Per the latest University of Michigan Research Guidelines, laboratories and research spaces are now operating at a density capacity that safely allows for at least six feet of social distancing between personnel. For the latest Core updates, please visit the BRCF Research Reactivation Guidelines.

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Our Mission

We believe in serving you, advancing health, and paving the way for great discoveries in biomedical research at the University of Michigan and beyond.

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Core Facilities

Cores are centralized facilities or labs which offer shared services, shared equipment, resources and expertise to biomedical researchers and investigators on a fee-for-service basis.

Advanced Genomics

provides high-quality, low-cost DNA analysis for research clients on a recharge basis, including genotyping, gene expression analysis, DNA quantification and quality control


develops and applies computational tools and methods to biological or biomedical research data including acquisition, storage, organization, analysis, or visualization of data

Biomedical Research Store

provides easy, on-site procurement of more than 700 different items, including enzymes, reagents, and kits used in molecular, cell biology, and some protein chemistry


provides resources and services to prepare samples for analysis in epigenetic regulation in both genome-wide and locus-specific manners

Flow Cytometry

provides instrumentation and expertise in flow cytometric analysis and cell sorting


measures and analyzes concentrations of small molecules in biological samples, including targeted and untargeted assays. 


offers equipment for microscopic imaging, including fluorescence microscopy, as well as scanning and transmission electron microscopy

Proteomics & Peptide Synthesis

exceptional access to research services in peptide synthesis, qualitative and quantitative proteomics and protein analysis by mass spectrometry and other techniques

Transgenic Animal Model

produces transgenic mice and rats, CRISPR/Cas9 pipeline, mouse knockout models, ES cell lines, and BAC Recombineering


produces gene transfer vectors, using AAV, adenovirus, lentivirus, retrovirus, and plasmids, that facilitate the transfer of specific genes into either normal or aberrant cells


Standing Together Against Racism

Michigan Medicine leadership recently issued the statement that “we unequivocally recognize racism as a public health issue and we stand together against bias and inequality.”

Here at the Medical School Office of Research, we wholeheartedly endorse this message and the institutional strategy and actions required to take on and defeat racism. Michigan Medicine and the university are adding new tools and resources every day to foster culture change, and we encourage you to connect with the Michigan Medicine Office of Counseling and Workplace Resilience if you are struggling with issues of racism and how it impacts your personal and professional life.

Racism has no place in the Medical School Office of Research. As current events unfold across the country, and the fall-out of the pandemic continues to contribute to anxiety at both a personal and community level, we continue to be committed to nurturing an environment of compassion and inclusion that ultimately helps us fulfill our mission to support research and improve the lives of patients.

The Biomedical Research Store

Provides University of Michigan research investigators with easy, on-site procurement of enzymes, reagents, and kits used in molecular, cell biology, and some protein chemistry.

More than 700 different items from 13 vendors are stocked at five locations for immediate purchase.

Browse Stock Products


The Biosciences Initiative and Medical School Office of Research have partnered to create a powerful, searchable database with information on research cores across campus. The new Michigan Research Cores web portal now enables researchers to easily find and identify the location and capabilities of 70 research cores across campus. Visit the site to learn more!


  • Our Mission is Your Research

    Over the last two years, the BRCF Communication + Culture and Administrative teams have taken a closer look at what drives our work. Our teams held collaborative working sessions, conducted a department-wide survey to source feedback, and hosted small, internal …

  • AGC Data Delivery Changes in the Time of UM-RCP

    With the recent announcement of the University of Michigan Research Computing Package (UMRCP), the BRCF Advanced Genomics Core (AGC) has been working with Information and Technology Services (ITS) to update our data delivery strategy. The Michigan Medicine version of the …



  • Bioinformatics Core Virtual 3-Day Workshop: RNA-Seq Demystified

    This is a 3 x ½ day virtual, hands-on workshop targeted toward researchers who would like to be able to run RNA-Seq analysis on their own. Workshop Schedule: 11/15-11/17, 9:00 AM-1:00 PM ET: Hands-On RNA-Seq Analysis About the Workshop: This …

  • University of Michigan Multiome Webinar Series – Session 2

    Deep insights into tumor biology, developmental biology, and other biological processes and disease states require a comprehensive view of gene expression patterns and their corresponding epigenetic regulation at single-cell resolution. Leverage two modalities at once in single cells with Chromium …