The Transgenic Animal Model Core

was established in 1989 in response to the need for transgenic technology by University Investigators. The mission of the Transgenic Core is to provide access to transgenic animal technology in an efficient, effective manner. Researchers can use Transgenic Core laboratory space and resources side by side with staff members. Consultation in all phases of genome editing (CRISPR/Cas9), transgenic, and gene targeting research from experimental design to mouse breeding is freely available. The Core’s mission is to provide access to a complex technology so that investigators can focus their resources on research instead of developing tools for research.

Our Process

Consultation

Consultations are provided at no cost. We provide advice, as well as protocols and training, for every step of the process from experimental design to mouse breeding. Please contact us at any time with questions on how to proceed.

Project Request

To submit a service request, please log into MiCores.

Submissions
Once prepared, submit all of your materials to the Core so that we may initiate your request.

Core Testimonials

“As someone working with mouse mutants for more than 30 years, my latest experience with the Transgenic Animal Core was truly exceptional. All I did was give the Core a gene name. The Core designed the whole strategy, including the CRISPR guide RNAs and the template for introducing two LoxP site to make a conditional floxed allele. A process that would have taken many years was finished within 4 months, generating at least 3 independent founder mice with the correct targeted floxed allele. The speed and accuracy of gene targeting has never been better.” 

Dr. Gregory Dressler

Our Locations:

Medical Sciences Research Building (MSRB) II

General Information

734-647-2910

Email Us

News

  • BRCF Core Holiday Hours for November 2023

    In observance of the upcoming November holidays, many of our cores have adjusted their operations. If you have questions about hours or access, please use the core’s contact information listed below. Advanced Genomics Core Core services will be unavailable after …

     
  • AGC Onboards Xenium!

    The Advanced Genomics Core has acquired the 10x Genomics Xenium, an instrument that enables transcriptomic analysis at a subcellular level while maintaining spatial context. This technology comes with pre-validated biologically relevant targets for tissue panels, and up to 100 additional …

         

Events

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