Vector

In-house viral and plasmid stocks ready the next day

 

About the Vector Core

The Vector Core produces biological products (gene transfer vectors) that facilitate the transfer of specific genes into either normal or aberrant cells. The Vector Core also provides intellectual and technical advice to researchers regarding the optimal use of these systems. Gene transfer vectors require special handling precautions, and manufacturing systems that lend themselves to a core structure that optimizes efficiencies of scale and cost to the research community. The specific objectives of the Vector Core are to:

 

  1. Provide a Core laboratory for the construction, purification, and characterization of recombinant vectors containing genes relevant to the study of disease models for use as in vitro and in vivo gene transfer reagents. These systems include both non-viral (expression plasmid) and viral (recombinant lentivirus, recombinant retrovirus, and recombinant adenovirus) technologies;
  2. Collaborate closely with researchers to ensure the Vector Core provides the platforms our customers require, and to institute the use of new technologies;
  3. Maintain qualified staff and provide high quality, cost-effective products to our researchers.

Process

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Getting Started

To begin work with the Vector Core, you will first need to register with MiCores and complete training. Please see the Training page for more information on how to get started.

Consultation

For questions regarding your specific needs or project goals please contact Vector Core Director, Tom Lanigan, to set up a consultation.

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Ordering

Please visit the Products & Services page for more detailed information on what we offer. To request products and services, login to MiCores.

Vector Core by the Numbers

Principal Investigators Worked With (FY17)

Grants Serviced (FY17)

Founded

Events

  • Tools & Technology Seminar Series – Andrei Lomize

    The DCMB Tools and Technology Seminar Series is presented in room 2036, Palmer Commons each Thursday, at 12 noon EST. Each seminar highlights a tool or technology, that is under development or in current use, that is of interest to …

     
  • Tools & Technology Seminar Series – Matt Cybulsky

    The DCMB Tools and Technology Seminar Series is presented in room 2036, Palmer Commons each Thursday, at 12 noon EST. Each seminar highlights a tool or technology, that is under development or in current use, that is of interest to …

     

News

  • Microscopy & Image Analysis Laboratory Phasing Out Histology Services

    In order to better focus on providing access to state-of-the-art microscopy imaging and analysis, the Microscopy & Image Analysis Laboratory (MIL) is phasing out all light microscopy histology services, including cryosectioning, vibratome sectioning, and paraffin processing/embedding/sectioning. Importantly, the MIL will continue to …

     
  • Medical School Office of Research Seeks a Faculty Director for the BRCF DNA Sequencing Core

    The current and founding Director of the DNA Sequencing Core, Bob Lyons, Ph.D., will be retiring in September. To that end, the Medical School Office of Research is accepting nominations for a Faculty Director for the Biomedical Research Core Facilities …