Vector

In-house viral and plasmid stocks ready the next day

About the Vector Core

The Vector Core produces biological products (gene transfer vectors) that facilitate the transfer of specific genes into either normal or aberrant cells. The Vector Core also provides intellectual and technical advice to researchers regarding the optimal use of these systems. Gene transfer vectors require special handling precautions, and manufacturing systems that lend themselves to a core structure that optimizes efficiencies of scale and cost to the research community. The specific objectives of the Vector Core are to:

 

  1. Provide a Core laboratory for the construction, purification, and characterization of recombinant vectors containing genes relevant to the study of disease models for use as in vitro and in vivo gene transfer reagents. These systems include both non-viral (expression plasmid) and viral (recombinant lentivirus, recombinant retrovirus, and recombinant adenovirus) technologies;
  2. Collaborate closely with researchers to ensure the Vector Core provides the platforms our customers require, and to institute the use of new technologies;
  3. Maintain qualified staff and provide high quality, cost-effective products to our researchers.

Process

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Getting Started

To begin work with the Vector Core, you will first need to register with MiCores and complete training. Please see the Training page for more information on how to get started.

Consultation

For questions regarding your specific needs or project goals please contact Vector Core Director, Tom Lanigan, to set up a consultation.

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Ordering

Please visit the Products & Services page for more detailed information on what we offer. To request products and services, login to MiCores.

Vector Core by the Numbers

Principal Investigators Worked With (FY17)

Grants Serviced (FY17)

Founded

Events

  • Explore Advanced Applications Using the Ze5 Cell Analyzer

    Training Hosted by Bio-Rad & the Flow Cytometry Core Join Bio-Rad Field Application Specialist Xiaoti Guo, Ph.D., as we explore some advanced applications using the ZE5 Flow Cytometer. This technology allows researchers to push the limits of conventional flow cytometry. …

       
  • DNA Sequencing Core Symposium: Honoring Bob Lyons

    DNA Sequencing Core Faculty Director Bob Lyons, Ph.D., is ending his stellar 23-year career at the University of Michigan on Thursday, November 8 with a symposium. Join us in celebrating his retirement. The event will include: Remarks from Steve Kunkel, …

     

News

  • Welcome the NovaSeq 6000

    The NovaSeq 6000 combines 2 color SBS chemistry with the nanowell patterned flow cell. There are four flow cells options, SP, S1, S2, and the S4. There are two different ways to load the Flow cell, individual lane loading (XP) …

         
  • Meet Roland: Vector Core’s Newest Member

    Roland Hilgarth, Ph.D. In August, Roland Hilgarth, Ph.D., joined the Vector Core as a Research Lab Specialist Lead. While growing up in St. Louis, MO, he often found himself in his parent’s garden, studying bugs and determining which could help, …