Metabolomics Publications
- 18F-Choline PET/MRI: The Additional Value of PET for MRI-Guided Transrectal Prostate Biopsies.. J Nucl Med. PubMed . 2016.
- 1D-¹H-nuclear magnetic resonance metabolomics reveals age-related changes in metabolites associated with experimental venous thrombosis.. J Vasc Surg Venous Lymphat Disord. 4(2):221-30. PubMed . 2016.
- Adrenal-derived 11-oxygenated 19-carbon steroids are the dominant androgens in classic 21-hydroxylase deficiency.. Eur J Endocrinol. 174(5):601-9. PubMed . 2016.
- Altered fecal short chain fatty acid composition in children with a history of Hirschsprung-associated enterocolitis.. J Pediatr Surg. 51(1):81-6. PubMed . 2016.
- Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer.. Cell. 165(5):1092-105. PubMed . 2016.
- Evaluation of coverage, retention patterns, and selectivity of seven liquid chromatographic methods for metabolomics.. Anal Bioanal Chem. 408(22):6079-91. PubMed . 2016.
- Extraction, Enrichment, Solubilization, and Digestion Techniques for Membrane Proteomics.. J Proteome Res. 15(4):1243-52. PubMed . 2016.
- Greazy: Open-Source Software for Automated Phospholipid Tandem Mass Spectrometry Identification.. Anal Chem. 88(11):5733-41. PubMed . 2016.
- Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease.. Nat Immunol. 17(5):505-13. PubMed . 2016.
- Impaired 17,20-Lyase Activity in Male Mice Lacking Cytochrome b5 in Leydig Cells.. Mol Endocrinol. 30(4):469-78. PubMed . 2016.
- Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools.. Nucleic Acids Res. 44(D1):D463-70. PubMed . 2016.
- Oxidative Modifications of Protein Tyrosyl Residues Are Increased in Plasma of Human Subjects with Interstitial Lung Disease.. Am J Respir Crit Care Med. 193(8):861-8. PubMed . 2016.
- Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.. Nature. 536(7617):479-83. PubMed . 2016.
- Purinergic dysregulation in pulmonary hypertension.. Am J Physiol Heart Circ Physiol. :ajpheart.00572.2015. PubMed . 2016.
- RhoC is a Potent Regulator of Glutamine Metabolism and N-acetylaspartate Production in Inflammatory Breast Cancer Cells.. J Biol Chem. PubMed . 2016.
- Adipose fatty acid oxidation is required for thermogenesis and potentiates oxidative stress-induced inflammation.. Cell Rep. 10(2):266-79. PubMed . 2015.
- Altered Metabolic Profile With Sodium-Restricted Dietary Approaches to Stop Hypertension Diet in Hypertensive Heart Failure With Preserved Ejection Fraction.. J Card Fail. 21(12):963-7. PubMed . 2015.
- AMPK Protects Leukemia-Initiating Cells in Myeloid Leukemias from Metabolic Stress in the Bone Marrow.. Cell Stem Cell. 17(5):585-96. PubMed . 2015.
- The balance of powers: Redox regulation of fibrogenic pathways in kidney injury.. Redox Biol. 6:495-504. PubMed . 2015.
- Catecholamine-resistant hypotension and myocardial performance following patent ductus arteriosus ligation.. J Perinatol. 35(2):123-7. PubMed . 2015.
- Chronic Zinc Deficiency Alters Chick Gut Microbiota Composition and Function.. Nutrients. 7(12):9768-84. PubMed . 2015.
- Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease.. Arthritis Rheumatol. 67(1):128-39. PubMed . 2015.
- Developmental programming: exposure to testosterone excess disrupts steroidal and metabolic environment in pregnant sheep.. Endocrinology. 156(6):2323-37. PubMed . 2015.
- DIA-Umpire: comprehensive computational framework for data-independent acquisition proteomics.. Nat Methods. 12(3):258-64,7pfollowing264. PubMed . 2015.
- Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome..Nature. 519(7541):92-6. PubMed . 2015.
- A Diet-Sensitive BAF60a-Mediated Pathway Links Hepatic Bile Acid Metabolism to Cholesterol Absorption and Atherosclerosis.. Cell Rep. 13(8):1658-69. PubMed . 2015.
- Dynamics and establishment of Clostridium difficile infection in the murine gastrointestinal tract.. Infect Immun. 83(3):934-41. PubMed . 2015.
- Evidence for a link between gut microbiota and hypertension in the Dahl rat.. Physiol Genomics. 47(6):187-97. PubMed . 2015.
- FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization.. Nat Commun. 6:7079. PubMed . 2015.
- Gene expression changes in subcutaneous adipose tissue due to Cushing’s disease.. J Mol Endocrinol. 55(2):81-94. PubMed . 2015.
- Gene Expression Signature in Adipose Tissue of Acromegaly Patients.. PLoS One. 10(6):e0129359. PubMed . 2015.
- Impact of anesthesia and euthanasia on metabolomics of mammalian tissues: studies in a C57BL/6J mouse model.. PLoS One. 10(2):e0117232. PubMed . 2015.
- Impact of gestational bisphenol A on oxidative stress and free fatty acids: Human association and interspecies animal testing studies.. Endocrinology. 156(3):911-22. PubMed . 2015.
- Impact of storage conditions on metabolite profiles of sputum samples from persons with cystic fibrosis.. J Cyst Fibros. 14(4):468-73. PubMed . 2015.
- Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by ferulic acid decarboxylase and 4-hydroxy-3-polyprenylbenzoic acid decarboxylase.. ACS Chem Biol. 10(4):1137-44. PubMed . 2015.
- The macrophage phagocytic receptor CD36 promotes fibrogenic pathways on removal of apoptotic cells during chronic kidney injury.. Am J Pathol. 185(8):2232-45. PubMed . 2015.
- Maximal oxidative capacity during exercise is associated with skeletal muscle fuel selection and dynamic changes in mitochondrial protein acetylation.. Cell Metab. 21(3):468-78. PubMed . 2015.
- Melatonin prevents myeloperoxidase heme destruction and the generation of free iron mediated by self-generated hypochlorous acid.. PLoS One. 10(3):e0120737. PubMed . 2015.
- Metabolomic Profiling of Arginine Metabolome Links Altered Methylation to Chronic Kidney Disease Accelerated Atherosclerosis.. J Proteomics Bioinform. Suppl 14 PubMed . 2015.
- Metabolomics Analysis Reveals that AICAR Affects Glycerolipid, Ceramide and Nucleotide Synthesis Pathways in INS-1 Cells..PLoS One. 10(6):e0129029. PubMed . 2015.
- Metabolomics and diabetes: analytical and computational approaches.. Diabetes. 64(3):718-32. PubMed . 2015.
- Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production.. J Clin Invest. 125(10):3819-30. PubMed . 2015.
- Pharmacometabolomics of l-carnitine treatment response phenotypes in patients with septic shock.. Ann Am Thorac Soc. 12(1):46-56. PubMed . 2015.
- Plasma linoleic acid partially mediates the association of bipolar disorder on self-reported mental health scales.. J Psychiatr Res. 68:61-7. PubMed . 2015.
- PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.. Cell. 161(6):1293-305. PubMed . 2015.
- Profiles of 21-Carbon Steroids in 21-hydroxylase Deficiency.. J Clin Endocrinol Metab. 100(6):2283-90. PubMed . 2015.
- Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response.. Elife. 4:e10067. PubMed . 2015.
- Reemergence of hedgehog mediates epithelial-mesenchymal crosstalk in pulmonary fibrosis.. Am J Respir Cell Mol Biol. 52(4):418-28. PubMed . 2015.
- Serum Cortisol-to-Cortisone Ratio and Blood Pressure in Severe Obesity before and after Weight Loss..Cardiorenal Med. 6(1):1-7. PubMed . 2015.
- Targeted Lipidomic and Transcriptomic Analysis Identifies Dysregulated Renal Ceramide Metabolism in a Mouse Model of Diabetic Kidney Disease.. J Proteomics Bioinform. Suppl 14. PubMed
The ubiquitin ligase Siah2 regulates obesity-induced adipose tissue inflammation.. Obesity (Silver Spring). 23(11):2223-32. PubMed
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- Administration of saccharin to neonatal mice influences body composition of adult males and reduces body weight of females.. Endocrinology. 155(4):1313-26. PubMed . 2014.
- Alteration of the murine gastrointestinal microbiota by tigecycline leads to increased susceptibility to Clostridium difficile infection.. Antimicrob Agents Chemother. 58(5):2767-74. PubMed . 2014.
- Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection.. Nat Commun. 5:3114. PubMed . 2014.
- Continuous 24-hour leptin, proopiomelanocortin, and amino acid measurements in human cerebrospinal fluid: correlations with plasma leptin, soluble leptin receptor, and amino acid levels.. J Clin Endocrinol Metab. 99(7):2540-8. PubMed . 2014.
- Diet and feeding pattern affect the diurnal dynamics of the gut microbiome.. Cell Metab. 20(6):1006-17. PubMed . 2014.
- Disruption of heme-peptide covalent cross-linking in mammalian peroxidases by hypochlorous acid.. J Inorg Biochem. 140:245-54. PubMed . 2014.
- Establishing 3-nitrotyrosine as a biomarker for the vasculopathy of Fabry disease..Kidney Int. 86(1):58-66. PubMed . 2014.
- Hypotension following patent ductus arteriosus ligation: the role of adrenal hormones.. J Pediatr. 164(6):1449-55.e1. PubMed . 2014.
- Increased glucose metabolism and glycerolipid formation by fatty acids and GPR40 receptor signaling underlies the fatty acid potentiation of insulin secretion.. J Biol Chem. 289(19):13575-88. PubMed . 2014.
- Long-chain acyl coenzyme A synthetase 1 overexpression in primary cultured Schwann cells prevents long chain fatty acid-induced oxidative stress and mitochondrial dysfunction.. Antioxid Redox Signal. 21(4):588-600. PubMed . 2014.
- Metabolic network motifs can provide novel insights into evolution: The evolutionary origin of Eukaryotic organelles as a case study.. Comput Biol Chem. 53PB:242-250. PubMed . 2014.
- MetDisease–connecting metabolites to diseases via literature.. Bioinformatics. 30(15):2239-41. PubMed . 2014.
- Microbiota, oral microbiome, and pancreatic cancer.. Cancer J. 20(3):203-6. PubMed . 2014.
- A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels.. Cell Rep. 7(3):907-17. PubMed . 2014.
- mTORC1-independent reduction of retinal protein synthesis in type 1 diabetes..Diabetes. 63(9):3077-90. PubMed . 2014.
- Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: an additional proatherogenic mechanism in systemic lupus erythematosus.. Arthritis Rheumatol. 66(9):2532-44. PubMed . 2014.
- Testing the role of myeloid cell glucose flux in inflammation and atherosclerosis.. Cell Rep. 7(2):356-65. PubMed . 2014.
- Tryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathology.. J Immunol. 193(2):807-16. PubMed . 2014.
- Untargeted LC-MS metabolomics of bronchoalveolar lavage fluid differentiates acute respiratory distress syndrome from health.. J Proteome Res. 13(2):640-9. PubMed . 2014.
- Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study.. Kidney Int. 85(5):1214-24. PubMed . 2014.
- Artificial sweeteners stimulate adipogenesis and suppress lipolysis independently of sweet taste receptors.. J Biol Chem. 288(45):32475-89. PubMed . 2013.
- Cortisol response to operative stress with anesthesia in healthy children.. J Clin Endocrinol Metab. 98(9):3687-93. PubMed . 2013.
- Decreased glycolytic and tricarboxylic acid cycle intermediates coincide with peripheral nervous system oxidative stress in a murine model of type 2 diabetes.. J Endocrinol. 216(1):1-11. PubMed . 2013.
- High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis.. Ann Rheum Dis. 72(10):1725-31. PubMed . 2013.
- HR-MAS NMR tissue metabolomic signatures cross-validated by mass spectrometry distinguish bladder cancer from benign disease.. J Proteome Res. 12(7):3519-28. PubMed . 2013.
- Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma.. Blood. 122(6):958-68. PubMed . 2013.
- Mass spectrometry theory and application to adrenal diseases.. Mol Cell Endocrinol. 371(1-2):201-7. PubMed . 2013.
- Metabolome response to glucose in the β-cell line INS-1 832/13.. J Biol Chem. 288(15):10923-35. PubMed . 2013.
- Network motifs provide signatures that characterize metabolism.. Mol Biosyst. 9(3):352-60. PubMed . 2013.
- Profiling targets of the irreversible palmitoylation inhibitor 2-bromopalmitate.. ACS Chem Biol. 8(9):1912-7. PubMed . 2013.
- ZBP-89 regulates expression of tryptophan hydroxylase I and mucosal defense against Salmonella typhimurium in mice.. Gastroenterology. 144(7):1466-77,1477.e1-9. PubMed . 2013.
- Association of plasma ω-3 and ω-6 lipids with burden of disease measures in bipolar subjects.. J Psychiatr Res. 46(11):1435-41. PubMed . 2012.
- A short-term diet and exercise intervention ameliorates inflammation and markers of metabolic health in overweight/obese children.. Am J Physiol Endocrinol Metab. 303(4):E542-50. PubMed . 2012.