Transgenic Animal Model
The Transgenic Animal Model Core
was established in 1989 in response to the need for transgenic technology by University Investigators. The mission of the Transgenic Core is to provide access to transgenic animal technology in an efficient, effective manner. Researchers can use Transgenic Core laboratory space and resources side by side with staff members. Consultation in all phases of genome editing (CRISPR/Cas9), transgenic, and gene targeting research from experimental design to mouse breeding is freely available. The Core’s mission is to provide access to a complex technology so that investigators can focus their resources on research instead of developing tools for research.
Our Process
Consultation
Consultations are provided at no cost. We provide advice, as well as protocols and training, for every step of the process from experimental design to mouse breeding. Please contact us at any time with questions on how to proceed.
Project Request
To submit a service request, please log into MiCores.
Submissions
Core Testimonials
“As someone working with mouse mutants for more than 30 years, my latest experience with the Transgenic Animal Core was truly exceptional. All I did was give the Core a gene name. The Core designed the whole strategy, including the CRISPR guide RNAs and the template for introducing two LoxP site to make a conditional floxed allele. A process that would have taken many years was finished within 4 months, generating at least 3 independent founder mice with the correct targeted floxed allele. The speed and accuracy of gene targeting has never been better.”
Our Locations:
Medical Sciences Research Building (MSRB) II
General Information
734-647-2910
Our People
Email Us
News
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BRCF is Partnering with Rogel Cancer Center Shared Resources to Extend Our Reach
Michigan Medicine’s Rogel Cancer Center recently announced several new offerings coming to their Shared Resources program. Two BRCF Cores are now working to provide service to Rogel Cancer Center patrons. The first new offering is the Epigenomics and Epigenetics Shared Resource, …
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Supply Shortages Affecting the Advanced Genomics Core
The BRCF Advanced Genomics Core is currently facing multiple supply shortages. We are encountering lengthy backorders and long lead times for sole-sourced items. Additionally, many consumables and quality control reagents are now on allocation. This combination is limiting our ability to fulfill …
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