Epigenomics
Updated 6/16/2020: As part of the Medical School Research Reactivation Process guidelines, the Epigenomics Core has been approved to reopen for labs and staff who conduct research within MSRB.
For the latest Epigenomics Core updates, including operating procedures and hours, please visit the BRCF Research Reactivation Guidelines.
The Epigenomics Core
provides resources and services to prepare samples for analysis in epigenetic regulation in both genome-wide and locus-specific manners. Epigenetic regulation refers to DNA sequence-independent regulation of heritable traits that impacts gene expression. In recent years the term has broadened to also encompass processes that control gene expression and genomic functions beyond DNA sequence but which may be more transient or facultative in nature.
Our Process
Project Initiation
Utilizing our new Consultation Request Form, the Investigator will submit a request for services with the Epigenomics Core.
Submit Samples
A member of the Epigenomics Core will schedule a consultation with the Investigator. After the consultation, the investigator will then send/deliver samples to our core for review.
Sample Processing
The Epigenomics Core will oversee the quality control of samples, providing assay-specific sample processing and library preparation. We will then submit samples/libraries to the Advanced Genomics Core for downstream processing.
Data Review
The Epigenomics Core will review the data from the Advanced Genomics Core providing data quality control, alignment, and analysis (if requested). The core will then return the data and reports to the investigator, completing the process cycle.
“From top-notch library preparation and sample quality controls to expert analysis, the Epigenomics Core strives to offer the best in epigenomics and bioinformatics resources.”
Claudia Lalancette, Ph.D.
Managing Director, Epigenomics Core
News
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Dr. Dolinoy Featured in Society of Toxicology’s new Adverse Reactions Podcast
Epigenetics expert Dana C. Dolinoy of the University of Michigan School of Public Health and Faculty Director for the BRCF Epigenomics Core illuminates how our nascent understanding of the epigenome is leading to breakthroughs in understanding the causes—and potential treatment—of some …
Staff Breaking News -
Standing Together Against Racism
Michigan Medicine leadership recently issued the statement that “we unequivocally recognize racism as a public health issue and we stand together against bias and inequality.” Here at the Medical School Office of Research, we wholeheartedly endorse this message and the …
Breaking News
Events
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An Update on NCBI BLAST and Other Sequence Analysis Tools
This workshop highlights new displays and features and introduces best practices for use of NCBI BLAST services. You will learn when and how to use important but often misunderstood aspects of the BLAST programs, specialized services, and databases. You will …
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Getting Started with NCBI Data in Python
Learn how to tackle bigger biomolecular datasets more reliably with the power of Python programming. This workshop is designed for biologists without programming experience OMB Control Number: 0925-0740 Expiration Date: 07/31/2022 Public reporting burden for this collection of information …
Event