Vector

In-house viral and plasmid stocks ready the next day

About the Vector Core

The Vector Core produces biological products (gene transfer vectors) that facilitate the transfer of specific genes into either normal or aberrant cells. The Vector Core also provides intellectual and technical advice to researchers regarding the optimal use of these systems. Gene transfer vectors require special handling precautions, and manufacturing systems that lend themselves to a core structure that optimizes efficiencies of scale and cost to the research community. The specific objectives of the Vector Core are to:

 

  1. Provide a Core laboratory for the construction, purification, and characterization of recombinant vectors containing genes relevant to the study of disease models for use as in vitro and in vivo gene transfer reagents. These systems include both non-viral (expression plasmid) and viral (recombinant lentivirus, recombinant retrovirus, and recombinant adenovirus) technologies;
  2. Collaborate closely with researchers to ensure the Vector Core provides the platforms our customers require, and to institute the use of new technologies;
  3. Maintain qualified staff and provide high quality, cost-effective products to our researchers.

Process

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Getting Started

To begin work with the Vector Core, you will first need to register with MiCores and complete training. Please see the Training page for more information on how to get started.

Consultation

For questions regarding your specific needs or project goals please contact Vector Core Director, Tom Lanigan, to set up a consultation.

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Ordering

Please visit the Products & Services page for more detailed information on what we offer. To request products and services, login to MiCores.

Vector Core by the Numbers

Principal Investigators Worked With (FY18)

Grants Serviced (FY18)

Founded

Events

  • AGC and 10x Genomics Office Hours

    Bring your experimental design or analysis questions for our experts! Meet your Advanced Genomics Core team and learn more about the new and exciting technologies we are bringing to U-M.  Office hours will be held in the Taubman Library. Representatives …

     
  • 10x Genomics Visium Spatial Gene Expression Seminar

    Sponsored by the Advanced Genomics Core and featuring Keith Cockrum, Technical Sales Specialist, 10x Genomics The ability to discern spatial gene expression differences in complex biological systems is critical to our understanding of developmental biology and the progression of disease. However, …

     

News

  • AGC Increases Instrumentation Offerings with New Illumina MiSeq & ONT GridION System

    The Advanced Genomics Core (AGC) is pleased to announce the addition of a second Illumina MiSeq to their available instrumentation. The Illumina MiSeq, a small-scale next-generation DNA sequencer, boasts read lengths up to 600 bp and yields up to 25 …

       
  • CRISPR/Cas9 Training Class Offered by TAMC, Nov. 4 – Nov. 15

    The University of Michigan Transgenic Animal Model Core will offer the CRISPR/Cas9 and Mouse ES Cell Training Class from November 4 through November 15. In this two-week long hands-on session trainees will design, build, and validate CRISPR/Cas9 reagents in mouse ES cells. Trainees will …