Biomedical Research Core Facilities

Our Mission

We believe in serving you, advancing health, and paving the way for great discoveries in biomedical research at the University of Michigan and beyond.

Core Facilities

Cores are centralized facilities or labs which offer shared services, shared equipment, resources and expertise to biomedical researchers and investigators on a fee-for-service basis.

Advanced Genomics

provides high-quality, low-cost DNA analysis for research clients on a recharge basis, including genotyping, gene expression analysis, DNA quantification and quality control


develops and applies computational tools and methods to biological or biomedical research data including acquisition, storage, organization, analysis, or visualization of data

Biomedical Research Store

provides easy, on-site procurement of more than 700 different items, including enzymes, reagents, and kits used in molecular, cell biology, and some protein chemistry


provides resources and services to prepare samples for analysis in epigenetic regulation in both genome-wide and locus-specific manners

Flow Cytometry

provides instrumentation and expertise in flow cytometric analysis and cell sorting


measures and analyzes concentrations of small molecules in biological samples, including targeted and untargeted assays. 


offers equipment for microscopic imaging, including fluorescence microscopy, as well as scanning and transmission electron microscopy

Proteomics & Peptide Synthesis

provides research services in proteomics, protein analysis by mass spectrometry and other techniques, as well as custom peptide synthesis. The Core offers a full range of services in qualitative and quantitative proteomics, including the preparation of (unprocessed) clinical research samples as well as biological samples.

Proteomics Resource Facility

offers a wide-range of proteomic services in a highly cost-effective and timely manner

Biochemical Nuclear Magnetic Resource

provides support and consultation for experiments performed on state-of-the-art spectrometers

Transgenic Animal Model

produces transgenic mice and rats, CRISPR/Cas9 pipeline, mouse knockout models, ES cell lines, and BAC Recombineering


produces gene transfer vectors, using AAV, adenovirus, lentivirus, retrovirus, and plasmids, that facilitate the transfer of specific genes into either normal or aberrant cells


Standing Together Against Racism

Michigan Medicine leadership recently issued the statement that “we unequivocally recognize racism as a public health issue and we stand together against bias and inequality.”

Here at the Medical School Office of Research, we wholeheartedly endorse this message and the institutional strategy and actions required to take on and defeat racism. Michigan Medicine and the university are adding new tools and resources every day to foster culture change, and we encourage you to connect with the Michigan Medicine Office of Counseling and Workplace Resilience if you are struggling with issues of racism and how it impacts your personal and professional life.

Racism has no place in the Medical School Office of Research. As current events unfold across the country, and the fall-out of the pandemic continues to contribute to anxiety at both a personal and community level, we continue to be committed to nurturing an environment of compassion and inclusion that ultimately helps us fulfill our mission to support research and improve the lives of patients.

The Biomedical Research Store

Provides University of Michigan research investigators with easy, on-site procurement of enzymes, reagents, and kits used in molecular, cell biology, and some protein chemistry.

More than 700 different items from 13 vendors are stocked at five locations for immediate purchase.

Browse Stock Products


The Biosciences Initiative and Medical School Office of Research have partnered to create a powerful, searchable database with information on research cores across campus. The new Michigan Research Cores web portal now enables researchers to easily find and identify the location and capabilities of 70 research cores across campus. Visit the site to learn more!


  • The BRCF is Growing

    The BRCF and the Department of Pathology have come together to transition the Proteomics Resource Facility (PRF), led by Dr. Alexey Nesvizhskii, into the BRCF where it will continue to offer resources and services through the BRCF. The Proteomics Resource …

  • CRISPR/Cas9 Training Class Offered by TAMC, January 16 – 27, 2023

    The University of Michigan Transgenic Animal Model Core will offer the CRISPR/Cas9 and Mouse ES Cell Training Class from January 16 through January 27. In this two-week long hands-on session, trainees will design, build, and validate CRISPR/Cas9 reagents in mouse …



  • Proteomics Seminar

    Save the date! More details and registration will be provided soon. The Proteomics & Peptide Synthesis Core is excited to announce the next proteomics seminar, which will discuss new applications in proteomics for clinical research. The BRCF Proteomics & Peptide …

  • Lunch & Learn: Introducing Your New ZEISS LSM 980 with Airyscan 2

    Presented by Dr. Matt Curtis ZEISS Microscopy Midwest Product Application Specialist The BRCF Microscopy Facility and your local ZEISS team is pleased to invite you to join us in-person or online to learn about the new LSM 980 confocal system …

Translate »