Bioinformatics
CORE UPDATES:
The BRCF Bioinformatics Core staff is working remotely. We do not anticipate this affecting the overall capacity of the core nor will it impact the work on your project. While remote, we are happy to arrange touchpoints with you via phone or videoconference at your convenience. Please let us know if you have questions or concerns by contacting bioinformatics@umich.edu.
The Bioinformatics Core
helps researchers identify and interpret patterns in RNA and DNA by placing sequencing data into a biologically meaningful context. This encompasses assisting with experimental design, developing reproducible workflows, analyzing next-generation sequencing data, and supporting manuscript development/publication.
Our Process
Consultation
We offer an initial, free pre-analysis consultation to discuss the types of analysis and support bioinformatics can provide, in addition to assisting with experimental design to best answer the biological question(s) of interest.
Analysis
We provide analysis of high-throughput sequencing data, including RNA-Seq, ChIP-Seq, and Exome-Seq, as well as other high throughput data. We generate detailed project plans to outline analysis, implement reproducible workflows, generate visualizations of complex data, and assist data uploads to public repositories.
Follow Up Meeting
Following the delivery of results, we meet with researchers (faculty, staff, post-docs and graduate students) to answer follow-up questions.
*When requesting a consultation, please include key experimental details including data type (RNA, DNA, single-cell, etc.), species, the expected number of samples, and the timeline for sample submission in all requests.
Core Testimonials
“We are thrilled with the services provided to our team by the BRCF Bioinformatics Core, the services provide enabled us to publish top tier papers and be awarded multiple NIH funded grants. We are very grateful to have this Core available to us on campus!”
“I’ve greatly enjoyed my experience working with the Bioinformatics Core. Chris and his team were instrumental in establishing a workflow for the measurement of allele-specific expression using data from targeted RNA-seq and DNA-seq. Their services were timely and helped us to publish and secure continued funding.”
General Information
734-998-9249
Our People
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News
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The BRCF is Growing
The BRCF and the Department of Pathology have come together to transition the Proteomics Resource Facility (PRF), led by Dr. Alexey Nesvizhskii, into the BRCF where it will continue to offer resources and services through the BRCF. The Proteomics Resource …
Services Instrumentation Breaking News -
CRISPR/Cas9 Training Class Offered by TAMC, January 16 – 27, 2023
The University of Michigan Transgenic Animal Model Core will offer the CRISPR/Cas9 and Mouse ES Cell Training Class from January 16 through January 27. In this two-week long hands-on session, trainees will design, build, and validate CRISPR/Cas9 reagents in mouse …
Event Breaking News
Events
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Proteomics Seminar
Save the date! More details and registration will be provided soon. The Proteomics & Peptide Synthesis Core is excited to announce the next proteomics seminar, which will discuss new applications in proteomics for clinical research. The BRCF Proteomics & Peptide …
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Lunch & Learn: Introducing Your New ZEISS LSM 980 with Airyscan 2
Presented by Dr. Matt Curtis ZEISS Microscopy Midwest Product Application Specialist The BRCF Microscopy Facility and your local ZEISS team is pleased to invite you to join us in-person or online to learn about the new LSM 980 confocal system …
Event