Publications & Expertise

Scientific expertise available at this Core

The Core director Dr. Remmer has 24 years of experience directing a Proteomics & Peptide Synthesis Core. Her scientific expertise in these areas is backed by years of research experience, including postdoctoral training in academia and industry.


Peer-Reviewed Journals and Publications

    1. E. Giuliani, SB Schon, K.Yang, GW Burns, LM. Neff, HA .Remmer, JA. Teixera, EE. Marsh. Obesity-induced follicular phase endometrial proteome dysregulation in a well-phenotyped population. FS Sci 2022 Nov; 3(4):367-375 PMID: 3570094
    2. D. Tyrrell, J. Chen, B. Li, S. Wood, W. Rosebury-Smith, H. Remmer, L. Jiang, M. Zhang, M. Salmon, G. Ailawadi, B. Yang, and D. Goldstein. Aging alters the aortic proteome from health to thoracic aortic aneurysm.2. D. Tyrrell, J. Chen, B. Li, S. Wood, W. Rosebury-Smith, H. Remmer, L. Jiang, M. Zhang, M. Salmon, G. Ailawadi, B. Yang, and D. Goldstein. Aging alters the aortic proteome from health to thoracic aortic aneurysm.Aterioskler Thromb Vasc Biol 2022, Aug 42(8): 1060-1076; PMID: 35510553
    3. G. Pornoppadol, B. Zhang, AA. Desai, A. Berardi, HA Remmer, PM.Tessier, CF. Greineder.  A hybridoma-derived monoclonal antibody with high homology to the aberrant myeloma light chain. PLOS One , Oct 2021, 11:16 (10), PMID: 3463404
    4. BE Biesterveld, AZ Siddiqui, RL. O’Connell, H Remmer, AM. Williams, A. Shamshad, WM. Smith, MT.Kemp, GK. Wakam, HB. Alam. Valproic acid protects against acute kidney injury in hemorrhage and trauma. J. Surg. Res. 2021, Oct 226:222-229, PMID: 34023578
    5. BE Biesterveld, L Pumiglia, A Iancu, AA Shamshad, HA Remmer, AZ Siddiqui,  RL O’Connell, MT Kemp, GK Wakam, HB Alam. Valproic acid treatment rescues injured tissues after traumatic brain injury. J. Trauma Acute Care Surg. 2020, Dec; 89 (6): 1156-1165. PMID: 32890344
    6. UF Bhatti, H. Remmer, A. Williams, BE. Biesterveld, R. Russo, G. Wakam, M. Kemp, R. Tagett, B. Liu, Y. Li, HB. Alam. Assessment of the Cytoprotective Effects of High-Dose Valproic Acid Compared to a Clinically Used Lower Dose. J. Surg. Res. Oct 2021, 266: 125-141. PMID: 33991999
    7. R. Ohara, G. Edhayan, S. Rasmussen, T. Isozaki, H. Remmer, T. Lanigan, PL. Campbell, A. Urquhart, J. Lawton, K. Chung, D. Fox, J. Ruth. 2019. Citrullinated Inhibitor of DNA Binding 1 is a Novel Autoantigen in Rheumatoid Arthritis. Arthritis Rheumatol. Mar 12, doi: 10.1002/art.40886 (epub ahead of print), PMID: 30861322
    8. S. Gadwal, TL. Johnson, HA. Remmer, M. Sandkvist. C-terminal processing of Gly-Gly CTERM containing peptides by rhombosortase in vobrio cholerae. PLOS Pathogens, accepted for publication.
    9. M. Weykamp, VC. Nikolian, IS. Dennahy, GA Higgins, PE Georgoff, H. Remmer, MH. Ghandour, HB. Alam. 2018. Rapid valproic-acid induced modulation of the traumatic proteome in a porcine model of traumatic brain injury and hemorrhagic shock. J. of Surgical Research 228 (Aug 2018), 84-92. PMID: 29907235
    10. P. Georgoff, I. Halaweish, V. Nikolian, T. Bonham, H. Remmer, R. Menon, B. Liu, Y. Li, HB. Alam. Alterations in the human proteome following administration of valproic acid. 2016. J. Trauma and Acute Care Surgery, accepted for publication.
    11. WR. Swindell, HA. Remmer, MK. Sarker, X. Xing, DH. Barnes, L. Wolterink, JJ. Vorhees, RP. Nair, A. Johnston, JT. Elder, JE. Gudjonsson. Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance.2015. Genome Med. Aug 4;7 (1):86. Doi: 10.1186/s13073-015-0208-5.e Collection 2015.
    12. LL. Kubik, RW. Landis, HA Remmer, IL. Bergin, MA. Philbert. 2015. 1,3-dinitrobenzene induces age-and region-specific oxidation to mitochondria –related proteins in brain. Toxicol. Sci. May; 145(1): 48:58. Doi:10.1093/toxsci/kfv015.PMID: 25716674
    13. Y Li, W Xia, Y Liu, HA Remmer, J Vorhees, GJ Fisher. Solar ultraviolet irridation induces decorin degradation in human skin likely via neutrophile elastase
    14. MP. Mendez, SB. Morris, S. Wicoxen, M. Du, YK. Monroy, H. Remmer, H. Murphy, PJ.  Christensen. R. Paine III. 2008. Disparate Mechanisms of sICAM-1 production in the peripheral lung: contrast between alveolar epithelial cells and pulmonary microvascular endothelial cells. Am. J. Lung Cell Mol. Physiol. 294, L807-L814. doi: 10.1152/ ajplung. 00389.2007
    15. I.J. Goldstein, H.C. Winter, L. Confer, J.T. Adamson, K. Hakansson, H.A. Remmer 2007.A new a-galactosyl-binding protein from mushroom Lyophyllum decastes. Arch. Biochem. Biophys. 467, 268-274. doi: 10.1016/
    16. Z.Zhang, H.A. Remmer, D.D.Thomas and C.B. Karim. 2006. Backbone Dynamics Determined by Electron Paramagnetic Resonance to Optimize Solid Phase Peptide Synthesis of TOAC-labeled Phospholamban. Biopolymers Peptide Science, 88 (1) p.29-35. doi: 10.1002/bip.20618.
    17. H.A. Remmer, N.P. Ambulos, L.F. Bonewald, J.D. Dougherty, E. Eisenstein, E. Fowler, J. Johnson, A. Khatri, M.O. Lively, N.M. Ritter, and S. Weintraub.2004. Synthetic Peptides as Certified Analytical Standards, in Peptide Revolution:  Genomics, Proteomics and Therapeutics (M Chorev and TK. Sawyer, eds), Kluwer Academic Publishers, p. 65-66.
    18. M.M.Rosenblatt, D.L. Huffman, X. Wang, H.A.Remmer & K.S. Suslick. 2002. Cyclic and Hairpin Peptide Complexes of Heme. J. Am. Chem. Soc. 124, 12394-12395.
    19. K. F.Medzihradszky, N. P. Ambulos, A. Khatri, G. Osapay, H.A. Remmer, A. Somogyi, and S. A. Kates.2002. Mass spectrometry analysis for the determination of side reactions for cyclic peptides prepared from an Fmoc/tBu/Dmab Protecting Group Strategy. Lett. Peptide Sci  8,1-12.
    20. Khatri, N.P. Amboulos, S.A. Kates, K.F. Medzihradszky, G. Ösapay, H.A. Remmer and A. Sompgyi  Strategies for the synthesis of cyclic peptides. 2001. Peptides: The wave of the future  (M Lebl and RA Houghton,eds) Kluwer Academic Publishers, p 140-141.
    21. H.A. Remmer_The Peptide Standards Project Committee. 2001. J. Biomoecular  Techniques 12, 3,72-73.
    22. H.A. Remmer_and G.B. Fields. 1999. Problems encountered with the synthesis of a glycosylated hydroxylysine derivative suitable for Fmoc-solid phase peptide synthesis. In: Peptides: Frontiers of Peptide Science (J.PTam and P.T.P. Kaumaya, eds), Kluwer Academic Publishers, 287-288.
    23. H.A. Remmer, E. Jaeger, G.Jung, P. Ruecknagel, T. Abdel-Razek and S.I. Said “Structure Activity Studies on VIP III: Synthesis and properties of [Ser(SO3H)3, Ahx17]VIP, [Ahx17]PACAP-27 and the VIP-PACAP-Hybrid  [Ahx17, Ala24, Ala25, Val26]VIP-(1-27)-amide” in: Peptides 1994 (HLS Maia, ed) p. 367-368;  Escom 1995
    24. H.A. Remmer, E. Jaeger, P. Ruecknagel & G. Jung. 1994. Comparison of Fmoc-solid phase methods for the synthesis of pure [Nle17] VIP. In: Innovation and Perspectives in Solid Phase Synthesis: Peptides, Proteins and Nucleic Acids Biomedical Applications (R. Epton, ed.) Mayflower Worldwide, Birmingham (1994) p. 657-660.
    25. E. Jaeger, H.A. Remmer, G. Jung, J. Metzger, W. Oberthuer, K.P. Ruecknagel, W. Schaefer, J. Sonnenbichler & I. Zetl. 1993. Side reactions in peptide synthesis V: “O-Sulfonation of Serine and Threonine during removal of the Pmc- and Mtr-protecting groups from arginine residues in Fmoc solid phase synthesis” Biol. Chem. Hoppe-Seyler, 374 ,349-362.
    26. E. Jaeger, P. Ruecknagel, H.A.Remmer & G. Jung. 1993. Synthesis and properties of peptides containing O-sulfonated serine and threonine residues.1993.  in Chemistry of Peptides and Proteins Vol. 5/6 (D. Brandenburg, V. Ivanov & W. Voelter, eds.), DWI Reports, Vol. 112A, Verlag Mainz, Aachen, 115-124.
    27. E. Jaeger, G. Jung, H.A. Remmer & P. Ruecknagel“ Formation of amino acid O-sulfonates during removal of the Pmc-group from Arginine residues in SPPS” in: Peptides, Chemistry and Biology (J.A. Smith & J. Rivier, eds.), p. 629-630,  Escom Scientific Publishers 1992.
    28. E. Jaeger, N. Veretennikova, H.A. Remmer & P. Ruecknagel “Synthetic studies on Tuftsin, VIP and gastrin analogs using Fmoc-amino acid-N-carboxyanhydrides in SPPS” in: Peptides 1992 (C.H. Schneider & A.N. Eberle, eds.) p. 226-228; Escom Science Publishers, 1992.
    29. E. Jaeger, H.A. Remmer, P. Thamm, S.I. Said & H. Sharaf . 1992. Structure activity studies on Vasoactive intestinal peptide: synthesis of analogs modified at residues Asp3-Ala4 and Asn9. Regulatory Peptides 40, 175.
    30. H.A. Remmer, G. Jung, P. Ruecknagel &  E. Jaeger “Facile formation of 2,3-didehydroalanine and 2,3-didehydrobutyrine in peptides containing O-sulfonated serine and threonine residues” in: Peptides 1992 (C.H. Schneider & A.N. Eberle, eds.) p. 167-168; Escom Science Publishers,1992.

Book Chapter

H.A. Remmer and G.B. Fields 2000. Chemical synthesis of peptides.  In: Peptides and Protein Drug Analysis (Ronald E. Reid, ed), p. 133-169, Marcel Dekker Inc, New York.

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