Metabolomics


Updated 6/16/2020: As part of the Medical School Research Reactivation Process guidelines, the Metabolomics Core has been approved to reopen for labs and staff who conduct research at Brehm. The Core is currently open select hours on Tuesday’s and Wednesday’s for customer pick-ups and drop-offs.

For the latest Metabolomics Core updates, including operating procedures and hours, please visit the BRCF Research Reactivation Guidelines.

The Metabolomics Core:

measures concentrations of small molecules in biological samples on a recharge basis. We strive to provide GLP-quality analytical services at competitive prices, and regularly customize assays to fit our clients’ needs. Services include initial consultation, method development, data collection, interpretation, and presentation. Core competencies include both targeted assays for many analyte classes as well as untargeted assays to evaluate the entire metabolome in biofluids and tissues, measurement of flux through various pathways using 13C-isotopomer analyses, and structural identification of isolated unknowns and potential biomarkers.

Our Process

Getting Started with the Core

The process for initiating a project with the Metabolomics Core varies depending on your institutional affiliation. Please review our guidelines and forms. Once the necessary steps are completed, your request will be reviewed. A consultation will be scheduled to review the project/experimental design with you and to provide a quote.

Request Services in MiCores

Please login to MiCores in order to schedule a consultation or request a service in the Core.

Submit Your Samples

For general guidelines in sample collection for metabolomics studies and specific instructions on how to submit your samples, please contact our core to download these important documents.

Request Project
What We Do
Research Consultation
  • Provide researchers assistance in the design and execution of experiments requiring the identification and quantification of metabolites.
  • Provide support for the analysis of spectral output data.
  • Provide statistical support through consultation, collaboration, and online tools.
Technology
  • Provide gas and liquid chromatography coupled with mass spectrometry (GC and LC MS) and nuclear magnetic resonance (NMR) based metabolomic analysis.
  • Provide tools for the normalization and quantification of identified and unidentified metabolites.
  • Provide bioinformatics tools to access information about metabolites, to visually analyze systems-level relationships between metabolites and ’omics data.
Training and Grants
  • Provide a variety of educational opportunities for students, fellows, and faculty in the field of metabolomics research.
  • Provide small and larger Pilot/Feasibility (P/F) grants to stimulate innovative efforts to incorporate metabolomics into basic, translational, and clinical research protocols.
Data Sharing
General Information

734-232-0842

Our People

Contact a Specific Staff Member

Email Us

mkachman@umich.edu

Our Locations:

6120 Brehm Tower, 1000 Wall Street, Ann Arbor, Michigan

Get Detailed Directions

News

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