Publications Supported by the Transgenic Core

AuthorsYearPublication
Matsushita Y, Liu J, Chu AKY, Tsutsumi-Arai C, Nagata M, Arai Y, Ono W, Yamamoto K, Saunders TL, Welch JD, Ono N.2023Bone marrow endosteal stem cells dictate active osteogenesis and aggressive tumorigenesis. Matsushita Y, Liu J, Chu AKY, Tsutsumi-Arai C, Nagata M, Arai Y, Ono W, Yamamoto K, Saunders TL, Welch JD, Ono N. Nat Commun. 2023 Apr 25;14(1):2383. doi: 10.1038/s41467-023-38034-2. PMID: 37185464 PubMed: https://pubmed.ncbi.nlm.nih.gov/37185464/
Quan T, Xia W, He T, Calderone K, Bou-Gharios G, Voorhees JJ, Dlugosz AA, Fisher GJ.2023Matrix Metalloproteinase-1 Expression in Fibroblasts Accelerates Dermal Aging and Promotes Papilloma Development in Mouse Skin. Quan T, Xia W, He T, Calderone K, Bou-Gharios G, Voorhees JJ, Dlugosz AA, Fisher GJ. J Invest Dermatol. 2023 Mar 11:S0022-202X(23)01827-4. doi: 10.1016/j.jid.2023.02.028. Online ahead of print. PMID: 36914001
Lartey NL, van der Ent M, Alonzo R, Chen D, King PD.2023A temporally-restricted pattern of endothelial cell collagen 4 alpha 1 expression during embryonic development determined with a novel knockin Col4a1-P2A-eGFP mouse line. Genesis. 2023 Jul 27:e23539. doi: 10.1002/dvg.23539. Online ahead of print. PMID: 37501352
TL Saunders (ed).2023Transgenesis. 2023. Springer-Nature, Humana, New York NY.
Vohnoutka RB, Kuppa A, Hegde Y, Chen Y, Pant A, Tohme ME, Choi EK, McCarty SM, Bagchi DP, Du X, Chen Y, Chen VL, Mori H, Bielak LF, Maguire LH, Handelman SK, Sexton JZ, Saunders TL, Halligan BD, Speliotes EK.2023Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity. J Mol Endocrinol. 2023 Mar 10;70(3):e220131. doi: 10.1530/JME-22-0131.
PMID: 36748836
Bossert JM, Mejias-Aponte CA, Saunders T, Altidor L, Emery M, Fredriksson I, Batista A, Claypool SM, Caldwell KE, Reiner DJ, Chow JJ, Foltz M, Kumar V, Seasholtz A, Hughes E, Filipiak W, Harvey BK, Richie CT, Vautier F, Gomez JL, Michaelides M, Kieffer BL, Watson SJ, Akil H, Shaham Y.2023Effect of selective lesions of nucleus accumbens µ-opioid receptor-expressing cells on heroin self-administration in male and female rats: a study with novel Oprm1-Cre knock-in rats. J Neurosci. 2023 Jan 30:JN-RM-2049-22. doi: 10.1523/JNEUROSCI.2049-22.2023. Online ahead of print. PMID: 36717230 URL: https://pubmed.ncbi.nlm.nih.gov/36717230/
Dumrongprechachan V, Salisbury RB, Butler L, MacDonald ML, Kozorovitskiy Y.2022Dynamic proteomic and phosphoproteomic atlas of corticostriatal axons in neurodevelopment. Dumrongprechachan V, Salisbury RB, Butler L, MacDonald ML, Kozorovitskiy Y. Elife. 2022 Oct 14;11:e78847. doi: 10.7554/eLife.78847. PMID: 36239373
Vohnoutka R, Kuppa, A, Hegde Y, Chen Y, Pant A, Tohme M, Choi EY, McCarty S, Bagchi D, Du X, Chen Y, Chen V, Mori H, Bielak L, Maguire L, Handelman S, Sexton J, Saunders T, Halligan B, Speliotes E.2022Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity. J Mol Endocrin. DOI: https://doi.org/10.1530/JME-22-0131 URL: https://jme.bioscientifica.com/view/journals/jme/aop/jme-22-0131/jme-22-0131.xml
VanDenBerg KR, Oravecz-Wilson K, Krolikowski L, Hill V, Reddy P, Freeman ZT.2022Impact of Automated Genotyping and Increased Breeding Oversight on Overall Mouse Breeding Colony Productivity. Front Physiol. 2022 Jul 18;13:925784. doi: 10.3389/fphys.2022.925784. eCollection 2022.
PMID: 35923239
Verhaegen ME, Harms PW, Van Goor JJ, Arche J, Patrick MT, Wilbert D, Zabawa H, Grachtchouk M, Liu CJ, Hu K, Kelly MC, Chen P, Saunders TL, Weidinger S, Syu LJ, Runge JS, Gudjonsson JE, Wong SY, Brownell I, Cieslik M, Udager AM, Chinnaiyan AM, Tsoi LC, Dlugosz AA.2022Direct cellular reprogramming enables development of viral T antigen-driven Merkel cell carcinoma in mice. J Clin Invest. 2022 Feb 10:e152069. doi: 10.1172/JCI152069. Online ahead of print. PMID: 35143422
Zhu X, Leboeuf M, Liu F, Grachtchouk M, Seykora JT, Morrisey EE, Dlugosz AA, Millar SE.2022HDAC1/2 Control Proliferation and Survival in Adult Epidermis and Pre_Basal Cell Carcinoma through p16 and p53. J Invest Dermatol. 2022 Jan;142(1):77-87.e10. doi: 10.1016/j.jid.2021.05.026. Epub 2021 Jul 18. PMID: 34284046
Chen D, Hughes ED, Saunders TL, Wu J, Hern‡ndez V‡squez MN, Makinen T, King PD.2022Angiogenesis depends upon EPHB4-mediated export of collagen IV from vascular endothelial cells. JCI Insight. 2022 Jan 11:e156928. doi: 10.1172/jci.insight.156928. Online ahead of print. PMID: 35015735
Mohamed FF, Ge C, Cowling RT, Lucas D, Hallett SA, Ono N, Binrayes AA, Greenberg B, Franceschi RT.2022Bone Res. 2022 Feb 9;10(1):11. doi: 10.1038/s41413-021-00182-w. PMID: 35140200
Marinelli I, Parekh VS, Fletcher PA, Thompson B, Ren J, Tang X, Saunders TL, Ha J, Sherman A, Bertram R, Satin LS.2022Slow oscillations persist in pancreatic beta cells lacking phosphofructokinase M. Biophys J. 2022 Feb 4:S0006-3495(22)00077-7. doi: 10.1016/j.bpj.2022.01.027. Online ahead of print. PMID: 35131294
Chen D, Hughes ED, Saunders TL, Wu J, Hern‡ndez V‡squez MN, Makinen T, King PD.2022JCI Insight. 2022 Jan 11:e156928. doi: 10.1172/jci.insight.156928. Online ahead of print. PMID: 35015735
Gregory LC, Gergics P, Nakaguma M, Bando H, Patti G, McCabe MJ, Fang Q, Ma Q, Ozel AB, Li JZ, Poina MM, Jorge AAL, Benedetti AFF, Lerario AM, Arnhold IJP, Mendonca BB, Maghnie M, Camper SA, Carvalho LRS, Dattani MT.2021The phenotypic spectrum associated with OTX2 mutations in humans. Eur J Endocrinol. 2021 May 25;185(1):121-135. doi: 10.1530/EJE-20-1453. PMID: 33950863
Daly AZ, Mortensen AH, Bando H, Camper SA.2021Pituitary Tumors and Immortalized Cell Lines Generated by Cre-Inducible Expression of SV40 T Antigen. Endocrinology. 2021 Jul 1;162(7):bqab073. doi: 10.1210/endocr/bqab073. PMID: 33837405
Gualtieri A, Kyprianou N, Gregory LC, Vignola ML, Nicholson JG, Tan R, Inoue SI, Scagliotti V, Casado P, Blackburn J, Abollo-Jimenez F, Marinelli E, Besser REJ, Hšgler W, Karen Temple I, Davies JH, Gagunashvili A, Robinson ICAF, Camper SA, Davis SW, Cutillas PR, Gevers EF, Aoki Y, Dattani MT, Gaston-Massuet C.2021Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans. Nat Commun. 2021 Apr 1;12(1):2028. doi: 10.1038/s41467-021-21712-4. PMID: 33795686
Daly AZ, Dudley LA, Peel MT, Liebhaber SA, Parker SCJ, Camper SA.2021Multi-omic profiling of pituitary thyrotropic cells and progenitors. BMC Biol. 2021 Apr 15;19(1):76. doi: 10.1186/s12915-021-01009-0. PMID: 33858413
Nair TS, Kakaraparthi BN, Yang L, Lu L, Thomas TB, Morris AC, Kommareddi P, Kanicki A, Carey TE. 2021Slc44a2 deletion alters tetraspanin and N-cadherin expression: Reduced adhesion and enhanced proliferation in cultured mesenchymal lung cells. Tissue Cell. 2021 Dec;73:101599. doi: 10.1016/j.tice.2021.101599. Epub 2021 Jul 26. PMID: 34371293
Chen L, Zhai Y, Wang Y, Fearon ER, Nœ–ez G, Inohara N, Cho KR.2021Altering the Microbiome Inhibits Tumorigenesis in a Mouse Model of Oviductal High-Grade Serous Carcinoma. Cancer Res. 2021 Jun 15;81(12):3309-3318. doi: 10.1158/0008-5472.CAN-21-0106. Epub 2021 Apr 16. PMID: 33863776
Morinaga H, Mohri Y, Grachtchouk M, Asakawa K, Matsumura H, Oshima M, Takayama N, Kato T, Nishimori Y, Sorimachi Y, Takubo K, Suganami T, Iwama A, Iwakura Y, Dlugosz AA, Nishimura EK.2021Obesity accelerates hair thinning by stem cell-centric converging mechanisms. Nature. 2021 Jul;595(7866):266-271. doi: 10.1038/s41586-021-03624-x. Epub 2021 Jun 23. PMID: 34163066
Grachtchouk M, Liu J, Hutchin ME, Harms PW, Thomas D, Wei L, Wang A, Cummings D, Lowe L, Garlick J, Sciubba J, Chinnaiyan AM, Verhaegen ME, Dlugosz AA. 2021Constitutive Hedgehog/GLI2 signaling drives extracutaneous basaloid squamous cell carcinoma development and bone remodeling. Carcinogenesis. 2021 Aug 19;42(8):1100-1109. doi: 10.1093/carcin/bgab050. PMID: 34117865
Grunberg N, Pevsner-Fischer M, Goshen-Lago T, Diment J, Stein Y, Lavon H, Mayer S, Levi-Galibov O, Friedman G, Ofir-Birin Y, Syu LJ, Migliore C, Shimoni E, Stemmer SM, Brenner B, Dlugosz AA, Lyden D, Regev-Rudzki N, Ben-Aharon I, Scherz-Shouval R.2021Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1-Mediated Secretion of Extracellular Vesicles. Cancer Res. 2021 Apr 1;81(7):1639-1653. doi: 10.1158/0008-5472.CAN-20-2756. Epub 2021 Feb 5. PMID: 33547159
Quan T, Xiang Y, Liu Y, Qin Z, Yang Y, Bou-Gharios G, Voorhees JJ, Dlugosz AA, Fisher GJ.2021Dermal Fibroblast CCN1 Expression in Mice Recapitulates Human Skin Dermal Aging. J Invest Dermatol. 2021 Apr;141(4S):1007-1016. doi: 10.1016/j.jid.2020.07.019. Epub 2020 Aug 13. PMID: 32800875
Bosze B, Suarez-Navarro J, Soofi A, Lauderdale JD, Dressler GR, Brown NL. 2021Multiple roles for Pax2 in the embryonic mouse eye. Dev Biol. 2021 Apr;472:18-29. doi: 10.1016/j.ydbio.2020.12.020. Epub 2021 Jan 9. PMID: 33428890
Adams EJ, Khoriaty R, Kiseleva A, Cleuren ACA, Tomberg K, van der Ent MA, Gergics P, Tang VT, Zhu G, Hoenerhoff MJ, O'Shea KS, Saunders TL, Ginsburg D.2021Murine SEC24D can substitute functionally for SEC24C during embryonic development. Sci Rep. 2021 Oct 26;11(1):21100. doi: 10.1038/s41598-021-00579-x. PMID: 34702932
Kim S, Khoriaty R, Li L, McClune M, Kalfa TA, Wu J, Peltier D, Fujiwara H, Sun Y, Oravecz-Wilson K, King RA, Ginsburg D, Reddy P.2021ER-to-Golgi transport and SEC23-dependent COPII vesicles regulate T cell alloimmunity. J Clin Invest. 2021 Jan 19;131(2):e136574. doi: 10.1172/JCI136574. PMID: 33463537
Graniel JV, Bisht K, Friedman A, White J, Perkey E, Vanderbeck A, Moroz A, Carrington LJ, Brandstadter JD, Allen F, Shami AN, Thomas P, Crayton A, Manzor M, Mychalowych A, Chase J, Hammoud SS, Keegan CE, Maillard I, Nandakumar J.2021Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline. Life Sci Alliance. 2021 Oct 13;5(1):e202101208. doi: 10.26508/lsa.202101208. Print 2022 Jan. PMID: 34645668
Yu L, Myers G, Ku CJ, Schneider E, Wang Y, Singh SA, Jearawiriyapaisarn N, White A, Moriguchi T, Khoriaty R, Yamamoto M, Rosenfeld MG, Pedron J, Bushweller JH, Lim KC, Engel JD.2021An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation. Blood. 2021 Nov 4;138(18):1691-1704. doi: 10.1182/blood.2021011682. PMID: 34324630
Cote JL, Argetsinger LS, Flores A, Rupp AC, Cline JM, DeSantis LC, Bedard AH, Bagchi DP, Vander PB, Cacciaglia AM, Clutter ES, Chandrashekar G, MacDougald OA, Myers MG Jr, Carter-Su C.2021Deletion of the Brain-Specific alpha and delta Isoforms of Adapter Protein SH2B1 Protects Mice From Obesity. Diabetes. 2021 Feb;70(2):400-414. doi: 10.2337/db20-0687. Epub 2020 Nov 19. PMID: 33214137
Balendran V, Skidmore JM, Ritter KE, Gao J, Cimerman J, Beyer LA, Hurd EA, Raphael Y, Martin DM.2021Chromatin remodeler CHD7 is critical for cochlear morphogenesis and neurosensory patterning. Dev Biol. 2021 Sep;477:11-21. doi: 10.1016/j.ydbio.2021.05.009. Epub 2021 May 15. PMID: 34004180
Hallett SA, Matsushita Y, Ono W, Sakagami N, Mizuhashi K, Tokavanich N, Nagata M, Zhou A, Hirai T, Kronenberg HM, Ono N.2021Chondrocytes in the resting zone of the growth plate are maintained in a Wnt-inhibitory environment. Elife. 2021 Jul 26;10:e64513. doi: 10.7554/eLife.64513. PMID: 34309509
King R, Lin Z, Balbin-Cuesta G, Myers G, Friedman A, Zhu G, McGee B, Saunders TL, Kurita R, Nakamura Y, Engel JD, Reddy P, Khoriaty R.2021SEC23A rescues SEC23B-deficient congenital dyserythropoietic anemia type II. Sci Adv. 2021 Nov 26;7(48):eabj5293. doi: 10.1126/sciadv.abj5293. Epub 2021 Nov 24. PMID: 34818036
Fujiwara H, Seike K, Brooks MD, Mathew AV, Kovalenko I, Pal A, Lee HJ, Peltier D, Kim S, Liu C, Oravecz-Wilson K, Li L, Sun Y, Byun J, Maeda Y, Wicha MS, Saunders TL, Rehemtulla A, Lyssiotis CA, Pennathur S, Reddy P.2021Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology. Nat Immunol. 2021 Nov;22(11):1440-1451. doi: 10.1038/s41590-021-01048-3. Epub 2021 Oct 22. PMID: 34686860
Liang T, Hu Y, Zhang H, Xu Q, Smith CE, Zhang C, Kim JW, Wang SK, Saunders TL, Lu Y, Hu JC, Simmer JP.2021Mouse Dspp frameshift model of human dentinogenesis imperfecta. Sci Rep. 2021 Oct 19;11(1):20653. doi: 10.1038/s41598-021-00219-4. PMID: 34667213
Lim D, Wu KC, Lee A, Saunders TL, Ritchie HH.2021DSPP dosage affects tooth development and dentin mineralization. PLoS One. 2021 May 26;16(5):e0250429. doi: 10.1371/journal.pone.0250429. eCollection 2021. PMID: 34038418
Liang T, Hu Y, Kawasaki K, Zhang H, Zhang C, Saunders TL, Simmer JP, Hu JC.2021Odontogenesis-associated phosphoprotein truncation blocks ameloblast transition into maturation in OdaphC41*/C41* mice. Sci Rep. 2021 Jan 13;11(1):1132. doi: 10.1038/s41598-020-80912-y. PMID: 33441959
Graniel JV, Bisht K, Friedman A, White J, Perkey E, Vanderbeck A, Moroz A, Carrington LJ, Brandstadter JD, Allen F, Shami AN, Thomas P, Crayton A, Manzor M, Mychalowych A, Chase J, Hammoud SS, Keegan CE, Maillard I, Nandakumar J.J Clin Invest.J Clin Invest.2021Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline. Life Sci Alliance. 2021 Oct 13;5(1):e202101208. doi: 10.26508/lsa.202101208. Print 2022 Jan.

https://pubmed.ncbi.nlm.nih.gov/34546975
Braeuer RR, Walker NM, Misumi K, Mazzoni-Putman S, Aoki Y, Liao R, Vittal R, Kleer GG, Wheeler DS, Sexton JZ, Farver CF, Welch JD, Lama VN.
J Clin Invest.		2021Transcription factor FOXF1 identifies compartmentally distinct mesenchymal cells with a role in lung allograft fibrogenesis. 2021 Sep 21:e147343. doi: 10.1172/JCI147343. Online ahead of print. PMID: 34546975

https://pubmed.ncbi.nlm.nih.gov/34546975
Daly AZ, Mortensen AH, Bando H, Camper SA.2021Pituitary Tumors and Immortalized Cell Lines Generated by Cre-Inducible Expression of SV40 T Antigen. Endocrinology. 2021 Jul 1;162(7):bqab073. doi: 10.1210/endocr/bqab073.PMID: 33837405

https://pubmed.ncbi.nlm.nih.gov/33837405/
Bouza AA, Edokobi N, Hodges SL, Pinsky AM, Offord J, Piao L, Zhao YT, Lopatin AN, Lopez-Santiago LF, Isom LL.2021Sodium channel β1 subunits participate in regulated intramembrane proteolysis-excitation coupling. JCI Insight. 2021 Feb 8;6(3):141776. doi: 10.1172/jci.insight.141776. PMID: 33411695
Mohamed FF, Ge C, Binrayes A, Franceschi RT. J Dent Res.2020The Role of Discoidin Domain Receptor 2 in Tooth Development. 99(2):214-222. doi: 10.1177/0022034519892563. Epub 2019 Dec 23. PMID: 31869264
Cara AL, Myers MG, Elias CF.2020Lack of AR in LepRb Cells Disrupts Ambulatory Activity and Neuroendocrine Axes in a Sex-Specific Manner in Mice. Endocrinology. 2020 Aug 1;161(8):bqaa110. doi: 10.1210/endocr/bqaa110. PMID: 32609838
Cheng W, Ndoka E, Hutch C, Roelofs K, MacKinnon A, Khoury B, Magrisso J, Kim KS, Rhodes CJ, Olson DP, Seeley RJ, Sandoval D, Myers MG Jr.2020Leptin receptor-expressing nucleus tractus solitarius neurons suppress food intake independently of GLP1 in mice. JCI Insight. 2020 Apr 9;5(7):e134359. doi: 10.1172/jci.insight.134359. PMID: 32182221
Flak JN, Goforth PB, Dell'Orco J, Sabatini PV, Li C, Bozadjieva N, Sorensen M, Valenta A, Rupp A, Affinati AH, Cras-Méneur C, Ansari A, Sacksner J, Kodur N, Sandoval DA, Kennedy RT, Olson DP, Myers MG Jr.2020Ventromedial hypothalamic nucleus neuronal subset regulates blood glucose independently of insulin. J Clin Invest. 2020 Jun 1;130(6):2943-2952. doi: 10.1172/JCI134135. PMID: 32134398
Han X, Burger LL, Garcia-Galiano D, Sim S, Allen SJ, Olson DP, Myers MG Jr, Elias CF.2020Hypothalamic and Cell-Specific Transcriptomes Unravel a Dynamic Neuropil Remodeling in Leptin-Induced and Typical Pubertal Transition in Female Mice. iScience. 2020 Sep 16;23(10):101563. doi: 10.1016/j.isci.2020.101563. eCollection 2020 Oct 23. PMID: 33083731
Hull JM, O'Malley HA, Chen C, Yuan Y, Denomme N, Bouza AA, Anumonwo C, Lopez-Santiago LF, Isom LL.2020Excitatory and inhibitory neuron defects in a mouse model of Scn1b-linked EIEE52. Ann Clin Transl Neurol. 2020 Nov;7(11):2137-2149. doi: 10.1002/acn3.51205. Epub 2020 Sep 26. PMID: 32979291
Liu Y, Lin H, Jiang L, Shang Q, Yin L, Lin JD, Wu WS, Rui L.2020Hepatic Slug epigenetically promotes liver lipogenesis, fatty liver disease, and type 2 diabetes. J Clin Invest. 2020 Jun 1;130(6):2992-3004. doi: 10.1172/JCI128073. PMID: 32365055
Sutton AK, Gonzalez IE, Sadagurski M, Rajala M, Lu C, Allison MB, Adams JM, Myers MG, White MF, Olson DP.2020Paraventricular, subparaventricular and periventricular hypothalamic IRS4-expressing neurons are required for normal energy balance. Sci Rep. 2020 Mar 26;10(1):5546. doi: 10.1038/s41598-020-62468-z. PMID: 32218485
Bennett JA, Mastrangelo MA, Ture SK, Smith CO, Loelius SG, Berg RA, Shi X, Burke RM, Spinelli SL, Cameron SJ, Carey TE, Brookes PS, Gerszten RE, Sabater-Lleal M, de Vries PS, Huffman JE, Smith NL, Morrell CN, Lowenstein CJ.2020The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function. Nat Commun. 2020 Jul 13;11(1):3479. doi: 10.1038/s41467-020-17254-w. PMID: 32661250
Bosze B, Suarez-Navarro J, Soofi A, Lauderdale JD, Dressler GR, Brown NL.2020Multiple roles for Pax2 in the embryonic mouse eye. Dev Biol. 2021 Jan 9;472:18-29. doi: 10.1016/j.ydbio.2020.12.020. Online ahead of print. PMID: 33428890
Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FS, Camper SA.2020Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020 Aug 3;130(8):4501-4515. doi: 10.1172/JCI136745. PMID: 32453714
Chang Z, Zhao G, Zhao Y, Lu H, Xiong W, Liang W, Sun J, Wang H, Zhu T, Rom O, Guo Y, Fan Y, Chang L, Yang B, Garcia-Barrio MT, Lin JD, Chen YE, Zhang J.2020BAF60a Deficiency in Vascular Smooth Muscle Cells Prevents Abdominal Aortic Aneurysm by Reducing Inflammation and Extracellular Matrix Degradation. Arterioscler Thromb Vasc Biol. 2020 Oct;40(10):2494-2507. doi: 10.1161/ATVBAHA.120.314955. Epub 2020 Aug 13. PMID: 32787523
Chen D, Geng X, Lapinski PE, Davis MJ, Srinivasan RS, King PD.2020RASA1-driven cellular export of collagen IV is required for the development of lymphovenous and venous valves in mice. Development. 2020 Dec 7;147(23):dev192351. doi: 10.1242/dev.192351. PMID: 33144395
Cheng X, Peters ST, Pruett-Miller SM, Saunders TL, Joe B.2020In Vivo CRISPR/Cas9-Based Targeted Disruption and Knockin of a Long Noncoding RNA. Methods Mol Biol. 2021;2254:305-321. doi: 10.1007/978-1-0716-1158-6_19. PMID: 33326084
Cheung LYM, Camper SA.2020PROP1-Dependent Retinoic Acid Signaling Regulates Developmental Pituitary Morphogenesis and Hormone Expression. Endocrinology. 2020 Feb 1;161(2):bqaa002. doi: 10.1210/endocr/bqaa002. PMID: 31913463
Cote JL, Argetsinger LS, Flores A, Rupp AC, Cline JM, DeSantis LC, Bedard AH, Bagchi DP, Vander PB, Cacciaglia AM, Clutter ES, Chandrashekar G, MacDougald OA, Myers MG Jr, Carter-Su C.2020Deletion of the Brain-Specific _ and _ Isoforms of Adapter Protein SH2B1 Protects Mice From Obesity. Diabetes. 2020 Nov 19:db200687. doi: 10.2337/db20-0687. Online ahead of print. PMID: 33214137
Ding L, Li Q, Chakrabarti J, Munoz A, Faure-Kumar E, Ocadiz-Ruiz R, Razumilava N, Zhang G, Hayes MH, Sontz RA, Mendoza ZE, Mahurkar S, Greenson JK, Perez-Perez G, Hanh NTH, Zavros Y, Samuelson LC, Iliopoulos D, Merchant JL.2020MiR130b from Schlafen4+ MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer. Gut. 2020 Oct;69(10):1750-1761. doi: 10.1136/gutjnl-2019-318817. Epub 2020 Jan 24. PMID: 31980446
Emmer BT, Lascuna PJ, Tang VT, Kotnik EN, Saunders TL, Khoriaty R, Ginsburg D.2020Murine Surf4 is essential for early embryonic development. PLoS One. 2020 Jan 24;15(1):e0227450. doi: 10.1371/journal.pone.0227450. eCollection 2020. PMID: 31978056
Everett LA, Khoriaty RN, Zhang B, Ginsburg D.2020Altered phenotype in LMAN1-deficient mice with low levels of residual LMAN1 expression. Blood Adv. 2020 Nov 24;4(22):5635-5643. doi: 10.1182/bloodadvances.2020002523. PMID: 33196840
Golla JP, Kandyliari A, Tan WY, Chen Y, Orlicky DJ, Thompson DC, Shah YM, Vasiliou V.2020Interplay between APC and ALDH1B1 in a newly developed mouse model of colorectal cancer. Chem Biol Interact. 2020 Nov 1;331:109274. doi: 10.1016/j.cbi.2020.109274. Epub 2020 Sep 29. PMID: 33007288
He Y, Mi J, Olson A, Aldahl J, Hooker E, Yu EJ, Le V, Lee DH, Kim WK, Robins DM, Geradts J, Sun Z.2020Androgen receptor with short polyglutamine tract preferably enhances Wnt/_-catenin-mediated prostatic tumorigenesis. Oncogene. 2020 Apr;39(16):3276-3291. doi: 10.1038/s41388-020-1214-7. Epub 2020 Feb 24. PMID: 32089544
Jiang L, Su H, Wu X, Shen H, Kim MH, Li Y, Myers MG Jr, Owyang C, Rui L.2020Leptin receptor-expressing neuron Sh2b1 supports sympathetic nervous system and protects against obesity and metabolic disease. Nat Commun. 2020 Mar 23;11(1):1517. doi: 10.1038/s41467-020-15328-3. PMID: 32251290
Khoa LTP, Tsan YC, Mao F, Kremer DM, Sajjakulnukit P, Zhang L, Zhou B, Tong X, Bhanu NV, Choudhary C, Garcia BA, Yin L, Smith GD, Saunders TL, Bielas SL, Lyssiotis CA, Dou Y.2020Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation. Cell Stem Cell. 2020 Sep 3;27(3):441-458.e10. doi: 10.1016/j.stem.2020.06.005. Epub 2020 Jun 30. PMID: 32610040
Kim S, Khoriaty R, Li L, McClune M, Kalfa TA, Wu J, Peltier D, Fujiwara Oravecz-Wilson K, King RA, Ginsburg D, Reddy P.2020ER-to-Golgi transport and SEC23-dependent COPII vesicles regulate T cell alloimmunity. J Clin Invest. 2021 Jan 19;131(2):e136574. doi: 10.1172/JCI136574. PMID: 33463537
Lanigan TM, Kopera HC.2020Principles of Genetic Engineering. Genes (Basel). 2020 Mar 10;11(3):291. doi: 10.3390/genes11030291. PMID: 32164255
Liang T, Hu Y, Kawasaki K, Zhang H, Zhang C, Saunders TL, Simmer JP, Hu JC.2020Odontogenesis-associated phosphoprotein truncation blocks ameloblast transition into maturation in OdaphC41*/C41* mice. Sci Rep. 2021 Jan 13;11(1):1132. doi: 10.1038/s41598-020-80912-y. PMID: 33441959
Lindenmaier Z, Yee Y, Kinman A, Fernandes D, Ellegood J, Burton CL, Robins DM, Raznahan A, Arnold P, Lerch JP.2020Characterization of mice bearing humanized androgen receptor genes (h/mAr) varying in polymorphism length. Neuroimage. 2020 Nov 26;226:117594. doi: 10.1016/j.neuroimage.2020.117594. PMID: 33248253
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Matsushita Y, Nagata M, Kozloff KM, Welch JD, Mizuhashi K, Tokavanich N, Hallett SA, Link DC, Nagasawa T, Ono W, Ono N.2020A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration. Nat Commun. 2020 Jan 16;11(1):332. doi: 10.1038/s41467-019-14029-w. PMID: 31949165
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Mohamed FF, Ge C, Binrayes A, Franceschi RT.2020The Role of Discoidin Domain Receptor 2 in Tooth Development. J Dent Res. 2020 Feb;99(2):214-222. doi: 10.1177/0022034519892563. Epub 2019 Dec 23. PMID: 31869264
Morell RJ, Olszewski R, Tona R, Leitess S, Wafa TT, Taukulis I, Schultz JM, Thomason EJ, Richards K, Whitley BN, Hill C, Saunders T, Starost MF, Fitzgerald T, Wilson E, Ohyama T, Friedman TB, Hoa M.2020Noncoding Microdeletion in Mouse Hgf Disrupts Neural Crest Migration into the Stria Vascularis, Reduces the Endocochlear Potential, and Suggests the Neuropathology for Human Nonsyndromic Deafness DFNB39. J Neurosci. 2020 Apr 8;40(15):2976-2992. doi: 10.1523/JNEUROSCI.2278-19.2020. Epub 2020 Mar 9. PMID: 32152201
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Quan T, Xiang Y, Liu Y, Qin Z, Yang Y, Bou-Gharios G, Voorhees JJ, Dlugosz AA, Fisher GJ.2020Dermal Fibroblast CCN1 Expression in Mice Recapitulates Human Skin Dermal Aging. J Invest Dermatol. 2020 Aug 13:S0022-202X(20)31967-9. doi: 10.1016/j.jid.2020.07.019. Online ahead of print. PMID: 32800875
Soofi A, Kutschat AP, Azam M, Laszczyk AM, Dressler GR.2020Regeneration after acute kidney injury requires PTIP-mediated epigenetic modifications. JCI Insight. 2020 Feb 13;5(3):e130204. doi: 10.1172/jci.insight.130204. PMID: 31917689
Westrick RJ, R¿jkjaer LP, Yang AY, Roh MH, Siebert AE, Ginsburg D.2020Deficiency of plasminogen activator inhibitor-2 results in accelerated tumor growth. J Thromb Haemost. 2020 Nov;18(11):2968-2975. doi: 10.1111/jth.15054. Epub 2020 Oct 1. PMID: 32780555
Yao H, Hannum DF, Zhai Y, Hill SF, Albanus RD', Lou W, Skidmore JM, Sanchez G, Saiakhova A, Bielas SL, Scacheri P, Ljungman M, Parker SCJ, Martin DM.2020CHD7 promotes neural progenitor differentiation in embryonic stem cells via altered chromatin accessibility and nascent gene expression. Sci Rep. 2020 Oct 15;10(1):17445. doi: 10.1038/s41598-020-74537-4. PMID: 33060836
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J Clin Invest.		2020Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. 2020 May 26:136745. doi: 10.1172/JCI136745. Online ahead of print.
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Su RC, Warner EA, Breidenbach JD, Lad A, Blomquist TM, Kleinhenz AL, Modyanov N, Malhotra D, Kennedy DJ, Haller ST.2020CD40 Receptor Knockout Protects against Microcystin-LR (MC-LR) Prolongation and Exacerbation of Dextran Sulfate Sodium (DSS)-Induced Colitis.
Biomedicines. 2020 Jun 2;8(6):E149. doi: 10.3390/biomedicines8060149.
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Flak JN, Goforth PB, Dell'Orco J, Sabatini PV, Li C, Bozadjieva N, Sorensen M, Valenta A, Rupp A, Affinati AH, Cras-Méneur C, Ansari A, Sacksner J, Kodur N, Sandoval DA, Kennedy RT, Olson DP, Myers MG Jr.2020Ventromedial hypothalamic nucleus neuronal subset regulates blood glucose independently of insulin.
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Zhu L, Tang Y, Li XY, Keller ET, Yang J, Cho JS, Feinberg TY, Weiss SJ.2020Osteoclast-mediated bone resorption is controlled by a compensatory network of secreted and membrane-tethered metalloproteinases.
Sci Transl Med. 2020 Feb 5;12(529):eaaw6143. doi: 10.1126/scitranslmed.aaw6143.
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Lovat F, Nigita G, Distefano R, Nakamura T, Gasparini P, Tomasello L, Fadda P, Ibrahimova N, Catricalà S, Palamarchuk A, Caligiuri MA, Gallì A, Malcovati L, Minden MD, Croce CM.2020Combined loss of function of two different loci of miR-15/16 drives the pathogenesis of acute myeloid leukemia.
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Song JY, Pineault KM, Dones JM, Raines RT, Wellik DM.2020Hox genes maintain critical roles in the adult skeleton. Proc Natl Acad Sci U S A. 2020 Mar 13. pii: 201920860. doi: 10.1073/pnas.1920860117. [Epub ahead of print]
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El-Zaatari M , Bishu S, Zhang M, Grasberger H, Hou G, Haley H, Humphries B, Syu LJ, Dlugosz AA, Luker K, Luker GD, Eaton K, Kamada N, Cascalho M, Kao JY.2020Aim2-mediated/IFN-β-independent regulation of gastric metaplastic lesions via CD8+ T cells. JCI Insight. 2020 Mar 12;5(5). pii: 94035. doi: 10.1172/jci.insight.94035. PMID: 32053518
Matsushita Y, Nagata M, Kozloff KM, Welch JD, Mizuhashi K, Tokavanich N, Hallett SA, Link DC, Nagasawa T, Ono W, Ono N.2020A Wnt-mediated transformation of the bone marrow stromal cell identity orchestratesskeletal regeneration. Nat Commun.11:332. PMID: 31949165
Yu H, Thompson Z, Kiran S, Jones GL, Mundada L; Surbhi , Rubinstein M, Low MJ.2020Expression of a hypomorphic Pomc allele alters leptin dynamics during late pregnancy. J Endocrinol. 2020 Apr;245(1):115-127. doi: 10.1530/JOE-19-0576.
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Ding L, Li Q, Chakrabarti J, Munoz A, Faure-Kumar E, Ocadiz-Ruiz R, Razumilava N, Zhang G, Hayes MH, Sontz RA, Mendoza ZE, Mahurkar S, Greenson JK, Perez-Perez G, Hanh NTH, Zavros Y, Samuelson LC, Iliopoulos D, Merchant JL.2020MiR130b from Schlafen4+ MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer. Gut. 2020 Jan 24. pii: gutjnl-2019-318817. doi: 10.1136/gutjnl-2019-318817. [Epub ahead of print] PMID: 31980446
Zheng X, Arias EB, Qi NR, Saunders TL, Cartee GD.2020In vivo glucoregulation and tissue-specific glucose uptake in female Akt substrate 160 kDa knockout rats. PLoS One. 2020 Feb 13;15(2):e0223340. doi: 10.1371/journal.pone.0223340. eCollection 2020. PMID: 32053588
Zhu L, Tang Y, Li XY, Keller ET, Yang J, Cho JS, Feinberg TY2020Osteoclast-mediated bone resorption is controlled by a compensatory network of secreted and membrane-tethered metalloproteinases. Sci Transl Med. 2020 Feb 5;12(529). pii: eaaw6143. doi: 10.1126/scitranslmed.aaw6143. PMID: 32024800
Demireva EY, Xie H, Flood ED, Thompson JM, Seitz BM, Watts SW.2019Creation of the 5-hydroxytryptamine receptor 7 knockout rat as a tool for cardiovascular research. Physiol Genomics. 2019 Jul 1;51(7):290-301. doi: 10.1152/physiolgenomics.00030.2019. Epub 2019 May 24.
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Hu Y, Smith DE.2019In Silico Prediction of the Absorption and Disposition of Cefadroxil in Humans using an Intestinal Permeability Method Scaled from Humanized PepT1 Mice. Drug Metab Dispos. 2019 Mar;47(3):173-183. doi: 10.1124/dmd.118.084236. Epub 2018 Dec 28. PMID: 30593545
Keeley TM, Horita N, Samuelson LC.2019Tamoxifen-Induced Gastric Injury: Effects of Dose and Method of Administration. Cell Mol Gastroenterol Hepatol. 2019;8(3):365-367. doi: 10.1016/j.jcmgh.2019.06.007. Epub 2019 Jun 21. No abstract available.
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Yuan Y, O'Malley HA, Smaldino MA, Bouza AA, Hull JM, Isom LL.2019Delayed maturation of GABAergic signaling in the Scn1a and Scn1b mouse models of Dravet Syndrome. Sci Rep. 2019 Apr 17;9(1):6210. doi: 10.1038/s41598-019-42191-0. PMID: 30996233
O'Malley HA, Hull JM, Clawson BC, Chen C, Owens-Fiestan G, Jameson MB, Aton SJ, Parent JM, Isom LL.2019Scn1b deletion in adult mice results in seizures and SUDEP. Ann Clin Transl Neurol. 2019 May 8;6(6):1121-1126. doi: 10.1002/acn3.785. eCollection 2019 Jun. PMID: 31211177
Bashir B, Merlino DJ, Rappaport JA, Gnass E, Palazzo JP, Feng Y, Fearon ER, Snook AE, Waldman SA.2019Silencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated, and MSI colorectal neoplasia. Hum Pathol. 2019 May;87:103-114. doi: 10.1016/j.humpath.2018.11.032. Epub 2019 Feb 2. PMID: 30716341
Tang J, Feng Y, Kuick R, Green M, Green M, Sakamoto N, Kurosu Y, Lin J, Cho KR, Fearon ER.2019Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis. Lab Invest. 2019 Oct;99(10):1454-1469. doi: 10.1038/s41374-019-0269-y. Epub 2019 May 31. PMID: 31148594
McCool KW, Freeman ZT, Zhai Y, Wu R, Hu K, Liu CJ, Tomlins SA, Fearon ER, Magnuson B, Kuick R, Cho KR.2019Murine Oviductal High-Grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles, and Immune Microenvironment of Their Human Counterparts. Cancer Res. 2020 Feb 15;80(4):877-889. doi: 10.1158/0008-5472.CAN-19-2558. Epub 2019 Dec 5. PMID: 31806642
Billi AC, Gharaee-Kermani M, Fullmer J, Tsoi LC, Hill BD, Gruszka D, Ludwig J, Xing X, Estadt S, Wolf SJ, Rizvi SM, Berthier CC, Hodgin JB, Beamer MA, Sarkar MK, Liang Y, Uppala R, Shao S, Zeng C, Harms PW, Verhaegen ME, Voorhees JJ, Wen F, Ward NL, Dlugosz AA, Kahlenberg JM, Gudjonsson JE.2019The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity. JCI Insight. 2019 Apr 18;4(8). pii: 127291. doi: 10.1172/jci.insight.127291. eCollection 2019 Apr 18. PMID: 30996136
Kimball AS, Davis FM, denDekker A, Joshi AD, Schaller MA, Bermick J, Xing X, Burant CF, Obi AT, Nysz D, Robinson S, Allen R, Lukacs NW, Henke PK, Gudjonsson JE, Moore BB, Kunkel SL, Gallagher KA.2019The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair. Immunity. 2019 Aug 20;51(2):258-271.e5. doi: 10.1016/j.immuni.2019.06.015. Epub 2019 Jul 23. PMID: 31350176
Bunton-Stasyshyn RKA, Wagnon JL, Wengert ER, Barker BS, Faulkner A, Wagley PK, Bhatia K, Jones JM, Maniaci MR, Parent JM, Goodkin HP, Patel MK, Meisler MH. 2019Prominent role of forebrain excitatory neurons in SCN8A encephalopathy. Brain. 2019 Feb 1;142(2):362-375. PMID: 30601941
Engelke MF, Waas B, Kearns SE, Suber A, Boss A, Allen BL, Verhey KJ. 20192019. Acute Inhibition of Heterotrimeric Kinesin-2 Function Reveals Mechanisms of IntraflagellarTransport in Mammalian Cilia. Curr Biol. 29:1137-1148. PMID: 30905605
Fleming JT, Brignola E, Chen L, Guo Y, Zhao S, Wang Q, Li B, Correa H, Ermilov AN, Dlugosz AA, Chiang C.2019Insight into the Etiology of Undifferentiated Soft Tissue Sarcomas from a Novel Mouse Model. Mol Cancer Res. 2019 Jan 25. [Epub ahead of print]. PMID: 30683671
Flores A, Argetsinger LS, Stadler LKJ, Malaga AE, Vander PB, DeSantis LC, Joe RM, Cline JM, Keogh JM, Henning E, Barroso I, Mendes de Oliveira E, Chandrashekar G, Clutter ES, Hu Y, Stuckey J, Farooqi IS, Myers MG Jr, Carter-Su C.2019Crucial Role of the SH2B1 PH Domain for the Control of Energy Balance. Diabetes. 2019 Aug 22. pii: db190608. doi: 10.2337/db19-0608. [Epub ahead of print] PMID: 31439647
McCabe IC, Fedorko A, Myers MG Jr, Leinninger G, Scheller E, McCabe LR.2019Novel leptin receptor signaling mutants identify location and sex-dependent modulation of bone density, adiposity, and growth. J Cell Biochem. 2019 Mar;120(3):4398-4408. PMID: 30269370
Pan W, Allison MB, Sabatini P, Rupp A, Adams J, Patterson C, Jones JC, Olson DP, Myers MG Jr.2019Transcriptional and physiological roles for STAT proteins in leptin action. Mol Metab. 2019 Jan 24. pii: S2212-8778(18)31242-0. PMID: 30718218
Pei H, Patterson CM, Sutton AK, Burnett KH, Myers MG Jr, Olson DP.2019Lateral Hypothalamic Mc3R-Expressing Neurons Modulate Locomotor Activity, Energy Expenditure, and Adiposity in Male Mice. Endocrinology. 2019 Feb 1;160(2):343-358. PMID: 30541071
Pettibone JR, Yu JY, Derman RC, Faust TW, Hughes ED, Filipiak WE, Saunders TL, Ferrario CR, Berke JD.2019Knock-in rat lines with Cre recombinase at the dopamine D1 and adenosine 2a receptor loci. eNeuro. 2019 Aug 26. pii: ENEURO.0163-19.2019. doi: 10.1523/ENEURO.0163-19.2019. [Epub ahead of print] PMID: 31451604
Sun Y, Oravecz-Wilson K, Bridges S, McEachin R, Wu J, Kim SH, Taylor A, Zajac C, Fujiwara H, Peltier DC, Saunders T, Reddy P.2019miR-142 controls metabolic reprogramming that regulates dendritic cell activation. J Clin Invest. 130. pii: 123839. PMID: 30958798
Wang S, Walton KD, Gumucio DL.2019Signals and forces shaping organogenesis of the small intestine. Curr Top Dev Biol. 2019;132:31-65. PMID: 30797512
Yin Y, Xie CM, Li H, Tan M, Chen G, Schiff R, Xiong X, Sun Y.2019The FBXW2-MSX2-SOX2 axis regulates stem cell property and drug resistance of cancer cells. Proc Natl Acad Sci U S A. 2019 Sep 23. pii: 201905973. doi: 10.1073/pnas.1905973116. [Epub ahead of print]. PMID: 31548378
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Khoriaty R, Hesketh GG, Bernard A, Weyand AC, Mellacheruvu D, Zhu G, Hoenerhoff MJ, McGee B, Everett L, Adams EJ, Zhang B, Saunders TL, Nesvizhskii AI, Klionsky DJ, Shavit JA, Gingras AC, Ginsburg D.2018Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7748-E7757. doi: 10.1073/pnas.1805784115. Epub 2018 Jul 31. PMID: 30065114
Pan W, Adams JM, Allison MB, Patterson C, Flak JN, Jones J, Strohbehn G, Trevaskis J, Rhodes CJ, Olson DP, Myers MG Jr.2018Essential Role for Hypothalamic Calcitonin Receptor‒Expressing Neurons in the Control of Food Intake by Leptin.
Endocrinology. 2018 Apr 1;159(4):1860-1872. doi: 10.1210/en.2017-03259.
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Allison MB, Pan W, MacKenzie A, Patterson C, Shah K, Barnes T, Cheng W, Rupp A, Olson DP, Myers MG Jr.2018Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action. Diabetes. 2018 Jun;67(6):1093-1104. PMID: 29535089
Allan CM, Heizer PJ, Tu Y, Sandoval NP, Jung RS, Morales JE, Sajti E, Troutman TD, Saunders TL, Cusanovich DA, Beigneux AP, Romanoski CE, Fong LG, Young SG.2018An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner. J Lipid Res. 2018 Dec 31. pii: jlr.M091322. doi: 10.1194/jlr.M091322. [Epub ahead of print]. PMID: 30598475
Bélanger C, Bérubé-Simard FA, Leduc E, Bernas G, Campeau PM, Lalani SR, Martin DM, Bielas S, Moccia A, Srivastava A, Silversides DW, Pilon N. 2018Dysregulation of cotranscriptional alternative splicing underlies CHARGE syndrome. Proc Natl Acad Sci U S A. 115:E620-E629.
Bodur C, Kazyken D, Huang K, Ekim Ustunel B, Siroky KA, Tooley AS, Gonzalez IE, Foley DH, Acosta-Jaquez HA, Barnes TM, Steinl GK, Cho KW, Lumeng CN, Riddle SM, Myers MG Jr, Fingar DC.2018The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists. EMBO J. 2018 Jan 4;37(1):19-38. PMID: 29150432
Chen C, Holth JK, Bunton-Stasyshyn R, Anumonwo CK, Meisler MH, Noebels JL, Isom LL.2018Mapt deletion fails to rescue premature lethality in two models of sodium channel epilepsy. Ann Clin Transl Neurol. 2018 Jul 5;5(8):982-987. PMID: 30128323
Cho KR.2018Is "Ovarian" Cancer a Misnomer? Exploring Ovarian Cancer Origins in the Muse. Trans Am Clin Climatol Assoc. 2018;129:40-47.
Codner GF, Mianné J, Caulder A, Loeffler J, Fell R, King R, Allan AJ, Mackenzie M, Pike FJ, McCabe CV, Christou S, Joynson S, Hutchison M, Stewart ME, Kumar S, Simon MM, Agius L, Anstee QM, Volynski KE, Kullmann DM, Wells S, Teboul L. 2018Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants. BMC Biol. 16:70.
Cunningham GM, Flores LC, Roman MG, Cheng C, Dube S, Allen C, Valentine JM, Hubbard GB, Bai Y, Saunders TL, Ikeno Y. 2018Thioredoxin overexpression in both the cytosol and mitochondria accelerates age-related disease and shortens lifespan in male C57BL/6 mice. Geroscience. 2018 Aug 18. doi: 10.1007/s11357-018-0039-6. [Epub ahead of print]
Epling D, Hu Y, Smith DE.2018Evaluating the intestinal and oral absorption of the prodrug valacyclovir in wildtype and huPepT1 transgenic mice. Biochem Pharmacol. 155:1-7. 
Feinberg TY, Zheng H, Liu R, Wicha MS, Yu SM, Weiss SJ. 2018Divergent Matrix-Remodeling Strategies Distinguish Developmental from Neoplastic Mammary Epithelial Cell Invasion Programs. Dev Cell. 2018 Oct 22;47(2):145-160.e6. PMID: 30269950
Fearon ER.2018Molecular Features and Mouse Models of Colorectal Cancer. Trans Am Clin Climatol Assoc. 2018;129:56-62.
Goldstein CA, O'Brien LM, Bergin IL, Saunders TL.2018The effect of repeated light-dark shifts on uterine receptivity and early gestation in mice undergoing embryo transfer. Syst Biol Reprod Med. 64:103-111. 
Grimley E, Dressler GR. 2018Are Pax proteins potential therapeutic targets in kidney disease and cancer? 2018. Kidney Int. 94:259-267.
Gu B, Posfai E, Rossant J. 2018Efficient generation of targeted large insertions by microinjection into two-cell-stage mouse embryos. Nat Biotechnol. 36:632-637.
Hrycaj SM, Marty-Santos L, Cebrian C, Rasky AJ, Ptaschinski C, Lukacs NW, Wellik DM.2018Hox5 genes direct elastin network formation during alveologenesis by regulatingmyofibroblast adhesion. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10605-E10614. PMID: 30348760
Hull JM, Isom LL.2018Voltage-gated sodium channel β subunits: The power outside the pore in brain development and disease. Neuropharmacology. 132:43-57. 
Hu Y, Song F, Jiang H, Nuñez G, Smith DE.2018SLC15A2 and SLC15A4 Mediate the Transport of Bacterially Derived Di/Tripeptides To Enhance the Nucleotide-Binding Oligomerization Domain-Dependent Immune Response in Mouse Bone Marrow-Derived Macrophages. J Immunol. 2018 Jul 15;201(2):652-662. PMID: 29784761
Jiang L, Su H, Keogh JM, Chen Z, Henning E, Wilkinson P, Goodyer I, Farooqi IS, Rui L.2018Neural deletion of Sh2b1 results in brain growth retardation and reactive aggression. FASEB J. 2018 Apr;32(4):1830-1840. PMID: 29180441
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Kruger AN, Ellison Q, Brogley MA, Gerlinger ER, Mueller JL. 2018Male mice with large inversions or deletions of X-chromosome palindrome arms are fertile and express their associated genes during post-meiosis.Sci Rep. 8:8985.
Lovat F, Fassan M, Sacchi D, Ranganathan P4, Palamarchuk A, Bill M, Karunasiri M, Gasparini P, Nigita G, Distefano R, Veneziano D, Dorrance AM, Garzon R, Croce CM.2018Knockout of both miR-15/16 loci induces acute myeloid leukemia. Proc Natl Acad Sci U S A. 2018 Nov 26. pii: 201814980. doi: 10.1073/pnas.1814980115. [Epub ahead of print]. PMID: 30478046
Liu Y, Jiang L, Sun C, Ireland N, Shah YM, Liu Y, Rui L.2018Insulin/Snail1 axis ameliorates fatty liver disease by epigenetically suppressing lipogenesis. Nat Commun. 2018 Jul 16;9(1):2751. PMID: 30013137
Liu M, Weiss MA, Arunagiri A, Yong J, Rege N, Sun J, Haataja L, Kaufman RJ, Arvan P.2018Biosynthesis, structure, and folding of the insulin precursor protein. Diabetes Obes Metab. 2018 Sep;20 Suppl 2:28-50. PMID: 30230185
Ma X, Das NK, Castillo C, Gourani A, Perekatt AO, Verzi MP, Shah YM.2018SMAD family member 3 (SMAD3) and SMAD4 repress HIF2a-dependent iron-regulatory genes. J Biol Chem. 2019 Jan 18. pii: jbc.RA118.005549. PMID: 30659096
Ma X, Zhang H, Xue X, Shah YM.2018Hypoxia-inducible factor 2α (HIF-2α) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity. J Biol Chem. 292:17046-17056.
Mancuso P, Curtis JL, Freeman CM, Peters-Golden M, Weinberg JB, Myers MG. 2018Ablation of the Leptin receptor in Myeloid Cells Impairs Pulmonary Clearance of Streptococcus Pneumoniae and Alveolar Macrophage Bactericidal Function. Am J Physiol Lung Cell Mol Physiol. 315:L78-L86.
Marie C, Clavairoly A, Frah M, Hmidan H, Yan J, Zhao C, Van Steenwinckel J, Daveau R, Zalc B, Hassan B, Thomas JL, Gressens P, Ravassard P, Moszer I, Martin DM, Lu QR, Parras C. 2018Oligodendrocyte precursor survival and differentiation requires chromatinremodeling by Chd7 and Chd8. Proc Natl Acad Sci U S A. 115(35):E8246-E8255. PMID: 30108144
Miyasaka Y, Uno Y, Yoshimi K, Kunihiro Y, Yoshimura T, Tanaka T, Ishikubo H, Hiraoka Y, Takemoto N, Tanaka T, Ooguchi Y, Skehel P, Aida T, Takeda J, Mashimo T. 2018CLICK: one-step generation of conditional knockout mice. BMC Genomics. 19:318.
Moriguchi T, Hoshino T, Rao A, Yu L, Takai J, Uemura S, Ise K, Nakamura Y, Lim KC, Shimizu R, Yamamoto M, Engel JD. 2018A Gata3 3' distal otic vesicle enhancer directs inner ear-specific Gata3 expression. Mol Cell Biol. 2018 Aug 20. pii: MCB.00302-18. doi: 10.1128/MCB.00302-18. [Epub ahead of print]  
Nath SR, Yu Z, Gipson TA, Marsh GB, Yoshidome E, Robins DM, Todi SV, Housman DE, Lieberman AP.  2018Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. J Clin Invest. 2018 Aug 1;128(8):3630-3641. 
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Oravecz-Wilson KI, Kiel MJ, Li L, Rao DS, Saint-Dic D, Kumar PD, Provot MM, Hankenson KD, Reddy VN, Lieberman AP, Morrison SJ, Ross TS. 2004 Huntingtin Interacting Protein 1 mutations lead to abnormal hematopoiesis, spinal defects and cataracts. Hum Mol Genet. 13:851-67.
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Strettoi E, Mears AJ, Swaroop A. 2004Recruitment of the rod pathway by cones in the absence of rods. J Neurosci. 24:7576-82.
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Van Keuren ML, Saunders TL. 2004Rederivation of Transgenic and Gene-Targeted Mice by Embryo Transfer. Transgenic Res. 13:363-371.
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Wei Q, Lu XY, Liu L, Schafer G, Shieh KR, Burke S, Robinson TE, Watson SJ, Seasholtz AF, Akil H. 2004Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. Proc Natl Acad Sci U S A. 101:11851-6.
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Ben-Yosef T, Belyantseva IA, Saunders TL, Hughes ED, Kawamoto K, Van Itallie CM, Beyer LA, Halsey K, Gardner DJ, Wilcox ER, Rasmussen J, Anderson JM, Dolan DF, Forge A, Raphael Y, Camper SA, Friedman TB. 2003Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration. Hum Mol Genet. 12(16):2049-2061.
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Gopalakrishnan R, Thomas PE, Benson MD, Wang D, Franceschi RT. 2003A homeodomain protein binding element in the bone sialoprotein promoter is critical for tissue-specific expression in bone. Connect Tissue Res. 44:154-60.
Grachtchouk V, Grachtchouk M, Lowe L, Johnson T, Wei L, Wang A, de Sauvage F, Dlugosz AA.2003The magnitude of hedgehog signaling activity defines skin tumor phenotype.EMBO J. 22:2741-51.
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Krebs CJ, Larkins LK, Price R, Tullis KM, Miller RD, Robins DM. 2003Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression. Genes Dev. 17:2664-74.
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McLerie M, Lopatin A.2003Dominant-negative suppression of I(K1) in the mouse heart leads to altered cardiac excitability. J Mol Cell Cardiol. 35:367-78.
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Norman LP, Jiang W, Han X, Saunders TL, Bond JS.2003Targeted disruption of the meprin Beta gene in mice leads to underrepresentation of knockout mice and changes in renal gene expression profiles. Mol Cell Biol. (4):1221-30.
Samuelson LC, Hinkle KL. 2003Insights into the regulation of gastric Acid secretion through analysis of genetically engineered mice. Annu Rev Physiol. 65:383-400.
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Sun FJ, Kaur S, Ziemer D, Banerjee S, Samuelson LC, De Lisle RC. 2003Decreased gastric bacterial killing and up-regulation of protective genes in small intestine in gastrin-deficient mouse. Dig Dis Sci. 48:976-85.
Sun H, Yang TL, Yang A, Wang X, Ginsburg D. 2003The murine platelet and plasma factor V pools are biosynthetically distinct and sufficient for minimal hemostasis. Blood. 102:2856-61.
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Van Mater D, Kolligs FT, Dlugosz AA, Fearon ER. 2003Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice. Genes Dev. 17:1219-24.
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Eitzman DT, Westrick RJ, Bi X, Manning SL, Wilkinson JE, Broze GJ, Ginsburg D. 2002Lethal perinatal thrombosis in mice resulting from the interaction of tissue factor pathway inhibitor deficiency and factor V Leiden. Circulation. 105(18):2139-42.
Erdmann I, Scheidegger EP, Koch FK, Heinzerling L, Odermatt B, Burg G, Lowe JB, Kundig TM. 2002Fucosyltransferase VII-deficient mice with defective E-, P-, and L-selectin ligands show impaired CD4+ and CD8+ T cell migration into the skin, but normal extravasation into visceral organs. J Immunol. 168: 2139-2146.
Innis JW, Margulies EH, Kardia S. 2002Integrative biology and the developing limb bud. Evol Dev. 4: 378-389.
Ishida S, Lee J, Thiele DJ, Herskowitz I. 2002Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals. Proc Natl Acad Sci U S A. 99:14298-302.
Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ. 2002IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev. 16:452-66.
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Martin DM, Skidmore JM, Fox SE, Gage PJ, Camper SA.2002Pitx2 distinguishes subtypes of terminally differentiated neurons in the developing mouse neuroepithelium. Dev Biol. 252:84-99.
Michele DE, Gomez CA, Hong KE, Westfall MV, Metzger JM.2002Cardiac dysfunction in hypertrophic cardiomyopathy mutant tropomyosin mice is transgene-dependent, hypertrophy-independent, and improved by beta-blockade. Circ Res. 91:255-262.
Moeller MJ, Sanden SK, Soofi A, Wiggins RC, Holzman LB. 2002Two Gene Fragments that Direct Podocyte-Specific Expression in Transgenic Mice. J Am Soc Nephrol. 13:1561-1567.
Pendl GG, Robert C, Steinert M, Thanos R, Eytner R, Borges E, Wild MK, Lowe JB, Fuhlbrigge RC, Kupper TS, Vestweber D, Grabbe S. 2002Immature mouse dendritic cells enter inflamed tissue, a process that requires E- and P-selectin, but not P-selectin glycoprotein ligand 1. Blood. 99(3):946-56.
Peng L, Bhatia N, Parker AC, Zhu Y, Fay WP.2002Endogenous vitronectin and plasminogen activator inhibitor-1 promote neointima formation in murine carotid arteries. Arterioscler Thromb Vasc Biol. 22(6):934-9.
Raetzman LT, Ward R, Camper SA. 2002Lhx4 and Prop1 are required for cell survival and expansion of the pituitary primordia. Development. 129: 4229-4239.
Sheng H, Goich S, Wang A, Grachtchouk M, Lowe L, Mo R, Lin K, de Sauvage FJ, Sasaki H, Hui CC, Dlugosz AA. 2002Dissecting the oncogenic potential of Gli2: deletion of an NH(2)-terminal fragment alters skin tumor phenotype. Cancer Res. 62: 5308-16.
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Domino SE, Zhang L, Gillespie PJ, Saunders TL, Lowe, JB.2001Deficiency of reproductive tract alpha(1,2)fucosylated glycans and normal fertility in mice with targeted deletions of the FUT1 or FUT2 alpha(1,2)fucosyltransferase locus. Molec. Cell. Biol. 21:8336-8345.
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Homeister JW, Thall AD, Petryniak B, Maly P, Rogers CE, Smith PL, Kelly RJ, Gersten KM, Askari SW, Cheng G, Smithson G, Marks RM, Misra AK, Hindsgaul O, von Andrian UH, Lowe JB. 2001The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing. Immunity. 15:115-26.
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Mears AJ, Kondo M, Swain PK, Takada Y, Bush RA, Saunders TL, Sieving PA, Swaroop A.2001Nrl is required for rod photoreceptor development. Nat Genet. 29:447-52.
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Scheuner D, Song B, McEwen E, Liu C, Laybutt R, Gillespie P, Saunders T, Bonner-Weir S, Kaufman RJ.2001Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell. 7:1165-76.
Seasholtz AF, Burrows HL, Karolyi IJ, Camper SA.2001Mouse models of altered CRH-binding protein expression. 22:743-51.
Smithson G, Rogers CE, Smith PL, Scheidegger EP, Petryniak B, Myers JT, Kim DS, Homeister JW, Lowe JB.2001Fuc-TVII is required for T helper 1 and T cytotoxic 1 lymphocyte selectin ligand expression and recruitment in inflammation, and together with Fuc-TIV regulates naive T cell trafficking to lymph nodes. J Exp Med. 194:601-14.
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Zhao L. Bakke M. Krimkevich Y. Cushman LJ. Parlow AF. Camper SA. Parker KL.2001Steroidogenic factor 1 (SF1) is essential for pituitary gonadotrope function. Development. 128(2):147-54.
Zhao L, Bakke M, Krimkevich Y, Cushman LJ, Parlow AF, Camper SA, Parker KL.  2001Hypomorphic phenotype in mice with pituitary-specific knockout of steroidogenic factor 1. Genesis. 30(2):65-9.
Adams K. Ackerly H. Cunningham K. Dunnick W.2000A DNase I hypersensitive site near the murine gamma1 switch region contributes to insertion site independence of transgenes and modulates the amount of transcripts induced by CD40 ligation. International Immunology. 12(12):1705-13.
Ahmad A. Brinson M. Hodges BL. Chamberlain JS. Amalfitano A.2000Mdx mice inducibly expressing dystrophin provide insights into the potential of gene therapy for duchenne muscular dystrophy. Human Molecular Genetics. 9(17):2507-15.
Crawford GE. Faulkner JA. Crosbie RH. Campbell KP. Froehner SC. Chamberlain JS.2000Assembly of the dystrophin-associated protein complex does not require the dystrophin COOH-terminal domain. Journal of Cell Biology. 150(6):1399-410.
Cui J. Eitzman DT. Westrick RJ. Christie PD. Xu ZJ. Yang AY. Purkayastha AA. Yang TL. Metz AL. Gallagher KP. Tyson JA. Rosenberg RD. Ginsburg D.2000Spontaneous thrombosis in mice carrying the factor V Leiden mutation. Blood. 96(13):4222-6.
Cushman LJ. Burrows HL. Seasholtz AF. Lewandoski M. Muzyczka N. Camper SA.2000Cre-mediated recombination in the pituitary gland. Genesis: the Journal of Genetics & Development. 28(3-4):167-74.
Disatnik MH. Chamberlain JS. Rando TA. 2000Dystrophin mutations predict cellular susceptibility to oxidative stress. Muscle & Nerve. 23(5):784-92.
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Escayg A., De Waard, M., Lee, D.D., Bichet, D., Wolf, P., Mayer, T., Johnston, J., Baloh, R., Sander, T. and Meisler, M.H2000Coding and noncoding variation of the human calcium channel 4 subunit gene CACNB4 in patients with idiopathic generalized epilepsy and episodic ataxia. Am. J. Hum. Genet. 66:1531–1539.
Grachtchouk M, Mo R, Yu S, Zhang X, Sasaki H, Hui Cc, Dlugosz AA.2000Basal cell carcinomas in mice overexpressing Gli2 in skin. Nature Genetics 24:216-217.
Kurachi K, Kurachi S. 2000Genetic mechanisms of age regulation of blood coagulation: factor IX model.Arterioscler Thromb Vasc Biol. 20:902-906.
Kurachi K, Zhang K, Ameri A, Huo J, Atoda H, Kurachi S.2000Genetic and molecular mechanisms of age regulation (homeostasis) of blood coagulation. IUBMB Life. 49:189-96.
Lynch GS, Rafael JA, Chamberlain JS, Faulkner JA. 2000Contraction-induced injury to single permeabilized muscle fibers from mdx, transgenic mdx, and control mice.  Am J Physiol Cell Physiol. 279(4):C1290-4.
Moeller MJ, Kovari IA, Holzman LB.2000Evaluation of a new tool for exploring podocyte biology: mouse Nphs1 5′ flanking region drives LacZ expression in podocytes. J Am Soc Nephrol. 11(12):2306-14.
Post LC, Margulies EH, Kuo A, Innis JW.2000Severe limb defects in Hypodactyly mice result from the expression of a novel, mutant HOXA13 protein. Dev Biol 217:290-300.
Tanaka M, Yamasaki N, Izumo S. 2000Phenotypic characterization of the murine Nkx2.6 homeobox gene by gene targeting. Mol Cell Biol. 20:2874-9.
Wells AD. Li XC. Li Y. Walsh MC. Zheng XX. Wu Z. Nunez G. Tang A. Sayegh M. Hancock WW. Strom TB. Turka LA.2000Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance. Nature Medicine. 5(11):1303-7.
Weninger W, Ulfman LH, Cheng G, Souchkova N, Quackenbush EJ, Lowe JB, von Andrian UH.2000Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels.  Immunity. 12:665-676.
Wharram BL. Goyal M. Gillespie PJ. Wiggins JE. Kershaw DB. Holzman LB. Dysko RC. Saunders TL. Samuelson LC. Wiggins RC.2000Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate. Journal of Clinical Investigation. 106:1281-90.
Yang TL, Cui J, Taylor JM, Yang A, Gruber SB, Ginsburg D. 2000Rescue of fatal neonatal hemorrhage in factor V deficient mice by low level transgene expression. Thromb Haemost. 83:70-77.
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Beurskens FJ, Kuenen JD, Hofhuis F, Fluit AC, Robins DM, Van Dijk H. 1999Sex-limited protein: in vitro and in vivo functions. Clin Exp Immunol. 116(3):395-400.
Collins JT, Dunnick WA. 1999Cutting edge: IFN-gamma regulated germline transcripts are expressed from gamma2a transgenes independently of the heavy chain 3′ enhancers. J Immunol. 163:5758-5762.
Dougherty KM, Pearson JM, Yang AY, Westrick RJ, Baker MS, Ginsburg D. 1999The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival. Proc Natl Acad Sci U S A. 96:686-91.
Fay WP, Parker AC, Ansari MN, Zheng X, Ginsburg D. 1999Vitronectin inhibits the thrombotic response to arterial injury in mice. Blood. 93:1825-30.
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Karolyi IJ, Burrows HL, Ramesh TM, Nakajima M, Lesh JS, Seong E, Camper SA, Seasholtz AF. 1999Altered anxiety and weight gain in corticotropin-releasing hormone-binding protein-deficient mice.Proc Natl Acad Sci U S A. 96(20):11595-11600.
Lacourse KA, Swanberg LJ, Gillespie PJ, Rehfeld JF, Saunders TL, Samuelson LC.1999Pancreatic function in CCK-deficient mice: adaptation to dietary protein does not require CCK. Am J Physiol. 276:G1302-309.
Lay JM, Gillespie PJ, Samuelson LC.1999Murine prenatal expression of cholecystokinin in neural crest, enteric neurons, and enteroendocrine cells. Developmental Dynamics. 216:290-200.
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Mohlke KL, Purkayastha AA, Westrick RJ, Smith PL, Petryniak B, Lowe JB, Ginsburg D.1999Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase. Cell 96:111-120.
Stahl JH, Kendall SK, Brinkmeier ML, Greco TL, Watkins-Chow DE, Campos-Barros A, Lloyd RV, Camper SA.1999Thyroid hormone is essential for pituitary somatotropes and lactotropes. Endocrinology. 140:1884-1892.
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Tanaka M, Chen Z, Bartunkova S, Yamasaki N, Izumo S.1999The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development. 126(6):1269-80.
Türkay A , Saunders TL, Kurachi K.1999Intrauterine gene transfer: gestational stage-specific gene delivery in mice. Gene Therapy. 6:1685-1694.
Xiao JH, Feng X, Di W, Peng ZH, Li LA, Chambon P, Voorhees JJ.1999Identification of heparin-binding EGF-like growth factor as a target in intercellular regulation of epidermal basal cell growth by suprabasal retinoic acid receptors. EMBO J 18:1539-48.
Wells AD, Li XC, Li Y, Walsh MC, Zheng XX, Wu Z, Nunez G, Tang A, Sayegh M, Hancock WW, Strom TB, Turka LA. 1999Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance. Nat Med. 5:1303-7.
Zhu W, TomHon C, Mason M, Campbell T, Shelden E, Richards N, Goodman M, Gumucio DL.1999Analysis of linked human epsilon and gamma transgenes: effect of locus control region hypersensitive sites 2 and 3 or a distal YY1 mutation on stage-specific expression patterns. Blood. 93:3540-3549.
Brinkmeier ML, Gordon DF, Dowding JM, Saunders TL, Kendall SK, Sarapura VD, Wood WM, Ridgway EC, Camper SA.1998Cell-specific expression of the mouse glycoprotein hormone alpha-subunit gene requires multiple interacting DNA elements in transgenic mice and cultured cells. Mol Endocrinol. 12:622-33.
Burrows HL, Nakajima M, Lesh JS, Goosens KA, Samuelson LC, Inui A, Camper SA, Seasholtz AF. 1998Excess corticotropin releasing hormone-binding protein in the hypothalamic-pituitary-adrenal axis in transgenic mice. J. Clin. Invest. 101:1439-447.
Cunningham K, Ackerly H, Alt F, Dunnick W. 1998Potential regulatory elements for germline transcription in or near murine Sgamma1.Int Immunol. 10:527-536.
Cunningham K, Ackerly H, Claflin L, Collins J, Wu P, Ford C, Lansford R, Alt F, Dunnick WA.1998Germline transcription and recombination of a murine VDJmudeltagamma1 transgene. Int Immunol. 10:1027-1037.
Friis-Hansen, L, Sundler, F, Li, Y, Gillespie, PJ, Saunders, TL, Greenson, JK, Owyang, C, Rehfeld, JF, Samuelson, LC. 1998Impaired Gastric Acid Secretion in Gastrin-Deficient Mice. Am. J. Physiol. 274:G561-G568.
Kulig E, Camper SA, Kuecker S, Jin L, Lloyd RV. 1998Remodeling of Hyperplastic Pituitaries in Hypothyroid us-Subunit Knockout Mice After Thyroxine and 1713-Estradiol Treatment: Role of Apoptosis. Endocr Pathol. 9:261-274.
Lay JM, Friis-Hansen L, Gillespie PJ, Samuelson LC. 1998Rapid confirmation of gene targeting in embryonic stem cells using two long-range PCR techniques.Transgenic Res. 7:135-140.
Petschner, F, Zimmermann, C, Strasser, A, Grillot, D, Nunez, G, Pircher, H. 1998Constitutive expression of Bcl-x(L) or Bcl-2 prevents peptide antigen-induced T cell deletion but does not influence T cell homeostasis after a viral infection. Eur. J. Immunol. 28:560-569.
Pinson, KI, Dunbar, L, Samuelson, L, Gumucio, DL. 1998Targeted disruption of the mouse villin gene does not impair the morphogenesis of microvilli. Dev. Dyn. 211:109-121.
Probst FJ, Fridell RA, Raphael y, Saunders TL, Wang A, Liang Y, Morell RJ, Touchman JW, Lyons RH, Noben-Trauth K, Friedman TB, Camper SA. 1998Correction of Deafness in shaker-2 Mice by an Unconventional Myosin in a BAC Transgene.Science. 280:1444-1447.
WangA, Liang Y, Fridell RA, Probst FJ, Wilcox ER, Touchman JW, MortonCC, Morell RJ, Noben-Trauth K, Camper SA, Friedman TB. 1998Association of Unconventional Myosin MYO15 Mutations with Human Nonsyndromic Deafness DFNB3. Science. 280:1447 – 1451.
Solvason, N, Wu, WW, Kabra, N, Lund-Johansen, F, Roncarolo, MG, Behrens, TW, Grillot, DAM, Nunez, G, Lees, E, Howard, M. 1998Transgene expression of bcl-x(L) permits anti-immunoglobulin (Ig)-induced proliferation in xid B cells J. Exp. Med. 187: 1081-1091.
Wu P, Claflin L. 1998Promoter-associated displacement of hypermutations.Int Immunol. 10:1131-1138.
Yu RN, Ito M, Saunders TL, Camper SA, Jameson JL. 1998Role of Ahch in gonadal development and gametogenesis. Nat Genet 20:353-7.
Chamberlain, JS.1997Dystrophin levels required for genetic correction of Duchenne muscular dystrophy. Bas. Appl. Myol. 7:251-255.
Chamberlain, JS, Corrado, K, Rafael ,JA, Cox, GA, Hauser, M, Lumeng, C. 1997Interactions between dystrophin and the sarcolemma membrane. Soc Gen Physiol Ser 52:19-29.
Elenich, LA, Ford, CS, Collins, JT, Dunnick, WA. 1997gamma1 Heavy Chain Transgenes are Responsive to IFN-gamma Repression and CD40 Ligation. J. Immunol. 158:4564-4573.
Feng, X, Peng, ZH, Di, W, Li, XY, Rochette-Egly, C, Chambon, P, Voorhees, JJ, Xiao JH. 1997Suprabasal expression of a dominant-negative RXR alpha mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids. Genes Dev. 11:59-71.
Lowe JB.1997Selectin ligands, leukocyte trafficking, and fucosyltransferase genes. Kidney Int. 51:1418-1426.
Lynch, GS, Rafael, JA, Hinkle, RT, Cole, NM, Chamberlain, JS, Faulkner, JA. 1997Contractile properties of diaphragm muscle segments from old mdx and old transgenic mdx mice. Am. J. Phys-Cell Phys. 41:C2063-C2068.
Nelson, SA, Robins, DM. 1997Regulatory capacity of an androgen-specific enhancer of the mouse Slp gene in transgenic mice. Mol. Cell. Endo. 133:89-97.
Ohnishi, H, Samuelson, LC, Yule, DI, Ernst, SA, Williams, JA. 1997Overexpression of Rab3D enhances regulated amylase secretion from pancreatic acini of transgenic mice J Clin. Inv. 100:3044-3052.
Straub, V, Rafael, JA, Chamberlain, JS, Campbell, KP. 1997Animal models for muscular dystrophy show different patterns of sarcolemmal disruption. J. Cell. Biol. 139:375-385.
TomHon, C, Zhu, W, Millinoff, D, Hayasaka, K, Slightom, JL, Goodman, M, Gumucio, DL.1997Evolution of a fetal expression pattern via cis changes near the gamma globin gene. J. Biol. Chem. 272:14062-14066.
Burrows, HL, Birkmeier, TS, Seasholtz, AF, Camper, SA. 1996Targeted Ablation of Cells in the Pituitary Primordia of Transgenic Mice. Mol. Endo. 10:1467-1477.
Corrado, K, Rafael, JA, Mills, PL, Cole, NM, Faulkner, JA, Wang, K, Chamberlain, JS. 1996Transgenic mdx Mice Expressing Dystrophin with a Deletion in the Actin-Binding Domain Display a “Mild Becker” Phenotype. J. Cell Biology. 134:873-884.
Cui, J, O’Shea KS, Purkayastha A, Saunders TL, Ginsburg, D. 1996Fatal Haemorrhage and Incomplete Block to Embryogenesis in Mice Lacking Coagulation Factor V. Nature. 382:66-68.
Eitzman, DT, Krauss, JC, Shen, T, Cui, J, Ginsburg, D.1996Lack of plasminogen activator inhibitor-1 effect in a transgenic mouse model of metastatic melanoma. Blood. 87:4718-4722.
Eitzman, DT, McCoy, RD, Zheng, X, Fay, WP, Shen, T, Ginsburg, D, Simon, RH. 1996Bleomycin-Induced Pulmonary Fibrosis in Transgenic Mice that Either Lack or Overexpress the Murine Plasminogen Activator Inhibitor-1 Gene. J. Clin. Invest. 97:232-237.
Elenich, LA, Ford, CS, Dunnick, WA.1996The gamma 1 Heavy Chain Gene Includes all of the cis-Acting Elements Necessary for Expression of Properly Regulated Germ-Line Transcripts. J. Immunol. 157:176-182.
Grillot, DA, Merino, R, Pena, JC, Fanslow, WC, Finkelman, FD, Thompson, CB, Nunez, G. 1996bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice. J. Exp. Med. 183:381-391.
Maly P, Thall AD, Petryniak B, Rogers CE, Smith PL, Marks RM, Kelly RJ, Gersten KM, Cheng G, Saunders TL, Camper SA, Camphausen RT, Sullivan RX, Isogai Y, Hindsgaul O, von Andrian UH, Lowe JB.1996The alpha(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis. Cell. 86:643-653.
Rafael, JA, Cox, GA, Corrado, K, Jung, D, Campbell, KP, Chamberlain, JS. 1996Forced expression of dystrophin deletion constructs reveals structure-function correlations. J .Cell Biol. 134:93-102.
Samuelson, LC. 1996Transgenic approaches to salivary gland research. Ann. Rev. Phys. 58: 209-229.
Thall, AD, Murphy, HS, Lowe, JB. 1996alpha 1,3-Galactosyltransferase-deficient mice produce naturally occurring cytotoxic anti-Gal antibodies.Transplant. Proc. 28:556-557.
Tucker RM, Burke DT. 1996Transgenic mice for the establishment of histidinol-resistant embryonic fibroblast feeder layers.FASEB J. 10:1641-1645.
Camper, SA, Saunders, TL, Kendall, SK, Keri, RA, Seasholtz, AF, Gordon, DF, Birkmeier, TS, Keegan, CE, Karolyi, IJ, Roller, ML, Burrows, HL, Samuelson, LC. 1995Implementing transgenic and embryonic stem cell technology to study gene expression, cell-cell interactions and gene function. Biol. Reprod. 52:246-2457.
Chen C, Nagy Z, Radic MZ, Hardy RR, Huszar D, Camper SA, Weigert M. 1995The site and stage of anti-DNA B-cell deletion. Nature. 373:252-255.
Dunnick W Elenich L Cunningham K Chrisp C Claflin L.1995Tumorigenesis in mice with an SV40 T antigen transgene driven by the immunoglobulin gamma 1 heavy chain germline promoter. Curr. Top. Microbiol. Immunol. 194:163-169.
Grillot, DA, Merino, R, Nunez, G. 1995Bcl-XL Displays Restricted Distribution During T Cell Development and Inhibits Multiple Forms of Apoptosis but not Clonal Deletion in Transgenic Mice. J. Exp. Med. 182:1973-1983.
Kendall, SK, Samuelson, LC, Saunders, TL, Wood, RI, Camper, SA. 1995Targeted Disruption of the Pituitary Glycoprotein Hormone alpha-subunit Produces Hypogonadal and Hypothyroid Mice. Genes Dev. 9:2007-2019.
Phelps SF, Hauser MA, Cole NM, Rafael JA, Hinkle RT, Faulkner JA, Chamberlain JS. 1995Expression of full-length and truncated dystrophin mini-genes in transgenic mdx mice. Human Mol. Genet. 4:1251-1258.
Radic, MZ, Ibrahim, SM, Rauch, J, Camper, SA, Weigert, M. 1995Constitutive secretion of transgene-encoded IgG2b autoantibodies leads to symptoms of autoimmune disease. J. Immunol. 155:3213-3222.
Thall, AD, Maly, P, Lowe, JB. 1995Oocyte Gal-alpha1,3Gal Epitopes Implicated in Sperm Adhesion to the Zona Pellucida Glycoprotein ZP3 are not Required for Fertilization in the Mouse. J. Biol. Chem. 270:21437-21440.
Zheng, XX, Saunders, TL, Samuelson, LC, Camper, SA, Ginsburg, D. 1995Vitronectin is not Essential for Mammalian Development. Proc. Natl. Acad. Sci. U.S.A. 92:12326-12430.
Chen C, Radic MZ, Erikson J, Camper SA, Litwin S, Hardy RR, Weigert M, 1994Deletion and editing of B cells that express antibodies to DNA. J. Immunol. 152:1970-1982.
Chen EH, Mitchell BS. 1994Hereditary overexpression of adenosine deaminase in erythrocytes: studies in erythroid cell lines and transgenic mice. Blood. 84:2346-2353.
Denetclaw WF, Jr Hopf FW, Cox GA, Chamberlain JS, Steinhardt RA. 1994Myotubes from transgenic mdx mice expressing full-length dystrophin show normal calcium regulation. Mol. Biol. Cell. 5:1159-1167.
Cox GA, Sunada Y, Campbell KP, Chamberlain JS.1994Dp71 can restore the dystrophin-associated glycoprotein complex in muscle but fails to prevent dystrophy. Nat. Genet. 8:333-339.
Keegan, CE, Karolyi, IJ, Knapp, LT, Bourbonais, FJ, Camper, SA, Seasholtz, AF. 1994Expression of corticotropin-releasing hormone transgenes in neurons of adult and developing mice. Mol. Cell. Neurosci. 5:505-514.
Keri RA, Wolfe MW, Saunders TL, Anderson I Kendall SK Wagner T, Yeung J, Gorski J, Nett TM, Camper SA, Nilson, JH. 1994The proximal promoter of the bovine luteinizing hormone beta-subunit gene confers gonadotrope-specific expression and regulation by gonadotropin-releasing hormone, testosterone, and 17 beta-estradiol in transgenic mice. Mol. Endocrinol. 8:1807-1816.
Kendall SK, Gordon DF, Birkmeier TS, Petrey D, Sarapura VD, O’Shea KS, Wood WM, Lloyd RV, Ridgway EC, Camper SA.1994Enhancer-mediated high level expression of mouse pituitary glycoprotein hormone alpha-subunit transgene in thyrotropes, gonadotropes, and developing pituitary gland. Mol. Endocrinol. 8:1420-1433.
Rafael JA, Sunada Y, Cole NM, Campbell KP, Faulkner JA, Chamberlain JS. 1994Prevention of dystrophic pathology in mdx mice by a truncated dystrophin isoform. Hum. Mol. Genet. 3:1725-1733.
Cox GA, Cole NM, Matsumura K, Phelps SF, Hauschka, SD Campbell KP, Faulkner JA, Chamberlain JS.1993Overexpression of dystrophin in transgenic mdx mice eliminates dystrophic symptoms without toxicity. Nature 364:725-729.
Gay, D, Saunders, T, Camper, S, Weigert, M. 1993Receptor editing: an approach by autoreactive B cells to escape tolerance. J. Exp. Med. 177:999-1008.
Shlomchik, MJ, Zharhary, D, Saunders, T, Camper, SA, Weigert, MG.1993A rheumatoid factor transgenic mouse model of autoantibody regulation. Int. Immunol. 5:1329-1341.
Dunnick, W, Elenich, L, Berry, J, Albrecht, D, Stavnezer, J, Claflin, JL. 1992Regulation of switch recombination to the murine gamma 1 gene. Curr. Top. Microbiol. Immunol. 182:143-147.
Ting CN, Rosenberg MP, Snow CM, Samuelson LC, Meisler MH. 1992Endogenous retroviral sequences are required for tissue-specific expression of a human salivary amylase gene. Genes Dev. 6:1457-1465.
Carmack CE, Camper SA, Mackle JJ, Gerhard WU, Weigert MG.1991Influence of a V kappa 8 L chain transgene on endogenous rearrangements and the immune response to the HA(Sb) determinant on influenza virus. J. Immunol. 147:2024-2033.
Erikson J Radic MZ Camper SA Hardy RR Carmack C Weigert M.1991Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice. Nature. 349:331-334.
Kendall SK, Saunders TL, Jin L, Lloyd RV, Glode LM, Nett TM, Keri RA, Nilson JH, Camper SA. 1991Targeted ablation of pituitary gonadotropes in transgenic mice. Mol. Endocrinol. 5:2025-2036.
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