Epigenomics
Updated 6/16/2020: As part of the Medical School Research Reactivation Process guidelines, the Epigenomics Core has been approved to reopen for labs and staff who conduct research within MSRB.
For the latest Epigenomics Core updates, including operating procedures and hours, please visit the BRCF Research Reactivation Guidelines.
The Epigenomics Core
provides resources and services to prepare samples for analysis in epigenetic regulation in both genome-wide and locus-specific manners. Epigenetic regulation refers to DNA sequence-independent regulation of heritable traits that impacts gene expression. In recent years the term has broadened to also encompass processes that control gene expression and genomic functions beyond DNA sequence but which may be more transient or facultative in nature.
Our Process
Project Initiation
Utilizing our new Consultation Request Form, the Investigator will submit a request for services with the Epigenomics Core.
Submit Samples
A member of the Epigenomics Core will schedule a consultation with the Investigator. After the consultation, the investigator will then send/deliver samples to our core for review.
Sample Processing
The Epigenomics Core will oversee the quality control of samples, providing assay-specific sample processing and library preparation. We will then submit samples/libraries to the Advanced Genomics Core for downstream processing.
Data Review
The Epigenomics Core will review the data from the Advanced Genomics Core providing data quality control, alignment, and analysis (if requested). The core will then return the data and reports to the investigator, completing the process cycle.
“From top-notch library preparation and sample quality controls to expert analysis, the Epigenomics Core strives to offer the best in epigenomics and bioinformatics resources.”
Claudia Lalancette, Ph.D.
Managing Director, Epigenomics Core
News
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Flow Cytometry Core Updates
Greetings Customers, We hope that each of you is doing well and staying safe. I am reaching out today with some important updates to share from our Flow Cytometry Core. New Equipment Kiosk System Coming in March We are excited …
Services Instrumentation Breaking News -
Important Updates from the Microscopy Core
Greetings Microscopy Core Users, We hope that you are doing well and happy new year to you. Since we last spoke, the Microscopy Core has experienced a few changes so we wanted to reach out with some important updates. A …
Services Breaking News
Events
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Getting Started with Single Cell Multiomics: Simultaneous Epigenomic and Transcriptomic Profiling from the Same Cell
Presented by 10x Genomics and University of Michigan Advanced Genomics Core Deep insights into tumor biology, developmental biology, and other biological processes and disease states require a comprehensive view of gene expression patterns and their corresponding epigenetic regulation at single …
Event