Updated 6/16/2020: As part of the Medical School Research Reactivation Process guidelines, the Epigenomics Core has been approved to reopen for labs and staff who conduct research within MSRB.
For the latest Epigenomics Core updates, including operating procedures and hours, please visit the BRCF Research Reactivation Guidelines.
The Epigenomics Core
provides resources and services to prepare samples for analysis in epigenetic regulation in both genome-wide and locus-specific manners. Epigenetic regulation refers to DNA sequence-independent regulation of heritable traits that impacts gene expression. In recent years the term has broadened to also encompass processes that control gene expression and genomic functions beyond DNA sequence but which may be more transient or facultative in nature.
Utilizing our new Consultation Request Form, the Investigator will submit a request for services with the Epigenomics Core.
A member of the Epigenomics Core will schedule a consultation with the Investigator. After the consultation, the investigator will then send/deliver samples to our core for review.
The Epigenomics Core will oversee the quality control of samples, providing assay-specific sample processing and library preparation. We will then submit samples/libraries to the Advanced Genomics Core for downstream processing.
The Epigenomics Core will review the data from the Advanced Genomics Core providing data quality control, alignment, and analysis (if requested). The core will then return the data and reports to the investigator, completing the process cycle.
“From top-notch library preparation and sample quality controls to expert analysis, the Epigenomics Core strives to offer the best in epigenomics and bioinformatics resources.”
Claudia Lalancette, Ph.D.
Managing Director, Epigenomics Core
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