Transgenic Animal Model
The Transgenic Animal Model Core
was established in 1989 in response to the need for transgenic technology by University Investigators. The mission of the Transgenic Core is to provide access to transgenic animal technology in an efficient, effective manner. Researchers can use Transgenic Core laboratory space and resources side by side with staff members. Consultation in all phases of genome editing (CRISPR/Cas9), transgenic, and gene targeting research from experimental design to mouse breeding is freely available. The Core’s mission is to provide access to a complex technology so that investigators can focus their resources on research instead of developing tools for research.
Consultations are provided at no cost. We provide advice, as well as protocols and training, for every step of the process from experimental design to mouse breeding. Please contact us at any time with questions on how to proceed.
“As someone working with mouse mutants for more than 30 years, my latest experience with the Transgenic Animal Core was truly exceptional. All I did was give the Core a gene name. The Core designed the whole strategy, including the CRISPR guide RNAs and the template for introducing two LoxP site to make a conditional floxed allele. A process that would have taken many years was finished within 4 months, generating at least 3 independent founder mice with the correct targeted floxed allele. The speed and accuracy of gene targeting has never been better.”
Medical Sciences Research Building (MSRB) II
CRISPR/Cas9 Training Class Offered by TAMC, January 16 – 27, 2023
The University of Michigan Transgenic Animal Model Core will offer the CRISPR/Cas9 and Mouse ES Cell Training Class from January 16 through January 27. In this two-week long hands-on session, trainees will design, build, and validate CRISPR/Cas9 reagents in mouse …Event Breaking News
Epigenomics Core’s Faculty Director, Dana Dolinoy, Ph.D. in TIME’s Article: For Camp Lejeune Victims Exposed to Toxic Water, a New Law Promises Compensation—and Closure
Commenting on the exposure to toxicants in modern Western life, Dana Dolinoy, Ph.D., professor of environmental health sciences and nutritional sciences and faculty director for the Epigenomics Core, stated: “We can be exposed through the air we breathe, the water …Uncategorized Staff Case Studies & Research Profiles Breaking News