokavanich N, Hallett SA, Link DC, Nagasawa T, Ono W, Ono N.2020A Wnt-mediated transformation of the bone marrow stromal cell identity orchestratesskeletal regeneration. Nat Commun.11:332. PMID: 31949165
Yu H, Thompson Z, Kiran S, Jones GL, Mundada L; Surbhi , Rubinstein M, Low MJ.2020Expression of a hypomorphic Pomc allele alters leptin dynamics during late pregnancy. J Endocrinol. 2020 Apr;245(1):115-127. doi: 10.1530/JOE-19-0576.
PMID: 32027603
Ding L, Li Q, Chakrabarti J, Munoz A, Faure-Kumar E, Ocadiz-Ruiz R, Razumilava N, Zhang G, Hayes MH, Sontz RA, Mendoza ZE, Mahurkar S, Greenson JK, Perez-Perez G, Hanh NTH, Zavros Y, Samuelson LC, Iliopoulos D, Merchant JL.2020MiR130b from Schlafen4+ MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer. Gut. 2020 Jan 24. pii: gutjnl-2019-318817. doi: 10.1136/gutjnl-2019-318817. [Epub ahead of print] PMID: 31980446
Zhu L, Tang Y, Li XY, Keller ET, Yang J, Cho JS, Feinberg TY2020Osteoclast-mediated bone resorption is controlled by a compensatory network of secreted and membrane-tethered metalloproteinases. Sci Transl Med. 2020 Feb 5;12(529). pii: eaaw6143. doi: 10.1126/scitranslmed.aaw6143. PMID: 32024800
Demireva EY, Xie H, Flood ED, Thompson JM, Seitz BM, Watts SW.2019Creation of the 5-hydroxytryptamine receptor 7 knockout rat as a tool for cardiovascular research. Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.
PMID: 31125290
Hu Y, Smith DE.2019In Silico Prediction of the Absorption and Disposition of Cefadroxil in Humans using an Intestinal Permeability Method Scaled from Humanized PepT1 Mice. Drug Metab Dispos. 2019 Mar;47(3):173-183. doi: 10.1124/dmd.118.084236. Epub 2018 Dec 28. PMID: 30593545
Keeley TM, Horita N, Samuelson LC.2019Tamoxifen-Induced Gastric Injury: Effects of Dose and Method of Administration. Cell Mol Gastroenterol Hepatol. 2019;8(3):365-367. doi: 10.1016/j.jcmgh.2019.06.007. Epub 2019 Jun 21. No abstract available.
PMID: 31233898
Yuan Y, O'Malley HA, Smaldino MA, Bouza AA, Hull JM, Isom LL.2019Delayed maturation of GABAergic signaling in the Scn1a and Scn1b mouse models of Dravet Syndrome. Sci Rep. 2019 Apr 17;9(1):6210. doi: 10.1038/s41598-019-42191-0. PMID: 30996233
O'Malley HA, Hull JM, Clawson BC, Chen C, Owens-Fiestan G, Jameson MB, Aton SJ, Parent JM, Isom LL.2019Scn1b deletion in adult mice results in seizures and SUDEP. Ann Clin Transl Neurol. 2019 May 8;6(6):1121-1126. doi: 10.1002/acn3.785. eCollection 2019 Jun. PMID: 31211177
Bashir B, Merlino DJ, Rappaport JA, Gnass E, Palazzo JP, Feng Y, Fearon ER, Snook AE, Waldman SA.2019Silencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated, and MSI colorectal neoplasia. Hum Pathol. 2019 May;87:103-114. doi: 10.1016/j.humpath.2018.11.032. Epub 2019 Feb 2. PMID: 30716341
Tang J, Feng Y, Kuick R, Green M, Green M, Sakamoto N, Kurosu Y, Lin J, Cho KR, Fearon ER.2019Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis. Lab Invest. 2019 Oct;99(10):1454-1469. doi: 10.1038/s41374-019-0269-y. Epub 2019 May 31. PMID: 31148594
McCool KW, Freeman ZT, Zhai Y, Wu R, Hu K, Liu CJ, Tomlins SA, Fearon ER, Magnuson B, Kuick R, Cho KR.2019Murine Oviductal High-Grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles, and Immune Microenvironment of Their Human Counterparts. Cancer Res. 2020 Feb 15;80(4):877-889. doi: 10.1158/0008-5472.CAN-19-2558. Epub 2019 Dec 5. PMID: 31806642
Billi AC, Gharaee-Kermani M, Fullmer J, Tsoi LC, Hill BD, Gruszka D, Ludwig J, Xing X, Estadt S, Wolf SJ, Rizvi SM, Berthier CC, Hodgin JB, Beamer MA, Sarkar MK, Liang Y, Uppala R, Shao S, Zeng C, Harms PW, Verhaegen ME, Voorhees JJ, Wen F, Ward NL, Dlugosz AA, Kahlenberg JM, Gudjonsson JE.2019The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity. JCI Insight. 2019 Apr 18;4(8). pii: 127291. doi: 10.1172/jci.insight.127291. eCollection 2019 Apr 18. PMID: 30996136
Kimball AS, Davis FM, denDekker A, Joshi AD, Schaller MA, Bermick J, Xing X, Burant CF, Obi AT, Nysz D, Robinson S, Allen R, Lukacs NW, Henke PK, Gudjonsson JE, Moore BB, Kunkel SL, Gallagher KA.2019The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair. Immunity. 2019 Aug 20;51(2):258-271.e5. doi: 10.1016/j.immuni.2019.06.015. Epub 2019 Jul 23. PMID: 31350176
Bunton-Stasyshyn RKA, Wagnon JL, Wengert ER, Barker BS, Faulkner A, Wagley PK, Bhatia K, Jones JM, Maniaci MR, Parent JM, Goodkin HP, Patel MK, Meisler MH. 2019Prominent role of forebrain excitatory neurons in SCN8A encephalopathy. Brain. 2019 Feb 1;142(2):362-375. PMID: 30601941
Engelke MF, Waas B, Kearns SE, Suber A, Boss A, Allen BL, Verhey KJ. 20192019. Acute Inhibition of Heterotrimeric Kinesin-2 Function Reveals Mechanisms of IntraflagellarTransport in Mammalian Cilia. Curr Biol. 29:1137-1148. PMID: 30905605
Fleming JT, Brignola E, Chen L, Guo Y, Zhao S, Wang Q, Li B, Correa H, Ermilov AN, Dlugosz AA, Chiang C.2019Insight into the Etiology of Undifferentiated Soft Tissue Sarcomas from a Novel Mouse Model. Mol Cancer Res. 2019 Jan 25. [Epub ahead of print]. PMID: 30683671
Flores A, Argetsinger LS, Stadler LKJ, Malaga AE, Vander PB, DeSantis LC, Joe RM, Cline JM, Keogh JM, Henning E, Barroso I, Mendes de Oliveira E, Chandrashekar G, Clutter ES, Hu Y, Stuckey J, Farooqi IS, Myers MG Jr, Carter-Su C.2019Crucial Role of the SH2B1 PH Domain for the Control of Energy Balance. Diabetes. 2019 Aug 22. pii: db190608. doi: 10.2337/db19-0608. [Epub ahead of print] PMID: 31439647
McCabe IC, Fedorko A, Myers MG Jr, Leinninger G, Scheller E, McCabe LR.2019Novel leptin receptor signaling mutants identify location and sex-dependent modulation of bone density, adiposity, and growth. J Cell Biochem. 2019 Mar;120(3):4398-4408. PMID: 30269370
Pan W, Allison MB, Sabatini P, Rupp A, Adams J, Patterson C, Jones JC, Olson DP, Myers MG Jr.2019Transcriptional and physiological roles for STAT proteins in leptin action. Mol Metab. 2019 Jan 24. pii: S2212-8778(18)31242-0. PMID: 30718218
Pei H, Patterson CM, Sutton AK, Burnett KH, Myers MG Jr, Olson DP.2019Lateral Hypothalamic Mc3R-Expressing Neurons Modulate Locomotor Activity, Energy Expenditure, and Adiposity in Male Mice. Endocrinology. 2019 Feb 1;160(2):343-358. PMID: 30541071
Pettibone JR, Yu JY, Derman RC, Faust TW, Hughes ED, Filipiak WE, Saunders TL, Ferrario CR, Berke JD.2019Knock-in rat lines with Cre recombinase at the dopamine D1 and adenosine 2a receptor loci. eNeuro. 2019 Aug 26. pii: ENEURO.0163-19.2019. doi: 10.1523/ENEURO.0163-19.2019. [Epub ahead of print] PMID: 31451604
Sun Y, Oravecz-Wilson K, Bridges S, McEachin R, Wu J, Kim SH, Taylor A, Zajac C, Fujiwara H, Peltier DC, Saunders T, Reddy P.2019miR-142 controls metabolic reprogramming that regulates dendritic cell activation. J Clin Invest. 130. pii: 123839. PMID: 30958798
Wang S, Walton KD, Gumucio DL.2019Signals and forces shaping organogenesis of the small intestine. Curr Top Dev Biol. 2019;132:31-65. PMID: 30797512
Yin Y, Xie CM, Li H, Tan M, Chen G, Schiff R, Xiong X, Sun Y.2019The FBXW2-MSX2-SOX2 axis regulates stem cell property and drug resistance of cancer cells. Proc Natl Acad Sci U S A. 2019 Sep 23. pii: 201905973. doi: 10.1073/pnas.1905973116. [Epub ahead of print]. PMID: 31548378
Pan W, Adams JM, Allison MB, Patterson C, Flak JN, Jones J, Strohbehn G, Trevaskis J, Rhodes CJ, Olson DP, Myers MG Jr.2018Essential Role for Hypothalamic Calcitonin Receptor‒Expressing Neurons in the Control of Food Intake by Leptin.
Endocrinology. 2018 Apr 1;159(4):1860-1872. doi: 10.1210/en.2017-03259.
PMID: 29522093
Allison MB, Pan W, MacKenzie A, Patterson C, Shah K, Barnes T, Cheng W, Rupp A, Olson DP, Myers MG Jr.2018Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action. Diabetes. 2018 Jun;67(6):1093-1104. PMID: 29535089
Allan CM, Heizer PJ, Tu Y, Sandoval NP, Jung RS, Morales JE, Sajti E, Troutman TD, Saunders TL, Cusanovich DA, Beigneux AP, Romanoski CE, Fong LG, Young SG.2018An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner. J Lipid Res. 2018 Dec 31. pii: jlr.M091322. doi: 10.1194/jlr.M091322. [Epub ahead of print]. PMID: 30598475
Bélanger C, Bérubé-Simard FA, Leduc E, Bernas G, Campeau PM, Lalani SR, Martin DM, Bielas S, Moccia A, Srivastava A, Silversides DW, Pilon N. 2018Dysregulation of cotranscriptional alternative splicing underlies CHARGE syndrome. Proc Natl Acad Sci U S A. 115:E620-E629.
Bodur C, Kazyken D, Huang K, Ekim Ustunel B, Siroky KA, Tooley AS, Gonzalez IE, Foley DH, Acosta-Jaquez HA, Barnes TM, Steinl GK, Cho KW, Lumeng CN, Riddle SM, Myers MG Jr, Fingar DC.2018The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists. EMBO J. 2018 Jan 4;37(1):19-38. PMID: 29150432
Chen C, Holth JK, Bunton-Stasyshyn R, Anumonwo CK, Meisler MH, Noebels JL, Isom LL.2018Mapt deletion fails to rescue premature lethality in two models of sodium channel epilepsy. Ann Clin Transl Neurol. 2018 Jul 5;5(8):982-987. PMID: 30128323
Cho KR.2018Is "Ovarian" Cancer a Misnomer? Exploring Ovarian Cancer Origins in the Muse. Trans Am Clin Climatol Assoc. 2018;129:40-47.
Codner GF, Mianné J, Caulder A, Loeffler J, Fell R, King R, Allan AJ, Mackenzie M, Pike FJ, McCabe CV, Christou S, Joynson S, Hutchison M, Stewart ME, Kumar S, Simon MM, Agius L, Anstee QM, Volynski KE, Kullmann DM, Wells S, Teboul L. 2018Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants. BMC Biol. 16:70.
Cunningham GM, Flores LC, Roman MG, Cheng C, Dube S, Allen C, Valentine JM, Hubbard GB, Bai Y, Saunders TL, Ikeno Y. 2018Thioredoxin overexpression in both the cytosol and mitochondria accelerates age-related disease and shortens lifespan in male C57BL/6 mice. Geroscience. 2018 Aug 18. doi: 10.1007/s11357-018-0039-6. [Epub ahead of print]
Epling D, Hu Y, Smith DE.2018Evaluating the intestinal and oral absorption of the prodrug valacyclovir in wildtype and huPepT1 transgenic mice. Biochem Pharmacol. 155:1-7. 
Feinberg TY, Zheng H, Liu R, Wicha MS, Yu SM, Weiss SJ. 2018Divergent Matrix-Remodeling Strategies Distinguish Developmental from Neoplastic Mammary Epithelial Cell Invasion Programs. Dev Cell. 2018 Oct 22;47(2):145-160.e6. PMID: 30269950
Fearon ER.2018Molecular Features and Mouse Models of Colorectal Cancer. Trans Am Clin Climatol Assoc. 2018;129:56-62.
Goldstein CA, O'Brien LM, Bergin IL, Saunders TL.2018The effect of repeated light-dark shifts on uterine receptivity and early gestation in mice undergoing embryo transfer. Syst Biol Reprod Med. 64:103-111. 
Grimley E, Dressler GR. 2018Are Pax proteins potential therapeutic targets in kidney disease and cancer? 2018. Kidney Int. 94:259-267.
Gu B, Posfai E, Rossant J. 2018Efficient generation of targeted large insertions by microinjection into two-cell-stage mouse embryos. Nat Biotechnol. 36:632-637.
Hrycaj SM, Marty-Santos L, Cebrian C, Rasky AJ, Ptaschinski C, Lukacs NW, Wellik DM.2018Hox5 genes direct elastin network formation during alveologenesis by regulatingmyofibroblast adhesion. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10605-E10614. PMID: 30348760
Hull JM, Isom LL.2018Voltage-gated sodium channel β subunits: The power outside the pore in brain development and disease. Neuropharmacology. 132:43-57. 
Hu Y, Song F, Jiang H, Nuñez G, Smith DE.2018SLC15A2 and SLC15A4 Mediate the Transport of Bacterially Derived Di/Tripeptides To Enhance the Nucleotide-Binding Oligomerization Domain-Dependent Immune Response in Mouse Bone Marrow-Derived Macrophages. J Immunol. 2018 Jul 15;201(2):652-662. PMID: 29784761
Jiang L, Su H, Keogh JM, Chen Z, Henning E, Wilkinson P, Goodyer I, Farooqi IS, Rui L.2018Neural deletion of Sh2b1 results in brain growth retardation and reactive aggression. FASEB J. 2018 Apr;32(4):1830-1840. PMID: 29180441
Kim JW, Zhang H, Seymen F, Koruyucu M, Hu Y, Kang J, Kim YJ, Ikeda A, Kasimoglu Y, Bayram M, Zhang C, Kawasaki K, Bartlett JD, Saunders TL, Simmer JP, Hu JC.2018Mutations in RELT Cause Autosomal Recessive Amelogenesis Imperfecta. Clin Genet. 2018 Dec 3. doi: 10.1111/cge.13487. [Epub ahead of print]. PMID: 30506946
Kruger AN, Ellison Q, Brogley MA, Gerlinger ER, Mueller JL. 2018Male mice with large inversions or deletions of X-chromosome palindrome arms are fertile and express their associated genes during post-meiosis.Sci Rep. 8:8985.
Lovat F, Fassan M, Sacchi D, Ranganathan P4, Palamarchuk A, Bill M, Karunasiri M, Gasparini P, Nigita G, Distefano R, Veneziano D, Dorrance AM, Garzon R, Croce CM.2018Knockout of both miR-15/16 loci induces acute myeloid leukemia. Proc Natl Acad Sci U S A. 2018 Nov 26. pii: 201814980. doi: 10.1073/pnas.1814980115. [Epub ahead of print]. PMID: 30478046
Liu Y, Jiang L, Sun C, Ireland N, Shah YM, Liu Y, Rui L.2018Insulin/Snail1 axis ameliorates fatty liver disease by epigenetically suppressing lipogenesis. Nat Commun. 2018 Jul 16;9(1):2751. PMID: 30013137
Liu M, Weiss MA, Arunagiri A, Yong J, Rege N, Sun J, Haataja L, Kaufman RJ, Arvan P.2018Biosynthesis, structure, and folding of the insulin precursor protein. Diabetes Obes Metab. 2018 Sep;20 Suppl 2:28-50. PMID: 30230185
Ma X, Das NK, Castillo C, Gourani A, Perekatt AO, Verzi MP, Shah YM.2018SMAD family member 3 (SMAD3) and SMAD4 repress HIF2a-dependent iron-regulatory genes. J Biol Chem. 2019 Jan 18. pii: jbc.RA118.005549. PMID: 30659096
Ma X, Zhang H, Xue X, Shah YM.2018Hypoxia-inducible factor 2α (HIF-2α) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity. J Biol Chem. 292:17046-17056.
Mancuso P, Curtis JL, Freeman CM, Peters-Golden M, Weinberg JB, Myers MG. 2018Ablation of the Leptin receptor in Myeloid Cells Impairs Pulmonary Clearance of Streptococcus Pneumoniae and Alveolar Macrophage Bactericidal Function. Am J Physiol Lung Cell Mol Physiol. 315:L78-L86.
Marie C, Clavairoly A, Frah M, Hmidan H, Yan J, Zhao C, Van Steenwinckel J, Daveau R, Zalc B, Hassan B, Thomas JL, Gressens P, Ravassard P, Moszer I, Martin DM, Lu QR, Parras C. 2018Oligodendrocyte precursor survival and differentiation requires chromatinremodeling by Chd7 and Chd8. Proc Natl Acad Sci U S A. 115(35):E8246-E8255. PMID: 30108144
Miyasaka Y, Uno Y, Yoshimi K, Kunihiro Y, Yoshimura T, Tanaka T, Ishikubo H, Hiraoka Y, Takemoto N, Tanaka T, Ooguchi Y, Skehel P, Aida T, Takeda J, Mashimo T. 2018CLICK: one-step generation of conditional knockout mice. BMC Genomics. 19:318.
Moriguchi T, Hoshino T, Rao A, Yu L, Takai J, Uemura S, Ise K, Nakamura Y, Lim KC, Shimizu R, Yamamoto M, Engel JD. 2018A Gata3 3' distal otic vesicle enhancer directs inner ear-specific Gata3 expression. Mol Cell Biol. 2018 Aug 20. pii: MCB.00302-18. doi: 10.1128/MCB.00302-18. [Epub ahead of print]  
Nath SR, Yu Z, Gipson TA, Marsh GB, Yoshidome E, Robins DM, Todi SV, Housman DE, Lieberman AP.  2018Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. J Clin Invest. 2018 Aug 1;128(8):3630-3641. 
Pan W, Adams JM, Allison MB, Patterson C, Flak JN, Jones J, Strohbehn G, Trevaskis J, Rhodes CJ, Olson DP, Myers MG Jr.2018Essential Role for Hypothalamic Calcitonin Receptor‒Expressing Neurons in the Control of Food Intake by Leptin. Endocrinology. 2018 Apr 1;159(4):1860-1872. PMID: 29522093
Pan WW, Myers MG Jr. 2018Leptin and the maintenance of elevated body weight..  Nat Rev Neurosci. 2018 Feb;19(2):95-105.
Razumilava N, Shiota J, Mohamad Zaki NH, Ocadiz-Ruiz R, Cieslak CM, Zakharia K, Allen BL, Gores GJ, Samuelson LC, Merchant JL.2018Hedgehog Signaling Modulates Interleukin-33-Dependent Extrahepatic Bile Duct Cell Proliferation in Mice. Hepatol Commun. 2018 Dec 11;3(2):277-292. PMID: 30766964
Rupp AC, Allison MB, Jones JC, Patterson CM, Faber CL, Bozadjieva N, Heisler LK, Seeley RJ, Olson DP, Myers MG Jr.2018Specific subpopulations of hypothalamic leptin receptor-expressing neurons mediate the effects of early developmental leptin receptor deletion on energy balance. Mol Metab. 2018 Aug;14:130-138. PMID: 29914853
Sagner A, Gaber ZB, Delile J, Kong JH, Rousso DL, Pearson CA, Weicksel SE, Melchionda M, Mousavy Gharavy SN, Briscoe J, Novitch BG. 2018Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics. PLoS Biol. 16:e2003127. PubMed PMID: 29389974
Sakr M, Li XY, Sabeh F, Feinberg TY, Tesmer JJG, Tang Y, Weiss SJ. 2018Tracking the Cartoon mouse phenotype: Hemopexin domain-dependent regulation of MT1-MMP pericellular collagenolytic activity. J Biol Chem. 21):8113-8127.
Sato S, Peshenko IV, Olshevskaya EV, Kefalov VJ, Dizhoor AM. 2018GUCY2D Cone-Rod Dystrophy-6 Is a "Phototransduction Disease" Triggered by Abnormal Calcium Feedback on Retinal Membrane Guanylyl Cyclase 1. J Neurosci. 38:2990-3000.
Schofield HK, Zeller J, Espinoza C, Halbrook CJ, Del Vecchio A, Magnuson B, Fabo T, Daylan AEC, Kovalenko I, Lee HJ, Yan W, Feng Y, Karim SA, Kremer DM, Kumar-Sinha C, Lyssiotis CA, Ljungman M, Morton JP, Galbán S, Fearon ER, Pasca di Magliano M.2018Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma. JCI Insight. 2018 Jan 25;3(2). pii: 97422. PMID: 29367463
Sei Y, Feng J, Samsel L, White A, Zhao X, Yun S, Citrin D, McCoy JP, Sundaresan S, Hayes MM, Merchant JL, Leiter A, Wank SA.2018Mature enteroendocrine cells contribute to basal and pathological stem cell dynamics in the small intestine. Am J Physiol Gastrointest Liver Physiol. 2018 Oct 1;315(4):G495-G510. PMID: 29848020
Sharkey LM, Safren N, Pithadia AS, Gerson JE, Dulchavsky M, Fischer S, Patel R, Lantis G, Ashraf N, Kim JH, Meliki A, Minakawa EN, Barmada SJ, Ivanova MI, Paulson HL.2018Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly. Proc Natl Acad Sci U S A. 2018 Oct 17. pii: 201810522. doi: 10.1073/pnas.1810522115. [Epub ahead of print] PMID: 30333186
Tomberg K, Westrick RJ, Kotnik EN, Cleuren AC, Siemieniak DR, Zhu G, Saunders TL, Ginsburg D. 2018Whole exome sequencing of ENU-induced thrombosis modifier mutations in the mouse. PLoS Genet. 14:e1007658.
Triner D, Devenport SN, Ramakrishnan SK, Ma X, Frieler RA, Greenson JK, Inohara N, Nunez G, Colacino JA, Mortensen RM, Shah YM. 2018Neutrophils Restrict Tumor-Associated Microbiota to Reduce Growth and Invasion of Colon Tumors in Mice. Gastroenterology. pii: S0016-5085(18)35399-X. doi: 10.1053/j.gastro.2018.12.003. [Epub ahead of print]
Triner D, Castillo C, Hakim JB, Xue X, Greenson JK, Nuñez G, Chen GY, Colacino JA, Shah YM. 2018Myc-Associated Zinc Finger Protein Regulates the Pro-Inflammatory Response in Colitis and Colon Cancer via STAT3 Signaling. Mol Cell Biol. 2018 Sep 4. pii: MCB.00386-18. doi: 10.1128/MCB.00386-18. [Epub ahead of print]
Trissal MC, Wong TN, Yao JC, Ramaswamy R, Kuo I, Baty J, Sun Y, Jih G, Parikh N, Berrien-Elliott MM, Fehniger TA, Ley TJ, Maillard I, Reddy PR, Link DC.2018MIR142 Loss-of-Function Mutations Derepress ASH1L to Increase HOXA Gene Expression and Promote Leukemogenesis. Cancer Res. 78:3510-3521.
Veeraraghavan R, Hoeker GS, Alvarez-Laviada A, Hoagland D, Wan X, King DR, Sanchez-Alonso J, Chen C, Jourdan J, Isom LL, Deschenes I, Smyth JW, Gorelik J, Poelzing S, Gourdie RG. 2018The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation. Elife. 2018 Aug 14;7. pii: e37610. PMID: 30106376
Walton KD, Mishkind D, Riddle MR, Tabin CJ, Gumucio DL.2018Blueprint for an intestinal villus: Species-specific assembly required. Wiley Interdiscip Rev Dev Biol. 2018 Jul;7(4):e317. doi: 10.1002/wdev.317. Epub 2018 Mar 7. Review. PMID: 29513926
Wang L, Burger LL, Greenwald-Yarnell ML, Myers MG Jr, Moenter SM.2018Glutamatergic Transmission to Hypothalamic Kisspeptin Neurons Is Differentially Regulated by Estradiol through Estrogen Receptor α in Adult Female Mice. J Neurosci. 2018 Jan 31;38(5):1061-1072. PMID: 29114074
Wang Q, Yan R, Pinnell N, McCarter AC, Oh Y, Liu Y, Sha C, Garber NF, Chen Y, Wu Q, Ku CJ, Tran I, Serna Alarcon A, Kuick R, Engel JD, Maillard I, Cierpicki T, Chiang MY. 2018Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development. Blood. 132:1279-1292.
Watts SW, Darios ES, Mullick AE, Garver H, Saunders TL, Hughes ED, Filipiak WE, Zeidler MG, McMullen N, Sinal CJ, Kumar RK, Ferland DJ, Fink GD.2018The chemerin knockout rat reveals chemerin dependence in female, but not male, experimental hypertension. FASEB J. fj201800479. doi: 10.1096/fj.201800479. [Epub ahead of print] PMID: 29906243
Xu J, Zhang L, Xie M, Li Y, Huang P, Saunders TL, Fox DA, Rosenquist R, Lin F. 2018Role of Complement in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy. J Immunol. 200:4094-4101. PMID: 29695418
Xing Y, Morohashi KI, Ingraham HA, Hammer GD.2018Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1. Development.144:3798-3807. PMID: 28893949
Yao H, Hill SF, Skidmore JM, Sperry ED, Swiderski DL, Sanchez GJ, Bartels CF, Raphael Y, Scacheri PC, Iwase S, Martin DM. 2018CHD7 represses the retinoic acid synthesis enzyme ALDH1A3 during inner ear development. JCI Insight. 3(4). 
Yao X, Zhang M, Wang X, Ying W, Hu X, Dai P, Meng F, Shi L, Sun Y, Yao N, Zhong W, Li Y, Wu K, Li W, Chen ZJ, Yang H.2018Tild-CRISPR Allows for Efficient and Precise Gene Knockin in Mouse and Human Cells. Dev Cell. 45:526-536.
Ye W, Takabayashi H, Yang Y, Mao M, Hibdon ES, Samuelson LC, Eaton KA, Todisco A.2018Regulation of Gastric Lgr5+ve Cell Homeostasis by Bone Morphogenetic Protein (BMP) Signaling and Inflammatory Stimuli. Cell Mol Gastroenterol Hepatol. 2018 Jan 31;5(4):523-538. PMID: 29930977
Yu J, Koenig RJ. 2018Thyroid-specific PPARγ deletion is benign in the mouse. Endocrinology. doi: 10.1210/en.2017-03163. [Epub ahead of print]
Baek AE, Sutton NR, Petrovic-Djergovic D, Liao H, Ray JJ, Park J, Kanthi Y, Pinsky DJ. 2017Ischemic Cerebroprotection Conferred by Myeloid Lineage-Restricted or Global CD39 Transgene Expression. Circulation. 135:2389-2402.
Barnes RH 2nd, Akama T, Öhman MK, Woo MS, Bahr J, Weiss SJ, Eitzman DT, Chun TH. 2017Membrane-Tethered Metalloproteinase Expressed by Vascular Smooth Muscle Cells Limits the Progression of Proliferative Atherosclerotic Lesions. J Am Heart Assoc. 6(7). 
Borges BC, Garcia-Galiano D, Cruz-Machado SS, Han X, Gavrilina GB, Saunders TL, Auchus RJ, Hammoud S, Smith GD, Elias CF. 2017Obesity-induced infertility in male mice is associated with disruption of Crisp4 expression and sperm fertilization capacity. Endocrinology. DOI: 10.1210/en.2017-00295
Bouza AA, Isom LL. 2017Voltage-Gated Sodium Channel β Subunits and Their Related Diseases. In: Handbook of Experimental Pharmacology. Springer, Berlin, Heidelberg. 
Chen X, Keep RF, Liang Y, Zhu HJ, Hammarlund-Udenaes M, Hu Y, Smith DE. 2017Influence of Peptide Transporter 2 (PEPT2) on the Distribution of Cefadroxil in Mouse Brain: A Microdialysis Study. Biochem Pharmacol. 131:89-97.
Decot HK, Namboodiri VM, Gao W, McHenry JA, Jennings JH, Lee SH, Kantak PA, Jill Kao YC, Das M, Witten IB, Deisseroth K, Shih YI, Stuber GD. 2017Coordination of Brain-Wide Activity Dynamics by Dopaminergic Neurons. Neuropsychopharmacology. 42:615-627.
Dinkelmann M, Spehalski E, Stoneham T, Buis J, Wu Y, Sekiguchi JM, Ferguson DO.2017Multiple functions of MRN in end-joining pathways during isotype class switching. Nat Struct Mol Biol. 16:808-813.
Fernandes DJ, Ellegood J, Askalan R, Blakely RD, Dicicco-Bloom E, Egan SE, Osborne LR, Powell CM, Raznahan A, Robins DM, Salter MW, Sengar AS, Veenstra-VanderWeele J, Henkelman RM, Lerch JP. 2017Spatial gene expression analysis of neuroanatomical differences in mouse models. Neuroimage. 163:220-230.
Flak JN, Arble D, Pan W, Patterson C, Lanigan T, Goforth PB, Sacksner J, Joosten M, Morgan DA, Allison MB, Hayes J, Feldman E, Seeley RJ, Olson DP, Rahmouni K, Myers MG Jr. 2017A leptin-regulated circuit controls glucose mobilization during noxious stimuli. J Clin Invest. 127:3103-3113.
Guo L, Zhang P, Chen Z, Xia H, Li S, Zhang Y, Kobberup S, Zou W, Lin JD. 2017Hepatic neuregulin 4 signaling defines an endocrine checkpoint for steatosis-to-NASH progression. J Clin Invest. 127:4449-4461. 
Haller ST, Kumarasamy S, Folt DA, Wuescher LM, Stepkowski S, Karamchandani M, Waghulde H, Mell B, Chaudhry M, Maxwell K, Upadhyaya S, Drummond CA, Tian J, Filipiak WE, Saunders TL, Shapiro JI, Joe B, Cooper CJ. 2017Targeted disruption of Cd40 in a genetically hypertensive rat model attenuates renal fibrosis and proteinuria, independent of blood pressure. Kidney Int. 91:365-374.
Home P, Kumar RP, Ganguly A, Saha B, Milano-Foster J, Bhattacharya B, Ray S, Gunewardena S, Paul A, Camper SA, Fields PE, Paul S. 2017Genetic redundancy of GATA factors in the extraembryonic trophoblast lineage ensures the progression of preimplantation and postimplantation mammalian development. Development. 144:876-888.
Ji T, Takabayashi H, Mao M, Han X, Xue X, Brazil JC, Eaton KA, Shah YM, Todisco A. 2017Regulation and function of Bone Morphogenetic Protein signaling in colonic injury and inflammation. Am J Physiol Gastrointest Liver Physiol. 312:G24-G33.
Khoriaty R, Vogel N, Hoenerhoff MJ, Sans MD, Zhu G, Everett L, Nelson B, Durairaj H, McKnight B, Zhang B, Ernst SA, Ginsburg D, Williams JA. 2017SEC23B is required for pancreatic acinar cell function in adult mice. Mol Biol Cell. 28:2146-2154. 
Ku CJ, Sekiguchi JM, Panwar B, Guan Y, Takahashi S, Yoh K, Maillard I, Hosoya T, Engel JD. 2017GATA3 Abundance Is a Critical Determinant of T Cell Receptor β Allelic Exclusion. Mol Cell Biol. 37. pii: e00052-17.
Lapinski PE, Lubeck BA, Chen D, Doosti A, Zawieja SD, Davis MJ, King PD. 2017RASA1 regulates the function of lymphatic vessel valves in mice. J Clin Invest. 127:2569-2585.
Lopez-Santiago LF, Yuan Y, Wagnon JL, Hull JM, Frasier CR, O’Malley HA, Meisler MH, Isom LL.2017Neuronal hyperexcitability in a mouse model of SCN8A epileptic encephalopathy. Proc Natl Acad Sci U S A. 114:2383-2388.
Ma X, Zhang H, Xue X, Shah YM. 2017Hypoxia-inducible factor 2α (HIF-2α) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity. J Biol Chem. 292:17046-17056.
Maclary E, Hinten M, Harris C, Sethuraman S, Gayen S, Kalantry S.2017 PRC2 represses transcribed genes on the imprinted inactive X chromosome in mice.Genome Biol. 18:82.
Merchant JL, Ding L.2017Hedgehog Signaling Links Chronic Inflammation to Gastric Cancer Precursor Lesions. Cell Mol Gastroenterol Hepatol. 3:201-210.
Mohsen Z, Mohsen, Z, Sim H, Garcia-Galiano D, Bellefontaine N, Saunders TL, Elias CF. 2017Sexually dimorphic distribution of Prokr2 neurons revealed by the Prokr2-Cre mouse model. Brain Struct Funct. 222:4111-4129. PMID: 28616754
Ocadiz-Ruiz R, Photenhauer AL, Hayes MM, Ding L, Fearon ER, Merchant JL. 2017ZBP-89 function in colonic stem cells and during butyrate-induced senescence. Oncotarget. 8:94330-94344. 
Ottolini M, Barker BS, Gaykema RP, Meisler MH, Patel MK.2017Aberrant Sodium Channel Currents and Hyperexcitability of Medial Entorhinal Cortex Neurons in a Mouse Model of SCN8A Encephalopathy. J Neurosci. 37:7643-7655.
Ramani B, Harris GM, Huang R, Seki T, Murphy GG, Carmo Costa MD, Fischer S, Saunders TL, Xia G, McEachin RC, Paulson HL. 2017A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript. Hum Mol Genet. doi: 10.1093/hmg/ddx176. [Epub ahead of print]
Rastall DPW, Alyaquob FS, O'Connell P, Pepelyayeva Y, Peters D, Godbehere-Roosa S, Pereira-Hicks C, Aldhamen YA, Amalfitano A. 2017Mice expressing human ERAP1 variants associated with ankylosing spondylitis have altered T-cell repertoires and NK cell functions, as well as increased in utero and perinatal mortality. Int Immunol. 29:277-289.
Razumilava N, Gumucio DL, Samuelson LC, Shah YM, Nusrat A, Merchant JL.2017Indian Hedgehog Suppresses Intestinal Inflammation. Cell Mol Gastroenterol Hepatol. 2017 Oct 31;5(1):63-64. PMID: 29276751
Rux DR, Song JY, Pineault KM, Mandair GS, Swinehart IT, Schlientz AJ, Garthus KN, Goldstein SA, Kozloff KM, Wellik DM. 2017Hox11 Function Is Required for Region-Specific Fracture Repair. J Bone Miner Res. 32:1750-1760.
Sakamoto N, Feng Y, Stolfi C, Kurosu Y, Green M, Lin J, Green ME, Sentani K, Yasui W, McMahon M, Hardiman KM, Spence JR, Horita N, Greenson JK, Kuick R, Cho KR, Fearon ER.2017BRAFV600E cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis. Elife. Jan 10;6.
Soofi A, Wolf KI, Emont MP, Qi N, Martinez-Santibanez G, Grimley E, Ostwani W, Dressler GR. 2017The kielin/chordin-like protein (KCP) attenuates high-fat diet-induced obesity and metabolic syndrome in mice. J Biol Chem. 292:9051-9062.
Spehalski E, Capper KM, Smith CJ, Morgan MJ, Dinkelmann M, Buis J, Sekiguchi JM, Ferguson DO. 2017MRE11 promotes tumorigenesis by facilitating resistance to oncogene-induced replication stress. Cancer Res. 77: 5327-5338.
Sprissler RS, Wagnon JL, Bunton-Stasyshyn RK, Meisler MH, Hammer MF. 2017Altered gene expression profile in a mouse model of SCN8Aencephalopathy. Exp Neurol. 288:134-141.
Sun L, Pham TT, Cornell TT, McDonough KL, McHugh WM, Blatt NB, Dahmer MK, Shanley TP.2017Myeloid-Specific Gene Deletion of Protein Phosphatase 2A Magnifies MyD88- and TRIF- Dependent Inflammation following Endotoxin Challenge. J Immunol. 198:404-416.
Sundaresan S, Meininger CA, Kang AJ, Photenhauer AL, Hayes MM, Sahoo N, Grembecka J, Cierpicki T, Ding L, Giordano TJ, Else T, Madrigal DJ, Low MJ, Campbell F, Baker AM, Xu H, Wright NA, Merchant JL. 2017Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells. Gastroenterology. [Epub ahead of print]
Sutton NR, Hayasaki T, Hyman MC, Anyanwu AC, Liao H, Petrovic-Djergovic D, Badri L, Baek AE, Walker N, Fukase K, Kanthi Y, Visovatti SH, Horste EL, Ray JJ, Goonewardena SN, Pinsky DJ. 2017Ectonucleotidase CD39-driven control of postinfarction myocardial repair and rupture. JCI Insight. 2:e89504.
Tang Y, Weiss SJ. 2017Snail/Slug-YAP/TAZ complexes cooperatively regulate mesenchymal stem cell function and bone formation. Cell Cycle. 16:399-405.
Taniguchi K, Moroishi T, de Jong PR, Krawczyk M, Grebbin BM, Luo H, Xu RH, Golob-Schwarzl N, Schweiger C, Wang K, Di Caro G, Feng Y, Fearon ER, Raz E, Kenner L, Farin HF, Guan KL, Haybaeck J, Datz C, Zhang K, Karin M. 2017YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis. Proc Natl Acad Sci U S A. 114:1643-1648.
Triner D, Xue X, Schwartz AJ, Jung I, Colacino JA, Shah YM. 2017Epithelial Hypoxia-Inducible Factor 2? Facilitates the Progression of Colon Tumors through Recruiting Neutrophils. Mol Cell Biol. 37(5). e00481-16.
Uematsu A, Tan BZ, Ycu EA, Cuevas JS, Koivumaa J, Junyent F, Kremer EJ, Witten IB, Deisseroth K, Johansen JP.2017Modular organization of the brainstem noradrenaline system coordinates opposing learning states. Nat Neurosci. 20:1602-1611.
Verhaegen ME, Mangelberger D, Harms PW, Eberl M, Wilbert DM, Meireles J, Bichakjian CK, Saunders TL, Wong SY, Dlugosz AA. 2017Merkel cell polyomavirus small T antigen initiates Merkel cell carcinoma-like tumor development in mice. Cancer Res. 77:3151-3157.
Wang Y, Huang D, Chen KY, Cui M, Wang W, Huang X, Awadellah A, Li Q, Friedman A, Xin WW, Di Martino L, Cominelli F, Miron A, Chan R, Fox JG, Xu Y, Shen X, Kalady MF, Markowitz S, Maillard I, Lowe JB, Xin W, Zhou L.2017Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma. Gastroenterology. 152:193-205.
Wang Q, Yan R, Ku CJ, Sekiguchi JM, Panwar B, Guan Y, Takahashi S, Yoh K, Maillard I, Hosoya T, Engel JD. 2017GATA3 Abundance Is a Critical Determinant of T Cell Receptor β Allelic Exclusion. Mol Cell Biol. 37(12). pii: e00052-17.
Westrick RJ, Tomberg K, Siebert AE, Zhu G, Winn ME, Dobies SL, Manning SL, Brake MA, Cleuren AC, Hobbs LM, Mishack LM, Johnston AJ, Kotnik E, Siemieniak DR, Xu J, Li JZ, Saunders TL, Ginsburg D. 2017Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci. Proc Natl Acad Sci U S A. 114:9659-9664.
Xu T, Zhang H, Park SS, Venneti S, Kuick R, Ha K, Michael LE, Santi M, Uchida C, Uchida T, Srinivasan A, Olson JM, Dlugosz AA, Camelo-Piragua S, Rual JF. 2017 Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis. Neoplasia. 19:216-225.
Xue X, Bredell BX, Anderson ER, Martin A, Mays C, Nagao-Kitamoto H, Huang S, Gyrffy B, Greenson JK, Hardiman K, Spence JR, Kamada N, Shah YM. 2017Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer. Proc Natl Acad Sci U S A. 114:E9608-E9617.
Zhai Y, Wu R, Kuick R, Sessine MS, Schulman S, Green M, Fearon ER, Cho KR. 2017High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease. J Pathol. 243:16-25.
Zhang H, Dou Y. 2017Reprogram Murine Epiblast Stem Cells by Epigenetic Inhibitors. Bio Protoc. 7(5). pii: e2168.
Zhang H, Nair V, Saha J, Atkins KB, Hodgin JB, Saunders TL, Myers MG Jr, Werner T, Kretzler M, Brosius FC. 2017Podocyte-specific JAK2 overexpression worsens diabetic kidney disease in mice. 2017. Kidney Int. 2017 May 26. pii: S0085-2538(17)30230-2. [Epub ahead of print]
Zhang Y, Yu J, Grachtchouk V, Qin T, Lumeng CN, Sartor MA, Koenig RJ. 2017Genomic binding of PAX8-PPARG fusion protein regulates cancer-related pathways and alters the immune landscape of thyroid cancer. Oncotarget. 8:5761-5773.
Bao Y, Willis BC, Frasier CR, Lopez-Santiago LF, Lin X, Ramos-Mondragón R, Auerbach DS, Chen C, Wang Z, Anumonwo J, Valdivia HH, Delmar M, Jalife J, Isom LL.2016Scn2b Deletion in Mice Results in Ventricular and Atrial Arrhythmias. Circ Arrhythm Electrophysiol. 9(12). 
Burke LK, Doslikova B, D’Agostino G, Greenwald-Yarnell M, Georgescu T, Chianese R, Martinez de Morentin PB, Ogunnowo-Bada E, Cansell C, Valencia-Torres L, Garfield AS, Apergis-Schoute J, Lam DD, Speakman JR, Rubinstein M, Low MJ, Rochford JJ, Myers MG, Evans ML, Heisler LK.2016Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons. Mol Metab. 5:245-252.
Chen L, Martino V, Dombkowski A, Williams T, West-Mays J, Gage PJ.2016AP-2beta Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development. Invest Ophthalmol Vis Sci. 57:1072-81.
Chen G, Yu D, Nian X, Liu J, Koenig RJ, Xu B, Sheng L. 2016LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL). Sci Rep. 6:35531.
Connor AL, Kelley PM, Tempero RM. 2016Lymphatic endothelial lineage assemblage during corneal lymphangiogenesis. Lab Invest. 96:270-282.
Chung C, Elrick MJ, Dell’Orco JM, Qin ZS, Kalyana-Sundaram S, Chinnaiyan AM, Shakkottai VG, Lieberman AP.2016Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease. PLoS Genet. 12:e1006042.
Chung C, Puthanveetil P, Ory DS, Lieberman AP. 2016Genetic and pharmacological evidence implicates cathepsins in Niemann-Pick C cerebellar degeneration. Hum Mol Genet. 25:1434-46.
Connor AL, Kelley PM, Tempero RM. 2016Lymphatic endothelial lineage assemblage during corneal lymphangiogenesis. Lab Invest. 96:270-282.
Dautan D, Souza AS, Huerta-Ocampo I, Valencia M, Assous M, Witten IB, Deisseroth K, Tepper JM, Bolam JP, Gerdjikov TV, Mena-Segovia J.2016Segregated cholinergic transmission modulates dopamine neurons integrated in distinct functional circuits. Nat Neurosci. 19:1025-33.
Davis SW, Keisler JL, Pérez-Millán MI, Schade V, Camper SA. 2016All hormone-producing cell types of the pituitary intermediate and anterior lobes derive from Prop1 expressing progenitors. Endocrinology. 157:1385-96.
Di Girolamo D, Ambrosio R, De Stefano MA, Mancino G, Porcelli T, Luongo C, Di Cicco E, Scalia G, Vecchio LD, Colao A, Dlugosz AA, Missero C, Salvatore D, Dentice M.2016Reciprocal interplay between thyroid hormone and microRNA-21 regulates hedgehog pathway-driven skin tumorigenesis. J Clin Invest. 126:2308-2320.
Ding L, El Zaatari M, Merchant JL.2016Recapitulating Human Gastric Cancer Pathogenesis: Experimental Models of Gastric Cancer. Adv Exp Med Biol. 2016;908:441-478.
Ding L, Hayes MM, Photenhauer A, Eaton KA, Li Q, Ocadiz-Ruiz R, Merchant JL.2016Schlafen 4-expressing myeloid-derived suppressor cells are induced during murine gastric metaplasia. J Clin Invest. 126:2867-2880.
Dizhoor AM, Olshevskaya EV, Peshenko IV. 2016The R838S Mutation in Retinal Guanylyl Cyclase 1 (RetGC1) Alters Calcium Sensitivity of cGMP Synthesis in the Retina and Causes Blindness in Transgenic Mice. J Biol Chem. 291:24504-24516. 
Ermilov AN, Kumari A, Li L, Joiner AM, Grachtchouk MA, Allen BL, Dlugosz AA, Mistretta CM. 2016Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling. PLoS Genet. 12:e1006442
Essien BE, Sundaresan S, Ocadiz-Ruiz R, Chavis A, Tsao AC, Tessier AJ, Hayes MM, Photenhauer A, Saqui-Salces M, Kang AJ, Shah YM, Gyorffy B, Merchant JL.2016Transcription Factor ZBP-89 Drives a Feedforward Loop of beta-Catenin Expression in Colorectal Cancer. Cancer Res. 76:6877-6887.
Feinberg TY, Rowe RG, Saunders TL, Weiss SJ. 2016Functional roles of MMP14 and MMP15 in early postnatal mammary gland development. Development. 143:3956-3968.
Frasier CR, Wagnon JL, Bao YO, McVeigh LG, Lopez-Santiago LF, Meisler MH, Isom LL. 2016Cardiac arrhythmia in a mouse model of sodium channel SCN8A epileptic encephalopathy. Proc Natl Acad Sci U S A. 113:12838–12843.
Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS.2016Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 409:218-233.
Gergics P, Christian HC, Choo MS, Ajmal A, Camper SA. 2016Gene Expression in Mouse Thyrotrope Adenoma: Transcription Elongation Factor Stimulates Proliferation. Endocrinology. 157:3631-46.
Giorgetti E, Yu Z, Chua JP, Shimamura R, Zhao L, Zhu F, Venneti S, Pennuto M, Guan Y, Hung G, Lieberman AP. 2016Rescue of Metabolic Alterations in AR113Q Skeletal Muscle by Peripheral Androgen Receptor Gene Silencing. Cell Rep. 17:125-36
Greenwald-Yarnell ML, Marsh C, Allison MB, Patterson CM, Kasper C, MacKenzie A, Cravo R, Elias CF, Moenter SM, Myers MG Jr. 2016ERalpha in Tac2 Neurons Regulates Puberty Onset in Female Mice. Endocrinology. 157:1555-1565.
He D, Marie C, Zhao C, Kim B, Wang J, Deng Y, Clavairoly A, Frah M, Wang H, He X, Hmidan H, Jones BV, Witte D, Zalc B, Zhou X, Choo DI, Martin DM, Parras C, Lu QR. 2016Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination. Nat Neurosci. 19:678-689.
Hu Y, Smith DE. 2016Species differences in the pharmacokinetics of cefadroxil as determined in wildtype and humanized PepT1 mice. Biochem Pharmacol. 107:81-90.
Hsu SH, Delgado ER, Otero PA, Teng KY, Kutay H, Meehan KM, Moroney JB, Monga JK, Hand NJ, Friedman JR, Ghoshal K, Duncan AW.2016MicroRNA-122 regulates polyploidization in the murine liver. Hepatology. 64:599-615.
Johnson GD, Jodar M, Pique-Regi R, Krawetz SA. 2016Nuclease Footprints in Sperm Project Past and Future Chromatin Regulatory Events. Sci Rep. 6:25864.
Kc R, Srivastava A, Wilkowski JM, Richter CE, Shavit JA, Burke DT, Bielas SL. 2016Detection of nucleotide-specific CRISPR/Cas9 modified alleles using multiplex ligation detection. Sci Rep. 6:32048.
Ketchesin KD, Stinnett GS, Seasholtz AF.2016Binge Drinking Decreases Corticotropin-Releasing Factor-Binding Protein Expression in the Medial Prefrontal Cortex of Mice. Alcohol Clin Exp Res. 40(8):1641-50.
Khoriaty R, Everett L, Chase J, Zhu G, Hoenerhoff M, McKnight B, Vasievich MP, Zhang B, Tomberg K, Williams J, Maillard I, Ginsburg D.2016Pancreatic SEC23B deficiency is sufficient to explain the perinatal lethality of germline SEC23B deficiency in mice. Sci Rep. 6:27802.
Kulkarni S, Micci MA, Leser J, Shin C, Tang SC, Fu YY, Liu L, Li Q, Saha M, Li C, Enikolopov G, Becker L, Rakhilin N, Anderson M, Shen X, Dong X, Butte MJ, Song H, Southard-Smith EM, Kapur RP, Bogunovic M, Pasricha PJ.2016Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis. Proc Natl Acad Sci U S A. 114: E3709–E3718.
Lenk GM, Frei CM, Miller AC, Wallen RC, Mironova YA, Giger RJ, Meisler MH.2016Rescue of neurodegeneration in the Fig4 null mouse by a catalytically inactive FIG4 transgene. Hum Mol Genet. 25(2):340-7.
Li CS, Tang F, Zhang P, Jiang T, Saunders TL, Zheng P, Liu Y.2016Trap1a is an X-linked and cell-intrinsic regulator of thymocyte development. Cell Mol Immunol. doi: 10.1038/cmi.2015.108. [Epub ahead of print]
Li Y, Stoll SW, Sekhon S, Talsma C, Camhi MI, Jones JL, Lambert S, Marley H, Rittié L, Grachtchouk M, Fritz Y, Ward NL, Elder JT. 2016Transgenic expression of human amphiregulin in mouse skin: inflammatory epidermal hyperplasia and enlarged sebaceous glands. Exp Dermatol. 25:187-93.
Meisler MH, Helman G, Hammer MF, Fureman BE, Gaillard WD, Goldin AL, Hirose S, Ishii A, Kroner BL, Lossin C, Mefford HC, Parent JM, Patel M, Schreiber J, Stewart R, Whittemore V, Wilcox K, Wagnon JL, Pearl PL, Vanderver A, Scheffer IE.2016SCN8A encephalopathy: Research progress and prospects. Epilepsia. 57:1027-35.
Mironova YA, Lenk GM, Lin JP, Lee SJ, Twiss JL, Vaccari I, Bolino A, Havton LA, Min SH, Abrams CS, Shrager P, Meisler MH, Giger RJ.2016PI(3,5)P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms. Elife. 5. pii: e13023.
Moriguchi T, Yu L, Otsuki A, Ainoya K, Lim KC, Yamamoto M, Engel JD. 2016Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect. Mol Cell Biol. 36:2272-2281.
Ohmura S, Mizuno S, Oishi H, Ku CJ, Hermann M, Hosoya T, Takahashi S, Engel JD. 2016Lineage-affiliated transcription factors bind the Gata3 Tce1 enhancer to mediate lineage-specific programs. J Clin Invest. 126:865-878.
Orefice L, Zimmerman AL, Chirila AM, Sleboda SJ, Head JP, Ginty DD. 2016Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs. Cell. 166:299-313.
Rocchi A, Milioto C, Parodi S, Armirotti A, Borgia D, Pellegrini M, Urciuolo A, Molon S, Morbidoni V, Marabita M, Romanello V, Gatto P, Blaauw B, Bonaldo P, Sambataro F, Robins DM, Lieberman AP, Sorarù G, Vergani L, Sandri M, Pennuto M.2016Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat diet. Acta Neuropathol. 132:127-44.
Rubel CA, Wu SP, Lin L, Wang T, Lanz RB, Li X, Kommagani R, Franco HL, Camper SA, Tong Q, Jeong JW, Lydon JP, DeMayo FJ.2016A Gata2-Dependent Transcription Network Regulates Uterine Progesterone Responsiveness and Endometrial Function. Cell Rep. 17:1414-1425.
Rux DR, Song JY, Swinehart IT, Pineault KM, Schlientz AJ, Trulik KG, Goldstein SA, Kozloff KM, Lucas D, Wellik DM. 2016Regionally Restricted Hox Function in Adult Bone Marrow Multipotent Mesenchymal Stem/Stromal Cells. Dev Cell. 39:653-666. 
Sawada K, Hiraoka M, Abe A, Kelly R, Shayman JA, Ohguro H.2016Prolonged Ocular Inflammation in Endotoxin-Induced Uveitis in Lysosomal Phospholipase A2-Deficient Mice. Curr Eye Res. 9:1-6. [Epub ahead of print]
Soofi A, Wolf KI, Ranghini EJ, Amin MA, Dressler GR. 2016The kielin/chordin-like protein KCP attenuates nonalcoholic fatty liver disease in mice. Am J Physiol Gastrointest Liver Physiol. 311:G587-G598.
Sprissler RS, Wagnon JL, Bunton-Stasyshyn RK, Meisler MH, Hammer MF. 2016Altered gene expression profile in a mouse model of SCN8A encephalopathy. Exp Neurol. 288:134-141. [Epub ahead of print]
Sun C, Jiang L, Liu Y, Shen H, Weiss SJ, Zhou Y, Rui L. 2016Adipose Snail1 Regulates Lipolysis and Lipid Partitioning by Suppressing Adipose Triacylglycerol Lipase Expression. Cell Rep. 17:2015-2027.
Sundaresan S, Kang AJ, Hayes MM, Choi EK, Merchant JL.2016Deletion of Men1 and somatostatin induces hypergastrinemia and gastric carcinoids. Gut. pii: gutjnl-2015-310928. doi: 10.1136/gutjnl-2015-310928. [Epub ahead of print]
Sutton AK, Myers MG Jr, Olson DP. 2016The Role of PVH Circuits in Leptin Action and Energy Balance. Annu Rev Physiol. 78:207-21. doi: 10.1146/annurev-physiol-021115-105347.
Syu LJ, Zhao X, Zhang Y, Grachtchouk M, Demitrack E, Ermilov A, Wilbert DM, Zheng X, Kaatz A, Greenson JK, Gumucio DL, Merchant JL, di Magliano MP, Samuelson LC, Dlugosz AA. 2016Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways. Oncotarget. 7:10255-70.
Tan M, Xu J, Siddiqui J, Feng F, Sun Y.2016Depletion of SAG/RBX2 E3 ubiquitin ligase suppresses prostate tumorigenesis via inactivation of the PI3K/AKT/mTOR axis. Mol Cancer. 15:81.
Valdmanis PN, Gu S, Chu K, Jin L, Zhang F, Munding EM, Zhang Y, Huang Y, Kutay H, Ghoshal K, Lisowski L, Kay MA.2016RNA interference-induced hepatotoxicity results from loss of the first synthesized isoform of microRNA-122 in mice. Nat Med. 22:557-562.
Valencia-Torres L, Olarte-Sánchez CM, Lyons DJ, Georgescu T, Greenwald-Yarnell M, Myers MG, Bradshaw CM, Heisler LK.2016Activation of Ventral Tegmental Area 5-HT2C Receptors Reduces Incentive Motivation. Neuropsychopharmacology. [Epub ahead of print]
Venkatareddy M, Verma R, Kalinowski A, Patel SR, Shisheva A, Garg P.2016Distinct Requirements for Vacuolar Protein Sorting 34 Downstream Effector Phosphatidylinositol 3-Phosphate 5-Kinase in Podocytes Versus Proximal Tubular Cells. J Am Soc Nephrol. 27:2702-19
Wagner MC, Campos-Bilderback SB, Chowdhury M, Flores B, Lai X, Myslinski J, Pandit S, Sandoval RM, Wean SE, Wei Y, Satlin LM, Wiggins RC, Witzmann FA, Molitoris BA.2016Proximal Tubules Have the Capacity to Regulate Uptake of Albumin. J Am Soc Nephrol. 27:482-494.
Wang Y, Huang D, Chen KY, Cui M, Wang W, Huang X, Awadellah A, Li Q, Friedman A, Xin WW, Di Martino L, Cominelli F, Miron A, Chan R, Fox J, Xu Y, Shen X, Kalady MF, Markowitz S, Maillard I, Lowe JB, Xin W, Zhou L.2016Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma. Gastroenterology. pii: S0016-5085(16)35029-6. [Epub ahead of print]
Xie Y, Hu Y, Smith DE. 2016The proton-coupled oligopeptide transporter 1 plays a major role in the intestinal permeability and absorption of 5-aminolevulinic acid. Br J Pharmacol. 173:167-176.
Xie Y, Shen H, Hu Y, Feng MR, Smith DE. 2016Population pharmacokinetic modeling of cefadroxil renal transport in wild-type and Pept2 knockout mice. Xenobiotica. 46:342-249.
Xu P, He Y, Cao X, Valencia-Torres L, Yan X, Saito K, Wang C, Yang Y, Hinton A Jr, Zhu L, Shu G, Myers MG Jr, Wu Q, Tong Q, Heisler LK, Xu Y.2016Activation of Serotonin 2C Receptors in Dopamine Neurons Inhibits Binge-like Eating in Mice.Biol Psychiatry. pii: S0006-3223(16)32470-2. [Epub ahead of print]
Zhai Y, Kuick R, Tipton C, Wu R, Sessine M, Wang Z, Baker SJ, Fearon ER, Cho KR. 2016Arid1a inactivation in an Apc- and Pten-defective mouse ovarian cancer model enhances epithelial differentiation and prolongs survival. J Pathol. 238:21-30.
Zhang H, Gayen S, Xiong J, Zhou B, Shanmugam AK, Sun Y, Karatas H, Liu L, Rao RC, Wang S, Nesvizhskii AI, Kalantry S, Dou Y.2016MLL1 Inhibition Reprograms Epiblast Stem Cells to Naive Pluripotency. 18:4811-4894.
Zhang J, Qiao C, Chang L, Guo Y, Fan Y, Villacorta L, Chen YE, Zhang J.2016Cardiomyocyte Overexpression of FABP4 Aggravates Pressure Overload-Induced Heart Hypertrophy. PLoS One. 11:e0157372.
Zhu S, Larkin D, Lu S, Inouye C, Haataja L, Anjum A, Kennedy R, Castle D, Arvan P. 2016Monitoring C-Peptide Storage and Secretion in Islet β-Cells In Vitro and In Vivo. Diabetes. 65:699-709.
Greenwald-Yarnell ML, Marsh C, Allison MB, Patterson CM, Kasper C, MacKenzie A, Cravo R, Elias CF, Moenter SM, Myers MG Jr.2016ERα in Tac2 Neurons Regulates Puberty Onset in Female Mice. Endocrinology. 2016 Apr;157(4):1555-65. doi: 10.1210/en.2015-1928. Epub 2016 Feb 10.
PMID: 26862996
Lam DD, Attard CA, Mercer AJ, Myers MG Jr, Rubinstein M, Low MJ.2015
Conditional expression of Pomc in the Lepr-positive subpopulation of POMC neurons is sufficient for normal energy homeostasis and metabolism. Endocrinology. 2015 Apr;156(4):1292-302. doi: 10.1210/en.2014-1373. Epub 2015 Jan 16. PMID: 25594696
Abdul-Majeed S, Mell B, Nauli SM, Joe B.2015Cryptorchidism and infertility in rats with targeted disruption of the Adamts16 locus. PLoS One. 9:e100967.
Bednar F, Schofield HK, Collins MA, Yan W, Zhang Y, Shyam N, Eberle JA, Almada LL, Olive KP, Bardeesy N, Fernandez-Zapico ME, Nakada D, Simeone DM, Morrison SJ, Pasca di Magliano M.2015Bmi1 is required for the initiation of pancreatic cancer through an Ink4a-independent mechanism. Carcinogenesis. 36:730-738.
Boye SL, Peterson JJ, Choudhury S, Min SH, Ruan Q, McCullough KT, Zhang Z, Olshevskaya EV, Peshenko IV, Hauswirth WW, Ding XQ, Dizhoor AM, Boye SE. 2015Gene Therapy Fully Restores Vision to the All-Cone Nrl(-/-) Gucy2e(-/-) Mouse Model of Leber Congenital Amaurosis-1. Hum Gene Ther. 26:575-92.
Brinkmeier ML, Geister KA, Jones M, Waqas M, Maillard I, Sally A. Camper SA. 2015The Histone Methyltransferase Gene Absent, Small, or Homeotic Discs-1 Like Is Required for Normal Hox Gene Expression and Fertility in Mice. Biol Reprod. 93:121.
Cacioppo JA, Koo Y, Lin PC, Gal A, Ko C. 2015Generation and characterization of an endothelin-2 iCre mouse. Genesis. 53:245-256.
Castinetti F, Brinkmeier ML, Mortensen AH, Vella KR, Gergics P, Brue T, Hollenberg AN, Gan L, Camper SA.2015ISL1 is necessary for maximal thyrotrope response to hypothyroidism. Mol Endocrinol. 29:1510-1521.
Chua JP, Reddy SL, Yu Z, Giorgetti E, Montie HL, Mukherjee S, Higgins J, McEachin RC, Robins DM, Merry DE, Iñiguez-Lluhí JA, Lieberman AP.2015Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease. J Clin Invest. 125:831-845.
Cui S, Tanabe O, Sierant M, Shi L, Campbell A, Lim KC, Engel JD. 2015Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic ß-type globin genes. Blood. 125:1477-1487.
Fan J, Zeng H, Olson DP, Huber KM, Gibson JR, Takahashi JS.2015Vasoactive intestinal polypeptide (VIP)-expressing neurons in the suprachiasmatic nucleus provide sparse GABAergic outputs to local neurons with circadian regulation occurring distal to the opening of postsynaptic GABAA ionotropic receptors. J Neurosci. 35:1905-1920.
Feng Y, Sakamoto N, Wu R, Liu JY, Wiese A, Green ME, Green M, Akyol A, Roy BC, Zhai Y, Cho KR, Fearon ER.2015Tissue-Specific Effects of Reduced ?-catenin Expression on Adenomatous Polyposis Coli Mutation-Instigated Tumorigenesis in Mouse Colon and Ovarian Epithelium. PLoS Genet. 11:e1005638.
Furman M, Zhan Q, McCafferty C, Lerner BA, Motelow JE, Meng J, Ma C, Buchanan GF, Witten IB, Deisseroth K, Cardin JA, Blumenfeld H.2015Optogenetic stimulation of cholinergic brainstem neurons during focal limbic seizures: Effects on cortical physiology. Epilepsia.56:e198-202.
Gage PJ, Hurd EA, Martin DM.2015Mouse Models for the Dissection of CHD7 Functions in Eye Development and the Molecular Basis for Ocular Defects in CHARGE Syndrome. Invest Ophthalmol Vis Sci. 56:7923-7930.
Geister KA, Brinkmeier ML, Cheung LY, Wendt J, Oatley MJ, Burgess DL, Kozloff KM, Cavalcoli JD, Oatley JM, Camper SA.2015LINE-1 Mediated Insertion into Poc1a (Protein of Centriole 1 A) Causes Growth Insufficiency and Male Infertility in Mice. PLoS Genet. 11:e1005569.
Gergics P, Brinkmeier ML, Camper SA. 2015Lhx4 deficiency: increased cyclin dependent kinase inhibitor expression and pituitary hypoplasia. Mol Endocrinol. 29:597-612.
Grande MT, Sánchez-Laorden B, López-Blau C, De Frutos CA, Boutet A, Arévalo M, Rowe RG, Weiss SJ, López-Novoa JM, Nieto MA. 2015Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease. Nat Med. 21:989-997.
Hartlerode AJ, Morgan MJ, Wu Y, Buis J, Ferguson DO.2015Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors. Nat Struct Mol Biol. 22:736-743.
Higgins J, Brogley M, Palanisamy N, Mehra R, Ittmann MM, Li JZ, Tomlins SA, Robins DM.2015Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression. Horm Cancer. 6::67-86.
Hrycaj SM, Dye BR, Baker NC, Larsen BM, Burke AC, Spence JR, Wellik DM.2015Hox5 Genes Regulate the Wnt2/2b-Bmp4-Signaling Axis during Lung Development. Cell Rep. 12:903-912.
Inra CN, Zhou BO, Acar M, Murphy MM, Richardson J, Zhao Z, Morrison SJ. 2015A perisinusoidal niche for extramedullary haematopoiesis in the spleen. Nature. 527:466-471.
Jones M, Chase J, Brinkmeier M, Xu J, Weinberg DN, Schira J, Friedman A, Malek S, Grembecka J, Cierpicki T, Dou Y, Camper SA, Maillard I.2015Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells. J Clin Invest. 125:2007-2020.
Kikuchi, M., Wickman, L., Hodgin, J.B., Wiggins, R.C.2015Podometrics as a Potential Clinical Tool for Glomerular Disease Management. Semin Nephrol. 35:245-255.
Kommareddi P, Nair T, Kakaraparthi BN, Galano MM, Miller D, Laczkovich I, Thomas T, Lu L, Rule K, Kabara L, Kanicki A, Hughes ED, Jones JM, Hoenerhoff M, Fisher SG, Altschuler RA, Dolan D, Kohrman DC, Saunders TL, Carey TE.2015Hair Cell Loss, Spiral Ganglion Degeneration, and Progressive Sensorineural Hearing Loss in Mice with Targeted Deletion of Slc44a2/Ctl2. J Assoc Res Otolaryngol. [Epub ahead of print]
Lam DD, de Souza FS, Nasif S, Yamashita M, López-Leal R, Otero-Corchon V, Meece K, Sampath H, Mercer AJ, Wardlaw SL, Rubinstein M, Low MJ.2015Partially redundant enhancers cooperatively maintain Mammalian pomc expression above a critical functional threshold. PLoS Genet. 11:e1004935.
Lin X, O’Malley H, Chen C, Auerbach D, Foster M, Shekhar A, Zhang M, Coetzee W, Jalife J, Fishman GI, Isom L, Delmar M.2015Scn1b deletion leads to increased tetrodotoxin-sensitive sodium current, altered intracellular calcium homeostasis and arrhythmias in murine hearts. J Physiol. 593:13891407.
Lovat F, Fassan M, Gasparini P, Rizzotto L, Cascione L, Pizzi M, Vicentini C, Balatti V, Palmieri D, Costinean S, Croce CM.2015miR-15b/16-2 deletion promotes B-cell malignancies. Proc Natl Acad Sci U S A. 112:11636-11641.
Lubeck BA, Lapinski PE, Oliver JA, Ksionda O, Parada LF, Zhu Y, Maillard I, Chiang M, Roose J, King PD.2015Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia. J Immunol. 195:31-35.
Meng ZX, Wang L, Chang L, Sun J, Bao J, Li Y, Chen YE, Lin JD. 2015A Diet-Sensitive BAF60a-Mediated Pathway Links Hepatic Bile Acid Metabolism to Cholesterol Absorption and Atherosclerosis. Cell Rep. 13:1658-1669.
O’Malley HA, Isom LL.2015Annu Rev Physiol. 77:481-504.
Palmbos PL, Wang L, Yang H, Wang Y, Leflein J, Ahmet ML, Wilkinson JE, Kumar-Sinha C, Ney GM, Tomlins SA, Daignault S, Kunju LP, Wu XR, Lotan Y, Liebert M, Ljungman ME, Simeone DM. 2015ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms. Cancer Res. 75:5155-5166.
Patterson CM, Wong JM, Leinninger GM, Allison MB, Mabrouk OS, Kasper CL, Gonzalez IE, Mackenzie A, Jones JC, Kennedy RT, Myers MG Jr.2015Ventral tegmental area neurotensin signaling links the lateral hypothalamus to locomotor activity and striatal dopamine efflux in male mice. Endocrinology.156:1692-700.
Pinnell N, Yan R, Cho HJ, Keeley T, Murai MJ, Liu Y, Alarcon AS, Qin J, Wang Q, Kuick R, Elenitoba-Johnson KS, Maillard I, Samuelson LC, Cierpicki T, Chiang MY.2015The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia. Immunity. 43:870-883.
Pineault KM, Swinehart IT, Garthus KN, Ho E, Yao Q, Schipani E, Kozloff KM, Wellik DM.2015Hox11 genes regulate postnatal longitudinal bone growth and growth plate proliferation. Biol Open. 4:1538-1548.
Praggastis M, Tortelli B, Zhang J, Fujiwara H, Sidhu R, Chacko A, Chen Z, Chung C, Lieberman AP, Sikora J, Davidson C, Walkley SU, Pipalia NH, Maxfield FR, Schaffer JE, Ory DS. 2015A murine Niemann-Pick C1 I1061T knock-in model recapitulates the pathological features of the most prevalent human disease allele. J Neurosci. 35(21):8091-106.
Ramakrishnan SK, Anderson ER, Martin A, Centofanti B, Shah YM.2015Maternal intestinal HIF-2? is necessary for sensing iron demands of lactation in mice. Proc Natl Acad Sci U S A. 112:E3738-3747.
Ranghini EJ, Dressler GR. 2015vidence for intermediate mesoderm and kidney progenitor cell specification by Pax2 and PTIP dependent mechanisms. Dev Biol. 399:296-305.
Rusmini P, Polanco MJ, Cristofani R, Cicardi ME, Meroni M, Galbiati M, Piccolella M, Messi E, Giorgetti E, Lieberman AP, Milioto C, Rocchi A, Aggarwal T, Pennuto M, Crippa V, Poletti A. 2015Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy. Sci Rep. 5:15174.
Sa Q, Ochiai E, Tiwari A, Perkins S, Mullins J, Gehman M, Huckle W, Eyestone WH, Saunders TL, Shelton BJ, Suzuki Y. 2015Cutting Edge: IFN-gamma Produced by Brain-Resident Cells Is Crucial To Control Cerebral Infection with Toxoplasma gondii. J Immunol. 195:796-800.
Signore S, Sorrentino A, Borghetti G, Cannata A, Meo M, Zhou Y, Kannappan R, Pasqualini F, O’Malley H, Sundman M, Tsigkas N, Zhang E, Arranto C, Mangiaracina C, Isobe K, Sena BF, Kim J, Goichberg P, Nahrendorf M, Isom LL, Leri A, Anversa P, Rota M. 2015Late Na(+) current and protracted electrical recovery are critical determinants of the aging myopathy. Nat Commun. 6:8803.
Stinnett GS, Westphal NJ, Seasholtz AF.2015Pituitary CRH-binding protein and stress in female mice. Physiol Behav.150:16-23.
Sun Y, Oravecz-Wilson K, Mathewson N, Wang Y, McEachin R, Liu C, Toubai T, Wu J, Rossi C, Braun T, Saunders T, Reddy P.2015Mature T cell responses are controlled by microRNA-142. J Clin Invest. 125:2825-40.
Tan M, Li H, Sun Y.2015Inactivation of Sag/Rbx2/Roc2 e3 ubiquitin ligase triggers senescence and inhibits kras-induced immortalization. Neoplasia. 17:114-123.
Todisco A, Mao M, Keeley TM, Ye W, Samuelson LC, Eaton KA.2015Regulation of gastric epithelial cell homeostasis by gastrin and bone morphogenetic protein signaling. Physiol Rep. 3. e12501.
Vaccari I, Carbone A, Previtali SC, Mironova YA, Alberizzi V, Noseda R, Rivellini C, Bianchi F, Del Carro U, D’Antonio M, Lenk GM, Wrabetz L, Giger RJ, Meisler MH, Bolino A. 2015Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy. Hum Mol Genet. 24:383-396.
Verhaegen ME, Mangelberger D, Harms PW, Vozheiko TD, Weick JW, Wilbert DM, Saunders TL, Ermilov AN, Bichakjian CK, Johnson TM, Imperiale MJ, Dlugosz AA.2015Merkel Cell Polyomavirus Small T Antigen Is Oncogenic in Transgenic Mice. J Invest Dermatol. 135:1415-1424.
Verma R, Venkatareddy M, Kalinowski A, Patel SR, Salant DJ, Garg P. 2015Shp2 Associates with and Enhances Nephrin Tyrosine Phosphorylation and Is Necessary for Foot Process Spreading in Mouse Models of Podocyte Injury. Mol Cell Biol. 36:596-614.
Wagnon JL, Korn MJ, Parent R, Tarpey TA, Jones JM, Hammer MF, Murphy GG, Parent JM, Meisler MH. 2015Convulsive seizures and SUDEP in a mouse model of SCN8A epileptic encephalopathy. Hum Mol Genet. 24:506-15.
Wang H, Graham I, Hastings R, Gunewardena S, Brinkmeier ML, Conn PM, Camper SA, Kumar TR. 2015Gonadotrope-specific deletion of Dicer results in severely suppressed gonadotropins and fertility defects. J Biol Chem. 290:2699-2714.
Wang B, Li K, Wang A, Reiser M, Saunders T, Lockey RF, Wang JW. 2015Highly efficient CRISPR/HDR-mediated knock-in for mouse embryonic stem cells and zygotes. Biotechniques. 59:201-208
Wang L, Yang H, Abel EV, Ney GM, Palmbos PL, Bednar F, Zhang Y, Leflein J, Waghray M, Owens S, Wilkinson JE, Prasad J, Ljungman M, Rhim AD, Pasca di Magliano M, Simeone DM.2015ATDC induces an invasive switch in KRAS-induced pancreatic tumorigenesis. Genes Dev. 29:171-183.
Xia W, Quan T, Hammerberg C, Voorhees JJ, Fisher GJ. 2015A mouse model of skin aging: Fragmentation of dermal collagen fibrils and reduced fibroblast spreading due to expression of human matrix metalloproteinase-1. J Dermatol Sci. 78:79-82.
Xie CM, Wei D, Zhao L, Marchetto S, Mei L, Borg JP, Sun Y.2015Erbin is a novel substrate of the Sag-?TrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis. J Cell Biol. 209:721-737.
Xiang B, Zhang G, Ye S, Zhang R, Huang C, Liu J, Tao M, Ruan C, Smyth SS, Whiteheart SW, Li Z. 2015 Characterization of a Novel Integrin Binding Protein, VPS33B, Which Is Important for Platelet Activation and In Vivo Thrombosis and Hemostasis. Circulation. 132:2334-44.
Xie CM, Wei D, Zhao L, Marchetto S, Mei L, Borg JP, Sun Y. 2015Erbin is a novel substrate of the Sag-?TrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis. J Cell Biol. 209:7217-37.
Zhang J, Motyl KJ, Irwin R, MacDougald OA, Britton RA, McCabe LR. 2015Loss of Bone and Wnt10b Expression in Male Type 1 Diabetic Mice Is Blocked by the Probiotic Lactobacillus reuteri. Endocrinology. 156:3169-3182.
Adams EJ, Chen XW, O’Shea KS, Ginsburg D.2014Mammalian COPII coat component SEC24C is required for embryonic development in mice. J Biol Chem. 289(30):20858-70.
Airik R, Slaats GG, Guo Z, Weiss AC, Khan N, Ghosh A, Hurd TW, Bekker-Jensen S, Schrøder JM, Elledge SJ, Andersen JS, Kispert A, Castelli M, Boletta A, Giles RH, Hildebrandt F.2014Renal-retinal ciliopathy gene Sdccag8 regulates DNA damage response signaling. J Am Soc Nephrol. 25:2573-2583.
Baulac S, Lenk GM, Dufresnois B, Ouled Amar Bencheikh B, Couarch P, Renard J, Larson PA, Ferguson CJ, Noé E, Poirier K, Hubans C, Ferreira S, Guerrini R, Ouazzani R, El Hachimi KH, Meisler MH, Leguern E. 2014Role of the phosphoinositide phosphatase FIG4 gene in familial epilepsy with polymicrogyria. Neurology. 82:1068-1075.
Chen Z, Morris DL, Jiang L, Liu Y, Rui L.2014SH2B1 in β-cells regulates glucose metabolism by promoting β-cell survival and islet expansion. Diabetes. 63:585-595.
Chen Z, Morris DL, Jiang L, Liu Y, Rui L. 2014SH2B1 in β-cells promotes insulin expression and glucose metabolism in mice. Mol Endocrinol. 28:696-705.
Chua JP, Reddy SL, Merry DE, Adachi H, Katsuno M, Sobue G, Robins DM, Lieberman AP. 2014Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy. Hum Mol Genet. 23:1376-1386.
Contreras GA, Lee YH, Mottillo EP, Granneman JG.2014Inducible brown adipocytes in subcutaneous inguinal white fat: the role of continuous sympathetic stimulation. Am J Physiol Endocrinol Metab. 307:E793-799.
Dautan D, Huerta-Ocampo I, Witten IB, Deisseroth K, Bolam JP, Gerdjikov T, Mena-Segovia J.2014A major external source of cholinergic innervation of the striatum and nucleus accumbens originates in the brainstem. J Neurosci. 34:4509-18.
Everett LA, Cleuren AC, Khoriaty RN, Ginsburg D.2014Murine coagulation factor VIII is synthesized in endothelial cells. Blood. 123:3697-3705.
Flak JN, Patterson CM, Garfield AS, D’Agostino G, Goforth PB, Sutton AK, Malec PA, Wong JM, Germani M, Jones JC, Rajala M, Satin L, Rhodes CJ, Olson DP, Kennedy RT, Heisler LK, Myers MG Jr.2014Leptin-inhibited PBN neurons enhance responses to hypoglycemia in negative energy balance. Nat Neurosci. 17:1744-50.
Geister KA, Brinkmeier ML, Hsieh M, Faust SM, Karolyi IJ, Perosky JE, Kozloff KM, Conti M, Camper SA. 2014A novel loss-of-function mutation in Npr2 clarifies primary role in female reproduction and reveals a potential therapy for acromesomelic dysplasia, Maroteaux type. Hum Mol Genet. 22:345-357.
Goforth PB, Leinninger GM, Patterson CM, Satin LS, Myers MG Jr. 2014Leptin acts via lateral hypothalamic area neurotensin neurons to inhibit orexin neurons by multiple GABA-independent mechanisms. J Neurosci.; 34:11405-11415.
Guo S, Lim D, Dong Z, Saunders TL, Ma PX, Marcelo CL, Ritchie HH.2014Dentin Sialophosphoprotein: A Regulatory Protein for Dental Pulp Stem Cell Identity and Fate. Stem Cells Dev. 23:2883-2894
Hu Y, Xie Y, Wang Y, Chen X, Smith DE. 2014Development and Characterization of a Novel Mouse Line Humanized for the Intestinal Peptide Transporter PEPT1. Mol Pharm. 11:3737-3746.
Insolera R, Shao W, Airik R, Hildebrandt F, Shi SH.2014SDCCAG8 regulates pericentriolar material recruitment and neuronal migration in the developing cortex. Neuron. 83:805-22.
Jones JM, Meisler MH. 2014Modeling human epilepsy by TALEN targeting of mouse sodium channel Scn8a. Genesis. 52:141-148.
KC R, Srivastava A, Pomrenze MB, Millan EZ, Hopf FW, Keiflin R, Maiya R, Blasio A, Dadgar J, Kharazia V, De Guglielmo G, Crawford E, Janak PH, George O, Rice KC, Messing RO.2014A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits. Front Neurosci. 9:487.
Kehrl JM, Sahaya K, Dalton HM, Charbeneau RA, Kohut KT, Gilbert K, Pelz MC, Parent J, Neubig RR. 2014Gain-of-function mutation in Gnao1: A murine model of epileptiform encephalopathy (EIEE17)? Mamm Genome. 25:202-210.
Khoriaty R, Vasievich MP, Jones M, Everett L, Chase J, Tao J, Siemieniak D, Zhang B, Maillard I, Ginsburg D.2014Absence of a red blood cell phenotype in mice with hematopoietic deficiency of SEC23B. Mol Cell Biol. 34:3721-34.
Krebs CJ, Zhang D, Yin L, Robins DM. 2014The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis. Mol Cell Biol. 34:221-232.
Lee SH, Lee S, Yang H, Song S, Kim K, Saunders TL, Yoon JK, Koh GY, Kim I. 2014Notch pathway targets proangiogenic regulator Sox17 to restrict angiogenesis. Circ Res. 115:215-226.
Lenk GM, Meisler MH. 2014Mouse models of PI(3,5)P2 deficiency with impaired lysosome function. Methods Enzymol. 534:245-260.
Li H, Tan M, Jia L, Wei D, Zhao Y, Chen G, Xu J, Zhao L, Thomas D, Beer DG, Sun Y.2014Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis. J Clin Invest. 124:835-846.
Lieberman AP, Yu Z, Murray S, Peralta R, Low A, Guo S, Yu XX, Cortes CJ, Bennett CF, Monia BP, La Spada AR, Hung G. 2014Peripheral androgen receptor gene suppression rescues disease in mouse models of spinal and bulbar muscular atrophy. Cell Rep. 7:774-784.
Lin Y, Li XY, Willis AL, Liu C, Chen G, Weiss SJ.2014Snail1-dependent control of embryonic stem cell pluripotency and lineage commitment. Nat Commun. 5:3070.
Liu S, Sheng L, Miao H, Saunders TL, MacDougald OA, Koenig RJ, Xu B. 2014SRA gene knockout protects against diet-induced obesity and improves glucose tolerance. J Biol Chem. 289:13000-13009.
Lubeck BA, Lapinski PE, Bauler TJ, Oliver JA, Hughes ED, Saunders TL, King PD.2014Blood Vascular Abnormalities in Rasa1 R780Q Knockin Mice: Implications for the Pathogenesis of Capillary Malformation-Arteriovenous Malformation. Am J Pathol. 184:3163-3169.
McCutcheon JE, Cone JJ, Sinon CG, Fortin SM, Kantak PA, Witten IB, Deisseroth K, Stuber GD, Roitman MF.2014Optical suppression of drug-evoked phasic dopamine release. Front Neural Circuits. 2014 Sep 17;8:114.
Merchant JL, Saqui-Salces M.2014Inhibition of Hedgehog signaling in the gastrointestinal tract: targeting the cancer microenvironment. Cancer Treat Rev. 40:12-21.
Meng ZX, Wang L, Xiao Y, Lin JD.2014The Baf60c/Deptor Pathway Links Skeletal Muscle Inflammation to Glucose Homeostasis in Obesity. Diabetes. 63:1533-1545.
Mich JK, Signer RA, Nakada D, Pineda A, Burgess RJ, Vue TY, Johnson JE, Morrison SJ.2014Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. Elife. 3:e02669.
Micucci JA, Layman WS, Hurd EA, Sperry ED, Frank SF, Durham MA, Swiderski DL, Skidmore JM, Scacheri PC, Raphael Y, Martin DM.2014CHD7 and retinoic acid signaling cooperate to regulate neural stem cell and inner ear development in mouse models of CHARGE syndrome. Hum Mol Genet. 23:434-448.
Pei H, Sutton AK, Burnett KH, Fuller PM, Olson DP.2014AVP neurons in the paraventricular nucleus of the hypothalamus regulate feeding. Mol Metab. 3:209-215.
Rajala MW, Patterson CM, Opp JS, Foltin SK, Young VB, Myers MG Jr. 2014Leptin acts independently of food intake to modulate gut microbial composition in male mice. Endocrinology. 155:748-757.
Ramani B, Harris GM, Huang R, Seki T, Murphy GG, Costa MD, Fischer S, Saunders TL, Xia G, McEachin RC, Paulson HL. 2014A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript. Hum Mol Genet. 24:1211-1124.
Roger JE, Hiriyanna A, Gotoh N, Hao H, Cheng DF, Ratnapriya R, Kautzmann MA, Chang B, Swaroop A.2014OTX2 loss causes rod differentiation defect in CRX-associated congenital blindness. J Clin Invest. 124:631-643.
Rui L.2014 SH2B1 regulation of energy balance, body weight, and glucose metabolism. World J Diabetes. 5:511-526.
Saddoris MP, Sugam JA, Stuber GD, Witten IB, Deisseroth K, Carelli RM. 2014Mesolimbic dopamine dynamically tracks, and is causally linked to, discrete aspects of value-based decision making. Biol Psychiatry. 77:903-911.
Schneider BE, Behrends J, Hagens K, Harmel N, Shayman JA, Schaible UE.2014Lysosomal phospholipase A2: a novel player in host immunity to Mycobacterium tuberculosis. Eur J Immunol. 44:2394-2404.
Simonds SE, Pryor JT, Ravussin E, Greenway FL, Dileone R, Allen AM, Bassi J, Elmquist JK, Keogh JM, Henning E, Myers MG Jr, Licinio J, Brown RD, Enriori PJ, O’Rahilly S, Sternson SM, Grove KL, Spanswick DC, Farooqi IS, Cowley MA. 2014Leptin mediates the increase in blood pressure associated with obesity. Cell. 159:1404-1416.
Sperry ED, Hurd EA, Durham MA, Reamer EN, Stein AB, Martin DM. 2014 The chromatin remodeling protein CHD7, mutated in CHARGE syndrome, is necessary for proper craniofacial and tracheal development. Dev Dyn. 243:1055-1066.
Steinberg EE, Boivin JR, Saunders BT, Witten IB, Deisseroth K, Janak PH.2014Positive reinforcement mediated by midbrain dopamine neurons requires D1 and D2 receptor activation in the nucleus accumbens. PLoS One. 9:e94771.
Sutton AK, Pei H, Burnett KH, Myers MG Jr, Rhodes CJ, Olson DP.2014Control of food intake and energy expenditure by Nos1 neurons of the paraventricular hypothalamus. J Neurosci. 34:15306-18.
Tan M, Li H, Sun Y. 2014Endothelial deletion of Sag/Rbx2/Roc2 E3 ubiquitin ligase causes embryonic lethality and blocks tumor angiogenesis. Oncogene. 33:5211-5220.
Tian X, Kim JJ, Monkley SM, Gotoh N, Nandez R, Soda K, Inoue K, Balkin DM, Hassan H, Son SH, Lee Y, Moeckel G, Calderwood DA, Holzman LB, Critchley DR, Zent R, Reiser J, Ishibe S. 2014Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance. J Clin Invest. 2124:1098-1113.
Wagnon JL, Korn MJ, Parent R, Tarpey TA, Jones JM, Hammer MF, Murphy GG, Parent JM, Meisler MH. 2014Convulsive seizures and SUDEP in a mouse model of SCN8A epileptic encephalopathy. Hum Mol Genet. 24:506-515.
Wang SH, Fan Y, Baker JR Jr.2014Overexpression of BID in thyroids of transgenic mice increases sensitivity to iodine-induced autoimmune thyroiditis. J Transl Med. 12:180.
Watson CL, Mahe MM, Múnera J, Howell JC, Sundaram N, Poling HM, Schweitzer JI, Vallance JE, Mayhew CN, Sun Y, Grabowski G, Finkbeiner SR, Spence JR, Shroyer NF, Wells JM, Helmrath MA.2014An in vivo model of human small intestine using pluripotent stem cells. Nat Med. 20:1310-1314.
Wang GX, Zhao XY, Meng ZX, Kern M, Dietrich A, Chen Z, Cozacov Z, Zhou D, Okunade AL, Su X, Li S, Blüher M, Lin JD.2014The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis. Nat Med. 20:1436-1443.
Whiteman EL, Fan S, Harder JL, Walton KD, Liu CJ, Soofi A, Fogg VC, Hershenson MB, Dressler GR, Deutsch GH, Gumucio DL, Margolis B.2014Crumbs3 is essential for proper epithelial development and viability. Mol Cell Biol. 34:43-56.
Wu ZQ, Rowe RG, Lim KC, Lin Y, Willis A, Tang Y, Li XY, Nor JE, Maillard I, Weiss SJ. 2014A Snail1/Notch1 signalling axis controls embryonic vascular development. Nat Commun. 5:3998.
Yu L, Moriguchi T, Souma T, Takai J, Satoh H, Morito N, Engel JD, Yamamoto M. 2014GATA2 regulates body water homeostasis through maintaining aquaporin 2 expression in renal collecting ducts. Mol Cell Biol. 34:1929-41.
Zhao Y, Morgan MA, Sun Y.2014Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy. Antioxid Redox Signl .212383-2400
Abe A, Rzepecki PW, Shayman JA.2013A fluorogenic phospholipid for the detection of lysosomal phospholipase A2 activity. Anal Biochem. 434:78-83.
Baines AC, Adams EJ, Zhang B, Ginsburg D.2013Disruption of the Sec24d gene results in early embryonic lethality in the mouse. PLoS One. 8:e61114.
Brackenbury WJ, Yuan Y, O’Malley HA, Parent JM, Isom LL.2013Abnormal neuronal patterning occurs during early postnatal brain development of Scn1b-null mice and precedes hyperexcitability. Proc Natl Acad Sci U S A. 110:1089-1094
Broder C, Arnold P, Vadon-Le Goff S, Konerding MA, Bahr K, Müller S, Overall CM, Bond JS, Koudelka T, Tholey A, Hulmes DJ, Moali C, Becker-Pauly C. 2013Metalloproteases meprin alpha and meprin beta are C- and N-procollagen proteinases important for collagen assembly and tensile strength. Proc Natl Acad Sci U S A. 110:14219-14224.
Campeau PM, Lenk GM, Lu JT, Bae Y, Burrage L, Turnpenny P, Román Corona-Rivera J, Morandi L, Mora M, Reutter H, Vulto-van Silfhout AT, Faivre L, Haan E, Gibbs RA, Meisler MH, Lee BH2013Yunis-Varón syndrome is caused by mutations in FIG4, encoding a phosphoinositide phosphatase. Am J Hum Genet. 292:781-791.
Cannon JR, Geghman KD, Tapias V, Sew T, Dail MK, Li C, Greenamyre JT. 2013Expression of human E46K-mutated α-synuclein in BAC-transgenic rats replicates early-stage Parkinson’s disease features and enhances vulnerability to mitochondrial impairment. Exp Neurol. 240:44-56.
Chen XW, Wang H, Bajaj K, Zhang P, Meng ZX, Ma D, Bai Y, Liu HH, Adams E, Baines A, Yu G, Sartor MA, Zhang B, Yi Z, Lin J, Young SG, Schekman R, Ginsburg D.2013SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. Elife. 2:e00444.
Davis SW, Ellsworth BS, Peréz Millan MI, Gergics P, Schade V, Foyouzi N, Brinkmeier ML, Mortensen AH, Camper SA.2013Pituitary gland development and disease: from stem cell to hormone production. Curr Top Dev Biol. 106:1-47.
de Pater E, Kaimakis P, Vink CS, Yokomizo T, Yamada-Inagawa T, van der Linden R, Kartalaei PS, Camper SA, Speck N, Dzierzak E.2013Gata2 is required for HSC generation and survival. J Exp Med. 210:2843-2850.
Ding L, Morrison SJ.2013Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches. Ding L, Morrison SJ. Nature. 495:231-235.
Dunnick WA, Shi J, Fontaine C, Collins J T.2013Transgenes of the Mouse Immunoglobulin Heavy Chain Locus, Lacking Distal Elements in the 3’ Regulatory Region, are Impaired for Class Switch Recombination. PLoS ONE 8: e55842.
Dutton SB, Makinson CD, Papale LA, Shankar A, Balakrishnan B, Nakazawa K, Escayg A.2013Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility. Neurobiol Dis. 49:211-220.
Essien BE, Grasberger H, Romain RD, Law DJ, Veniaminova NA, Saqui-Salces M, El-Zaatari M, Tessier A, Hayes MM, Yang AC, Merchant JL.2013ZBP-89 regulates expression of tryptophan hydroxylase I and mucosal defense against Salmonella typhimurium in mice. Gastroenterology. 144:1466-1477.
Feng Y, Sentani K, Wiese A, Sands E, Green M, Bommer GT, Cho KR, Fearon ER. 2013 Sox9 induction, ectopic paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic apc inactivation. Am J Pathol. 183:493-503.
Geister KA, Brinkmeier ML, Hsieh M, Faust SM, Karolyi IJ, Perosky JE, Kozloff KM, Conti M, Camper SA. 2013A novel loss-of-function mutation in Npr2 clarifies primary role in female reproduction and reveals a potential therapy for acromesomelic dysplasia, Maroteaux type. Hum Mol Genet. 22:345-357
Harms KL, Dlugosz AA.2013Harnessing hedgehog for the treatment of basal cell carcinoma. JAMA Dermatol. 149:607-608.
Johnstone DB, Ikizler O, Zhang J, Holzman LB. 2013Background strain and the differential susceptibility of podocyte-specific deletion of Myh9 on murine models of experimental glomerulosclerosis and HIV nephropathy. PLoS One. 10;8(7):e67839.
Lehoczky JA, Thomas PE, Patrie KM, Owens KM, Villarreal LM, Galbraith K, Washburn J, Johnson CN, Gavino B, Borowsky AD, Millen KJ, Wakenight P, Law W, Van Keuren ML, Gavrilina G, Hughes ED, Saunders TL, Brihn L, Nadeau JH, Innis JW.2013A Novel Intergenic ETnII-β Insertion Mutation Causes Multiple Malformations in Polypodia Mice. PLoS Genet. 9(12):e1003967.
Li L, Khan N, Hurd T, Ghosh AK, Cheng C, Molday R, Heckenlively JR, Swaroop A, Khanna H.2013Ablation of the X-Linked Retinitis Pigmentosa 2 (Rp2) Gene in Mice Results in Opsin Mislocalization and Photoreceptor Degeneration. Invest Ophthalmol Vis Sci. 54:4503-4511.
Liu HX, Ermilov A, Grachtchouk M, Li L, Gumucio DL, Dlugosz AA, Mistretta CM. 2013Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance. Dev Biol. 382:82-97.
Meng ZX, Li S, Wang L, Ko HJ, Lee Y, Jung DY, Okutsu M, Yan Z, Kim JK, Lin JD.2013Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation. Nat Med. 19:640-645.
Ming X, Chew LJ, Gallo V.2013Transgenic overexpression of Sox17 promotes oligodendrocyte development and attenuates demyelination. J Neurosci. 33:12528-12542.
Nayak G, Lee SI, Yousaf R, Edelmann SE, Trincot C, Van Itallie CM, Sinha GP, Rafeeq M, Jones SM, Belyantseva IA, Anderson JM, Forge A, Frolenkov GI, Riazuddin S. 2013.2013Tricellulin deficiency affects tight junction architecture and cochlear hair cells. J Clin Invest. 123:4036-4049.
O’Brien JE, Meisler MH.2013Sodium channel SCN8A (Nav1.6): properties and de novo mutations in epileptic encephalopathy and intellectual disability. Front Genet. 4:213.
Paduraru C, Bezbradica JS, Kunte A, Kelly R, Shayman JA, Veerapen N, Cox LR, Besra GS, Cresswell P.2013Role for lysosomal phospholipase A2 in iNKT cell-mediated CD1d recognition. Proc Natl Acad Sci U S A. 110:5097-5102.
Pérez-Millán MI, Zeidler MG, Saunders TL, Camper SA, Davis SW.2013Efficient, specific, developmentally appropriate cre-mediated recombination in anterior pituitary gonadotropes and thyrotropes. Genesis. 51:785-792.
Rabionet M, Bayerle A, Marsching C, Jennemann R, Gröne HJ, Yildiz Y, Wachten D, Shaw W, Shayman JA, Sandhoff R.20131-O-acylceramides are natural components of human and mouse epidermis. J Lipid Res. 54:3312-3321.
Regal JA, Festerling TA, Buis JM, Ferguson DO.2013Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms. Hum Mol Genet. 22:5146-5159
Reifler A, Lenk GM, Li X, Groom L, Brooks SV, Wilson D, Bowerson M, Dirksen RT, Meisler MH, Dowling JJ.2013Murine Fig4 is dispensable for muscle development but required for muscle function. Skelet Muscle. 3:21.
Schwab KR, Smith GD, Dressler GR. 2013Arrested spermatogenesis and evidence for DNA damage in PTIP mutant testes. Dev Biol. 373:64-71.
Sheng L, Liu Y, Jiang L, Chen Z, Zhou Y, Cho KW, Rui L. 2013Hepatic SH2B1 and SH2B2 regulate liver lipid metabolism and VLDL secretion in mice. PLoS One. 8:e83269.
Soofi A, Zhang P, Dressler GR. 2013Kielin/chordin-like protein attenuates both acute and chronic renal injury. J Am Soc Nephrol. 224:897-905.
Steinberg EE, Keiflin R, Boivin JR, Witten IB, Deisseroth K, Janak PH. 2013A causal link between prediction errors, dopamine neurons and learning. Nat Neurosci.16:966-73.
Strickland FM, Hewagama A, Wu A, Sawalha AH, Delaney C, Hoeltzel MF, Yung R, Johnson K, Mickelson B, Richardson BC.2013Diet influences expression of autoimmune-associated genes and disease severity by epigenetic mechanisms in a transgenic mouse model of lupus. Arthritis Rheum. 65:1872-1881.
Tang Y, Rowe RG, Botvinick EL, Kurup A, Putnam AJ, Seiki M, Weaver VM, Keller ET, Goldstein S, Dai J, Begun D, Saunders T, Weiss S2013MT1-MMP-Dependent Control of Skeletal Stem Cell Commitment via a β1-Integrin/YAP/TAZ Signaling Axis. Dev Cell. 25:402-416.
Ting JT, Feng G.2013Development of transgenic animals for optogenetic manipulation of mammalian nervous system function: progress and prospects for behavioral neuroscience. Behav Brain Res. 255:3-18.
Tye KM, Mirzabekov JJ, Warden MR, Ferenczi EA, Tsai HC, Finkelstein J, Kim SY, Adhikari A, Thompson KR, Andalman AS, Gunaydin LA, Witten IB, Deisseroth K. 2013Dopamine neurons modulate neural encoding and expression of depression-related behaviour. Nature. 493:537-541.
Waite MR, Skidmore JM, Micucci JA, Shiratori H, Hamada H, Martin JF, Martin DM.2013Pleiotropic and isoform-specific functions for Pitx2 in superior colliculus and hypothalamic neuronal development. Mol Cell Neurosci. 52:128-39.
Wiese CB, Fleming N, Buehler DP, Southard-Smith EM.2013A Uchl1-Histone2BmCherry:GFP-gpi BAC transgene for imaging neuronal progenitors. Genesis. 51:852-861.
Worthington JJ, Samuelson LC, Grencis RK, McLaughlin JT.2013Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion. PLoS Pathog. 9(1):e1003122.
Wright J, Wang X, Haataja L, Kellogg AP, Lee J, Liu M, Arvan P.2013Dominant protein interactions that influence the pathogenesis of conformational diseases. J Clin Invest. 123: 3124-3134.
Wood MA, Acharya A, Finco I, Swonger JM, Elston MJ, Tallquist MD, Hammer GD. 2013Fetal adrenal capsular cells serve as progenitor cells for steroidogenic and stromal adrenocortical cell lineages in M. musculus. Development. 140:4522-4532.
Xu Y, Kim ER, Zhao R, Myers MG Jr, Munzberg H, Tong Q. 2013Glutamate release mediates leptin action on energy expenditure. Mol Metab. 2:109-115.
Xu J, Morris L, Thapa A, Ma H, Michalakis S, Biel M, Baehr W, Peshenko IV, Dizhoor AM, Ding XQ. 2013cGMP Accumulation Causes Photoreceptor Degeneration in CNG Channel Deficiency: Evidence of cGMP Cytotoxicity Independently of Enhanced CNG Channel Function. J Neurosci. 33:14939-14948.
Xue X, Ramakrishnan S, Anderson E, Taylor M, Zimmermann EM, Spence JR, Huang S, Greenson JK, Shah YM.2013Endothelial PAS Domain Protein 1 Activates the Inflammatory Response in the Intestinal Epithelium to Promote Colitis in Mice. Gastroenterology. 145:831-841.
Yu T, Lieberman AP.2013Npc1 acting in neurons and glia is essential for the formation and maintenance of CNS myelin. PLoS Genet. 9:e1003462.
Zhou W, Wei W, Sun Y.2013Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases. Cell Res. 23:599-619.
Akhmetshina A, Palumbo K, Dees C, Bergmann C, Venalis P, Zerr P, Horn A, Kireva T, Beyer C, Zwerina J, Schneider H, Sadowski A, Riener MO, MacDougald OA, Distler O, Schett G, Distler JH.2012Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis. Nat Commun. 13;3:735.
Blij S, Frum T, Akyol A, Fearon E, Ralston A.2012Maternal Cdx2 is dispensable for mouse development. Development. 139:3969-3972.
Blumer JB, Oner SS, Lanier SM.2012Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif. Acta Physiol (Oxf) 204:202-218.
Buis J, Stoneham T, Spehalski E, Ferguson DO. 2012Mre11 regulates CtIP-dependent double-strand break repair by interaction with CDK2. Nat Struct Mol Biol. 19:246-252.
Burrows PE, Gonzalez-Garay ML, Rasmussen JC, Aldrich MB, Guilliod R, Maus EA, Fife CE, Kwon S, Lapinski PE, King PD, Sevick-Muraca EM. 2012Lymphatic abnormalities are associated with RASA1 gene mutations in mouse and man. Proc Natl Acad Sci U S A. 110:8621-8626.
Cho H, Kamenyeva O, Yung S, Gao JL, Hwang IY, Park C, Murphy PM, Neubig RR, Kehrl JH.2012The Loss of RGS Protein-Gαi2 Interactions Results in Markedly Impaired Mouse Neutrophil Trafficking to Inflammatory Sites. Mol Cell Biol. 32:4561-4571.
Ding L, Saunders TL, Enikolopov G, Morrison SJ.2012Endothelial and perivascular cells maintain haematopoietic stem cells. Nature. 481:457-462.
Eberl M, Klingler S, Mangelberger D, Loipetzberger A, Damhofer H, Zoidl K, Schnidar H, Hache H, Bauer HC, Solca F, Hauser-Kronberger C, Ermilov AN, Verhaegen ME, Bichakjian CK, Dlugosz AA, Nietfeld W, Sibilia M, Lehrach H, Wierling C, Aberger F.2012Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells. EMBO Mol Med. 4:218-233. 
El-Zaatari M, Kao JY, Tessier A, Bai L, Hayes MM, Fontaine C, Eaton KA, Merchant JL. 2012Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets. PLoS One. 8(3):e58935
Emmett LS, O’Shea KS.2012Geminin is required for epithelial to mesenchymal transition at gastrulation. Stem Cells Dev. 21:2395-2409.
Essien BE, Grasberger H, Romain RD, Law DJ, Veniaminova NA, Saqui-Salces M, El-Zaatari M, Tessier A, Hayes MM, Yang AC, Merchant JL. 2012ZBP-89 regulates expression of tryptophan hydroxylase I and mucosal defense against Salmonella typhimurium in mice. Gastroenterology. 144:1466-1477.
Fang Q, Giordimaina AM, Dolan DF, Camper SA, Mustapha M.2012Genetic background of Prop1(df) mutants provides remarkable protection against hypothyroidism-induced hearing impairment. J Assoc Res Otolaryngol. 13:173-184.
Ferguson CJ, Lenk GM, Jones JM, Grant AE, Winters JJ, Dowling JJ, Giger RJ, Meisler MH. 2012Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration. Hum Mol Genet. 21:3525-3534.
Fukuda A, Chowdhury MA, Venkatareddy MP, Wang SQ, Nishizono R, Suzuki T, Wickman LT, Wiggins JE, Muchayi T, Fingar D, Shedden KA, Inoki K, Wiggins RC.2012Growth-dependent podocyte failure causes glomerulosclerosis. J Am Soc Nephrol. 23:1351-1363.
Fukuda A, Wickman LT, Venkatareddy MP, Sato Y, Chowdhury MA, Wang SQ, Shedden KA, Dysko RC, Wiggins JE, Wiggins RC. Kidney Int.2012Angiotensin II-dependent persistent podocyte loss from destabilized glomeruli causes progression of end stage kidney disease. 81:40-55.
Fukuda A, Wickman LT, Venkatareddy MP, Wang SQ, Chowdhury MA, Wiggins JE, Shedden KA, Wiggins RC.2012Urine podocin:nephrin mRNA ratio (PNR) as a podocyte stress biomarker. Nephrol Dial Transplant. 27:4079-4087.
Gopalakrishnan K, Kumarasamy S, Abdul-Majeed S, Kalinoski AL, Morgan EE, Gohara AF, Nauli SM, Filipiak WE, Saunders TL, Joe B. 2012Targeted disruption of Adamts16 gene in a rat genetic model of hypertension.  Proc Natl Acad Sci U S A. 109:20555-20559.
Hurd EA, Micucci JA, Reamer EN, Martin DM.2012Delayed fusion and altered gene expression contribute to semicircular canal defects in Chd7 deficient mice. Mech Dev. 129:308-323.
Hüttemann M, Klewer S, Lee I, Pecinova A, Pecina P, Liu J, Lee M, Doan JW, Larson D, Slack E, Maghsoodi B, Erickson RP, Grossman LI.2012Mice deleted for heart-type cytochrome c oxidase subunit 7a1 develop dilated cardiomyopathy. Mitochondrion.12:294-304.
Hsu SH, Wang B, Kota J, Yu J, Costinean S, Kutay H, Yu L, Bai S, La Perle K, Chivukula RR, Mao H, Wei M, Clark KR, Mendell JR, Caligiuri MA, Jacob ST, Mendell JT, Ghoshal K.2012Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. J Clin Invest. 122:2871-2883.
Kaur K, Parra S, Chen R, Charbeneau RA, Wade SM, Jay PY, Neubig RR.2012Gαi2 signaling: friend or foe in cardiac injury and heart failure? Naunyn Schmiedebergs Arch Pharmacol. 385:443-453.
Kenneth NS, Younger JM, Hughes ED, Marcotte D, Barker PA, Saunders TL, Duckett CS.2012An Inactivating Caspase-11 Passenger Mutation Originating from the 129 Murine Strain in Mice Targeted for c-Iap1. Biochem J. 443:355-359.
Khoriaty R, Vasievich MP, Ginsburg D.2012The COPII pathway and hematologic disease. Blood. 120:31-38.
King PD, Lubeck BA, Lapinski PE. 2012Nonredundant functions for Ras GTPase-activating proteins in tissue homeostasis. Sci Signal. 6:re1. 
Krebs CJ, Schultz DC, Robins DM. 2012The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration. Mol Cell Biol. 32:3732-3742.
Kwon M, Pavlov TS, Nozu K, Rasmussen SA, Ilatovskaya DV, Lerch-Gaggl A, North LM, Kim H, Qian F, Sweeney WE Jr, Avner ED, Blumer JB, Staruschenko A, Park F. 2012G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease. Proc Natl Acad Sci U S A. 109:21462-21467.
Lapinski PE, Kwon S, Lubeck BA, Wilkinson JE, Srinivasan RS, Sevick-Muraca E, King PD. 2012RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice. J Clin Invest. 122:733-747.
Leshan RL, Greenwald-Yarnell M, Patterson CM, Gonzalez IE, Myers MG Jr. 2012Leptin action through hypothalamic nitric oxide synthase-1-expressing neurons controls energy balance. Nat Med. 18:820-823.
Li X, Li L, Pandey R, Byun JS, Gardner K, Qin Z, Dou Y.2012The histone acetyltransferase MOF is a key regulator of the embryonic stem cell core transcriptional network. Cell Stem Cell. 11:163-178.
Li P, Neubig RR, Zingarelli B, Borg K, Halushka PV, Cook JA, Fan H. 2012Toll-like Receptor-Induced Inflammatory Cytokines are Suppressed by Gain of Function or Overexpression of Gα (i2) Protein. Inflammation. 35:1611-1617.
Lim KC, Hosoya T, Brandt W, Ku CJ, Hosoya-Ohmura S, Camper SA, Yamamoto M, Engel JD.2012Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning. J Clin Invest. 122:3705-3717.
Liu Z, Demitrack ES, Keeley TM, Eaton KA, El-Zaatari M, Merchant JL, Samuelson LC. 2012IFNγ contributes to the development of gastric epithelial cell metaplasia in Huntingtin interacting protein 1 related (Hip1r)-deficient mice. Lab Invest. 92:1045-1057. 
Miller SJ, Heist KA, Feng Y, Galbán CJ, Rehemtulla A, Ross BD, Fearon ER, Wang TD.2012Multimodal imaging of growth and rapamycin-induced regression of colonic adenomas in apc mutation-dependent mouse. Transl Oncol. 5:313-320.
Marionneau C, Carrasquillo Y, Norris AJ, Townsend RR, Isom LL, Link AJ, Nerbonne JM. 2012The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K+ channels. J Neurosci. 32:5716-5727.
Myers MG Jr, Olson DP. 2012Central nervous system control of metabolism. Nature. 491:357-363.
Patterson CM, Villanueva EC, Greenwald-Yarnell M, Rajala M, Gonzalez IE, Saini N, Jones J, Myers MG Jr. 2012Leptin action via LepR-b Tyr1077 contributes to the control of energy balance and female reproduction. Mol Metab. 1:61-69.
Prasov L, Nagy M, Rudolph DD, Glaser T.2012Math5 (Atoh7) gene dosage limits retinal ganglion cell genesis. Neuroreport. 23:631-634.
Richardson B, Sawalha AH, Ray D, Yung R.2012Murine models of lupus induced by hypomethylated T cells (DNA hypomethylation and lupus…). Methods Mol Biol. 900:169-180.
Roger JE, Ranganath K, Zhao L, Cojocaru RI, Brooks M, Gotoh N, Veleri S, Hiriyanna A, Rachel RA, Campos MM, Fariss RN, Wong WT, Swaroop A. 2012Preservation of cone photoreceptors after a rapid yet transient degeneration and remodeling in cone-only Nrl-/- mouse retina. J Neurosci. 32:528-541.
Uebachs M, Albus C, Opitz T, Isom L, Niespodziany I, Wolff C, Beck H. 2012Loss of ß1 accessory Na+ channel subunits causes failure of carbamazepine, but not of lacosamide, in blocking high-frequency firing via differential effects on persistent Na+ currents. Epilepsia. 53:1959-1967.
Qiao Y, Zhu L, Sofi H, Lapinski PE, Horai R, Mueller K, Stritesky GL, He X, Teh HS, Wiest DL, Kappes DJ, King PD, Hogquist KA, Schwartzberg PL, Sant’Angelo DB, Chang CH.2012Development of promyelocytic leukemia zinc finger-expressing innate CD4 T cells requires stronger T-cell receptor signals than conventional CD4 T cells. Proc Natl Acad Sci U S A.109:16264-16269.
Rother E, Belgardt BF, Tsaousidou E, Hampel B, Waisman A, Myers MG Jr, Brüning JC. 2012Acute selective ablation of rat insulin promoter-expressing (RIPHER) neurons defines their orexigenic nature. Proc Natl Acad Sci U S A. 109):18132-18137.
Rousso DL, Pearson CA, Gaber ZB, Miquelajauregui A, Li S, Portera-Cailliau C, Morrisey EE, Novitch BG. 2012Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS. Neuron. 74:314-30. PubMed PMID: 22542185
Sadagurski M, Leshan RL, Patterson C, Rozzo A, Kuznetsova A, Skorupski J, Jones JC, Depinho RA, Myers MG Jr, White MF. 2012IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action. Cell Metab. 15:703-712.
Saqui-Salces M, Covés-Datson E, Veniaminova NA, Waghray M, Syu LJ, Dlugosz AA, Merchant JL. 2012Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia. PLoS One.7(10):e48039.
Sevick-Muraca EM, King PD. 2012Lymphatic vessel abnormalities arising from disorders of Ras signal transduction. Trends Cardiovasc Med. 2013 Oct 31. [Epub ahead of print]
Schumacher MA, Donnelly JM, Engevik AC, Xiao C, Yang L, Kenny S, Varro A, Hollande F, Samuelson LC, Zavros Y. 2012Gastric Sonic Hedgehog acts as a macrophage chemoattractant during the immune response to Helicobacter pylori. Gastroenterology. 142:1150-1159.
Skidmore JM, Waite MR, Alvarez-Bolado G, Puelles L, Martin DM. 2012A novel TaulacZ allele reveals a requirement for Pitx2 in formation of the mammillothalamic tract. Genesis. 50:67-73.
Soofi A, Levitan I, Dressler GR. 2012Two novel EGFP insertion alleles reveal unique aspects of Pax2 function in embryonic and adult kidneys. Dev Biol. 36: 241-250.
Spehalski E, Kovalchuk AL, Collins JT, Liang G, Dubois W, Morse HC 3rd, Ferguson DO, Casellas R, Dunnick WA. 2012Oncogenic Myc translocations are independent of chromosomal location and orientation of the immunoglobulin heavy chain locus. Proc Natl Acad Sci U S A. 109:13716-13721.
Strickland FM, Hewagama A, Lu Q, Wu A, Hinderer R, Webb R, Johnson K, Sawalha AH, Delaney C, Yung R, Richardson BC. 2012Environmental exposure, estrogen and two X chromosomes are required for disease development in an epigenetic model of lupus. J Autoimmun. 38:J135-143.
Sun H, Xu Y, Sitkiewicz I, Ma Y, Wang X, Yestrepsky BD, Huang Y, Lapadatescu MC, Larsen MJ, Larsen SD, Musser JM, Ginsburg D.2012Inhibitor of streptokinase gene expression improves survival after group A streptococcus infection in mice. Proc Natl Acad Sci U S A 109:3469-3474.
Syu LJ, El-Zaatari M, Eaton KA, Liu Z, Tetarbe M, Keeley TM, Pero J, Ferris J, Wilbert D, Kaatz A, Zheng X, Qiao X, Grachtchouk M, Gumucio DL, Merchant JL, Samuelson LC, Dlugosz AA.2012Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia. Am J Pathol. 181:2114-2125.
Tao J, Zhu M, Wang H, Afelik S, Vasievich MP, Chen XW, Zhu G, Jensen J, Ginsburg D, Zhang B. 2012SEC23B is required for the maintenance of murine professional secretory tissues. Proc Natl Acad Sci U S A. 109:E2001-2009.
Veniaminova NA, Hayes MM, Varney JM, Merchant JL.2012Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia. Am J Physiol Gastrointest Liver Physiol. 303:G752-G764.
Warren SA, Briggs LE, Zeng H, Chuang J, Chang EI, Terada R, Li M, Swanson MS, Lecker SH, Willis MS, Spinale FG, Maupin-Furlowe J, McMullen JR, Moss RL, Kasahara H. 2012Myosin light chain phosphorylation is critical for adaptation to cardiac stress. Circulation. 126:2575-2588.
Wei Q, Fentress HM, Hoversten MT, Zhang L, Hebda-Bauer EK, Watson SJ, Seasholtz AF, Akil H. 2012Early-Life Forebrain Glucocorticoid Receptor Overexpression Increases Anxiety Behavior and Cocaine Sensitization. Biol Psychiatry. 71:224-31.
Wu J, Liu C, Chen J, Yu X.2012RAP80 protein is important for genomic stability and is required for stabilizing BRCA1-A complex at DNA damage sites in vivo. J Biol Chem. 287:22919-22926.
Wu X, Peppi M, Vengalil MJ, Maheras KJ, Southwood CM, Bradley M, Gow A.2012Transgene-mediated rescue of spermatogenesis in Cldn11-null mice. Biol Reprod. 86: 1-11.
Xiao H, Yu Z, Wu Y, Nan J, Merry DE, Sekiguchi JM, Ferguson DO, Lieberman AP, Dressler GR. 2012A polyglutamine expansion disease protein sequesters PTIP to attenuate DNA repair and increase genomic instability. Hum Mol Genet. 21:4225-4236.
Xu Y, O’Brien WG 3rd, Lee CC, Myers MG Jr, Tong Q.2012Role of GABA release from leptin receptor-expressing neurons in body weight regulation. Endocrinology. 153:2223-2233.
Yu S, Zhou X, Hsiao JJ, Yu D, Saunders TL, Xue HH.2012Fidelity of a BAC-EGFP transgene in reporting dynamic expression of IL-7Rα in T cells. Transgenic Res.21:201-15.
Yin KJ, Olsen K, Hamblin M, Zhang J, Schwendeman SP, Chen YE. 2012Vascular endothelial cell-specific microRNA-15a inhibits angiogenesis in hindlimb ischemia. J Biol Chem. 287:27055-27064.
Zhang Y, McCartney AJ, Zolov SN, Ferguson CJ, Meisler MH, Sutton MA, Weisman LS. 2012Modulation of synaptic function by VAC14, a protein that regulates the phosphoinositides PI(3,5)P? and PI(5)P. EMBO J. 31:3442-3456.
Zolov SN, Bridges D, Zhang Y, Lee WW, Riehle E, Verma R, Lenk GM, Converso-Baran K, Weide T, Albin RL, Saltiel AR, Meisler MH, Russell MW, Weisman LS. 2012In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P. Proc Natl Acad Sci U S A. 109:17472-17477.
Desai MM, Tumurbataar B, Zhang Y, Chan LN, Sun J, Chan TS.2011Aberrant transcription and post-transcriptional processing of hepatitis C virus non-structural genes in transgenic mice.
Transgenic Res. 2011 Dec;20(6):1273-84. doi: 10.1007/s11248-011-9494-x. Epub 2011 Feb 24. PMID: 21347690
Barthson J, Germano CM, Moore F, Maida A, Drucker DJ, Marchetti P, Gysemans C, Mathieu C, Nuñez G, Jurisicova A, Eizirik DL, Gurzov EN.2011Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activation. J Biol Chem. 286:39632-39643.
Castinetti F, Brinkmeier ML, Gordon DF, Vella KR, Kerr JM, Mortensen AH, Hollenberg A, Brue T, Ridgway EC, Camper SA.2011PITX2 AND PITX1 Regulate Thyrotroph Function and Response to Hypothyroidism. Mol Endocrinol.25:1950-1960.
Cho KW, Zhou Y, Sheng L, Rui L. 2011Lipocalin-13 Regulates Glucose Metabolism by Both Insulin-dependent and Insulin-independent Mechanisms. Mol Cell Biol. 31:450-457.
Choi BY, Kim HM, Ito T, Lee KY, Li X, Monahan K, Wen Y, Wilson E, Kurima K, Saunders TL, Petralia RS, Wangemann P, Friedman TB, Griffith AJ. 2011Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisition. J Clin Invest. 121:4516-4525. 
Clement LC, Avila-Casado C, Macé C, Soria E, Bakker WW, Kersten S, Chugh SS.2011Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. Nat Med. 17:117-122.
Dobson ME, Diallo-Krou E, Grachtchouk V, Yu J, Colby LA, Wilkinson JE, Giordano TJ, Koenig RJ2011Pioglitazone induces a proadipogenic antitumor response in mice with PAX8-PPARgamma fusion protein thyroid carcinoma. Endocrinology. 152:4455-4465.
Dunnick WA, Shi J, Holden V, Fontaine C, Collins JT.2011The role of germline promoters and I exons in cytokine-induced gene-specific class switch recombination. J Immunol. 186:350-358. 
Dunnick WA, Shi J, Zerbato JM, Fontaine CA, Collins JT. 2011Enhancement of antibody class-switch recombination by the cumulative activity of four separate elements. J Immunol. 187:4733-4743.
Corpening JC, Deal KK, Cantrell VA, Skelton SB, Buehler DP, Southard-Smith EM.2011Isolation and live imaging of enteric progenitors based on Sox10-histone2bvenus transgene expression. Genesis. 49: 599-618.
Garg P, Rabelink T. 2011Glomerular proteinuria: a complex interplay between unique players. 2011. Adv Chronic Kidney Dis. 18:233-42.
Ghiasvand NM, Rudolph DD, Mashayekhi M, Brzezinski JA 4th, Goldman D, Glaser T.2011Deletion of a remote enhancer near ATOH7 disrupts retinal neurogenesis, causing NCRNA disease. Nat Neurosci. 14:578-586
Grachtchouk M, Pero J, Yang SH, Ermilov AN, Michael LE, Wang A, Wilbert D, Patel RM, Ferris J, Diener J, Allen M, Lim S, Syu LJ, Verhaegen M, Dlugosz AA. 2011Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations. J Clin Invest. 121:1768-81.
Inoki K, Mori H, Wang J, Suzuki T, Hong S, Yoshida S, Blattner SM, Ikenoue T, Rüegg MA, Hall MN, Kwiatkowski DJ, Rastaldi MP, Huber TB, Kretzler M, Holzman LB, Wiggins RC, Guan KL. 2011mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. J Clin Invest. 1212181-96.
Hodish I, Absood A, Liu L, Liu M, Haataja L, Larkin D, Al-Khafaji A, Zaki A, Arvan P. 2011In vivo misfolding of proinsulin below the threshold of frank diabetes. Diabetes.60:2092-2101.
Johnson GD, Platts AE, Lalancette C, Goodrich R, Heng HH, Krawetz SA.2011Interrogating the transgenic genome: development of an interspecies tiling array. Syst Biol Reprod Med. 57:54-62.
Johnstone DB, Zhang J, George B, Léon C, Gachet C, Wong H, Parekh R, Holzman LB.2011Podocyte-specific deletion of Myh9 encoding non-muscle myosin heavy chain 2A predisposes mice to glomerulopathy. Mol Cell Biol. 31:2162-2170.
Jorge BS, Campbell CM, Miller AR, Rutter ED, Gurnett CA,Vanoye CG, George AL, Jr, Kearney JA. 2011Voltage-gated potassium channel KCNV2 (Kv8.2) contributes to epilepsy usceptibility. Proc Natl Acad Sci U S A. 108:5443-5448.
Kaur K, Kehrl JM, Charbeneau RA, Neubig RR.2011RGS-Insensitive Gα Subunits: Probes of Gα Subtype-Selective Signaling and Physiological Functions of RGS Proteins. Methods Mol Biol.756:75-98.
Kawashima Y, Géléoc GS, Kurima K, Labay V, Lelli A, Asai Y, Makishima T, Wu DK, Della Santina CC, Holt JR, Griffith AJ. 2011Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes. J Clin Invest. 121:4796-4809.
Kurima K, Hertzano R, Gavrilova O, Monahan K, Shpargel KB, Nadaraja G, Kawashima Y, Lee KY, Ito T, Higashi Y, Eisenman DJ, Strome SE, Griffith AJ. 2011A Noncoding Point Mutation of Zeb1 Causes Multiple Developmental Malformations and Obesity in Twirler Mice. PLoS Genetics. 7(9):e1002307.
Lapinski PE, Qiao Y, Chang CH, King PD2011A role for p120 RasGAP in thymocyte positive selection and survival of naive T cells. J Immunol. 187:151-163.
Layman WS, Hurd EA, Martin DM.2011Reproductive dysfunction and decreased GnRH neurogenesis in a mouse model of CHARGE syndrome. Hum Mol Genet. 20:3138-1350
Leinninger GM, Opland DM, Jo YH, Faouzi M, Christensen L, Cappellucci LA, Rhodes CJ, Gnegy ME, Becker JB, Pothos EN, Seasholtz AF, Thompson RC, Myers MG Jr.2011Leptin Action via Neurotensin Neurons Controls Orexin, the Mesolimbic Dopamine System and Energy Balance. Cell Metab. 14:313-323.
Li X, Li L, Pandey R, Byun JS, Gardner K, Qin Z, Dou Y. 2011The Histone Acetyltransferase MOF Is a Key Regulator of the Embryonic Stem Cell Core Transcriptional Network.Cell Stem Cell. 11:163-178. 
Lopez-Santiago LF, Brackenbury WJ, Chen C, Isom LL.2011 Na+ channel SCN1B regulates dorsal root ganglion nociceptor excitability in vivo. J Biol Chem. 286:22913-22923.
Ma T, Keller JA, Yu X. 2011. RNF8-dependent histone ubiquitination during DNA damage response and spermatogenesis. Acta Biochim Biophys Sin (Shanghai). 43:339-345.
McCormick JA, Nelson JH, Yang CL, Curry JN, Ellison DH. 2011Overexpression of the sodium chloride cotransporter is not sufficient to cause familial hyperkalemic hypertension. Hypertension. 58:888-894.
Mendez MP, Monroy YK, Du M, Preston AM, Tolle L, Lin Y, VanDussen KL, Samuelson LC, Standiford TJ, Curtis JL, Beck JM, Christensen PJ, Paine R 3rd. 2011Overexpression of sICAM-1 in the alveolar epithelial space results in an exaggerated inflammatory response and early death in Gram negative pneumonia. Respir Res. 12:12.
Miller SJ, Joshi BP, Feng Y, Gaustad A, Fearon ER, Wang TD.2011In vivo fluorescence-based endoscopic detection of colon dysplasia in the mouse using a novel Peptide probe. PLoS One. 6:e17384.
Nasonkin IO, Ward RD, Bavers DL, Beuschlein F, Mortensen AH, Keegan CE, Hammer GD, Camper SA. 2011Aged PROP1 deficient dwarf mice maintain ACTH production. PLoS One. 6:e28355.
Patino GA, Brackenbury WJ, Bao Y, Lopez-Santiago LF, O’Malley HA, Chen C, Calhoun JD, Lafrenière RG, Cossette P, Rouleau GA, Isom LL.2011Voltage-gated Na+ channel β1B: a secreted cell adhesion molecule involved in human epilepsy. J Neurosci. 31:14577-14591.
Pipe SW, Miao H, Butler SP, Calcaterra J, Velander WH.2011Functional factor VIII made with von Willebrand factor at high levels in transgenic milk. J Thromb Haemost. 9:2235-2242.
Qiao XT, Gumucio DL. 2011Current molecular markers for gastric progenitor cells and gastric cancer stem cells. J Gastroenterol. 46:855-865.
Regner KR, Nozu K, Lanier SM, Blumer JB, Avner ED, Sweeney WE Jr, Park F. 2011Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents. FASEB J. 25:1844-55.
Rowe RG, Keena D, Sabeh F, Willis AL, Weiss SJ. 2011Pulmonary fibroblasts mobilize the membrane-tethered matrix metalloprotease, MT1-MMP, to destructively remodel and invade interstitial type I collagen barriers. Am J Physiol Lung Cell Mol Physiol. 301:L683-L692.
Rowe RG, Lin Y, Shimizu-Hirota R, Hanada S, Neilson EG, Greenson JK, Weiss SJ. 2011Hepatocyte-derived Snail1 propagates liver fibrosis progression. Mol Cell Biol. 31:2392-2403.
Saqui-Salces M, Keeley TM, Grosse AS, Qiao XT, El-Zaatari M, Gumucio DL, Samuelson LC, Merchant JL.2011Gastric tuft cells express DCLK1 and are expanded in hyperplasia. Histochem Cell Biol. 136:191-204.
Scheys JO, Heaton JH, Hammer GD. 2011Evidence of adrenal failure in aging Dax1-deficient mice. Endocrinology. 152:3430-3439.
Schwab KR, Patel SR, Dressler GR.2011Role of PTIP in class switch recombination and long-range chromatin interactions at the immunoglobulin heavy chain locus. Mol Cell Biol. 31:1503-1511.
Sheng L, Cho KW, Zhou Y, Shen H, Rui L.2011Lipocalin 13 protein protects against hepatic steatosis by both inhibiting lipogenesis and stimulating fatty acid β-oxidation. J Biol Chem. 286:38128-38135.
Singer BH, Gamelli AE, Fuller CL, Temme SJ, Parent JM, Murphy GG. 2011Compensatory network changes in the dentate gyrus restore long-term potentiation following ablation of neurogenesis in young-adult mice. Proc Natl Acad Sci U S A. 108:5437-5442.
Stein AB, Jones TA, Herron TJ, Patel SR, Day SM, Noujaim SF, Milstein ML, Klos M, Furspan PB, Jalife J, Dressler GR.2011Loss of H3K4 methylation destabilizes gene expression patterns and physiological functions in adult murine cardiomyocytes. J Clin Invest. 2641-2650.
Strickland FM, Hewagama A, Lu Q, Wu A, Hinderer R, Webb R, Johnson K, Sawalha AH, Delaney C, Yung R, Richardson BC.2011Environmental exposure, estrogen and two X chromosomes are required for disease development in an epigenetic model of lupus. J Autoimmun. J Autoimmun. 38):J135-143.
Tan M, Li Y, Yang R, Xi N, Sun Y.2011Inactivation of SAG E3 ubiquitin ligase blocks embryonic stem cell differentiation and sensitizes leukemia cells to retinoid acid. PLoS One. 6:e27726.
Tan M, Zhao Y, Kim S-J, Liu M, Jia L, Saunders TL, Zhu U, Sun Y. 2011SAG/RBX2/ROC2 E3 Ubiquitin Ligase Is Essential for Vascular and Neural Development by Targeting NF1 for Degradation. Dev Cell. 21:1062-1076.
Taylor M, Qu A, Anderson ER, Matsubara T, Martin A, Gonzalez FJ, Shah YM. 2011Hypoxia-inducible factor-2? mediates the adaptive increase of intestinal ferroportin during iron deficiency in mice. Gastroenterology. 140:2044-2055.
Terahara K, Nochi T, Yoshida M, Takahashi Y, Goto Y, Hatai H, Kurokawa S, Jang MH, Kweon MN, Domino SE, Hiroi T, Yuki Y, Tsunetsugu-Yokota Y, Kobayashi K, Kiyono H. 2011Distinct fucosylation of M cells and epithelial cells by Fut1 and Fut2, respectively, in response to intestinal environmental stress. Biochem Biophys Res Commun. 404:822-828. 
Waterson RE, Thompson CG, Mabe NW, Kaur K, Talbot JN, Neubig RR, Rorabaugh BR. 2011G{alpha}i2-mediated protection from ischaemic injury is modulated by endogenous RGS proteins in the mouse heart. Cardiovasc Res. 91: 45-52.
Wei J, Melichian D, Komura K, Hinchcliff M, Lam AP, Lafyatis R, Gottardi CJ, MacDougald OA, Varga J.2011Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma? Arthritis Rheum. 63:1707-1717.
Witten IB, Steinberg EE, Lee SY, Davidson TJ, Zalocusky KA, Brodsky M, Yizhar O, Cho SL, Gong S, Ramakrishnan C, Stuber GD, Tye KM, Janak PH, Deisseroth K. 2011Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement. Neuron. 72:721-733.
Wu J, Chen Y, Lu LY, Wu Y, Paulsen MT, Ljungman M, Ferguson DO, Yu X. 2011Chfr and RNF8 synergistically regulate ATM activation. Nat Struct Mol Biol. 18:761-768.
Yasuda M, Johnson-Venkatesh EM, Zhang H, Parent JM, Sutton MA, Umemori H. 2011Multiple forms of activity-dependent competition refine hippocampal circuits in vivo. Neuron. 70:1128-1142.
Yu T, Shakkottai VG, Chung C, Lieberman AP.2011Temporal and cell-specific deletion establishes that neuronal Npc1 deficiency is sufficient to mediate neurodegeneration.. Hum Mol Genet. 20: 4440-4451.
Zacharias AL, Lewandoski M, Rudnicki MA, Gage PJ. 2011Pitx2 is an upstream activator of extraocular myogenesis and survival. Dev Biol. 349:395-405.
Zacharias WJ, Madison BB, Kretovich KE, Walton KD, Richards N, Udager AM, Li X, Gumucio DL. 2011Hedgehog signaling controls homeostasis of adult intestinal smooth muscle. Dev Biol. 355:152-162.
Zhang K, Wang S, Malhotra J, Hassler JR, Back SH, Wang G, Chang L, Xu W, Miao H, Leonardi R, Chen YE, Jackowski S, Kaufman RJ. 2011The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis.EMBO J. 30:1357-1375.
Zhang B, Zheng C, Zhu M, Tao J, Vasievich MP, Baines A, Kim J, Schekman R, Kaufman RJ, Ginsburg D.2011Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of {alpha}1-antitrypsin. Blood. 118: 3384-3391.
Zhdanova O, Srivastava S, Di L, Li Z, Tchelebi L, Dworkin S, Johnstone DB, Zavadil J, Chong MM, Littman DR, Holzman LB, Barisoni L, Skolnik EY. 2011The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy. Kidney Int. 80:719-730.
Zhu L, Chang C-H, Dunnick WA.2011Excessive amounts of mu heavy chain block B cell development. Int Immunol. 23: 545-551.
Abe A, Kelly R, Shayman JA. 2010The measurement of lysosomal phospholipase A2 activity in plasma. J Lipid Res. 51:2464-2470. 
Anand S, Majeti BK, Acevedo LM, Murphy EA, Mukthavaram R, Scheppke L, Huang M, Shields DJ, Lindquist JN, Lapinski PE, King PD, Weis SM, Cheresh DA.2010MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis. Nat Med. 16:909-14.
Bjork BC, Fujiwara Y, Davis SW, Qiu H, Saunders TL, Sandy P, Orkin S, Camper SA, Beier DR. 2010A Transient Transgenic RNAi Strategy for Rapid Characterization of Gene Function during Embryonic Development. PLoS One. 5:e14375.
Brackenbury WJ, Calhoun JD, Chen C, Miyazaki H, Nukina N, Oyama F, Ranscht B, Isom LL.2010Functional reciprocity between Na+ channel Nav1.6 and beta1 subunits in the coordinated regulation of excitability and neurite outgrowth. Proc Natl Acad Sci U S A. 107:2283-2288.
Carvalho LR, Brinkmeier ML, Castinetti F, Ellsworth BS, Camper SA.2010Corepressors TLE1 and TLE3 interact with HESX1 and PROP1. Mol Endocrinol. 24:754-65.
Chun YH, Lu Y, Hu Y, Krebsbach PH, Yamada Y, Hu JC, Simmer JP.2010Transgenic rescue of enamel phenotype in Ambn null mice. J Dent Res. 89:1414-1420. 
Daniel JA, Santos MA, Wang Z, Zang C, Schwab KR, Jankovic M, Filsuf D, Chen HT, Gazumyan A, Yamane A, Cho YW, Sun HW, Ge K, Peng W, Nussenzweig MC, Casellas R, Dressler GR, Zhao K, Nussenzweig A.2010PTIP promotes chromatin changes critical for immunoglobulin class switch recombination. Science. 329:917-923. 
Davis SW, Castinetti F, Carvalho LR, Ellsworth BS, Potok MA, Lyons RH, Brinkmeier ML, Raetzman LT, Carninci P, Mortense AH, Hayashizaki Y, Arnhold IJ, Mendonça BB, Brue T, Camper SA.2010Molecular mechanisms of pituitary organogenesis: In search of novel regulatory genes. Mol Cell Endocrinol. 323:4-19.
Depianto D, Kerns ML, Dlugosz AA, Coulombe PA.2010Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin. Nat Genet. 42:910-914.
Elrick MJ, Pacheco CD, Yu T, Dadgar N, Shakkottai VG, Ware C, Paulson HL, Lieberman AP.2010Conditional Niemann-Pick C mice demonstrate cell autonomous Purkinje cell neurodegeneration. Hum Mol Genet.19:837-847.
El-Zaatari M, Zavros Y, Tessier A, Waghray M, Lentz S, Gumucio D, Todisco A, Merchant JL. 2010Intracellular calcium-release and protein kinase C-activation stimulate sonic hedgehog gene expression during gastric acid secretion. Gastroenterology. 139:2061-2071.
Hebda-Bauer EK, Pletsch A, Darwish H, Fentress H, Simmons TA, Wei Q, Watson SJ, Akil H. 2010Forebrain glucocorticoid receptor overexpression increases environmental reactivity and produces a stress-induced spatial discrimination deficit. Neuroscience. 169:645-653.
Hodish I, Liu M, Rajpal G, Larkin D, Holz RW, Adams A, Liu L, Arvan P.2010Misfolded proinsulin affects bystander proinsulin in neonatal diabetes. J Biol Chem. 285:685-94.
Hurd EA, Poucher HK, Cheng K, Raphael Y, Martin DM.2010The ATP-dependent chromatin remodeling enzyme CHD7 regulates pro-neural gene expression and neurogenesis in the inner ear. Development. 137:3139-3150.
Kaufman RJ, Back SH, Song B, Han J, Hassler J. 2010The unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in β-cells. Diabetes Obes Metab. 12 Suppl 2:99-107.
Kitajiri SI, Sakamoto T, Belyantseva IA, Goodyear RJ, Stepanyan R, Fujiwara I, Bird JE, Riazuddin S, Riazuddin S, Ahmed ZM, Hinshaw JE, Sellers J, Bartles JR, Hammer JA 3rd, Richardson GP, Griffith AJ, Frolenkov GI, Friedman TB.2010Actin-Bundling Protein TRIOBP Forms Resilient Rootlets of Hair Cell Stereocilia Essential for Hearing. Cell. 141:786 – 798.
Krebs CJ, Robins DM. 2010A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction. Biol Reprod. 82:662-668.
Lefevre GM, Patel SR, Kim D, Tessarollo L, Dressler GR. 2010Altering a histone H3K4 methylation pathway in glomerular podocytes promotes a chronic disease phenotype. PLoS Genet. 6:e1001142.
Leshan RL, Opland DM, Louis GW, Leinninger GM, Patterson CM, Rhodes CJ, Münzberg H, Myers MG Jr.2010Ventral tegmental area leptin receptor neurons specifically project to and regulate cocaine- and amphetamine-regulated transcript neurons of the extended central amygdala. J Neurosci. 30:5713-23.
Li JY, Chai BX, Zhang W, Wang H, Mulholland MW.2010Expression of ankyrin repeat and suppressor of cytokine signaling box protein 4 (Asb-4) in proopiomelanocortin neurons of the arcuate nucleus of mice produces a hyperphagic, lean phenotype.Endocrinology.151:134-142
Li X, Corsa CA, Pan PW, Wu L, Ferguson D, Yu X, Min J, Dou Y. 2010MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1. Mol Cell Biol. 30:5335-5347. 
Lo CM, King A, Samuelson LC, Kindel TL, Rider T, Jandacek RJ, Raybould HE, Woods SC, Tso P.2010Cholecystokinin knockout mice are resistant to high-fat diet-induced obesity. Gastroenterology. 138:1997-2005. 
Louis GW, Leinninger GM, Rhodes CJ, Myers MG Jr. 2010Direct innervation and modulation of orexin neurons by lateral hypothalamic LepRb neurons. J Neurosci. 30:11278-11287.
Lu LY, Wu J, Ye L, Gavrilina G, Saunders TL, Yu X.2010RNF8-Dependent Histone Modifications Regulate Nucleosome Removal during Spermatogenesis, Dev. Cell. 18:371-384.
Ma H, Togawa A, Soda K, Zhang J, Lee S, Ma M, Yu Z, Ardito T, Czyzyk J, Diggs L, Joly D, Hatakeyama S, Kawahara E, Holzman L, Guan JL, Ishibe S. 2010Inhibition of Podocyte FAK Protects against Proteinuria and Foot Process Effacement. J Am Soc Nephrol. 21:1145-1156.
Martin MS, Dutt K, Papale LA, Dubé CM, Dutton SB, de Haan G, Shankar A, Tufik S, Meisler MH, Baram TZ, Goldin AL, Escayg A.2010Altered function of the SCN1A voltage-gated sodium channel leads to gamma-aminobutyric acid-ergic (GABAergic) interneuron abnormalities. J Biol Chem. 285:9823-9834.
Mo K, Razak Z, Rao P, Yu Z, Adachi H, Katsuno M, Sobue G, Lieberman AP, Westwood JT, Monks DA.2010Microarray analysis of gene expression by skeletal muscle of three mouse models of Kennedy disease/spinal bulbar muscular atrophy. PLoS One. 5:e12922.
Morris DL, Cho KW, Rui L.2010Critical Role of the Src Homology 2 (SH2) Domain of Neuronal SH2B1 in the Regulation of Body Weight and Glucose Homeostasis in Mice. Endocrinology. 151:3643-3451.
Murai K, Qiu R, Zhang H, Wang J, Wu C, Neubig RR, Lu Q. 2010Gα subunit coordinates with ephrin-B to balance self-renewal and differentiation in neural progenitor cells.Stem Cells. 28:1581-1589.
Nakada D, Saunders TL, Morrison SJ. 2010Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature. 468:653-658.
Nishino J, Saunders TL, Sagane K, Morrison SJ. 2010Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. J Neurosci. 30:15228-15240.
Osorio N, Cathala L, Meisler MH, Crest M, Magistretti J, Delmas P. 2010Persistent Nav1.6 current at axon initial segments tunes spike timing of cerebellar granule cells. J Physiol. 588:651-670.
Pierce A, Wei R, Halade D, Yoo SE, Ran Q, Richardson A. 2010A Novel mouse model of enhanced proteostasis: Full-length human heat shock factor 1 transgenic mice. Biochem Biophys Res Commun. 402:59-65.
Robertson S, Ishida-Takahashi R, Tawara I, Hu J, Patterson CM, Jones JC, Kulkarni RN, Myers MG Jr. 2010Insufficiency of Janus kinase 2-autonomous leptin receptor signals for most physiologic leptin actions. Diabetes. 59:782-90. 
Saqui-Salces M, Merchant JL. 2010Hedgehog signaling and gastrointestinal cancer. Biochim Biophys Acta. 1803:786-795.
Saunders TL.2010A survey of internet resources for mouse development. Methods Enzymol. 476:3-21.
Saunders TL, Sobieszczuk P. 20109th transgenic technology meeting (TT2010) in Berlin, Germany: a meeting report. Transgenic Res. 19:1145-1148.
Shinohara M, Mao M, Keeley TM, El-Zaatari M, Lee HJ, Eaton KA, Samuelson LC, Merchant JL, Goldenring JR, Todisco A.2010Bone Morphogenetic Protein signaling Regulates Gastric Epithelial Cell Development and Proliferation in Mice. Gastroenterology. 139:2050-2060.
Signarvic RS, Cierniewska A, Stalker TJ, Fong KP, Chatterjee MS, Hess PR, Ma P, Diamond SL, Neubig RR, Brass LF. 2010RGS/Gi2alpha interactions modulate platelet accumulation and thrombus formation at sites of vascular injury. Blood. 116:6092-6100. 
Sisson TH, Mendez M, Choi K, Subbotina N, Courey A, Cunningham A, Dave A, Engelhardt JF, Liu X, White ES, Thannickal VJ, Moore BB, Christensen PJ, Simon RH. 2010Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis. Am J Respir Crit Care Med. 181:254-263.
Smalley-Freed WG, Efimov A, Burnett PE, Short SP, Davis MA, Gumucio DL, Washington MK, Coffey RJ, Reynolds AB. 2010p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice. J Clin Invest. 120:1824-1835.
Smith DE, Hu Y, Shen H, Nagaraja TN, Fenstermacher JD, Keep RF. 2010Distribution of glycylsarcosine and cefadroxil among cerebrospinal fluid, choroid plexus, and brain parenchyma after intracerebroventricular injection is markedly different between wild-type and Pept2 null mice. J Cereb Blood Flow Metab. 31:250-261.
Song W, Ren D, Li W, Jiang L, Cho KW, Huang P, Fan C, Song Y, Liu Y, Rui L.2010SH2B regulation of growth, metabolism, and longevity in both insects and mammals. Cell Metab. 11:427-437.
Steenhard BM, Isom K, Stroganova L, St John PL, Zelenchuk A, Freeburg PB, Holzman LB, Abrahamson DR.2010Deletion of von Hippel-Lindau in glomerular podocytes results in glomerular basement membrane thickening, ectopic subepithelial deposition of collagen {alpha}1{alpha}2{alpha}1(IV), expression of neuroglobin, and proteinuria. Am J Pathol.177:84-96. 
Swaroop A, Kim D, Forrest D.2010Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina. Nat Rev Neurosci. 11:563-576.
Talbot JN, Jutkiewicz EM, Graves SM, Clemans CF, Nicol MR, Mortensen RM, Huang X, Neubig RR, Traynor JR. 2010RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects. Proc Natl Acad Sci U S A107:11086-91.
Tan M, Zhu Y, Kovacev J, Zhao Y, Pan ZQ, Spitz DR, Sun Y. 2010Disruption of Sag/Rbx2/Roc2 induces radiosensitization by increasing ROS levels and blocking NF-kappaB activation in mouse embryonic stem cells. Free Radic Biol Med. 49:976-983. 
Uebachs M, Opitz T, Royeck M, Dickhof G, Horstmann MT, Isom LL, Beck H.2010Efficacy loss of the anticonvulsant carbamazepine in mice lacking sodium channel beta subunits via paradoxical effects on persistent sodium currents. J Neurosci. 30:8489-501.
VanDussen KL, Samuelson LC.2010 Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate.Dev Biol. 346:215-223. 
Wang HH, Portincasa P, Liu M, Tso P, Samuelson LC, Wang DQ.2010Effect of gallbladder hypomotility on cholesterol crystallization and growth in CCK-deficient mice. Biochim Biophys Acta. 1801:138-146.
Wang Y, Heilig KO, Saunders T, Minto AW, Deb DK, Chang A, Brosius FC 3rd, Monteiro C, Heilig CW.2010Transgenic Overexpression of GLUT1 in Mouse Glomeruli Produces Renal Disease Resembling Diabetic Glomerulosclerosis. Am J Physiol Renal Physiol. 299:F99-F111.
Westrick RJ, Mohlke KL, Korepta LM, Yang AY, Zhu G, Manning SL, Winn ME, Dougherty KM, Ginsburg D. 2010Spontaneous Irs1 passenger mutation linked to a gene-targeted SerpinB2 allele. Proc Natl Acad Sci U S A. 107:16904-16909.
Xiang J, Jiang H, Hu Y, Smith DE, Keep RF. 2010Kyotorphin transport and metabolism in rat and mouse neonatal astrocytes. Brain Res. 1347:11-8. 
Zacharias WJ, Li X, Madison BB, Kretovich K, Kao JY, Merchant JL, Gumucio DL.2010Hedgehog Is an Anti-Inflammatory  Epithelial Signal for the Intestinal Lamina Propria. Gastroenterology. 138:2368-77.
Zhang H, Schin M, Saha J, Burke K, Holzman LB, Filipiak WE, Saunders T, Heilig CW, Brosius FC 3rd.2010Podocyte Specific Overexpression of GLUT1 Surprisingly Reduces Mesangial Matrix Expansion in Diabetic Nephropathy in Mice. Am J Physiol Renal Physiol.  299:F91-98.
Zhao X, Peng X, Sun S, Park AY, Guan JL.2010Role of kinase-independent and -dependent functions of FAK in endothelial cell survival and barrier function during embryonic development. J Cell Biol. 189:955-965.
Aman TK, Grieco-Calub TM, Chen C, Rusconi R, Slat EA, Isom LL, Raman IM.2009Regulation of persistent Na current by interactions between beta subunits of voltage-gated Na channels. J Neurosci. 29:2027-2042.
Back SH, Scheuner D, Han J, Song B, Ribick M, Wang J, Gildersleeve RD, Pennathur S, Kaufman RJ.2009Translation attenuation through eIF2alpha phosphorylation prevents oxidateive stress and maintains the differentiated state in beta cells. Cell Metab. 10:13-26.
Belyantseva IA, Perrin BJ, Sonnemann KJ, Zhu M, Stepanyan R, McGee J, Frolenkov GI, Walsh EJ, Friderici KH, Friedman TB, Ervasti JM.2009Gamma-actin is required for cytoskeletal maintenance but not development. Proc Natl Acad Sci U S A. 106:9703-9708.
Chang J, Wang Z, Tan, E, Fan Z, McCauley L, Franceschi R, Guan K, Krebsbach PH, Wang CY. 2009Inhibition of osteoblastic bone formation by nuclear factor-kappaB. Nat. Med. 15: 682-68.
Chrispell JD, Feathers KL, Kane MA, Kim CY, Brooks M, Khanna R, Kurth I, Hübner CA, Gal A, Mears AJ, Swaroop A,Napoli JL, Sparrow JR, Thompson DA.2009Rdh12 activity and effects on retinoid processing in the murine retina. J Biol Chem. 284:21468-77.
Coonce MM, Rabideau AC, McGee S, Smith K, Narayan P.2009Impact of a constitutively active luteinizing hormone receptor on testicular gene expression and postnatal Leydig cell development.Mol Cell Endocrinol. 298:33-41.
Dai C, Stolz DB, Kiss LP, Monga SP, Holzman LB, Liu Y. 2009Wnt/beta-catenin signaling promotes podocyte dysfunction and albuminuria. J Am Soc Nephrol. 20:1997-2008
Deng Y, Guo X, Ferguson DO, Chang S. 2009Multiple roles for MRE11 at uncapped telomeres. Nature. 460:914-98.
Diallo-Krou E, Yu J, Colby LA, Inoki K, Wilkinson J, Thomas DG, Giordano TJ, Koenig RJ.2009Paired box gene 8-peroxisome proliferator-activated receptor-gamma fusion protein and loss of phosphatase and tensin homolog synergistically cause thyroid hyperplasia in transgenic mice. Endocrinology. 150:5181-90.
Domino, S. E., Hurd, E. A., Thomsson, K. A., Karnak, D. M., Holmen Larsson, J. M., Thomsson, E., Backstrom, M., Hansson, G. C. 2009Cervical mucins carry alpha(1,2)fucosylated glycans that partly protect from experimental vaginal candidiasis. Glycoconj. J. 26:1125-1134.
Dunnick WA, Collins JT, Shi J, Westfield G, Fontaine C, Hakimpour P, Papavasiliou FN. 2009Switch recombination and somatic hypermutation are controlled by the heavy chain 3′ enhancer region. J Exp Med. 206:2613-2623.
Fahim, A. T., Wang, H., Feng, J., and Ginsburg, D. 2009Transgenic overexpression of a stable Plasminogen Activator Inhibitor-1 variant. Thromb. Res. 123: 785-792.
Franceschi, R. T., Ge, C., Xiao, G., Roca, H., and Jiang, D. 2009Transcriptional regulation of osteoblasts. Cells Tissues Organs 189: 144-152. 
Goldenstein BL, Nelson BW, Xu K, Luger EJ, Pribula JA, Wald JM, O’Shea LA, Weinshenker D, Charbeneau RA, Huang X, Neubig RR, Doze VA2009Regulator of G protein signaling protein suppression of Galphao protein-mediated alpha2A adrenergic receptor inhibition of mouse hippocampal CA3 epileptiform activity.Mol Pharmacol. 75:1222-1230.
Girirajan S, Elsea SH. 2009Abnormal maternal behavior, altered sociability, and impaired serotonin metabolism in Rai1-transgeni c mice. Mamm Genome. 20:247-255.
Harding HP, Zhang Y, Scheuner D, Chen JJ, Kaufman RJ, Ron D.2009Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development. Proc Natl Acad Sci U S A. 106:1832-7.
He S, Iwashita T, Buchstaller J, Molofsky AV, Thomas D, Morrison SJ.2009Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo. Dev Biol. 328:257-272.
Hosoya T, Kuroha T, Moriguchi T, Cummings D, Maillard I, Lim KC, Engel JD. 2009GATA-3 is required for early T lineage progenitor development. J Exp Med. 206:2987-3000.
Huang X, Fu Y, Charbeneau RA, Neubig RR. 2009GNAI2 and regulators of G protein signaling as a potential Noonan syndrome mechanism. Med Hypotheses. 73:56-59. 
Icaza EE, Huang X, Fu Y, Neubig RR, Baghdoyan HA, Lydic R. 2009Icaza EE, Huang X, Fu Y, Neubig RR, Baghdoyan HA, Lydic R. 2009. Isoflurane-induced changes in righting response and breathing are modulated by RGS proteins.Anesth Analg. 109:1500-1500.
Jia L, Oh EC, Ng L, Srinivas M, Brooks M, Swaroop A, Forrest D. 2009Retinoid-related orphan nuclear receptor ROR{beta} is an early-acting factor in rod photoreceptor development. Proc Natl Acad Sci U S A. 1061:7534-7539.
Jia L, Sun Y. 2009Jia L, Sun Y. 2009. RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival. Cell Div. 4:16
Jiang H, Hu Y, Keep RF, Smith DE. 2009Enhanced antinociceptive response to intracerebroventricular kyotorphin in Pept2 null mice. J Neurochem. 109:1536-43.
Kamal MA, Jiang H, Hu Y, Keep RF, Smith D. 2009Influence of genetic knockout of Pept2 on the in vivo disposition of endogenous and exogenous carnosine in wild-type and Pept2 null mice.Am J Physiol Regul Integr Comp Physiol. 296:R986-91.
Kim D, Patel SR, Xiao H, Dressler GR. 2009The role of PTIP in maintaining embryonic stem cell pluripotency. Stem Cells.27:1516-1523.
Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL. 2009Paracrine Hedgehog Signaling in Stomach and Intestine: New Roles for Hedgehog in Gastrointestinal Patterning. Gastroenterology 137:618-628. 
Krebs, C. J., Khan, S., MacDonald, J. W., Sorenson, M., and Robins, D. M. 2009Regulator of sex-limitation KRAB zinc finger proteins modulate sex-dependent and -independent liver metabolism. Physiol. Genomics 38: 16-28. 
Kurachi, S., Huo, J. S., Ameri, A., Zhang, K., Yoshizawa, A. C., and Kurachi, K. 2009An age-related homeostasis mechanism is essential for spontaneous amelioration of hemophilia B Leyden. Proc. Natl. Acad. Sci. U. S. A. 106: 7921-7926. 
Lapinski PE, Oliver JA, Bodie JN, Marti F, King PD. 2009The T-cell-specific adapter protein family: TSAd, ALX, and SH2D4A/SH2D4B. Immunol Rev. 232:240-54.
Layman, W. S., McEwen, D. P., Beyer, L. A., Lalani, S. R., Fernbach, S. D., Oh, E., Swaroop, A., Hegg, C. C., Raphael, Y., Martens, J. R., et al. 2009Defects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndrome. Hum. Mol. Genet. 18: 1909-1923. 
Leshan RL, Louis GW, Jo YH, Rhodes CJ, Münzberg H, Myers MG Jr.2009Direct innervation of GnRH neurons by metabolic- and sexual odorant-sensing leptin receptor neurons in the hypothalamic ventral premammillary nucleus. J Neurosci. 29:3138-3147.
Li X, Gonzalez ME, Toy K, Filzen T, Merajver SD, Kleer CG.2009Targeted overexpression of EZH2 in the mammary gland disrupts ductal morphogenesis and causes epithelial hyperplasia. Am J Pathol. 175:1246-1254.
Li X, Udager AM, Hu C, Qiao XT, Richards N, Gumucio DL.2009Dynamic patterning at the pylorus: formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn. 238:3205-3217.
Li Y, Gudjonsson, J E, Woods TL, Zhang T, Johnston A, Stoll, SW, Elder JT. 2009Transgenic expression of S100A2 in hairless mouse skin enhances Cxcl13 mRNA in response to solar-simulated radiation. Arch. Dermatol. Res. 301: 205-217.
Liang H, Balas B, Tantiwong P, Dube J, Goodpaster BH, O’Doherty RM, DeFronzo RA, Richardson A, Musi N, Ward WF. 2009Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity. Am J Physiol Endocrinol Metab. 296: E945-E954. 
Liang H, Yoo SE, Na R, Walter CA, Richardson A, Ran Q. 2009Short form glutathione peroxidase 4 is the essential isoform required for survival and somatic mitochondrial functions. J Biol Chem. 284: 30836-30844.
Liu T, Hu B, Choi YY, Chung M, Ullenbruch M, Yu H, Lowe JB, Phan SH. 2009Notch1 signaling in FIZZ1 induction of myofibroblast differentiation. Am J Pathol. 174: 1745-1755.
Morris DL, Cho KW, Zhou Y, Rui L. 2009SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins. Diabetes. 58:2039-2047.
Murrey, H. E., Ficarro, S. B., Krishnamurthy, C., Domino, S. E., Peters, E. C., and Hsieh-Wilson, L. C. 2009Identification of the Plasticity-Relevant Fucose-(1-2)-Galactose Proteome from Mouse Olfactory Bulb. Biochemistry. 48:7261-7270.
Nasonkin IO, Potok MA, Camper SA. 2009Cre-mediated recombination in pituitary somatotropes. Genesis. 47: 55-60. 
Nelson, L. T., Rakshit, S., Sun, H., and Wellik, D. M. 2009Generation and expression of a Hoxa11eGFP targeted allele in mice. Dev. Dyn. 237: 3410-3416.
O’Malley HA, Shreiner AB, Chen GH, Huffnagle GB, Isom LL. 2009Loss of Na+ channel beta2 subunits is neuroprotective in a mouse model of multiple sclerosis. Mol Cell Neurosci. 40:143-155. 
Papagerakis P, Hu Y, Ye L, Feng JQ, Simmer JP, Hu JC. 2009Identifying promoter elements necessary for enamelin tissue-specific expression. Cells Tissues Organs. 189:98-104. 
Ragland, R. L., Arlt, M. F., Hughes, E. D., Saunders, T. L., and Glover, T. W.2009Mice hypomorphic for Atr have increased DNA damage and abnormal checkpoint response. Mamm. Genome 20:375-385 .
Rosenzweig DH, Nair KS, Levay K, Peshenko IV, Crabb JW, Dizhoor AM, Slepak VZ.2009Interaction of retinal guanylate cyclase with the alpha subunit of transducin: potential role in transducin localization. Biochem J. 417:803-812.
Rowe RG, Li XY, Hu Y, Saunders TL, Virtanen I, Garcia de Herreros A, Becker KF, Ingvarsen S, Engelholm LH, Bommer GT, Fearon ER, Weiss SJ. 2009Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs. J Cell Biol.184:399-408.
Sato Y, Wharram BL, Lee SK, Wickman L, Goyal M, Venkatareddy M, Chang JW, Wiggins JE, Lienczewski C, Kretzler M, Wiggins RC. 2009Urine podocyte mRNAs mark progression of renal disease. J Am Soc Nephrol. 20:1041-52. 
Sabeh, F., Li, X. Y., Saunders, T. L., Rowe, R. G., and Weiss, S. J. 2009Secreted versus membrane-anchored collagenases: Relative roles in fibroblast-dependent collagenolysis and invasion. J. Biol. Chem. 284:23001-11.
Singer BH, Jutkiewicz EM, Fuller CL, Lichtenwalner RJ, Zhang H, Velander A J, Li X, Gnegy ME, Burant CF, Parent JM.2009Conditional ablation and recovery of forebrain neurogenesis in the mouse. J. Comp. Neurol. 514: 567-582.
Sun H. Wang X, Degen JL, Ginsburg D.2009Reduced thrombin generation increases host susceptibility to group A streptococcal infection.Blood. 113:1358-64.
Tan M, Davis SW, Saunders TL, Zhu Y, Sun Y.2009RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27. Proc Natl Acad Sci U S A. 106:6203-6208.
Van Keuren ML, Gavrilina GB, Filipiak WE, Zeidler MG, Saunders TL. 2009Generating transgenic mice from bacterial artificial chromosomes: transgenesis efficiency, integration and expression outcomes. Transgenic Res. 18:769-85.
Vesely ED, Heilig CW, Brosius FC 3rd. 2009GLUT1-induced cFLIP expression promotes proliferation and prevents apoptosis in vascular smooth muscle cells. Am J Physiol Cell Physiol. 297:C759-765.
Wada M, Saunders TL, Morrow J, Milne GL, Walker KP, Dey SK, Brock TG, Opp MR, Aronoff DM, Smith WL. 2009Two pathways for cyclooxygenase-2 protein degradation in vivo.J Biol Chem. 284:30742-30753.
Wang HH, Portincasa P, Liu M, Tso P, Samuelson LC, Wang DQ. 2009Effect of gallbladder hypomotility on cholesterol crystallization and growth in CCK-deficient mice. Biochim Biophys Acta. 1801:138-146.
Wong SY, Seol AD, So PL, Ermilov AN, Bichakjian CK, Epstein EH Jr, Dlugosz AA, Reiter JF. 2009Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat Med. 15:1055-1061.
Yu Z, Wang AM, Robins DM, Lieberman AP.2009Altered RNA splicing contributes to skeletal muscle pathology in Kennedy disease knock-in mice. Dis Model Mech. 2:500-507.
Zhou H, Huang C, Yang M, Landel CP, Xia PY, Liu, YJ, Xia, XG. 2009Developing tTA transgenic rats for inducible and reversible gene expression. Int. J. Biol. Sci. 5: 171-181.
Akyol A, Hinoi T, Feng Y, Bommer GT, Glaser TM, Fearon ER. 2008Generating somatic mosaicism with a Cre recombinase-microsatellite sequence transgene. Nat Methods. 5:231-233.
Albertelli MA, O’Mahony OA, Brogley M, Tosoian J, Steinkamp M, Daignault S, Wojno K, Robins DM.2008Glutamine tract length of human androgen receptors affects hormone-dependent and -independent prostate cancer in mice. Hum Mol Genet.17:98-110.
Bauler TJ, Hendriks WJ, King PD.2008 The FERM and PDZ domain-containing protein tyrosine phosphatases, PTPN4 and PTPN3, are both dispensable for T cell receptor signal transduction. PLoS ONE. 3(12):e4014. 
Blumer JB, Lord K, Saunders TL, Pacchioni A, Black C, Lazartigues E, Varner KJ, Gettys TW, Lanier SM.2008Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function.Endocrinology. 149:3842-3849.
Blauwkamp MN, Yu J, Schin MA, Burke KA, Berry MJ, Carlson BA, Brosius FC 3rd, Koenig RJ. 2008Podocyte specific knock out of selenoproteins does not enhance nephropathy in streptozotocin diabetic C57BL/6 mice. BMC Nephrol. 9:7.
Brackenbury WJ, Davis TH, Chen C, Slat EA, Detrow MJ, Dickendesher TL, Ranscht B, Isom LL.2008Voltage-gated Na+ channel beta1 subunit-mediated neurite outgrowth requires Fyn kinase and contributes to postnatal CNS development in vivo. J Neurosci. 28:3246-3256.
Buis J, Wu Y, Deng Y, Leddon J, Westfield G, Eckersdorff M, Sekiguchi JM, Chang S, Feruson DO. 2008Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation. Cell. 135:85-96.
Charles MA, Mortensen AH, Potok MA, Camper SA.2008Pitx2 deletion in pituitary gonadotropes is compatible with gonadal development, puberty, and fertility. Genesis. 46:507-514.
Chauhan AK, Walsh MT, Zhu G, Ginsburg D, Wagner DD, Motto DG. 2008The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis.  Blood. 111:3452-7.
Chen L, Na R, Gu M, Salmon AB, Liu Y, Liang H, Qi W, Van Remmen H, Richardson A, Ran Q. 2008Reduction of mitochondrial H2O2 by overexpressing peroxiredoxin 3 improves glucose tolerance in mice. Aging Cell. 7:866-878.
Chen S, Wassenhove-McCarthy DJ, Yamaguchi Y, Holzman LB, van Kuppevelt TH, Jenniskens GJ, Wijnhoven TJ, Woods AC, McCarthy KJ. 2008Loss of heparan sulfate glycosaminoglycan assembly in podocytes does not lead to proteinuria. Kidney Int. 74:28-99. 
Corpening JC, Cantrell VA, Deal KK, Southard-Smith EM. 2008A Histone2BCerulean BAC transgene identifies differential expression of Phox2b in migrating enteric neural crest derivatives and enteric glia.Dev Dyn. 237:1119-1132. 
Day SM, Coutu P, Wang W, Herron TJ, Turner I, Shillingford M, Lacross NC, Converso KL, Piao L, Li J, Lopatin AN, Metzger JM.2008Cardiac-directed parvalbumin transgene expression in mice shows marked heart rate dependence of delayed Ca++ buffering action. Physiol Genomics. 33:312-322.
Elkouby-Naor, L., Abassi, Z., Lagziel, A., Gow, A., and Ben-Yosef, T. 2008Double gene deletion reveals lack of cooperation between claudin 11 and claudin 14 tight junction proteins. Cell Tissue Res. 333: 427-438.
Egashira N, Minematsu T, Miyai S, Takekoshi S, Camper SA, Osamura RY. 2008Pituitary Changes in Prop1 Transgenic Mice: Hormone Producing Tumors and Signet-ring Type Gonadotropes. Acta Histochem Cytochem.41:47-57.
Feathers KL, Lyubarsky AL, Khan NW, Teofilo K, Swaroop A, Williams DS, Pugh EN Jr, Thompson DA. 2008Nrl-Knockout Mice Deficient in Rpe65 Fail to Synthesize 11-cis Retinal and Cone Outer Segments. Invest Ophthalmol Vis Sci. 49: 1126-35.
Gage PJ, Qian M, Wu D, Rosenberg KI. 2008The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development. Dev Biol.317:310-324.
Gammie SC, Seasholtz AF, Stevenson SA. 2008Deletion of corticotropin-releasing factor binding protein selectively impairs maternal, but not intermale aggression. Neuroscience. 157:502-512.
Galli C, Zella LA, Fretz JA, Fu Q, Pike JW, Weinstein RS, Manolagas SC, O’Brien CA. 2008Targeted deletion of a distant transcriptional enhancer of the receptor activator of nuclear factor-kappaB ligand gene reduces bone remodeling and increases bone mass. Endocrinology. 149:146-53.
Girirajan S, Hauck PM, Williams S, Vlangos CN, Szomju BB, Solaymani-Kohal S, Mosier PD, White KL Jr, McCoy K, Elsea SH. 2008Tom1l2 hypomorphic mice exhibit increased incidence of infections and tumors and abnormal immunologic response. Mamm Genome. 19:246-262.
Girirajan, S., Patel, N., Slager, R. E., Tokarz, M. E., Bucan, M., Wiley, J. L., and Elsea, S. H. 2008How much is too much? Phenotypic consequences of Rai1 overexpression in mice. Eur. J. Hum. Genet. 16: 941-954.
Gammie SC, Seasholtz AF, Stevenson SA.2008Deletion of corticotropin-releasing factor binding protein selectively impairs maternal, but not intermale aggression. Neuroscience. 157:502-12.
He H, Gu Q, Zheng M, Normolle D, Sun Y. 2008SAG/ROC2/RBX2 E3 ligase promotes UVB-induced skin hyperplasia, but not skin tumors, by simultaneously targeting c-Jun/AP-1 and p27. Carcinogenesis. 29:858-865.
Howell VM, de Haan G, Bergren S, Jones JM, Culiat CT, Michaud EJ, Frankel WN, Meisler MH.2008A targeted deleterious allele of the splicing factor SCNM1 in the mouse. Genetics. 180:1419-1427.
Hu, Y., Papagerakis, P., Ye, L., Feng, J. Q., Simmer, J. P., and Hu, J. C. 2008Distal cis-regulatory elements are required for tissue-specific expression of enamelin (Enam). Eur. J. Oral Sci. 116: 113-123
Huang X, Charbeneau RA, Fu Y, Kaur K, Gerin I, MacDougald OA, Neubig RR.2008Resistance to diet-induced obesity and improved insulin sensitivity in mice with a regulator of G protein signaling-insensitive G184S Gnai2 allele. Diabetes. 57:77-85. 
Jain RN, Al-Menhali AA, Keeley TM, Ren J, El-Zaatari M, Chen X, Merchant JL, Ross TS, Chew CS, Samuelson LC.2008Hip1r is expressed in gastric parietal cells and is required for tubulovesicle formation and cell survival in mice. J Clin Invest. 118:2459-70.
Ji B, Song J, Tsou L, Bi Y, Gaiser S, Mortensen R, Logsdon C. 2008Robust acinar cell transgene expression of CreErT via BAC recombineering. Genesis. 46:390-395.
Jia Q, McDill BW, Sankarapandian B, Wu S, Liapis H, Holzman LB, Capecchi MR, Miner JH, Chen F. 2008Ablation of developing podocytes disrupts cellular interactions and nephrogenesis both inside and outside the glomerulus. Am J Physiol Renal Physiol. 295:F1790-F1798.
Johnsen JM, Levy GG, Westrick RJ, Tucker PK, Ginsburg D.2008The endothelial-specific regulatory mutation, Mvwf1, is a common mouse founder allele. Mamm Genome. 19:32-40.
Kang W, Saqui-Salces M, Zavros Y, Merchant JL. 2008Induction of follistatin precedes gastric transformation in gastrin deficient mice. Biochem Biophys Res Commun. 376:573-577.
Kim J, Lauderdale JD. 2008Overexpression of pairedless Pax6 in the retina disrupts corneal development and affects lens cell survival. Dev Biol. 313:434-454. 
Lapinski PE, Oliver JA, Kamen LA, Hughes ED, Saunders TL, King PD.2008Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells. J Immunol. 181:2019-2027.
Lehoczky JA, Innis JW. 2008BAC transgenic analysis reveals enhancers sufficient for Hoxa13 and neighborhood gene expression in mouse embryonic distal limbs and genital bud. Evol Dev.10:421-432.
Luebke-Wheeler J, Zhang K, Battle M, Si-Tayeb K, Garrison W, Chhinder S, Li J, Kaufman RJ, Duncan SA.2008Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H. Hepatology. 48:1242-1250.
Lieberman AP, Robins DM. 2008The androgen receptor’s CAG/glutamine tract in mouse models of neurological disease and cancer. J Alzheimers Dis. 14:247-55.
Lo CM, Samuelson LC, Chambers JB, King A, Heiman J, Jandacek RJ, Sakai RR, Benoit SC, Raybould HE, Woods SC, Tso P. 2008Characterization of mice lacking the gene for cholecystokinin. Am J Physiol Regul Integr Comp Physiol. 294:R803-10.
Lu LY, Wood JL, Ye L, Minter-Dykhouse K, Saunders TL, Yu X, Chen J. 2008Aurora A is essential for early embryonic development and tumor suppression. J Biol Chem. 283:31785-31790.
Lu LY, Wood JL, Minter-Dykhouse K, Ye L, Saunders TL, Yu X, Chen J. 2008Polo-like kinase 1 is essential for early embryonic development and tumor suppression. Mol Cell Biol.28:6870-6876.
Luebke-Wheeler J, Zhang K, Battle M, Si-Tayeb K, Garrison W, Chhinder S, Li J, Kaufman RJ, Duncan SA. 2008Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H. Hepatology. 48:1242-1250.
McKinney BC, Chow CY, Meisler MH, Murphy GG. 2008Exaggerated emotional behavior in mice heterozygous null for the sodium channel Scn8a (Nav1.6). Genes Brain Behav. 7:629-638.
Mensah-Osman E, Labut E, Zavros Y, El-Zaatari M, Law DJ, Merchant JL. 2008Regulated expression of the human gastrin gene in mice. Regul Pept. 151:115-122.
Michael LE, Westerman BA, Ermilov AN, Wang A, Ferris J, Liu J, Blom M, Ellison DW, van Lohuizen M, Dlugosz AA. 2008Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion. Neoplasia. 10:1343-1349.
Nelson LT, Rakshit S, Sun H, Wellik DM.2008Generation and expression of a Hoxa11eGFP targeted allele in mice. Dev Dyn. 237:3410-3416.
O’Mahony OA, Steinkamp MP, Albertelli MA, Brogley M, Rehman H, Robins DM. 2008Profiling human androgen receptor mutations reveals treatment effects in a mouse model of prostate cancer.  Mol Cancer Res. 6:1691-1701.
Oh EC, Cheng H, Hao H, Jia L, Khan NW, Swaroop A. 2008Rod differentiation factor NRL activates the expression of nuclear receptor NR2E3 to suppress the development of cone photoreceptors. Brain Res. 1236:16-29.
Palpant NJ, Day SM, Herron TJ, Converso KL, Metzger JM. 2008Single histidine substituted cardiac troponin I confers protection from age-related systolic and diastolic dysfunction. Cardiovasc Res. 80:209-218.
Pozzi A, Jarad G, Moeckel GW, Coffa S, Zhang X, Gewin L, Eremina V, Hudson BG, Borza DB, Harris RC, Holzman LB, Phillips CL, Fassler R, Quaggin SE, Miner JH, Zent R.2008Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity. Dev Biol. 316:288-301.
Robins DM, Albertelli MA, O’Mahony OA.2008Androgen receptor variants and prostate cancer in humanized AR mice. J Steroid Biochem Mol Biol. 108: 230-236.
Rousso DL, Gaber ZB, Wellik D, Morrisey EE, Novitch BG. 2008Coordinated actions of the forkhead protein Foxp1 and Hox proteins in the columnar organization of spinal motor neurons. Neuron.59:226-40. PubMed PMID: 18667151
Saul SM, Brzezinski JA 4th, Altschuler RA, Shore SE, Rudolph DD, Kabara LL, Halsey KE, Hufnagel RB, Zhou J, Dolan DF, Glaser T. 2008Math5 expression and function in the central auditory system. Mol Cell Neurosci. 37:153-169.
Sawalha AH, Jeffries M, Webb R, Lu Q, Gorelik G, Ray D, Osban J, Knowlton N, Johnson K, Richardson B.2008Defective T-cell ERK signaling induces interferon-regulated gene expression and overexpression of methylation-sensitive genes similar to lupus patients. Genes Immun. 9:368-378.
Shi S, Yu L, Chiu C, Sun Y, Chen J, Khitrov G, Merkenschlager M, Holzman LB, Zhang W, Mundel P, Bottinger EP.2008Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis. J Am Soc Nephrol. 19:2159-2169.
Skidmore JM, Cramer JD, Martin JF, Martin DM. 2008Cre fate mapping reveals lineage specific defects in neuronal migration with loss of Pitx2 function in the developing mouse hypothalamus and subthalamic nucleus. Mol Cell Neurosci. 37:696-707.
Tessari A, Pietrobon M, Notte A, Cifelli G, Gage PJ, Schneider MD, Lembo G, Campione M.2008Myocardial Pitx2 Differentially Regulates the Left Atrial Identity and Ventricular Asymmetric Remodeling Programs. Circ Res 102:813-822.
Tomlins SA, Laxman B, Varambally S, Cao X, Yu J, Helgeson BE, Cao Q, Prensner JR, Rubin MA, Shah RB, Mehra R, Chinnaiyan AM.2008Role of the TMPRSS2-ERG gene fusion in prostate cancer.  Neoplasia. 10:177-188.
Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA. 2008Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling. Nat Genet. 40:1130-5.
Yang H, Gumucio DL, Teitelbaum DH. 2008Intestinal specific overexpression of interleukin-7 attenuates the alternation of intestinal intraepithelial lymphocytes after total parenteral nutrition administration.  Ann Surg. 248:849-856. 
Yang H, Madison B, Gumucio DL, Teitelbaum DH.2008Specific overexpression of IL-7 in the intestinal mucosa: the role in intestinal intraepithelial lymphocyte development. Am J Physiol Gastrointest Liver Physiol.  294:G1421-30.
Zhang W, Chai B, Li JY, Wang H, Mulholland MW. 2008Effect of des-acyl ghrelin on adiposity and glucose metabolism. Endocrinology. 149:4710-4716.
Adams ME, Hurd EA, Beyer LA, Swiderski DL, Raphael Y, Martin DM.2007Defects in vestibular sensory epithelia and innervation in mice with loss of Chd7 function: implications for human CHARGE syndrome. J Comp Neurol.  504: 519-32.
Bauler TJ, Hughes ED, Arimura Y,Mustelin T,Saunders TL, King PD.2007Normal TCR signal transduction in mice that lack catalytically active PTPN3 protein tyrosine phosphatase.  J Immunol. 178:3680-3687.
Bennett CN, Ouyang H, Ma YL, Zeng Q, Gerin I, Sousa KM, Lane TF, Krishnan V, Hankenson KD, MacDougald OA. 2007Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation. J Bone Miner Res.22:1924-32.
Bommer GT, Gerin I, Feng Y, Kaczorowski AJ, Kuick R, Love RE, Zhai Y, Giordano TJ, Qin ZS, Moore BB, Macdougald OA, Cho KR, Fearon ER. 2007p53-Mediated Activation of miRNA34 Candidate Tumor-Suppressor Genes. Curr Biol.17:1298-307.
Bradley SV. Hyun TS. Oravecz-Wilson KI. Li L. Waldorff EI. Ermilov AN. Goldstein SA. Zhang CX. Drubin DG. Varela K. Parlow A. Dlugosz AA. Ross TS.2007Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1.  Human Molecular Genetics. 16:1279-92,
Chen C, Dickendesher DL, Oyama F, Miyazaki H, Nukina N, Isom LL. 2007Floxed allele for conditional inactivation of the voltage-gated sodium channel 1 subunit Scn1b. Genesis. 45:547-553. 
Costa-Mattioli M, Gobert D, Stern E, Gamache K, Colina R, Cuello C, Sossin W, Kaufman R, Pelletier J, Rosenblum K, Krnjević K, Lacaille JC, Nader K, Sonenberg N. 2007eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory. Cell.129:195-206. 
Davis SW, Camper SA. 2007Noggin regulates Bmp4 activity during pituitary induction.Dev Biol. 305:145-160.
Dentice M, Luongo C, Huang S, Ambrosio R, Elefante A, Mirebeau-Prunier D, Zavacki AM, Fenzi G, Grachtchouk M, Hutchin M, Dlugosz AA, Bianco AC, Missero C, Larsen PR, Salvatore D.2007Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes. Proc Natl Acad Sci U S A. 104:14466-14471.
Domino SE, Karnak DM, Hurd EA. 2007Cell surface fucosylation does not affect development of colon tumors in mice with germline Smad3 mutation. Tumour Biol. 28:77-83.
Drews VL, Shi K, de Haan G, Meisler MH. 2007Identification of evolutionarily conserved, functional noncoding elements in the promoter region of the sodium channel gene SCN8A. Mamm Genome. 18:723-731.
Elmore CL, Matthews RG.2007The many flavors of hyperhomocyst(e)inemia: insights from transgenic and inhibitor-based mouse models of disrupted one-carbon metabolism. Antioxid Redox Signal.9:1911-1921.
Elmore CL, Wu X, Leclerc D, Watson ED, Bottiglieri T, Krupenko NI, Krupenko SA, Cross JC, Rozen R, Gravel RA, Matthews RG.2007Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase. Mol Genet Metab. 91:85-97.
Fu Y, Huang X, Piao L, Lopatin AN, Neubig RR. 2007Endogenous RGS proteins modulate SA and AV nodal functions in isolated heart: implications for sick sinus syndrome and AV block. Am J Physiol Heart Circ Physiol. 292:H2532-9.
Ge C, Xiao G, Jiang D, Franceschi RT. 2007Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development. J Cell Biol. 176:709-718. 
Gong KQ, Yallowitz AR, Sun H, Dressler GR, Wellik DM.2007A Hox-Eya-Pax complex regulates early kidney developmental gene expression. Mol Cell Biol. 27:7661-668.
Gu Q, Bowden GT, Normolle D, Sun Y. 2007SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/NF-kappaB. J Cell Biol. 178:1009-1023.
Haremaki T, Fraser ST, Kuo YM, Baron MH, Weinstein DC. 2007Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation. Proc Natl Acad Sci U S A.104:12029-34.
Harvey SJ, Jarad G, Cunningham J, Rops AL, van der Vlag J, Berden JH, Moeller MJ, Holzman LB, Burgess RW, Miner JH. 2007Disruption of Glomerular Basement Membrane Charge through Podocyte-Specific Mutation of Agrin Does Not Alter Glomerular Permselectivity. Am J Pathol. 171:139–152.
Hinoi T, A, Theisen BK, Ferguson DO, Greenson JK, Williams BO, Cho KR, Fearon ER.2007Mouse model of colonic adenoma-carcinoma progression based on somatic apc inactivation. Cancer Res. 67: 9721-30.
Hu Y, Shen H, Keep RF, Smith DE. 2007Peptide transporter 2 (PEPT2) expression in brain protects against 5-aminolevulinic acid neurotoxicity. J Neurochem. 103:2058-2065. 
Huang X, Charbeneau RA, Fu Y, Kaur K, Gerin I, Macdougald OA, Neubig RR. 22007Resistance to diet-induced obesity and improved insulin sensitivity in mice with an RGS insensitive G184S Gnai2 allele. Diabetes. 57:77-85.
Hughes ED, Qu YY, Genik SJ, Lyons RH, Pacheco CD, Lieberman AP, Samuelson LC, Nasonkin IO, Camper SA, Van Keuren ML, Saunders TL. 2007Genetic variation in C57BL/6 ES cell lines and genetic instability in the Bruce4 C57BL/6 ES cell line. Mamm Genome. 18:549-558. 
Hurd EA, Capers PL, Blauwkamp MN, Adams ME,  Raphael T, Poucher HK, Martin DM. 2007Loss of Chd7 function in gene-trapped reporter mice is embryonic lethal and associated with severe defects in multiple developing tissues. Mamm. Genome. 18:94-104.
Jain RN, Samuelson LC. 2007Transcriptional Profiling of Gastrin-Regulated Genes in Mouse Stomach. Physiol Genomics. 29;1-12.
Kim I, Saunders TL, Morrison SJ.2007Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. Cell.130:470-483. 
Kim D. Wang M. Cai Q. Brooks H. Dressler GR.2007Pax transactivation-domain interacting protein is required for urine concentration and osmotolerance in collecting duct epithelia. Journal of the American Society of Nephrology. 18:1458-1465.
Lapinski PE, Bauler TJ, Brown EJ, Hughes ED, Saunders TL, King PD. 2007Generation of mice with a conditional allele of the p120 Ras GTPase-activating protein. Genesis. 45:762-767. 
Lehoczky JA, Innis JW. 2007A mouse transgene drives embryonic dorsal posterior commissure expression. Transgenic Res. 16:823-8.
López-Díaz L, Jain RN, Keeley TM, VanDussen KL, Brunkan CS, Gumucio DL, Samuelson LC. 2007Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate. Dev Biol. 309:298-305. 
Lopez-Santiago LF, Meadows LS, Ernst SJ, Chen C, Malhotra JD, McEwen DP, Speelman A, Noebels JL, Maier SK, Lopatin AN, Isom LL. 2007Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals. J Mol Cell Cardiol. 43:636-647. 
Lu B, Geurts AM, Poirier C, Petit DC, Harrison W, Overbeek PA, Bishop CE. 2007Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system. Mamm Genome. 18:338-46.
Matthews RG, Elmore CL. 2007Defects in homocysteine metabolism: diversity among hyperhomocyst(e)inemias. Clin Chem Lab Med. 45:1700-1703.
Nenci A, Becker C, Wullaert A, Gareus R, van Loo G, Danese S, Huth M, Nikolaev A, Neufert C, Madison B, Gumucio D, Neurath MF, Pasparakis M. 2007Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature. 446:557-61.
Newell-Litwa K, Seong E, Burmeister M, Faundez V. 2007Neuronal and non-neuronal functions of the AP-3 sorting machinery. J Cell Sci. 120(Pt 4):531-541. 
Noujaim SF, Pandit SV, Berenfeld O, Vikstrom K, Cerrone M, Mironov S, Zugermayr M, Lopatin AN, Jalife J.2007Up-regulation of the inward rectifier K+ current (IK1) in the mouse heart accelerates and stabilizes rotors. J Physiol. 578(Pt 1):315-26.
Oh EC, Khan N, Novelli E, Khanna H, Strettoi E, Swaroop A. 2007Transformation of cone precursors to functional rod photoreceptors by bZIP transcription factor NRL. PNAS (USA) 104:1679–1684.
Panama BK, McLerie M, Lopatin AN. 2007Heterogeneity of IK1 in the mouse heart. Am J Physiol Heart Circ Physiol. 293:H3558-67. 
Patel SR, Kim D, Levitan I, Dressler GR. 2007The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex.Dev Cell. 13:580-592.
Piao L, Li J, McLerie M, Lopatin AN. 2007Transgenic upregulation of IK1 in the mouse heart is proarrhythmic. Basic Res Cardiol. 102:416-28.
Piao L, Li J, McLerie M, Lopatin AN. 2007Cardiac IK1 underlies early action potential shortening during hypoxia in the mouse heart. J Mol Cell Cardiol. 43:27-38.
Qiao XT. Ziel JW. McKimpson W. Madison BB. Todisco A. Merchant JL. Samuelson LC. Gumucio DL.2007Prospective identification of a multilineage progenitor in murine stomach epithelium. Gastroenterology. 133:1989-1998,
Raven MA, Oh EC, Swaroop A, Reese BE. 2007Afferent control of horizontal cell morphology revealed by genetic respecification of rods and cones. J Neurosci. 27:3540-3547. 
Raetzman LT, Cai JX, Camper SA.  2007Hes1 is required for pituitary growth and melanotrope specification. Dev Biol. 304:455-466.
Ren D, Zhou Y, Morris D, Li M, Li Z, Rui L.2007Neuronal SH2B1 is essential for controlling energy and glucose homeostasis. J Clin Invest. 117:397-406.
Rozeboom AM, Akil H, Seasholtz AF. 2007Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice. Proc Natl Acad Sci U S A.104:4688-4693. 
Savage JJ, Mullen RD, Sloop KW, Colvin SC, Camper SA, Franklin CL, Rhodes SJ.2007Transgenic mice expressing LHX3 transcription factor isoforms in the pituitary: effects on the gonadotrope axis and sex-specific reproductive disease. J Cell Physiol. 212:105-17.
Shen H, Ocheltree SM, Hu Y, Kee, RF, Smith DE.2007Impact of genetic knockout of PEPT2 on cefadroxil pharmacokinetics, renal tubular reabsorption and brain penetration in mice. Drug Metabolism and Disposition.  35: 1209-1216.
Soliman GA, Ishida-Takahashi R, Gong Y, Jones JC, Leshan RL, Saunders TL, Fingar DC, Myers MG Jr. 2007A simple qPCR-based method to detect correct insertion of homologous targeting vectors in murine ES cells. Transgenic Res. 16:665-70. 
Suleiman H, Heudobler D, Raschta AS, Zhao Y, Zhao Q, Hertting I, Vitzthum H, Moeller MJ, Holzman LB, Rachel R, Johnson R, Westphal H, Rascle A, Witzgall R.2007The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes. Dev Biol. 304:701-12.
Wang SH, Arscott P, Wu P, Baker JR Jr.2007No apparent damage in the thyroid of transgenic mice expressing antiapoptotic FLIP. Thyroid. 16:1-8.
Wei Q, Hebda-Bauer EK, Pletsch A, Luo J, Hoversten MT, Osetek AJ, Evans SJ, Watson SJ, Seasholtz AF, Akil H. 2007Overexpressing the glucocorticoid receptor in forebrain causes an aging-like neuroendocrine phenotype and mild cognitive dysfunction. J Neurosci. 37:8836-8844. 
Wiggins RC.2007The spectrum of podocytopathies: A unifying view of glomerular diseases. Kidney Int. 71:1205-14. 
Wright WS, Longo KA, Dolinsky VW, Gerin I, Kang S, Bennett CN, Chiang SH, Prestwich TC, Gress C, Burant CF, Susulic VS, MacDougald OA.2007Wnt10b inhibits obesity in ob/ob and agouti mice. Diabetes. 56:295-303.
Wu J, Rutkowski DT, Dubois M, Swathirajan J, Saunders T, Wang J, Song B, Yau GD, Kaufman RJ. 2007ATF6alpha Optimizes Long-Term Endoplasmic Reticulum Function to Protect Cells from Chronic Stress. Dev Cell. 13:351-64.
Zavros Y, Waghray M, Tessier A, Bai L, Todisco A, L Gumucio D, Samuelson LC, Dlugosz A, Merchant JL. 2007Reduced pepsin A processing of sonic hedgehog in parietal cells precedes gastric atrophy and transformation. J Biol Chem. 282:33265-33274.
Zhu A, Sun H, Raymond RM Jr, Furie BC, Furie B, Bronstein M, Kaufman RJ, Westrick R, Ginsburg D. 2007Fatal hemorrhage in mice lacking {gamma}-glutamyl carboxylase. Blood. 109:5270-5.
Adachi M, Kurotani R, Morimura K, Shah Y, Sanford M, Madison BB, Gumucio DL, Marin HE, Peters JM, Young HA, Gonzalez FJ.2006PPAR{gamma} in colonic epithelial cells protects against experimental inflammatory bowel disease. Gut. 55:1104-13.
Ai D, Liu W, Ma L, Dong F, Lu MF, Wang D, Verzi MP, Cai C, Gage PJ, Evans S, Black BL, Brown NA, Martin JF.2006Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium. Dev Biol. 47:4905-9.
Akimoto M, Cheng H, Zhu D; Brzezinski JA, Khanna R, Filippova E, Oh EC, Jing Y, Linares JL, Brooks M, Zareparsi S, Mears AJ, Hero A, Glaser T, Swaroop A.2006Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors., Proc Natl Acad Sci U S A. 103:3890-3895.
Albertelli MA, Scheller A, Brogley M, Robins DM. 2006Replacing the mouse androgen receptor with human alleles demonstrates glutamine tract length-dependent effects on physiology and tumorigenesis in mice. Mol Endocrinol. 20):1248-1260.
Cai YH, Alvarez A, Alcaide P, Duramad P, Lim YC, Jarolim P, Lowe JB, Luscinskas FW, Lichtman AH.2006Abrogation of functional selectin-ligand expression reduces migration of pathogenic CD8+ T cells into heart. J Immunol. 176:6568-75.
Charles MA, Saunders TL, Wood WM, Owens K, Parlow AF, Camper SA, Ridgway EC, Gordon DF.2006Pituitary-specific gata2 knockout: effects on gonadotrope and thyrotrope function. Mol Endocrinol. 20:1366-1377.
Chauhan AK, Motto DG, Lamb CB, Bergmeier W, Dockal M, Plaimauer B, Scheiflinger F, Ginsburg D, Wagner DD. 2006Systemic antithrombotic effects of ADAMTS13. J Exp Med. 203:767-776.
Cheng H, Aleman TS, Cideciyan AV, Khanna R, Jacobson SG, Swaroop A.2006In vivo function of the orphan nuclear receptor NR2E3 in establishing photoreceptor identity during mammalian retinal development. Hum Mol Genet. 15:2588-602.
Cole JN. McArthur JD. McKay FC. Sanderson-Smith ML. Cork AJ. Ranson M. Rohde M. Itzek A. Sun H. Ginsburg D. Kotb M. Nizet V. Chhatwal GS. Walker MJ.2006Trigger for group A streptococcal M1T1 invasive disease. FASEB Journal. 20:1745-1747
Day SM, Westfall MV, Fomicheva EV, Hoyer K, Yasuda S, La Cross NC, D’Alecy LG, Ingwall JS, Metzger JM.2006Histidine button engineered into cardiac troponin I protects the ischemic and failing heart. Nat Med. 12:181-189.
Deal KK, Cantrell VA, Chandler RL, Saunders TL, Mortlock DP, Southard-Smith EM.2006vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation. Proc Natl Acad Sci U S A.104:12029-34.
Fu Q, Manolagas SC, O’Brien CA. 2006Parathyroid hormone controls receptor activator of NF-kappaB ligand gene expression via a distant transcriptional enhancer. Mol Cell Biol. 26:6453-68.
Diehl AG, Zareparsi S, Qian M, Khanna R, Angeles R, Gage PJ. 2006Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose.Invest Ophthalmol Vis Sci.47:1785-1793.
DobrzynskiH, Billeter R, Greener ID, Tellez JO, Chandler NJ, Flagg TP, Nichols CG, Lopatin AN, Boyett MR.2006Expression of Kir2.1 and Kir6.2 transgenes under the control of the alpha-MHC promoter in the sinoatrial and atrioventricular nodes in transgenic mice. J Mol Cell Cardiol. J Mol Cell Cardiol. 41:855-67.
El-Aouni C, Herbach N, Blattner SM, Henger A, Rastaldi MP, Jarad G, Miner JH, Moeller MJ, St-Arnaud R, Dedhar S, Holzman LB, Wanke R, Kretzler M. 2006Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis. J Am Soc Nephrol. 17:1334-44.
Ellsworth BS, Egashira N, Haller JL, Butts DL, Cocquet J, Clay CM, Osamura RY, Camper SA. 2006FOXL2 in the Pituitary: Molecular, Genetic and Developmental Analysis. Mol Endocrinol. 20:2796-805.
Filipiak WE, Saunders TL. 2006Advances in transgenic rat production. Transgenic Res. 15:673-686.
Foulkes T, Nassar MA, Lane T, Matthews EA, Baker MD, Gerke V, Okuse K, Dickenson AH, Wood JN.2006Deletion of annexin 2 light chain p11 in nociceptorscauses deficits in somatosensory coding and pain behavior. J Neurosci. 26:10499-10507.
Fu Y, Huang X, Zhong H, Mortensen RM, D’Alecy LG, Neubig RR. 2006Endogenous RGS Proteins and G{alpha} Subtypes Differentially Control Muscarinic and Adenosine-Mediated Chronotropic Effects. Circ Res. 98:659-666.
Godovikova V, Li XR, Saunders TL, Ritchie HH. 2006A rat 8 kb dentin sialoprotein-phosphophoryn (DSP-PP) promoter directs spatial and temporal LacZ activity in mouse tissues. Dev Biol. 289:507-16.
Grachtchouk M, Liu J, Wang A, Wei L, Bichakjian CK, Garlick J, Paulino AF, Giordano T, Dlugosz AA. 2006Odontogenic keratocysts arise from quiescent epithelial rests and are associated with deregulated hedgehog signaling in mice and humans. Am J Pathol. 169:806-14. 
Hamstra DA, Bhojani MS, Griffin LB, Laxman B, Ross BD, Rehemtulla A. 2006Real-time evaluation of p53 oscillatory behavior in vivo using bioluminescent imaging. Cancer Res. 66:7482-7489.
Heilig CW, Brosius FC, Cunningham C.2006Role for GLUT1 in diabetic glomerulosclerosis. Expert Rev Mol Med. 8:1-18.
Hiraoka M, Abe A, Lu Y, Yang K, Han X, Gross RW, Shayman JA.2006Lysosomal phospholipase A2 and phospholipidosis. Mol Cell Biol. 26:6139-48.
Huang X, Fu Y, Charbeneau RA, Saunders TL, Taylor DK, Hankenson KD, Russell MW, D’Alecy LG, Neubig RR.2006Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 allele. Mol Cell Biol. 26:6870-9.
Jain RN, Samuelson LC. 2006Differentiation of the gastric mucosa. II. Role of gastrin in gastric epithelial cell proliferation and maturation. Am J Physiol Gastrointest Liver Physiol. 291:G762-5.
Jones RG, Li X, Gray PD, Kuang J, Clayton F, Samowitz WS, Madison BB, Gumucio DL, Kuwada SK. 2006Conditional deletion of beta1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality. J Cell Biol.  175:505-14.
Kanzaki S, Beyer L, Karolyi IJ, Dolan DF, Fang Q, Probst FJ, Camper SA, Raphael Y. 2006Transgene correction maintains normal cochlear structure and function in 6-month-old Myo15a mutant mice. Hear Res. 214:37-44.
Law DJ, Labut EM, Adams RD, Merchant JL. 2006An isoform of ZBP-89 predisposes the colon to colitis. Nucleic Acids Res. 34:1342-1350.
Law DJ, Labut EM, Merchant JL.2006Intestinal overexpression of ZNF148 suppresses Apc(Min)/+ neoplasia. Mamm Genome.17:999-1004.
Lehoczky JA, Cai WW, Douglas JA, Moran JL, Beier DR, Innis JW.2006Description and genetic mapping of Polypodia: an X-linked dominant mouse mutant with ectopic caudal limbs and other malformations. Mamm Genome. 17:903-13.
Leshan RL, Björnholm M, Münzberg H, Myers MG Jr.2006Leptin receptor signaling and action in the central nervous system. Obesity (Silver Spring). 14 Suppl 5:208S-212S.
Levin SI, Khaliq ZM, Aman TK, Grieco TM, Kearney JA, Raman IM, Meisler MH. 2006Impaired motor function in mice with cell-specific knockout of Na channel Scn8a (NaV1.6) in cerebellar Purkinje neurons and granule cells. J Neurophysiol. 96:785-93.
Li B, Duysen EG, Saunders TL, Lockridge O. 2006Production of the butyrylcholinesterase knockout mouse. J Mol Neurosci. 30:193-6. 
Li M, Ren D, Iseki M, Takaki S, Rui L. 2006Differential Role of SH2-B and APS in Regulating Energy and Glucose Homeostasis. Endocrinology. 147:2163-2170.
Lin J, Patel SLin J, Patel SR, Wang M, Dressler GR.2006The cysteine-rich domain protein KCP is a suppressor of transforming growth factor beta/activin signaling in renal epithelia. Mol Cell Biol. 26:4577-85.
Lopez-Diaz L, Hinkle KL, Jain RN, Zavros Y, Brunkan CS, Keeley T, Eaton KA, Merchant JL, Chew CS, Samuelson LC. 2006Parietal Cell Hyperstimulation and Autoimmune Gastritis in Cholera Toxin Transgenic Mice.  Am J Physiol Gastrointest Liver Physiol. 290:G970-979.
Lopez-Santiago LF, Pertin M, Morisod X, Chen C, Hong S, Wiley J, Decosterd I, Isom LL. 2006Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain. J Neurosci. 26:7984-94.
Ma J, Zeng F, Schultz RM, Tseng H. 2006Basonuclin: a novel mammalian maternal-effect gene. Development. 133:2053-2062.
MacLaren RE, Pearson RA, MacNeil A, Douglas RH, Salt TE, Akimoto M, Swaroop A, Sowden JC, Ali RR. 2006Retinal repair by transplantation of photoreceptor precursors. Nature. 444:203-7.
Nowotschin S, Liao J, Gage PJ, Epstein JA, Campione M, Morrow BE.2006Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field. Development. 133:1565-73. 
Pasca di Magliano M, Sekine S, Ermilov A, Ferris J, Dlugosz AA, Hebrok M. 2006Hedgehog/Ras interactions regulate early stages of pancreatic cancer. Genes Dev. 20:3161-3173. 
Raetzman LT, Wheeler BS, Ross SA, Thomas PQ, Camper SA. 2006Persistent expression of Notch2 delays gonadotrope differentiation. Mol Endocrinol. 20:2898-90.
Reiley WW, Zhang M, Jin W, Losiewicz M, Donohue KB, Norbury CC, Sun S-C.2006Regulation of T cell development by the deubiquitinating enzyme CYLD. Nature Immunology 7:411 –417.
Rosen ED, Macdougald OA. 2006Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol. 7:885-96.
Sarapura VD, Wood WM, Woodmansee WW, Haakinson DJ, Dowding JM, Gordon DF, Ridgway EC. 2006ituitary tumors arising from glycoprotein hormone alpha-subunit-deficient mice contain transcription factors and receptors present in thyrotropes. Pituitary. 9:1-8.
Schreiber T, Ehlers S, Aly S, Holscher A, Hartmann S, Lipp M, Lowe JB, Holscher C. 2006Selectin ligand-independent priming and maintenance of T cell immunity during airborne tuberculosis. J Immunol. 176:1131-1140.
Sclafani AM, Skidmore JM, Ramaprakash H, Trumpp A, Gage PJ, Martin DM.2006Nestin-Cre mediated deletion of Pitx2 in the mouse. Genesis. 44:336-44.
Shen Y, Bodary PF, Vargas FB, Homeister JW, Gordon D, Ostenso KA, Shayman JA, Eitzman DT. 2006Alpha-galactosidase A deficiency leads to increased tissue fibrin deposition and thrombosis in mice homozygous for the factor V Leiden mutation. Stroke. 37:1106-1108.
Simeone DM, Zhang L, Treutelaar MK, Zhang L, Graziano K, Logsdon CD, Burant CF. 2006Islet Hypertrophy Following Pancreatic Disruption of Smad4 Signaling. Am J Physiol Endocrinol Metab. 291:E12305-16.
St John JA, Claxton C, Robinson MW, Yamamoto F, Domino SE, Key B.2006Genetic manipulation of blood group carbohydrates alters development and pathfinding of primary sensory axons of the olfactory systems. Dev Biol. 298:470-84.
Wang SH. Arscott P. Wu P. Baker JR Jr.2006No apparent damage in the thyroid of transgenic mice expressing antiapoptotic FLIP. Thyroid. 16:1-8,
Ward RD, Davis SW, Cho M, Esposito C, Lyons RH, Cheng JF, Rubin EM, Rhodes SJ, Raetzman LT, Smith TP, Camper SA.2006Comparative genomics reveals functional transcriptional control sequences in the Prop1 gene. Mamm Genome. 18:521-537. 
Westphal NJ, Seasholtz AF.2006CRH-BP: the regulation and function of a phylogenetically conserved binding protein. Front Biosci.11:1878-91.
Wilkinson Iv J, Di X, Schonig K, Buss JL, Kock ND, Cline JM, Saunders TL, Bujard H, Torti SV, Torti FM. 2006Tissue-specific expression of ferritin H regulates cellular iron homeostasis in vivo. Biochem J. 395:501-507.
Williams ME, Lehoczky JA, Innis JW. 2006A group 13 homeodomain is neither necessary nor sufficient for posterior prevalence in the mouse limb. Dev Biol. 297:493-507.
Woodruff-Pak DS, Green JT, Levin SI, Meisler MH. 2006Inactivation of sodium channel Scn8A (Na-sub(v)1.6) in Purkinje neurons impairs learning in Morris water maze and delay but not trace eyeblink classical conditioning. Behav Neurosci. 120:229-240. 
Xiang J, Chiang PP, Hu Y, Smith DE, Keep RF.2006Role of PEPT2 in glycylsarcosine transport in astrocyte and glioma cultures. Neurosci Lett. 396:225-9. 
Xiang J, Hu Y, Smith DE, Keep RF. 2006PEPT2-mediated transport of 5-aminolevulinic acid and carnosine in astrocytes. Brain Res. 1122:18-23.
Yu Z, Dadgar N, Albertelli M, Gruis K, Jordan C, Robins DM, Lieberman AP. 2006Androgen-dependent pathology demonstrates myopathic contribution to the Kennedy disease phenotype in a mouse knock-in model. J Clin Invest. 116:2663-72.
Yu Z, Dadgar N, Albertelli M, Scheller A, Albin RL, Robins DM, Lieberman AP.2006Abnormalities of Germ Cell Maturation and Sertoli Cell Cytoskeleton in Androgen Receptor 113 CAG Knock-In Mice Reveal Toxic Effects of the Mutant Protein.  Am J Pathol. 168:195-204.
Zhang HZ, Degar BA, Rogoulina S, Resor C, Booth CJ, Sinning J, Gage PJ, Forget BG.2006Hematopoiesis following disruption of the Pitx2 homeodomain gene. Exp Hematol. 34:167-78.
Zhang K, Shen X, Wu J, Sakaki K, Saunders T, Rutkowski DT, Back SH, Kaufman RJ.2006Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Cell. 124:587-599.
Zhu M, Lovell KL, Patterson JS, Saunders TL, Hughes ED, Friderici KH. 2006{beta}-Mannosidosis mice: a model for the human lysosomal storage disease. Hum Mol Genet. 15:493-500.
Bennett CN, Longo KA, Wright WS, Suva LJ, Lane TF, Hankenson KD, MacDougald OA. 2005Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A. 102:3324-3329.
Brzezinski JA 4th, Brown NL, Tanikawa A, Bush RA, Sieving PA, Vitaterna MH, Takahashi JS, Glaser T.2005Loss of circadian photoentrainment and abnormal retinal electrophysiology in math5 mutant mice.  Invest Ophthalmol Vis Sci. 46:2540-2551.
Charles MA, Suh H, Hjalt TA, Drouin J, Camper SA, Gage PJ.2005PITX genes are required for cell survival and Lhx3 activation. Mol Endocrinol.  19:1893-903.
Daniele LL, Lillo C, Lyubarsky AL, Nikonov SS, Philp N, Mears AJ, Swaroop A, Williams DS, Pugh EN Jr.2005Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse. Invest Ophthalmol Vis Sci.46:2156-67.
Dunnick WA, Shi J, Graves KA, Collins JT. 2005The 3′ end of the heavy chain constant region locus enhances germline transcription and switch recombination of the four gamma genes. J Exp Med. 201:1459-66.
Eitzman DT, Westrick RJ, Shen Y, Bodary PF, Gu S, Manning SL, Dobies SL, Ginsburg D.2005Homozygosity for Factor V Leiden Leads to Enhanced Thrombosis and Atherosclerosis in Mice. Circulation. 111:1822-5.
Evans AL, Gage PJ.2005Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development. Hum Mol Genet. 15:3347-3359.
Flagg TP, Remedi MS, Masia R, Gomes J, McLerie M, Lopatin AN, Nichols CG. 2005Transgenic overexpression of SUR1 in the heart suppresses sarcolemmal K(ATP). J Mol Cell Cardiol. 39:647-56.
Gage PJ, Rhoades W, Prucka SK, Hjalt T. 2005Fate maps of neural crest and mesoderm in the mammalian eye. Invest Ophthalmol Vis Sci. 46:4200-8.
Ginsburg D.2005Identifying novel genetic determinants of hemostatic balance. J Thromb Haemost. 8:1561-8.
Hammer GD, Parker KL, Schimmer BP. 2005Minireview: transcriptional regulation of adrenocortical development. Endocrinology.146:1018-24.
Hurd EA, Holmen JM, Hansson GC, Domino SE. 2005Gastrointestinal Mucins of Fut2-Null Mice Lack Terminal Fucosylation without Affecting Colonization by Candida albicans. Glycobiology. 15:1002-1007.
Hutchin ME, Kariapper MS, Grachtchouk M, Wang A, Wei L, Cummings D, Liu J, Michael LE, Glick A, Dlugosz AA. 2005Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle. Genes Dev. 19:214-223.
Jain RN, Brunkan CS, Chew CS, Samuelson LC. 2005Gene Expression Profiling of Gastrin Target Genes in Parietal Cells. Physiol Genomics. 24:124-32
Kang S, Bajnok L, Longo KA, Petersen RK, Hansen JB, Kristiansen K, MacDougald OA.2005Effects of Wnt signaling on brown adipocyte differentiation and metabolism mediated by PGC-1alpha. Mol Cell Biol. 25:1272-82. 
Kang W, Rathinavelu S, Samuelson LC, Merchant JL. 2005Interferon gamma induction of gastric mucous neck cell hypertrophy. Lab Invest. 85:702-715.
Keegan CE, Hutz JE, Else T, Adamska M, Shah SP, Kent AE, Howes JM, Beamer WG, Hammer GD. 2005Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator. Hum Mol Genet. 14:113-23.
Kieusseian A, Chagraoui J, Kerdudo C, Mangeot PE, Gage PJ, Navarro N, Izac B, Uzan G, Forget BG, Dubart-Kupperschmitt A. 2005Expression of Pitx2 in stromal cells is required for normal hematopoiesis. Blood. 107:492-500.
Kurachi K, Kurachi S.2005Molecular mechanisms of age-related regulation of genes. J Thromb Haemost. 3:909-914.
Lay JM, Bane G, Brunkan CS, Davis J, Lopez-Diaz L, Samuelson LC. 2005Enteroendocrine cell expression of a cholecystokinin gene construct in transgenic mice and cultured cells. Am J Physiol Gastrointest Liver Physiol. 288:G354-61.
Lin J, Patel SR, Cheng X, Cho EA, Levitan I, Ullenbruch M, Phan SH, Park JM, Dressler GR.2005Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease. Nat Med. 11:387-93.
Madison BB, Braunstein K, Kuizon E, Portman K, Qiao XT, Gumucio DL. 2005Epithelial hedgehog signals pattern the intestinal crypt-villus axis. Development. 132:279-89.
McEwen E, Kedersha N, Song B, Scheuner D, Gilks N, Han A, Chen JJ, Anderson P, Kaufman RJ. 2005Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure. J Biol Chem. 280:16925-33.
McInerney GM, Kedersha NL, Kaufman RJ, Anderson P, Liljestrom P.2005Importance of eIF2alpha phosphorylation and stress granule assembly in alphavirus translation regulation. Mol Biol Cell. 16:3753-63.
Meadows LS, Isom LL. 2005Sodium channels as macromolecular complexes: Implications for inherited arrhythmia syndromes.  Cardiovasc Res. 67:448-58.
Meehan TP, Harmon BG, Overcast ME, Yu KK, Camper SA, Puett D, Narayan P.2005Gonadal defects and hormonal alterations in transgenic mice expressing a single chain human chorionic gonadotropin-lutropin receptor complex. J Mol Endocrinol. 34:489-503.
Moeller MJ, Soofi A, Sanden SK, Floege J, Kriz W, Holzman LB.2005An efficient system for tissue-specific over-expression of transgenes in podocytes in vivo. Am J Physiol Renal Physiol. 289:F481-8.
Molinari M, Galli C, Vanoni O, Arnold SM, Kaufman RJ.2005Persistent glycoprotein misfolding activates the glucosidase II/UGT1-driven calnexin cycle to delay aggregation and loss of folding competence. Mol Cell. 20:503-12.
Motto DG, Chauhan AK, Zhu G, Homeister J, Lamb CB, Desch KC, Zhang W, Tsai HM, Wagner DD, Ginsburg D. 2005Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice.  J Clin Invest. 115:2752-61.
Nabulsi NB, Smith DE, Kilbourn MR. 2005[(11)C]Glycylsarcosine: synthesis and in vivo evaluation as a PET tracer of PepT2 transporter function in kidney of PepT2 null and wild-type mice. Bioorg Med Chem. 13:2993-3001.
Nikonov SS, Daniele LL, Zhu X, Craft CM, Swaroop A, Pugh EN Jr. 2005Photoreceptors of Nrl -/- mice coexpress functional S- and M-cone opsins having distinct inactivation mechanisms. J Gen Physiol. 125:287-304.
Ocheltree SM, Shen H, Hu Y, Keep RF, Smith DE.2005Role and relevance of peptide transporter 2 (PEPT2) in the kidney and choroid plexus: in vivo studies with glycylsarcosine in wild-type and PEPT2 knockout mice. J Pharmacol Exp Ther. 31:240-7.
Park SY, Meeks JJ, Raverot G, Pfaff LE, Weiss J, Hammer GD, Jameson JL. 2005Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development. Development. 132:2415-23.
Piccio L, Rossi B, Colantonio L, Grenningloh R, Gho A, Ottoboni L, Homeister JW, Scarpini E, Martinello M, Laudanna C, D’Ambrosio D, Lowe JB, Constantin G. 2005Efficient recruitment of lymphocytes in inflamed brain venules requires expression of cutaneous lymphocyte antigen and fucosyltransferase-VII. J Immunol. 174:5805-13.
Ren D, Li M, Duan C, Rui L. 2005Identification of SH2-B as a key regulator of leptin sensitivity, energy balance, and body weight in mice. Cell Metab. 2:95-104.
Rieder G, Tessier AJ, Qiao XT, Madison B, Gumucio DL, Merchant JL.2005Helicobacter-induced intestinal metaplasia in the stomach correlates with Elk-1 and serum response factor induction of villin. J Biol Chem. 280:4906-12.
Roessler E, Ermilov AN, Grange DK, Wang A, Grachtchouk M, Dlugosz AA, Muenke M. 2005A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2. Hum Mol Genet. 14:2181-2188.
Satoh T, Kanai Y, Wu MH, Yokozeki H, Kannagi R, Lowe JB, Nishioka K.2005Synthesis of {alpha}(1,3) Fucosyltransferases IV- and VII-Dependent Eosinophil Selectin Ligand and Recruitment to the Skin. Am J Pathol. 167:787-96.
Scheuner D, Mierde DV, Song B, Flamez D, Creemers JW, Tsukamoto K, Ribick M, Schuit FC, Kaufman RJ. 2005Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis. Nat Med. 11:757-64.
Seong E, Wainer BH, Hughes ED, Saunders TL, Burmeister M, Faundez V. 2005Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain. Mol Biol Cell. 16:128-40.
Shen H, Keep RF, Hu Y, Smith DE. 2005PEPT2 (Slc15a2)-Mediated Unidirectional Transport of Cefadroxil from Cerebrospinal Fluid into Choroid Plexus. J Pharmacol Exp Ther. 315:1101-8.
Siegmund K, Feuerer M, Siewert C, Ghani S, Haubold U, Dankof A, Krenn V, Schon MP, Scheffold A, Lowe JB, Hamann A, Syrbe U, Huehn J. 2005Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo. Blood. 106:3097-104.
van den Buuse M, van Driel IR, Samuelson LC, Pijnappel M, Martin S.2005Reduced effects of amphetamine on prepulse inhibition of startle in gastrin-deficient mice. Neurosci Lett. 373:237-42.
Vesper AH, Raetzman LT, Camper SA. 2005Role of PROP1 in gonadotrope differentiation and puberty. Endocrinology. 147:1654-1663.
Ward RD, Raetzman LT, Suh H, Stone BM, Nasonkin IO, Camper SA.2005Role of PROP1 in pituitary gland growth. Mol Endocrinol. 19:698-710.
Wharram BL, Goyal M, Wiggins JE, Sanden SK, Hussain S, Filipiak WE, Saunders TL, Dysko RC, Kohno K, Holzman LB, Wiggins RC. 2005Podocyte Depletion Causes Glomerulosclerosis: Diphtheria Toxin-Induced Podocyte Depletion in Rats Expressing Human Diphtheria Toxin Receptor Transgene. J Am Soc Nephrol. J Am Soc Nephrol.16:2941-52.
Xiang J, Chiang PP, Hu Y, Smith DE, Keep RF. 2005Role of PEPT2 in glycylsarcosine transport in astrocyte and glioma cultures. Neurosci Lett. 396:225-9.
Zavros Y, Eaton KA, Kang W, Rathinavelu S, Katukuri V, Kao JY, Samuelson LC, Merchant JL. 2005Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinoma. Oncogene. 24:2354-66.
Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ. 2005The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis. J Clin Invest. 115:268-81.
Adamska M, MacDonald BT, Sarmast ZH, Oliver ER, Meisler MH. 2004En1 and Wnt7a interact with Dkk1 during limb development in the mouse. Dev Biol.272:134-44.
Akimoto M, Filippova E, Gage PJ, Zhu X, Craft CM, Swaroop A.2004Transgenic mice expressing Cre-recombinase specifically in M- or S-cone photoreceptors. Invest Ophthalmol Vis Sci.45:42-7.
Berton MT, Linehan LA, Wick KR, Dunnick WA.2004NF-kappaB elements associated with the Stat6 site in the germline gamma1 immunoglobulin promoter are not necessary for the transcriptional response to CD40 ligand. Int Immunol. 16:1741-9. 
Chen C, Westenbroek RE, Xu X, Edwards CA, Sorenson DR, Chen Y, McEwen DP, O’Malley HA, Bharucha V, Meadows LS, Knudsen GA, Vilaythong A, Noebels JL, Saunders TL, Scheuer T, Shrager P, Catterall WA, Isom LL. 2004Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture. J Neurosci. 24:4030-4042.
Chen D, Zhao CM, Hakanson R, Samuelson LC, Rehfeld JF, Friis-Hansen L.2004Altered control of gastric acid secretion in gastrin-cholecystokinin double mutant mice. Gastroenterology. 2004 126:476-87.
Dang L, Pulukuri S, Mears AJ, Swaroop A, Reese BE, Sitaramayya A.2004Connexin 36 in photoreceptor cells: studies on transgenic rod-less and cone-less mouse  retinas. Mol Vis. 10:323-7.
Davis TH, Chen C, Isom LL.2004Sodium channel beta1 subunits promote neurite outgrowth in cerebellar granule neurons. J Biol Chem. 279:51424-32.
Domino SE, Hurd EA. 2004LacZ expression in Fut2-LacZ reporter mice reveals estrogen-regulated endocervical glandular expression during estrous cycle, hormone replacement, and pregnancy. Glycobiology. 14:169-75.
Duan C, Yang H, White MF, Rui L. 2004Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance. Mol Cell Biol. 17:7435-43.
Dunnick WA, Shi J, Graves KA, Collins JT.2004Germline transcription and switch recombination of a transgene containing the entire H chain constant region locus: effect of a mutation in a STAT6 binding site in the gamma 1 promoter. J Immunol.  Nov 1;173(9):5531-9.
Franic TV, Judd M, Nguyen NV, Samuelson LC, Loveland KL, Giraud AS, Gleeson PA, Van Driel IR.2004Growth factors associated with gastric mucosal hypertrophy in autoimmune gastritis. Am J Physiol Gastrointest Liver Physiol.  287:G910-8.
Fu Y, Zhong H, Nanamori M, Mortensen RM, Huang X, Lan K, Neubig RR. 2004RGS-insensitive G-protein mutations to study the role of endogenous RGS proteins. Methods Enzymol. 389:229-43
Homeister JW, Daugherty A, Lowe JB. 2004{alpha}(1,3)Fucosyltransferases FucT-IV and FucT-VII Control Susceptibility to Atherosclerosis in Apolipoprotein E-/- Mice. Arterioscler Thromb Vasc Biol. 24:1897-903.
Hurd, EA., Domino, SE. 2004Increased susceptibility of secretor factor gene Fut2-null mice to experimental vaginal candidiasis. Infect Immun. 72:4279-81.
Hyun TS, Li L, Oravecz-Wilson KI, Bradley SV, Provot MM, Munaco AJ, Mizukami IF, Sun H, Ross TS.2004Hip1-related mutant mice grow and develop normally but have accelerated spinal abnormalities and dwarfism in the absence of HIP1. Mol Cell Biol. 24:4329-40.
Imaizumi K, Benito A, Kiryu-Seo S, Gonzalez V, Inohara N, Leiberman AP, Kiyama H, Nunez G.2004Critical role for DP5/Harakiri, a Bcl-2 homology domain 3-only Bcl-2 family member, in axotomy-induced neuronal cell death. J Neurosci. 24:3721-5.
Iwamori M, Domino SE.2004Tissue-specific loss of fucosylated glycolipids in mice with targeted deletion of alpha(1,2)fucosyltransferase genes.Biochem J.380:75-81.
Jiang D, Franceschi RT, Boules H, Xiao G. 2004Parathyroid hormone induction of the osteocalcin gene. Requirement for an osteoblast-specific element 1 sequence in the promoter and involvement of multiple-signaling pathways. J Biol Chem. 279:5329-37.
Kaur S, Norkina O, Ziemer D, Samuelson LC, De Lisle RC.2004Acidic duodenal pH alters gene expression in the cystic fibrosis mouse pancreas. Am J Physiol Gastrointest Liver Physiol. 287:G480-90.
Kubisch C, Dimagno MJ, Tietz AB, Welsh MJ, Ernst SA, Brandt-Nedelev B, Diebold J, Wagner AC, Goke B, Williams JA, Schafer C. 2004Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis. Gastroenterology.  127:275-86.
Lehoczky JA, Williams ME, Innis JW. 2004Conserved expression domains for genes upstream and within the HoxA and HoxD clusters suggests a long-range enhancer existed before cluster duplication. Evol Dev. 6:423-30.
Levin SI, Meisler MH. 2004Floxed allele for conditional inactivation of the voltage-gated sodium channel Scn8a (Na(v)1.6). Genesis. 39:234-9.
Li J, McLerie M, Lopatin AN. 2004Transgenic Up-Regulation of IK1 in The Mouse Heart Leads to Multiple Abnormalities of Cardiac Excitability. Am J Physiol Heart Circ Physiol. 287:H2790-80.
Longo KA, Wright WS, Kang S, Gerin I, Chiang SH, Lucas PC, Opp MR, MacDougald OA. 2004Wnt10b inhibits development of white and brown adipose tissues. J Biol Chem. 279(34):35503-9.
MacDonald BT, Adamska M, Meisler MH. 2004Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6. Development. 131:2543-52.
Martin DM, Skidmore JM, Philips ST, Vieira C, Gage PJ, Condie BG, Raphael Y, Martinez S, Camper SA.2004PITX2 is required for normal development of neurons in the mouse subthalamic nucleus and midbrain. Dev Biol. 267:93-108.
Martins RP, Ostermeier GC, Krawetz SA.2004Nuclear matrix interactions at the human protamine domain: a working model of potentiation. J Biol Chem. 279:51862-8.
Moeller MJ, Soofi A, Hartmann I, Le Hir M, Wiggins R, Kriz W, Holzman LB. 2004Podocytes populate cellular crescents in a murine model of inflammatory  glomerulonephritis. J Am Soc Nephrol. 15:61-7.
Nasonkin IO, Ward RD, Raetzman LT, Seasholtz AF, Saunders TL, Gillespie PJ, Camper SA. 2004Pituitary hypoplasia and respiratory distress syndrome in Prop1 knockout mice. Hum Mol Genet. 13(22):2727-35.
Ocheltree SM, Shen H, Hu Y, Xiang J, Keep RF, Smith DE.2004Mechanisms of cefadroxil uptake in the choroid plexus: studies in wild-type and PEPT2 knockout mice. J Pharmacol Exp Ther. 308:462-7.
Ocheltree SM, Shen H, Hu Y, Xiang J, Keep RF, Smith DE. 2004Role of PEPT2 in the choroid plexus uptake of glycylsarcosine and 5-aminolevulinic acid: studies in wild-type and null mice. Pharm Res. 21:1680-5.
Oliver ER, Saunders TL, Tarle SA, Glaser T. 2004Ribosomal protein L24 defect in Belly spot and tail (Bst), a mouse Minute. Development. 131:3907-20.
Oravecz-Wilson KI, Kiel MJ, Li L, Rao DS, Saint-Dic D, Kumar PD, Provot MM, Hankenson KD, Reddy VN, Lieberman AP, Morrison SJ, Ross TS. 2004 Huntingtin Interacting Protein 1 mutations lead to abnormal hematopoiesis, spinal defects and cataracts. Hum Mol Genet. 13:851-67.
Patel SR, Dressler GR. 2004Expression of Pax2 in the intermediate mesoderm is regulated by YY1. Dev Biol. 267:505-16.
Parker AC, Mundada LV, Schmaier AH, Fay WP. 2004Factor V Leiden inhibits fibrinolysis in vivo. Circulation. 110:3594-8.
Pittler SJ, Zhang Y, Chen S, Mears AJ, Zack DJ, Ren Z, Swain PK, Yao S, Swaroop A, White JB.2004Functional analysis of the rod photoreceptor cGMP phosphodiesterase alpha-subunit gene promoter: Nrl and Crx are required for full transcriptional activity. J Biol Chem. 179:19800-7.
Raetzman LT, Ross SA, Cook S, Dunwoodie SL, Camper SA, Thomas PQ.2004Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression. Dev Biol.265:329-40.
Sun H, Ringdahl U, Homeister JW, Fay WP, Engleberg NC, Yang AY, Rozek LS, Wang X, Sjobring U, Ginsburg D. 2004Plasminogen is a critical host pathogenicity factor for group A streptococcal infection. Science. 305:1283-6.
Seong E, Saunders TL, Stewart CL, Burmeister M.2004To knockout in 129 or in C57BL/6: that is the question. Trends Genet. 20:59-62.
Strettoi E, Mears AJ, Swaroop A. 2004Recruitment of the rod pathway by cones in the absence of rods. J Neurosci. 24:7576-82.
Teuscher NS, Shen H, Shu C, Xiang J, Keep RF, Smith DE. 2004Carnosine uptake in rat choroid plexus primary cell cultures and choroid plexus whole tissue from PEPT2 null mice. J Neurochem. 91:1024.
Teuscher NS, Shen H, Shu C, Xiang J, Keep RF, Smith DE. 2004Carnosine uptake in rat choroid plexus primary cell cultures and choroid plexus whole tissue from PEPT2 null mice. J Neurochem. 89:375-82.
Van Keuren ML, Saunders TL. 2004Rederivation of Transgenic and Gene-Targeted Mice by Embryo Transfer. Transgenic Res. 13:363-371.
Wang Y, Boeck AT, Duysen EG, Van Keuren M, Saunders TL, Lockridge O. 2004Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase. Toxicol Appl Pharmacol. 196:356-66.
Wei Q, Lu XY, Liu L, Schafer G, Shieh KR, Burke S, Robinson TE, Watson SJ, Seasholtz AF, Akil H. 2004Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. Proc Natl Acad Sci U S A. 101:11851-6.
Adamska M, MacDonald BT, Meisler MH. 2003Doubleridge, a mouse mutant with defective compaction of the apical ectodermal ridge and normal dorsal-ventral patterning of the limb. Dev Biol. 2003 Mar 15;255(2):350-62.
Ameri A, Kurachi S, Sueishi K, Kuwahara M, Kurachi K. 2003Myocardial fibrosis in mice with overexpression of human blood coagulation factor IX. Blood. 101(5):1871-3.
Becker DJ, Myers JT, Ruff MM, Smith PL, Gillespie BW, Ginsburg DW, Lowe JB.2003Strain-specific modification of lethality in fucose-deficient mice. Mamm Genome. 14:130-9.
Ben-Yosef T, Belyantseva IA, Saunders TL, Hughes ED, Kawamoto K, Van Itallie CM, Beyer LA, Halsey K, Gardner DJ, Wilcox ER, Rasmussen J, Anderson JM, Dolan DF, Forge A, Raphael Y, Camper SA, Friedman TB. 2003Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration. Hum Mol Genet. 12(16):2049-2061.
Cho EA, Prindle MJ, Dressler GR. 2003BRCT domain-containing protein PTIP is essential for progression through mitosis. Mol Cell Biol. 23:1666-73.
Gopalakrishnan R, Thomas PE, Benson MD, Wang D, Franceschi RT. 2003A homeodomain protein binding element in the bone sialoprotein promoter is critical for tissue-specific expression in bone. Connect Tissue Res. 44:154-60.
Grachtchouk V, Grachtchouk M, Lowe L, Johnson T, Wei L, Wang A, de Sauvage F, Dlugosz AA.2003The magnitude of hedgehog signaling activity defines skin tumor phenotype.EMBO J. 22:2741-51.
Heilig CW, Saunders T, Brosius FC 3rd, Moley K, Heilig K, Baggs R, Guo L, Conner D.2003Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy. Proc Natl Acad Sci U S A.100:15613-8. 
Hinkle KL, Bane GC, Jazayeri A, Samuelson LC. 2003Enhanced calcium signaling and acid secretion in parietal cells isolated from gastrin-deficient mice. Am J Physiol Gastrointest Liver Physiol. 284(1):G145-53.
Jahroudi N, Schmaier A, Srikanth S, Mahdi F, Lutka FA, Bowser R.2003Von Willebrand factor promoter targets the expression of amyloid beta protein precursor to brain vascular endothelial cells of transgenic mice. J Alzheimers Dis. 5:149-58.
Jones JM, Datta P, Srinivasula SM, Ji W, Gupta S, Zhang Z, Davies E, Hajnoczky G, Saunders TL, Van Keuren ML, Fernandes-Alnemri T, Meisler MH, Alnemri ES. 2003Nature. 425:721-7.
Krebs CJ, Larkins LK, Price R, Tullis KM, Miller RD, Robins DM. 2003Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression. Genes Dev. 17:2664-74.
Marcil A, Dumontier E, Chamberland M, Camper SA, Drouin J.2003Pitx1 and Pitx2 are required for development of hindlimb buds. Development. 130:45-55.
McLerie M, Lopatin A.2003Dominant-negative suppression of I(K1) in the mouse heart leads to altered cardiac excitability. J Mol Cell Cardiol. 35:367-78.
Mill P, Mo R, Fu H, Grachtchouk M, Kim PC, Dlugosz AA, Hui CC.2003Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. Genes Dev. 17:282-94.
Moeller MJ, Sanden SK, Soofi A, Wiggins RC, Holzman LB.2003Podocyte-specific expression of cre recombinase in transgenic mice. Genesis. 35(1):39-42.
Norman LP, Jiang W, Han X, Saunders TL, Bond JS.2003Targeted disruption of the meprin Beta gene in mice leads to underrepresentation of knockout mice and changes in renal gene expression profiles. Mol Cell Biol. (4):1221-30.
Samuelson LC, Hinkle KL. 2003Insights into the regulation of gastric Acid secretion through analysis of genetically engineered mice. Annu Rev Physiol. 65:383-400.
Saunders TL.2003Reporter molecules in genetically engineered mice. Methods Mol Biol. 209:125-43.
Shen H, Smith DE, Keep RF, Xiang J, Brosius FC 3rd. 2003Targeted disruption of the PEPT2 gene markedly reduces dipeptide uptake in choroid plexus. J Biol Chem. 278(7):4786-91.
Shigehara T, Zaragoza C, Kitiyakara C, Takahashi H, Lu H, Moeller M, Holzman LB, Kopp JB.2003Inducible podocyte-specific gene expression in transgenic mice. J Am Soc Nephrol. 14:1998-2003.
Sun FJ, Kaur S, Ziemer D, Banerjee S, Samuelson LC, De Lisle RC. 2003Decreased gastric bacterial killing and up-regulation of protective genes in small intestine in gastrin-deficient mouse. Dig Dis Sci. 48:976-85.
Sun H, Yang TL, Yang A, Wang X, Ginsburg D. 2003The murine platelet and plasma factor V pools are biosynthetically distinct and sufficient for minimal hemostasis. Blood. 102:2856-61.
Swain JE, Wang X, Saunders TL, Dunn R, Smith GD. 2003Specific inhibition of mouse oocyte nuclear protein phosphatase-1 stimulates germinal vesicle breakdown. Mol Reprod Dev. 65:96-103.
Van Mater D, Kolligs FT, Dlugosz AA, Fearon ER. 2003Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice. Genes Dev. 17:1219-24.
Yang TL, Pipe SW, Yang A, Ginsburg D.2003Biosynthetic origin and functional significance of murine platelet factor V. Blood. 102:2851-5.
Babu PS, Bavers DL, Beuschlein F, Shah S, Jeffs B, Jameson JL, Hammer GD. 2002Interaction between Dax-1 and steroidogenic factor-1 in vivo: increased adrenal responsiveness to ACTH in the absence of Dax-1.  Endocrinology. 143(2):665-73.
Braunstein EM, Qiao XT, Madison B, Pinson K, Dunbar L, Gumucio DL. 2002Villin: A marker for development of the epithelial pyloric border. Dev Dyn. 224:90-102.
Chen C, Bharucha V, Chen Y, Westenbroek RE, Brown A, Malhotra JD, Jones D, Avery C, Gillespie PJ 3rd, Kazen-Gillespie KA, Kazarinova-Noyes K, Shrager P, Saunders TL, Macdonald RL, Ransom BR, Scheuer T, Catterall WA, Isom LL. 2002Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits. Proc Natl Acad Sci U S A. 99: 17072-17027.
Eitzman DT, Westrick RJ, Bi X, Manning SL, Wilkinson JE, Broze GJ, Ginsburg D. 2002Lethal perinatal thrombosis in mice resulting from the interaction of tissue factor pathway inhibitor deficiency and factor V Leiden. Circulation. 105(18):2139-42.
Erdmann I, Scheidegger EP, Koch FK, Heinzerling L, Odermatt B, Burg G, Lowe JB, Kundig TM. 2002Fucosyltransferase VII-deficient mice with defective E-, P-, and L-selectin ligands show impaired CD4+ and CD8+ T cell migration into the skin, but normal extravasation into visceral organs. J Immunol. 168: 2139-2146.
Innis JW, Margulies EH, Kardia S. 2002Integrative biology and the developing limb bud. Evol Dev. 4: 378-389.
Ishida S, Lee J, Thiele DJ, Herskowitz I. 2002Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals. Proc Natl Acad Sci U S A. 99:14298-302.
Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ. 2002IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev. 16:452-66.
Lee J, Petris MJ, Thiele DJ. 2002Characterization of mouse embryonic cells deficient in the Ctr1 high affinity copper transporter: Identification of a Ctr1-independent copper system. J Biol Chem. 277:40253-9.
Madison BB, Dunbar L, Qiao XT, Braunstein KA, Braunstein EM, Gumucio DL. 2002Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine. J Biol Chem. J Biol Chem. 277:33275-83.
Martin DM, Skidmore JM, Fox SE, Gage PJ, Camper SA.2002Pitx2 distinguishes subtypes of terminally differentiated neurons in the developing mouse neuroepithelium. Dev Biol. 252:84-99.
Michele DE, Gomez CA, Hong KE, Westfall MV, Metzger JM.2002Cardiac dysfunction in hypertrophic cardiomyopathy mutant tropomyosin mice is transgene-dependent, hypertrophy-independent, and improved by beta-blockade. Circ Res. 91:255-262.
Moeller MJ, Sanden SK, Soofi A, Wiggins RC, Holzman LB. 2002Two Gene Fragments that Direct Podocyte-Specific Expression in Transgenic Mice. J Am Soc Nephrol. 13:1561-1567.
Pendl GG, Robert C, Steinert M, Thanos R, Eytner R, Borges E, Wild MK, Lowe JB, Fuhlbrigge RC, Kupper TS, Vestweber D, Grabbe S. 2002Immature mouse dendritic cells enter inflamed tissue, a process that requires E- and P-selectin, but not P-selectin glycoprotein ligand 1. Blood. 99(3):946-56.
Peng L, Bhatia N, Parker AC, Zhu Y, Fay WP.2002Endogenous vitronectin and plasminogen activator inhibitor-1 promote neointima formation in murine carotid arteries. Arterioscler Thromb Vasc Biol. 22(6):934-9.
Raetzman LT, Ward R, Camper SA. 2002Lhx4 and Prop1 are required for cell survival and expansion of the pituitary primordia. Development. 129: 4229-4239.
Sheng H, Goich S, Wang A, Grachtchouk M, Lowe L, Mo R, Lin K, de Sauvage FJ, Sasaki H, Hui CC, Dlugosz AA. 2002Dissecting the oncogenic potential of Gli2: deletion of an NH(2)-terminal fragment alters skin tumor phenotype. Cancer Res. 62: 5308-16.
Smith PL, Myers JT, Rogers CE, Zhou L, Petryniak B, Becker DJ, Homeister JW, Lowe JB.2002Conditional control of selectin ligand expression and global fucosylation events in mice with a targeted mutation at the FX locus. J Cell Biol. 158:801-815.
Suh H. Gage PJ. Drouin J. Camper SA.2002Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification. Development – Supplement. 129:329-37.
Wishart MJ, Dixon JE. 2002The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production. Proc Natl Acad Sci U S A. 99:2112-2117.
Yu T, Thomas DM, Zhu W, Goodman M, Gumucio DL. 2002Regulation of fetal versus embryonic gamma globin genes: appropriate developmental stage expression patterns in the presence of HS2 of the locus control region. Blood. 99:1082-1084.
Zavros Y, Rieder G, Ferguson A, Samuelson LC, Merchant JL. 2002Hypergastrinemia in response to gastric inflammation suppresses somatostatin. Am J Physiol Gastrointest Liver Physiol. 282:G175-83.
Zavros Y, Rieder G, Ferguson A, Samuelson LC, Merchant JL. 2002Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice. Gastroenterology. 122:119-33.
Zhang K, Kurachi S, Kurachi K.2002Genetic mechanisms of age regulation of protein C and blood coagulation.  J Biol Chem. 277:4532-4540.
Brinkmeier ML, Stahl JH, Gordon DF, Ross BD, Sarapura VD, Dowding JM, Kendall SK, Lloyd RV, Ridgway EC, Camper SA. 2001Thyroid hormone-responsive pituitary hyperplasia independent of somatostatin receptor 2.Mol Endocrinol. 15:2129-2136.
Brown NL, Patel S, Brzezinski J, Glaser T. 2001Math5 is required for retinal ganglion cell and optic nerve formation.  Development. 128:2497-508.
Cushman LJ, Watkins-Chow DE, Brinkmeier ML, Raetzman LT, Radak AL, Lloyd RV, Camper SA. 2001Persistent Prop1 expression delays gonadotrope differentiation and enhances pituitary tumor susceptibility. Hum Mol Genet. 10:1141-53.
Domino SE, Zhang L, Gillespie PJ, Saunders TL, Lowe, JB.2001Deficiency of reproductive tract alpha(1,2)fucosylated glycans and normal fertility in mice with targeted deletions of the FUT1 or FUT2 alpha(1,2)fucosyltransferase locus. Molec. Cell. Biol. 21:8336-8345.
Franic TV, Judd LM, Robinson D, Barrett SP, Scarff KL, Gleeson PA, Samuelson LC, Van Driel IR. 2001Regulation of gastric epithelial cell development revealed in H(+)/K(+)-ATPase beta-subunit- and gastrin-deficient mice. Am J Physiol Gastrointest Liver Physiol. 281:G1502-11.
Homeister JW, Thall AD, Petryniak B, Maly P, Rogers CE, Smith PL, Kelly RJ, Gersten KM, Askari SW, Cheng G, Smithson G, Marks RM, Misra AK, Hindsgaul O, von Andrian UH, Lowe JB. 2001The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing. Immunity. 15:115-26.
Kearney JA. Plummer NW. Smith MR. Kapur J. Cummins TR. Waxman SG. Goldin AL. Meisler MH.2001A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities. Neuroscience. 102:307-17.
Lee J, Prohaska JR, Thiele DJ. 2001Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development. Proc Natl Acad Sci U S A. 98:6842-7.
Mears AJ, Kondo M, Swain PK, Takada Y, Bush RA, Saunders TL, Sieving PA, Swaroop A.2001Nrl is required for rod photoreceptor development. Nat Genet. 29:447-52.
Rao DS, Chang JC, Kumar PD, Mizukami I, Smithson GM, Bradley SV, Parlow AF, Ross TS. 2001Huntingtin Interacting Protein 1 Is a Clathrin Coat Binding Protein Required for Differentiation of late Spermatogenic  Progenitors.  Mol Cell Biol. 21(22):7796-806.
Scheuner D, Song B, McEwen E, Liu C, Laybutt R, Gillespie P, Saunders T, Bonner-Weir S, Kaufman RJ.2001Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell. 7:1165-76.
Seasholtz AF, Burrows HL, Karolyi IJ, Camper SA.2001Mouse models of altered CRH-binding protein expression. 22:743-51.
Smithson G, Rogers CE, Smith PL, Scheidegger EP, Petryniak B, Myers JT, Kim DS, Homeister JW, Lowe JB.2001Fuc-TVII is required for T helper 1 and T cytotoxic 1 lymphocyte selectin ligand expression and recruitment in inflammation, and together with Fuc-TIV regulates naive T cell trafficking to lymph nodes. J Exp Med. 194:601-14.
Sun D, Samuelson LC, Yang T, Huang Y, Paliege A, Saunders T, Briggs J, Schnermann J.2001Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors. Proc Natl Acad Sci U S A. 98:9983-8.
Zhao L. Bakke M. Krimkevich Y. Cushman LJ. Parlow AF. Camper SA. Parker KL.2001Steroidogenic factor 1 (SF1) is essential for pituitary gonadotrope function. Development. 128(2):147-54.
Zhao L, Bakke M, Krimkevich Y, Cushman LJ, Parlow AF, Camper SA, Parker KL.  2001Hypomorphic phenotype in mice with pituitary-specific knockout of steroidogenic factor 1. Genesis. 30(2):65-9.
Adams K. Ackerly H. Cunningham K. Dunnick W.2000A DNase I hypersensitive site near the murine gamma1 switch region contributes to insertion site independence of transgenes and modulates the amount of transcripts induced by CD40 ligation. International Immunology. 12(12):1705-13.
Ahmad A. Brinson M. Hodges BL. Chamberlain JS. Amalfitano A.2000Mdx mice inducibly expressing dystrophin provide insights into the potential of gene therapy for duchenne muscular dystrophy. Human Molecular Genetics. 9(17):2507-15.
Crawford GE. Faulkner JA. Crosbie RH. Campbell KP. Froehner SC. Chamberlain JS.2000Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain. Journal of Cell Biology. 150(6):1399-410.
Cui J. Eitzman DT. Westrick RJ. Christie PD. Xu ZJ. Yang AY. Purkayastha AA. Yang TL. Metz AL. Gallagher KP. Tyson JA. Rosenberg RD. Ginsburg D.2000Spontaneous thrombosis in mice carrying the factor V Leiden mutation. Blood. 96(13):4222-6.
Cushman LJ. Burrows HL. Seasholtz AF. Lewandoski M. Muzyczka N. Camper SA.2000Cre-mediated recombination in the pituitary gland. Genesis: the Journal of Genetics & Development. 28(3-4):167-74.
Disatnik MH. Chamberlain JS. Rando TA. 2000Dystrophin mutations predict cellular susceptibility to oxidative stress. Muscle & Nerve. 23(5):784-92.
Eitzman DT, Westrick RJ, Nabel EG, Ginsburg D. 2000Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice. Blood. 95:577-580.
Escayg A., De Waard, M., Lee, D.D., Bichet, D., Wolf, P., Mayer, T., Johnston, J., Baloh, R., Sander, T. and Meisler, M.H2000Coding and noncoding variation of the human calcium channel 4 subunit gene CACNB4 in patients with idiopathic generalized epilepsy and episodic ataxia. Am. J. Hum. Genet. 66:1531–1539.
Grachtchouk M, Mo R, Yu S, Zhang X, Sasaki H, Hui Cc, Dlugosz AA.2000Basal cell carcinomas in mice overexpressing Gli2 in skin. Nature Genetics 24:216-217.
Kurachi K, Kurachi S. 2000Genetic mechanisms of age regulation of blood coagulation: factor IX model.Arterioscler Thromb Vasc Biol. 20:902-906.
Kurachi K, Zhang K, Ameri A, Huo J, Atoda H, Kurachi S.2000Genetic and molecular mechanisms of age regulation (homeostasis) of blood coagulation. IUBMB Life. 49:189-96.
Lynch GS, Rafael JA, Chamberlain JS, Faulkner JA. 2000Contraction-induced injury to single permeabilized muscle fibers from mdx, transgenic mdx, and control mice.  Am J Physiol Cell Physiol. 279(4):C1290-4.
Moeller MJ, Kovari IA, Holzman LB.2000Evaluation of a new tool for exploring podocyte biology: mouse Nphs1 5′ flanking region drives LacZ expression in podocytes. J Am Soc Nephrol. 11(12):2306-14.
Post LC, Margulies EH, Kuo A, Innis JW.2000Severe limb defects in Hypodactyly mice result from the expression of a novel, mutant HOXA13 protein. Dev Biol 217:290-300.
Tanaka M, Yamasaki N, Izumo S. 2000Phenotypic characterization of the murine Nkx2.6 homeobox gene by gene targeting. Mol Cell Biol. 20:2874-9.
Wells AD. Li XC. Li Y. Walsh MC. Zheng XX. Wu Z. Nunez G. Tang A. Sayegh M. Hancock WW. Strom TB. Turka LA.2000Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance. Nature Medicine. 5(11):1303-7.
Weninger W, Ulfman LH, Cheng G, Souchkova N, Quackenbush EJ, Lowe JB, von Andrian UH.2000Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels.  Immunity. 12:665-676.
Wharram BL. Goyal M. Gillespie PJ. Wiggins JE. Kershaw DB. Holzman LB. Dysko RC. Saunders TL. Samuelson LC. Wiggins RC.2000Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate. Journal of Clinical Investigation. 106:1281-90.
Yang TL, Cui J, Taylor JM, Yang A, Gruber SB, Ginsburg D. 2000Rescue of fatal neonatal hemorrhage in factor V deficient mice by low level transgene expression. Thromb Haemost. 83:70-77.
Kurachi S, Deyashiki Y, Takeshita J, Kurachi K. 1999Genetic mechanisms of age regulation of human blood coagulation factor IX. Science. 285:739-743.
Beurskens FJ, Kuenen JD, Hofhuis F, Fluit AC, Robins DM, Van Dijk H. 1999Sex-limited protein: in vitro and in vivo functions. Clin Exp Immunol. 116(3):395-400.
Collins JT, Dunnick WA. 1999Cutting edge: IFN-gamma regulated germline transcripts are expressed from gamma2a transgenes independently of the heavy chain 3′ enhancers. J Immunol. 163:5758-5762.
Dougherty KM, Pearson JM, Yang AY, Westrick RJ, Baker MS, Ginsburg D. 1999The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival. Proc Natl Acad Sci U S A. 96:686-91.
Fay WP, Parker AC, Ansari MN, Zheng X, Ginsburg D. 1999Vitronectin inhibits the thrombotic response to arterial injury in mice. Blood. 93:1825-30.
Gage PJ, Suh H, Camper SA . 1999Dosage requirement of pitx2 for development of multiple organs. Development. 126:4643-4651.
Hinkle KL, Samuelson LC. 1999Lessons learned from gastrin gene deletion in mice. Am J Physiol 277:G500-G505.
Karolyi IJ, Burrows HL, Ramesh TM, Nakajima M, Lesh JS, Seong E, Camper SA, Seasholtz AF. 1999Altered anxiety and weight gain in corticotropin-releasing hormone-binding protein-deficient mice.Proc Natl Acad Sci U S A. 96(20):11595-11600.
Lacourse KA, Swanberg LJ, Gillespie PJ, Rehfeld JF, Saunders TL, Samuelson LC.1999Pancreatic function in CCK-deficient mice: adaptation to dietary protein does not require CCK. Am J Physiol. 276:G1302-309.
Lay JM, Gillespie PJ, Samuelson LC.1999Murine prenatal expression of cholecystokinin in neural crest, enteric neurons, and enteroendocrine cells. Developmental Dynamics. 216:290-200.
Lumeng CN, Hauser M, Brown V, Chamberlain JS. 1999Expression of the 71 kDa dystrophin isoform (Dp71) evaluated by gene targeting. Brain Res. 830:174-178.
Mohlke KL, Purkayastha AA, Westrick RJ, Smith PL, Petryniak B, Lowe JB, Ginsburg D.1999Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase. Cell 96:111-120.
Stahl JH, Kendall SK, Brinkmeier ML, Greco TL, Watkins-Chow DE, Campos-Barros A, Lloyd RV, Camper SA.1999Thyroid hormone is essential for pituitary somatotropes and lactotropes. Endocrinology. 140:1884-1892.
Tanaka M, Wechsler SB, Lee IW, Yamasaki N, Lawitts JA, Izumo S. 1999Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5. Development. 126(7):1439-1450.
Tanaka M, Chen Z, Bartunkova S, Yamasaki N, Izumo S.1999The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development. 126(6):1269-80.
Türkay A , Saunders TL, Kurachi K.1999Intrauterine gene transfer: gestational stage-specific gene delivery in mice. Gene Therapy. 6:1685-1694.
Xiao JH, Feng X, Di W, Peng ZH, Li LA, Chambon P, Voorhees JJ.1999Identification of heparin-binding EGF-like growth factor as a target in intercellular regulation of epidermal basal cell growth by suprabasal retinoic acid receptors. EMBO J 18:1539-48.
Wells AD, Li XC, Li Y, Walsh MC, Zheng XX, Wu Z, Nunez G, Tang A, Sayegh M, Hancock WW, Strom TB, Turka LA. 1999Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance. Nat Med. 5:1303-7.
Zhu W, TomHon C, Mason M, Campbell T, Shelden E, Richards N, Goodman M, Gumucio DL.1999Analysis of linked human epsilon and gamma transgenes: effect of locus control region hypersensitive sites 2 and 3 or a distal YY1 mutation on stage-specific expression patterns. Blood. 93:3540-3549.
Brinkmeier ML, Gordon DF, Dowding JM, Saunders TL, Kendall SK, Sarapura VD, Wood WM, Ridgway EC, Camper SA.1998Cell-specific expression of the mouse glycoprotein hormone alpha-subunit gene requires multiple interacting DNA elements in transgenic mice and cultured cells. Mol Endocrinol. 12:622-33.
Burrows HL, Nakajima M, Lesh JS, Goosens KA, Samuelson LC, Inui A, Camper SA, Seasholtz AF. 1998Excess corticotropin releasing hormone-binding protein in the hypothalamic-pituitary-adrenal axis in transgenic mice. J. Clin. Invest. 101:1439-447.
Cunningham K, Ackerly H, Alt F, Dunnick W. 1998Potential regulatory elements for germline transcription in or near murine Sgamma1.Int Immunol. 10:527-536.
Cunningham K, Ackerly H, Claflin L, Collins J, Wu P, Ford C, Lansford R, Alt F, Dunnick WA.1998Germline transcription and recombination of a murine VDJmudeltagamma1 transgene. Int Immunol. 10:1027-1037.
Friis-Hansen, L, Sundler, F, Li, Y, Gillespie, PJ, Saunders, TL, Greenson, JK, Owyang, C, Rehfeld, JF, Samuelson, LC. 1998Impaired Gastric Acid Secretion in Gastrin-Deficient Mice. Am. J. Physiol. 274:G561-G568.
Kulig E, Camper SA, Kuecker S, Jin L, Lloyd RV. 1998Remodeling of Hyperplastic Pituitaries in Hypothyroid us-Subunit Knockout Mice After Thyroxine and 1713-Estradiol Treatment: Role of Apoptosis. Endocr Pathol. 9:261-274.
Lay JM, Friis-Hansen L, Gillespie PJ, Samuelson LC. 1998Rapid confirmation of gene targeting in embryonic stem cells using two long-range PCR techniques.Transgenic Res. 7:135-140.
Petschner, F, Zimmermann, C, Strasser, A, Grillot, D, Nunez, G, Pircher, H. 1998Constitutive expression of Bcl-x(L) or Bcl-2 prevents peptide antigen-induced T cell deletion but does not influence T cell homeostasis after a viral infection. Eur. J. Immunol. 28:560-569.
Pinson, KI, Dunbar, L, Samuelson, L, Gumucio, DL. 1998Targeted disruption of the mouse villin gene does not impair the morphogenesis of microvilli. Dev. Dyn. 211:109-121.
Probst FJ, Fridell RA, Raphael y, Saunders TL, Wang A, Liang Y, Morell RJ, Touchman JW, Lyons RH, Noben-Trauth K, Friedman TB, Camper SA. 1998Correction of Deafness in shaker-2 Mice by an Unconventional Myosin in a BAC Transgene.Science. 280:1444-1447.
WangA, Liang Y, Fridell RA, Probst FJ, Wilcox ER, Touchman JW, MortonCC, Morell RJ, Noben-Trauth K, Camper SA, Friedman TB. 1998Association of Unconventional Myosin MYO15 Mutations with Human Nonsyndromic Deafness DFNB3. Science. 280:1447 – 1451.
Solvason, N, Wu, WW, Kabra, N, Lund-Johansen, F, Roncarolo, MG, Behrens, TW, Grillot, DAM, Nunez, G, Lees, E, Howard, M. 1998Transgene expression of bcl-x(L) permits anti-immunoglobulin (Ig)-induced proliferation in xid B cells J. Exp. Med. 187: 1081-1091.
Wu P, Claflin L. 1998Promoter-associated displacement of hypermutations.Int Immunol. 10:1131-1138.
Yu RN, Ito M, Saunders TL, Camper SA, Jameson JL. 1998Role of Ahch in gonadal development and gametogenesis. Nat Genet 20:353-7.
Chamberlain, JS.1997Dystrophin levels required for genetic correction of Duchenne muscular dystrophy. Bas. Appl. Myol. 7:251-255.
Chamberlain, JS, Corrado, K, Rafael ,JA, Cox, GA, Hauser, M, Lumeng, C. 1997Interactions between dystrophin and the sarcolemma membrane. Soc Gen Physiol Ser 52:19-29.
Elenich, LA, Ford, CS, Collins, JT, Dunnick, WA. 1997gamma1 Heavy Chain Transgenes are Responsive to IFN-gamma Repression and CD40 Ligation. J. Immunol. 158:4564-4573.
Feng, X, Peng, ZH, Di, W, Li, XY, Rochette-Egly, C, Chambon, P, Voorhees, JJ, Xiao JH. 1997Suprabasal expression of a dominant-negative RXR alpha mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids. Genes Dev. 11:59-71.
Lowe JB.1997Selectin ligands, leukocyte trafficking, and fucosyltransferase genes. Kidney Int. 51:1418-1426.
Lynch, GS, Rafael, JA, Hinkle, RT, Cole, NM, Chamberlain, JS, Faulkner, JA. 1997Contractile properties of diaphragm muscle segments from old mdx and old transgenic mdx mice. Am. J. Phys-Cell Phys. 41:C2063-C2068.
Nelson, SA, Robins, DM. 1997Regulatory capacity of an androgen-specific enhancer of the mouse Slp gene in transgenic mice. Mol. Cell. Endo. 133:89-97.
Ohnishi, H, Samuelson, LC, Yule, DI, Ernst, SA, Williams, JA. 1997Overexpression of Rab3D enhances regulated amylase secretion from pancreatic acini of transgenic mice J Clin. Inv. 100:3044-3052.
Straub, V, Rafael, JA, Chamberlain, JS, Campbell, KP. 1997Animal models for muscular dystrophy show different patterns of sarcolemmal disruption. J. Cell. Biol. 139:375-385.
TomHon, C, Zhu, W, Millinoff, D, Hayasaka, K, Slightom, JL, Goodman, M, Gumucio, DL.1997Evolution of a fetal expression pattern via cis changes near the gamma globin gene. J. Biol. Chem. 272:14062-14066.
Burrows, HL, Birkmeier, TS, Seasholtz, AF, Camper, SA. 1996Targeted Ablation of Cells in the Pituitary Primordia of Transgenic Mice. Mol. Endo. 10:1467-1477.
Corrado, K, Rafael, JA, Mills, PL, Cole, NM, Faulkner, JA, Wang, K, Chamberlain, JS. 1996Transgenic mdx Mice Expressing Dystrophin with a Deletion in the Actin-Binding Domain Display a “Mild Becker” Phenotype. J. Cell Biology. 134:873-884.
Cui, J, O’Shea KS, Purkayastha A, Saunders TL, Ginsburg, D. 1996Fatal Haemorrhage and Incomplete Block to Embryogenesis in Mice Lacking Coagulation Factor V. Nature. 382:66-68.
Eitzman, DT, Krauss, JC, Shen, T, Cui, J, Ginsburg, D.1996Lack of plasminogen activator inhibitor-1 effect in a transgenic mouse model of metastatic melanoma. Blood. 87:4718-4722.
Eitzman, DT, McCoy, RD, Zheng, X, Fay, WP, Shen, T, Ginsburg, D, Simon, RH. 1996Bleomycin-Induced Pulmonary Fibrosis in Transgenic Mice that Either Lack or Overexpress the Murine Plasminogen Activator Inhibitor-1 Gene. J. Clin. Invest. 97:232-237.
Elenich, LA, Ford, CS, Dunnick, WA.1996The gamma 1 Heavy Chain Gene Includes all of the cis-Acting Elements Necessary for Expression of Properly Regulated Germ-Line Transcripts. J. Immunol. 157:176-182.
Grillot, DA, Merino, R, Pena, JC, Fanslow, WC, Finkelman, FD, Thompson, CB, Nunez, G. 1996bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice. J. Exp. Med. 183:381-391.
Maly P, Thall AD, Petryniak B, Rogers CE, Smith PL, Marks RM, Kelly RJ, Gersten KM, Cheng G, Saunders TL, Camper SA, Camphausen RT, Sullivan RX, Isogai Y, Hindsgaul O, von Andrian UH, Lowe JB.1996The alpha(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis. Cell. 86:643-653.
Rafael, JA, Cox, GA, Corrado, K, Jung, D, Campbell, KP, Chamberlain, JS. 1996Forced expression of dystrophin deletion constructs reveals structure-function correlations. J .Cell Biol. 134:93-102.
Samuelson, LC. 1996Transgenic approaches to salivary gland research. Ann. Rev. Phys. 58: 209-229.
Thall, AD, Murphy, HS, Lowe, JB. 1996alpha 1,3-Galactosyltransferase-deficient mice produce naturally occurring cytotoxic anti-Gal antibodies.Transplant. Proc. 28:556-557.
Tucker RM, Burke DT. 1996Transgenic mice for the establishment of histidinol-resistant embryonic fibroblast feeder layers.FASEB J. 10:1641-1645.
Camper, SA, Saunders, TL, Kendall, SK, Keri, RA, Seasholtz, AF, Gordon, DF, Birkmeier, TS, Keegan, CE, Karolyi, IJ, Roller, ML, Burrows, HL, Samuelson, LC. 1995Implementing transgenic and embryonic stem cell technology to study gene expression, cell-cell interactions and gene function. Biol. Reprod. 52:246-2457.
Chen C, Nagy Z, Radic MZ, Hardy RR, Huszar D, Camper SA, Weigert M. 1995The site and stage of anti-DNA B-cell deletion. Nature. 373:252-255.
Dunnick W Elenich L Cunningham K Chrisp C Claflin L.1995Tumorigenesis in mice with an SV40 T antigen transgene driven by the immunoglobulin gamma 1 heavy chain germline promoter. Curr. Top. Microbiol. Immunol. 194:163-169.
Grillot, DA, Merino, R, Nunez, G. 1995Bcl-XL Displays Restricted Distribution During T Cell Development and Inhibits Multiple Forms of Apoptosis but not Clonal Deletion in Transgenic Mice. J. Exp. Med. 182:1973-1983.
Kendall, SK, Samuelson, LC, Saunders, TL, Wood, RI, Camper, SA. 1995Targeted Disruption of the Pituitary Glycoprotein Hormone alpha-subunit Produces Hypogonadal and Hypothyroid Mice. Genes Dev. 9:2007-2019.
Phelps SF, Hauser MA, Cole NM, Rafael JA, Hinkle RT, Faulkner JA, Chamberlain JS. 1995Expression of full-length and truncated dystrophin mini-genes in transgenic mdx mice. Human Mol. Genet. 4:1251-1258.
Radic, MZ, Ibrahim, SM, Rauch, J, Camper, SA, Weigert, M. 1995Constitutive secretion of transgene-encoded IgG2b autoantibodies leads to symptoms of autoimmune disease. J. Immunol. 155:3213-3222.
Thall, AD, Maly, P, Lowe, JB. 1995Oocyte Gal-alpha1,3Gal Epitopes Implicated in Sperm Adhesion to the Zona Pellucida Glycoprotein ZP3 are not Required for Fertilization in the Mouse. J. Biol. Chem. 270:21437-21440.
Zheng, XX, Saunders, TL, Samuelson, LC, Camper, SA, Ginsburg, D. 1995Vitronectin is not Essential for Mammalian Development. Proc. Natl. Acad. Sci. U.S.A. 92:12326-12430.
Chen C, Radic MZ, Erikson J, Camper SA, Litwin S, Hardy RR, Weigert M, 1994Deletion and editing of B cells that express antibodies to DNA. J. Immunol. 152:1970-1982.
Chen EH, Mitchell BS. 1994Hereditary overexpression of adenosine deaminase in erythrocytes: studies in erythroid cell lines and transgenic mice. Blood. 84:2346-2353.
Denetclaw WF, Jr Hopf FW, Cox GA, Chamberlain JS, Steinhardt RA. 1994Myotubes from transgenic mdx mice expressing full-length dystrophin show normal calcium regulation. Mol. Biol. Cell. 5:1159-1167.
Cox GA, Sunada Y, Campbell KP, Chamberlain JS.1994Dp71 can restore the dystrophin-associated glycoprotein complex in muscle but fails to prevent dystrophy. Nat. Genet. 8:333-339.
Keegan, CE, Karolyi, IJ, Knapp, LT, Bourbonais, FJ, Camper, SA, Seasholtz, AF. 1994Expression of corticotropin-releasing hormone transgenes in neurons of adult and developing mice. Mol. Cell. Neurosci. 5:505-514.
Keri RA, Wolfe MW, Saunders TL, Anderson I Kendall SK Wagner T, Yeung J, Gorski J, Nett TM, Camper SA, Nilson, JH. 1994The proximal promoter of the bovine luteinizing hormone beta-subunit gene confers gonadotrope-specific expression and regulation by gonadotropin-releasing hormone, testosterone, and 17 beta-estradiol in transgenic mice. Mol. Endocrinol. 8:1807-1816.
Kendall SK, Gordon DF, Birkmeier TS, Petrey D, Sarapura VD, O’Shea KS, Wood WM, Lloyd RV, Ridgway EC, Camper SA.1994Enhancer-mediated high level expression of mouse pituitary glycoprotein hormone alpha-subunit transgene in thyrotropes, gonadotropes, and developing pituitary gland. Mol. Endocrinol. 8:1420-1433.
Rafael JA, Sunada Y, Cole NM, Campbell KP, Faulkner JA, Chamberlain JS. 1994Prevention of dystrophic pathology in mdx mice by a truncated dystrophin isoform. Hum. Mol. Genet. 3:1725-1733.
Cox GA, Cole NM, Matsumura K, Phelps SF, Hauschka, SD Campbell KP, Faulkner JA, Chamberlain JS.1993Overexpression of dystrophin in transgenic mdx mice eliminates dystrophic symptoms without toxicity. Nature 364:725-729.
Gay, D, Saunders, T, Camper, S, Weigert, M. 1993Receptor editing: an approach by autoreactive B cells to escape tolerance. J. Exp. Med. 177:999-1008.
Shlomchik, MJ, Zharhary, D, Saunders, T, Camper, SA, Weigert, MG.1993A rheumatoid factor transgenic mouse model of autoantibody regulation. Int. Immunol. 5:1329-1341.
Dunnick, W, Elenich, L, Berry, J, Albrecht, D, Stavnezer, J, Claflin, JL. 1992Regulation of switch recombination to the murine gamma 1 gene. Curr. Top. Microbiol. Immunol. 182:143-147.
Ting CN, Rosenberg MP, Snow CM, Samuelson LC, Meisler MH. 1992Endogenous retroviral sequences are required for tissue-specific expression of a human salivary amylase gene. Genes Dev. 6:1457-1465.
Carmack CE, Camper SA, Mackle JJ, Gerhard WU, Weigert MG.1991Influence of a V kappa 8 L chain transgene on endogenous rearrangements and the immune response to the HA(Sb) determinant on influenza virus. J. Immunol. 147:2024-2033.
Erikson J Radic MZ Camper SA Hardy RR Carmack C Weigert M.1991Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice. Nature. 349:331-334.
Kendall SK, Saunders TL, Jin L, Lloyd RV, Glode LM, Nett TM, Keri RA, Nilson JH, Camper SA. 1991Targeted ablation of pituitary gonadotropes in transgenic mice. Mol. Endocrinol. 5:2025-2036.