Metabolomics
The Metabolomics Core:
measures concentrations of small molecules in biological samples on a recharge basis. We strive to provide GLP-quality analytical services at competitive prices, and regularly customize assays to fit our clients’ needs. Services include initial consultation, method development, data collection, interpretation, and presentation. Core competencies include both targeted assays for many analyte classes as well as untargeted assays to evaluate the entire metabolome in biofluids and tissues, measurement of flux through various pathways using 13C-isotopomer analyses, and structural identification of isolated unknowns and potential biomarkers.
Our Process
Getting Started with the Core
The process for initiating a project with the Metabolomics Core varies depending on your institutional affiliation. Please review our guidelines and forms. Once the necessary steps are completed, your request will be reviewed. A consultation will be scheduled to review the project/experimental design with you and to provide a quote.
Request Services in MiCores
Please login to MiCores in order to schedule a consultation or request a service in the Core.
Submit Your Samples
For general guidelines in sample collection for metabolomics studies and specific instructions on how to submit your samples, please contact our core to download these important documents.
What We Do
Research Consultation
- Provide researchers assistance in the design and execution of experiments requiring the identification and quantification of metabolites.
- Provide support for the analysis of spectral output data.
- Provide statistical support through consultation, collaboration, and online tools.
Technology
- Provide gas and liquid chromatography coupled with mass spectrometry (GC and LC MS) and nuclear magnetic resonance (NMR) based metabolomic analysis.
- Provide tools for the normalization and quantification of identified and unidentified metabolites.
- Provide bioinformatics tools to access information about metabolites, to visually analyze systems-level relationships between metabolites and ’omics data.
Training and Grants
- Provide a variety of educational opportunities for students, fellows, and faculty in the field of metabolomics research.
- Provide small and larger Pilot/Feasibility (P/F) grants to stimulate innovative efforts to incorporate metabolomics into basic, translational, and clinical research protocols.
Data Sharing
- Work with other Regional Comprehensive Metabolomics Resource Cores (RCMRC)s and the Metabolomics Consortium Data Repository and Coordinating Center (DRCC) to develop standard protocols for metabolomic data annotation, storage, and dissemination.
General Information
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Our People
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News
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The BRCF is Growing
The BRCF and the Department of Pathology have come together to transition the Proteomics Resource Facility (PRF), led by Dr. Alexey Nesvizhskii, into the BRCF where it will continue to offer resources and services through the BRCF. The Proteomics Resource …
Services Instrumentation Breaking News -
CRISPR/Cas9 Training Class Offered by TAMC, January 16 – 27, 2023
The University of Michigan Transgenic Animal Model Core will offer the CRISPR/Cas9 and Mouse ES Cell Training Class from January 16 through January 27. In this two-week long hands-on session, trainees will design, build, and validate CRISPR/Cas9 reagents in mouse …
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Events
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Proteomics Seminar
Save the date! More details and registration will be provided soon. The Proteomics & Peptide Synthesis Core is excited to announce the next proteomics seminar, which will discuss new applications in proteomics for clinical research. The BRCF Proteomics & Peptide …
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